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Apolipoprotein E plays crucial roles in maintaining bone mass by promoting osteoblast differentiation via ERK1/2 pathway and by suppressing osteoclast differentiation via c-Fos, NFATc1, and NF-κB pathway.

Noguchi T, Ebina K, Hirao M, Otsuru S, Guess AJ, Kawase R, Ohama T, Yamashita S, Etani Y, Okamura G, Yoshikawa H.

Biochem Biophys Res Commun. 2018 Jun 14. pii: S0006-291X(18)31367-6. doi: 10.1016/j.bbrc.2018.06.055. [Epub ahead of print]


Elevated Plasma D-Dimer Level Is Associated With Short-Term Risk of Ischemic Stroke in Patients With Acute Heart Failure.

Hamatani Y, Nagai T, Nakai M, Nishimura K, Honda Y, Nakano H, Honda S, Iwakami N, Sugano Y, Asaumi Y, Aiba T, Noguchi T, Kusano K, Toyoda K, Yasuda S, Yokoyama H, Ogawa H, Anzai T; NaDEF Investigators.

Stroke. 2018 Jun 7. pii: STROKEAHA.118.021899. doi: 10.1161/STROKEAHA.118.021899. [Epub ahead of print]


A Synbiotic with Tumor Necrosis Factor-α Inhibitory Activity Ameliorates Experimental Jejunoileal Mucosal Injury.

Takahashi R, Noguchi T, Mizoguchi Y, Shimoyama T, Nakazawa T, Ikuta T.

Biomed Res Int. 2018 May 10;2018:9184093. doi: 10.1155/2018/9184093. eCollection 2018.


Procedural challenge of coronary catheterization for ST-segment elevation myocardial infarction in patient who underwent transcatheter aortic valve replacement using the CoreValveTM.

Aikawa Y, Kataoka Y, Kanaya T, Amaki M, Tahara Y, Asaumi Y, Kanzaki H, Noguchi T, Fujita T, Kobayashi J, Yasuda S.

Cardiovasc Diagn Ther. 2018 Apr;8(2):190-195. doi: 10.21037/cdt.2018.04.02.


C-X-C Motif Chemokine 12 Enhances Lipopolysaccharide-Induced Osteoclastogenesis and Bone Resorption In Vivo.

Shima K, Kimura K, Ishida M, Kishikawa A, Ogawa S, Qi J, Shen WR, Ohori F, Noguchi T, Marahleh A, Kitaura H.

Calcif Tissue Int. 2018 May 29. doi: 10.1007/s00223-018-0435-z. [Epub ahead of print]


Effects of β2-adrenergic agonists on periostin-induced adhesion, superoxide anion generation, and degranulation of human eosinophils.

Noguchi T, Nakagome K, Kobayashi T, Ueda Y, Soma T, Nakamoto H, Nagata M.

Allergol Int. 2018 May 15. pii: S1323-8930(18)30050-9. doi: 10.1016/j.alit.2018.04.007. [Epub ahead of print] No abstract available.


Clinical determinants of successful weaning from extracorporeal membrane oxygenation in patients with fulminant myocarditis.

Matsumoto M, Asaumi Y, Nakamura Y, Nakatani T, Nagai T, Kanaya T, Kawakami S, Honda S, Kataoka Y, Nakajima S, Seguchi O, Yanase M, Nishimura K, Miyamoto Y, Kusano K, Anzai T, Noguchi T, Fujita T, Kobayashi J, Ishibashi-Ueda H, Shimokawa H, Yasuda S.

ESC Heart Fail. 2018 May 14. doi: 10.1002/ehf2.12291. [Epub ahead of print]


Comparison of Long-Term Mortality in Patients With Previous Coronary Artery Bypass Grafting Who Underwent Percutaneous Coronary Intervention With Versus Without Optimal Medical Therapy.

Nakamura Y, Asaumi Y, Miyagi T, Nakai M, Nishimura K, Sugane H, Matama H, Kataoka Y, Miyamoto Y, Takeishi Y, Noguchi T, Yasuda S.

Am J Cardiol. 2018 Apr 12. pii: S0002-9149(18)30858-0. doi: 10.1016/j.amjcard.2018.04.009. [Epub ahead of print]


A case of giant cell arteritis mimicking vertebral dissection on contrast-enhanced magnetic resonance angiography.

Yashima A, Yamashita H, Yamada S, Noguchi T, Takahashi Y, Kaneko H.

Clin Exp Rheumatol. 2018 Mar-Apr;36 Suppl 111(2):178-179. Epub 2018 Apr 19. No abstract available.


Administration of Oxygen Ultra-Fine Bubbles Improves Nerve Dysfunction in a Rat Sciatic Nerve Crush Injury Model.

Matsuoka H, Ebina K, Tanaka H, Hirao M, Iwahashi T, Noguchi T, Suzuki K, Nishimoto S, Murase T, Yoