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Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model.

Tagge CA, Fisher AM, Minaeva OV, Gaudreau-Balderrama A, Moncaster JA, Zhang XL, Wojnarowicz MW, Casey N, Lu H, Kokiko-Cochran ON, Saman S, Ericsson M, Onos KD, Veksler R, Senatorov VV Jr, Kondo A, Zhou XZ, Miry O, Vose LR, Gopaul KR, Upreti C, Nowinski CJ, Cantu RC, Alvarez VE, Hildebrandt AM, Franz ES, Konrad J, Hamilton JA, Hua N, Tripodis Y, Anderson AT, Howell GR, Kaufer D, Hall GF, Lu KP, Ransohoff RM, Cleveland RO, Kowall NW, Stein TD, Lamb BT, Huber BR, Moss WC, Friedman A, Stanton PK, McKee AC, Goldstein LE.

Brain. 2018 Feb 1;141(2):422-458. doi: 10.1093/brain/awx350.


Age of first exposure to American football and long-term neuropsychiatric and cognitive outcomes.

Alosco ML, Kasimis AB, Stamm JM, Chua AS, Baugh CM, Daneshvar DH, Robbins CA, Mariani M, Hayden J, Conneely S, Au R, Torres A, McClean MD, McKee AC, Cantu RC, Mez J, Nowinski CJ, Martin BM, Chaisson CE, Tripodis Y, Stern RA.

Transl Psychiatry. 2017 Sep 19;7(9):e1236. doi: 10.1038/tp.2017.197.


Evolution of Patient-Reported Outcomes and Their Role in Multiple Sclerosis Clinical Trials.

Nowinski CJ, Miller DM, Cella D.

Neurotherapeutics. 2017 Oct;14(4):934-944. doi: 10.1007/s13311-017-0571-6. Review.


Computerized Adaptive Testing in Pediatric Brain Tumor Clinics.

Lai JS, Beaumont JL, Nowinski CJ, Cella D, Hartsell WF, Han-Chih Chang J, Manley PE, Goldman S.

J Pain Symptom Manage. 2017 Sep;54(3):289-297. doi: 10.1016/j.jpainsymman.2017.05.008. Epub 2017 Aug 8.


Clinicopathological Evaluation of Chronic Traumatic Encephalopathy in Players of American Football.

Mez J, Daneshvar DH, Kiernan PT, Abdolmohammadi B, Alvarez VE, Huber BR, Alosco ML, Solomon TM, Nowinski CJ, McHale L, Cormier KA, Kubilus CA, Martin BM, Murphy L, Baugh CM, Montenigro PH, Chaisson CE, Tripodis Y, Kowall NW, Weuve J, McClean MD, Cantu RC, Goldstein LE, Katz DI, Stern RA, Stein TD, McKee AC.

JAMA. 2017 Jul 25;318(4):360-370. doi: 10.1001/jama.2017.8334.


Utility of providing a concussion definition in the assessment of concussion history in former NFL players.

Alosco ML, Jarnagin J, Tripodis Y, Martin B, Chaisson C, Baugh CM, Torres A, Nowinski CJ, Cantu RC, Stern RA.

Brain Inj. 2017;31(8):1116-1123. doi: 10.1080/02699052.2017.1294709. Epub 2017 May 4.


Patient-Reported Outcomes in Performance Measurement.

Cella D, Hahn EA, Jensen SE, Butt Z, Nowinski CJ, Rothrock N, Lohr KN.

Research Triangle Park (NC): RTI Press; 2015 Sep.


Imaging of Glial Cell Activation and White Matter Integrity in Brains of Active and Recently Retired National Football League Players.

Coughlin JM, Wang Y, Minn I, Bienko N, Ambinder EB, Xu X, Peters ME, Dougherty JW, Vranesic M, Koo SM, Ahn HH, Lee M, Cottrell C, Sair HI, Sawa A, Munro CA, Nowinski CJ, Dannals RF, Lyketsos CG, Kassiou M, Smith G, Caffo B, Mori S, Guilarte TR, Pomper MG.

JAMA Neurol. 2017 Jan 1;74(1):67-74. doi: 10.1001/jamaneurol.2016.3764.


A PROMIS Measure of Neuropathic Pain Quality.

Askew RL, Cook KF, Keefe FJ, Nowinski CJ, Cella D, Revicki DA, Morgan DeWitt EM, Michaud K, Trence DL, Amtmann D.

Value Health. 2016 Jul-Aug;19(5):623-30. doi: 10.1016/j.jval.2016.02.009. Epub 2016 Apr 6.


Cognitive Reserve as a Modifier of Clinical Expression in Chronic Traumatic Encephalopathy: A Preliminary Examination.

Alosco ML, Mez J, Kowall NW, Stein TD, Goldstein LE, Cantu RC, Katz DI, Solomon TM, Kiernan PT, Murphy L, Abdolmohammadi B, Daneshvar D, Montenigro PH, Nowinski CJ, Stern RA, McKee AC.

J Neuropsychiatry Clin Neurosci. 2017 Winter;29(1):6-12. doi: 10.1176/appi.neuropsych.16030043. Epub 2016 Aug 19.


Cumulative Head Impact Exposure Predicts Later-Life Depression, Apathy, Executive Dysfunction, and Cognitive Impairment in Former High School and College Football Players.

Montenigro PH, Alosco ML, Martin BM, Daneshvar DH, Mez J, Chaisson CE, Nowinski CJ, Au R, McKee AC, Cantu RC, McClean MD, Stern RA, Tripodis Y.

J Neurotrauma. 2017 Jan 15;34(2):328-340. doi: 10.1089/neu.2016.4413. Epub 2016 Jun 15.


Neuro-QoL health-related quality of life measurement system: Validation in Parkinson's disease.

Nowinski CJ, Siderowf A, Simuni T, Wortman C, Moy C, Cella D.

Mov Disord. 2016 May;31(5):725-33. doi: 10.1002/mds.26546. Epub 2016 Feb 26. Review.


Assessing clinicopathological correlation in chronic traumatic encephalopathy: rationale and methods for the UNITE study.

Mez J, Solomon TM, Daneshvar DH, Murphy L, Kiernan PT, Montenigro PH, Kriegel J, Abdolmohammadi B, Fry B, Babcock KJ, Adams JW, Bourlas AP, Papadopoulos Z, McHale L, Ardaugh BM, Martin BR, Dixon D, Nowinski CJ, Chaisson C, Alvarez VE, Tripodis Y, Stein TD, Goldstein LE, Katz DI, Kowall NW, Cantu RC, Stern RA, McKee AC.

Alzheimers Res Ther. 2015 Oct 12;7(1):62. doi: 10.1186/s13195-015-0148-8.


Validating Neuro-QoL short forms and targeted scales with people who have multiple sclerosis.

Miller DM, Bethoux F, Victorson D, Nowinski CJ, Buono S, Lai JS, Wortman K, Burns JL, Moy C, Cella D.

Mult Scler. 2016 May;22(6):830-41. doi: 10.1177/1352458515599450. Epub 2015 Aug 3.


Beta-amyloid deposition in chronic traumatic encephalopathy.

Stein TD, Montenigro PH, Alvarez VE, Xia W, Crary JF, Tripodis Y, Daneshvar DH, Mez J, Solomon T, Meng G, Kubilus CA, Cormier KA, Meng S, Babcock K, Kiernan P, Murphy L, Nowinski CJ, Martin B, Dixon D, Stern RA, Cantu RC, Kowall NW, McKee AC.

Acta Neuropathol. 2015 Jul;130(1):21-34. doi: 10.1007/s00401-015-1435-y. Epub 2015 May 6.


Self-Efficacy Buffers the Relationship between Educational Disadvantage and Executive Functioning.

Zahodne LB, Nowinski CJ, Gershon RC, Manly JJ.

J Int Neuropsychol Soc. 2015 Apr;21(4):297-304. doi: 10.1017/S1355617715000193. Epub 2015 Apr 16.


Validation of the Neuro-QoL measurement system in children with epilepsy.

Lai JS, Nowinski CJ, Zelko F, Wortman K, Burns J, Nordli DR, Cella D.

Epilepsy Behav. 2015 May;46:209-14. doi: 10.1016/j.yebeh.2015.02.038. Epub 2015 Apr 7.


Changes in the neurochemistry of athletes with repetitive brain trauma: preliminary results using localized correlated spectroscopy.

Lin AP, Ramadan S, Stern RA, Box HC, Nowinski CJ, Ross BD, Mountford CE.

Alzheimers Res Ther. 2015 Mar 15;7(1):13. doi: 10.1186/s13195-015-0094-5. eCollection 2015.


Depressive symptoms are more strongly related to executive functioning and episodic memory among African American compared with non-Hispanic White older adults.

Zahodne LB, Nowinski CJ, Gershon RC, Manly JJ.

Arch Clin Neuropsychol. 2014 Nov;29(7):663-9. doi: 10.1093/arclin/acu045. Epub 2014 Oct 3.


Concussion reporting intention: a valuable metric for predicting reporting behavior and evaluating concussion education.

Kroshus E, Baugh CM, Daneshvar DH, Nowinski CJ, Cantu RC.

Clin J Sport Med. 2015 May;25(3):243-7. doi: 10.1097/JSM.0000000000000137.


The impact of symptom burden on patient quality of life in chronic myeloid leukemia.

Cella D, Nowinski CJ, Frankfurt O.

Oncology. 2014;87(3):133-47. doi: 10.1159/000362816. Epub 2014 Jul 8. Review.


The cognition battery of the NIH toolbox for assessment of neurological and behavioral function: validation in an adult sample.

Weintraub S, Dikmen SS, Heaton RK, Tulsky DS, Zelazo PD, Slotkin J, Carlozzi NE, Bauer PJ, Wallner-Allen K, Fox N, Havlik R, Beaumont JL, Mungas D, Manly JJ, Moy C, Conway K, Edwards E, Nowinski CJ, Gershon R.

J Int Neuropsychol Soc. 2014 Jul;20(6):567-78. doi: 10.1017/S1355617714000320. Epub 2014 Jun 24.


Self-reported concussion history: impact of providing a definition of concussion.

Robbins CA, Daneshvar DH, Picano JD, Gavett BE, Baugh CM, Riley DO, Nowinski CJ, McKee AC, Cantu RC, Stern RA.

Open Access J Sports Med. 2014 May 7;5:99-103. doi: 10.2147/OAJSM.S58005. eCollection 2014.


HD-PRO-TRIAD™ Validation: A Patient-reported Instrument for the Symptom Triad of Huntington's Disease.

Carlozzi NE, Victorson D, Sung V, Beaumont JL, Cheng W, Gorin B, Duh MS, Samuelson D, Tulsky D, Gutierrez S, Nowinski CJ, Mueller A, Shen V, Frank S.

Tremor Other Hyperkinet Mov (N Y). 2014 Apr 14;4:223. doi: 10.7916/D8PN93NZ. eCollection 2014.


Identifying Motor, Emotional-Behavioral, and Cognitive Deficits that Comprise the Triad of HD Symptoms from Patient, Caregiver, and Provider Perspectives.

Victorson D, Carlozzi NE, Frank S, Beaumont JL, Cheng W, Gorin B, Duh MS, Samuelson D, Tulsky D, Gutierrez S, Nowinski CJ, Mueller A, Shen V, Sung V.

Tremor Other Hyperkinet Mov (N Y). 2014 Apr 14;4:224. doi: 10.7916/D8JW8BWS. eCollection 2014.


Which psychosocial factors best predict cognitive performance in older adults?

Zahodne LB, Nowinski CJ, Gershon RC, Manly JJ.

J Int Neuropsychol Soc. 2014 May;20(5):487-95. doi: 10.1017/S1355617714000186. Epub 2014 Mar 31.


Clinical presentation of chronic traumatic encephalopathy.

Stern RA, Daneshvar DH, Baugh CM, Seichepine DR, Montenigro PH, Riley DO, Fritts NG, Stamm JM, Robbins CA, McHale L, Simkin I, Stein TD, Alvarez VE, Goldstein LE, Budson AE, Kowall NW, Nowinski CJ, Cantu RC, McKee AC.

Neurology. 2013 Sep 24;81(13):1122-9. doi: 10.1212/WNL.0b013e3182a55f7f. Epub 2013 Aug 21.


NCAA concussion education in ice hockey: an ineffective mandate.

Kroshus E, Daneshvar DH, Baugh CM, Nowinski CJ, Cantu RC.

Br J Sports Med. 2014 Jan;48(2):135-40. doi: 10.1136/bjsports-2013-092498. Epub 2013 Aug 16.


I. NIH Toolbox Cognition Battery (CB): introduction and pediatric data.

Weintraub S, Bauer PJ, Zelazo PD, Wallner-Allen K, Dikmen SS, Heaton RK, Tulsky DS, Slotkin J, Blitz DL, Carlozzi NE, Havlik RJ, Beaumont JL, Mungas D, Manly JJ, Borosh BG, Nowinski CJ, Gershon RC.

Monogr Soc Res Child Dev. 2013 Aug;78(4):1-15. doi: 10.1111/mono.12031.


Cognition assessment using the NIH Toolbox.

Weintraub S, Dikmen SS, Heaton RK, Tulsky DS, Zelazo PD, Bauer PJ, Carlozzi NE, Slotkin J, Blitz D, Wallner-Allen K, Fox NA, Beaumont JL, Mungas D, Nowinski CJ, Richler J, Deocampo JA, Anderson JE, Manly JJ, Borosh B, Havlik R, Conway K, Edwards E, Freund L, King JW, Moy C, Witt E, Gershon RC.

Neurology. 2013 Mar 12;80(11 Suppl 3):S54-64. doi: 10.1212/WNL.0b013e3182872ded.


Input on NIH Toolbox inclusion criteria: surveying the end-user community.

Nowinski CJ, Victorson D, Debb SM, Gershon RC.

Neurology. 2013 Mar 12;80(11 Suppl 3):S7-12. doi: 10.1212/WNL.0b013e3182872e4c.


NIH toolbox for assessment of neurological and behavioral function.

Gershon RC, Wagster MV, Hendrie HC, Fox NA, Cook KF, Nowinski CJ.

Neurology. 2013 Mar 12;80(11 Suppl 3):S2-6. doi: 10.1212/WNL.0b013e3182872e5f.


What is the NIH toolbox, and what will it mean to neurology?

Bleck TP, Nowinski CJ, Gershon R, Koroshetz WJ.

Neurology. 2013 Mar 5;80(10):874-5. doi: 10.1212/WNL.0b013e3182872ea0. No abstract available.


Profile of self-reported problems with executive functioning in college and professional football players.

Seichepine DR, Stamm JM, Daneshvar DH, Riley DO, Baugh CM, Gavett BE, Tripodis Y, Martin B, Chaisson C, McKee AC, Cantu RC, Nowinski CJ, Stern RA.

J Neurotrauma. 2013 Jul 15;30(14):1299-304. doi: 10.1089/neu.2012.2690. Epub 2013 Jul 11.


The spectrum of disease in chronic traumatic encephalopathy.

McKee AC, Stern RA, Nowinski CJ, Stein TD, Alvarez VE, Daneshvar DH, Lee HS, Wojtowicz SM, Hall G, Baugh CM, Riley DO, Kubilus CA, Cormier KA, Jacobs MA, Martin BR, Abraham CR, Ikezu T, Reichard RR, Wolozin BL, Budson AE, Goldstein LE, Kowall NW, Cantu RC.

Brain. 2013 Jan;136(Pt 1):43-64. doi: 10.1093/brain/aws307. Epub 2012 Dec 2. Erratum in: Brain. 2013 Oct;136(Pt 10):e255.


Effectiveness of the SLICE program for youth concussion education.

Bagley AF, Daneshvar DH, Schanker BD, Zurakowski D, dʼHemecourt CA, Nowinski CJ, Cantu RC, Goulet K.

Clin J Sport Med. 2012 Sep;22(5):385-9.


Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model.

Goldstein LE, Fisher AM, Tagge CA, Zhang XL, Velisek L, Sullivan JA, Upreti C, Kracht JM, Ericsson M, Wojnarowicz MW, Goletiani CJ, Maglakelidze GM, Casey N, Moncaster JA, Minaeva O, Moir RD, Nowinski CJ, Stern RA, Cantu RC, Geiling J, Blusztajn JK, Wolozin BL, Ikezu T, Stein TD, Budson AE, Kowall NW, Chargin D, Sharon A, Saman S, Hall GF, Moss WC, Cleveland RO, Tanzi RE, Stanton PK, McKee AC.

Sci Transl Med. 2012 May 16;4(134):134ra60. doi: 10.1126/scitranslmed.3003716.


Neuro-QOL: brief measures of health-related quality of life for clinical research in neurology.

Cella D, Lai JS, Nowinski CJ, Victorson D, Peterman A, Miller D, Bethoux F, Heinemann A, Rubin S, Cavazos JE, Reder AT, Sufit R, Simuni T, Holmes GL, Siderowf A, Wojna V, Bode R, McKinney N, Podrabsky T, Wortman K, Choi S, Gershon R, Rothrock N, Moy C.

Neurology. 2012 Jun 5;78(23):1860-7. doi: 10.1212/WNL.0b013e318258f744. Epub 2012 May 9.


Chronic traumatic encephalopathy: neurodegeneration following repetitive concussive and subconcussive brain trauma.

Baugh CM, Stamm JM, Riley DO, Gavett BE, Shenton ME, Lin A, Nowinski CJ, Cantu RC, McKee AC, Stern RA.

Brain Imaging Behav. 2012 Jun;6(2):244-54. doi: 10.1007/s11682-012-9164-5. Review.


Long-term consequences of repetitive brain trauma: chronic traumatic encephalopathy.

Stern RA, Riley DO, Daneshvar DH, Nowinski CJ, Cantu RC, McKee AC.

PM R. 2011 Oct;3(10 Suppl 2):S460-7. doi: 10.1016/j.pmrj.2011.08.008. Review.


Long-term consequences: effects on normal development profile after concussion.

Daneshvar DH, Riley DO, Nowinski CJ, McKee AC, Stern RA, Cantu RC.

Phys Med Rehabil Clin N Am. 2011 Nov;22(4):683-700, ix. doi: 10.1016/j.pmr.2011.08.009. Epub 2011 Sep 23. Review.


Clinical appraisal of chronic traumatic encephalopathy: current perspectives and future directions.

Gavett BE, Cantu RC, Shenton M, Lin AP, Nowinski CJ, McKee AC, Stern RA.

Curr Opin Neurol. 2011 Dec;24(6):525-31. doi: 10.1097/WCO.0b013e32834cd477. Review.


Neuro-QOL and the NIH Toolbox: implications for epilepsy.

Nowinski CJ, Victorson D, Cavazos JE, Gershon R, Cella D.

Therapy. 2010 Sep 1;7(5):533-540.


Helmets and mouth guards: the role of personal equipment in preventing sport-related concussions.

Daneshvar DH, Baugh CM, Nowinski CJ, McKee AC, Stern RA, Cantu RC.

Clin Sports Med. 2011 Jan;30(1):145-63, x. doi: 10.1016/j.csm.2010.09.006. Review.


The epidemiology of sport-related concussion.

Daneshvar DH, Nowinski CJ, McKee AC, Cantu RC.

Clin Sports Med. 2011 Jan;30(1):1-17, vii. doi: 10.1016/j.csm.2010.08.006. Review.


TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy.

McKee AC, Gavett BE, Stern RA, Nowinski CJ, Cantu RC, Kowall NW, Perl DP, Hedley-Whyte ET, Price B, Sullivan C, Morin P, Lee HS, Kubilus CA, Daneshvar DH, Wulff M, Budson AE.

J Neuropathol Exp Neurol. 2010 Sep;69(9):918-29. doi: 10.1097/NEN.0b013e3181ee7d85.


Mild traumatic brain injury: a risk factor for neurodegeneration.

Gavett BE, Stern RA, Cantu RC, Nowinski CJ, McKee AC.

Alzheimers Res Ther. 2010 Jun 25;2(3):18. doi: 10.1186/alzrt42.


Chronic traumatic encephalopathy in athletes: progressive tauopathy after repetitive head injury.

McKee AC, Cantu RC, Nowinski CJ, Hedley-Whyte ET, Gavett BE, Budson AE, Santini VE, Lee HS, Kubilus CA, Stern RA.

J Neuropathol Exp Neurol. 2009 Jul;68(7):709-35. doi: 10.1097/NEN.0b013e3181a9d503. Review.


A qualitative study of quality of life after stroke: the importance of social relationships.

Lynch EB, Butt Z, Heinemann A, Victorson D, Nowinski CJ, Perez L, Cella D.

J Rehabil Med. 2008 Jul;40(7):518-23. doi: 10.2340/16501977-0203.


The impact of converting to an electronic health record on organizational culture and quality improvement.

Nowinski CJ, Becker SM, Reynolds KS, Beaumont JL, Caprini CA, Hahn EA, Peres A, Arnold BJ.

Int J Med Inform. 2007 Jun;76 Suppl 1:S174-83. Epub 2006 Jul 14.


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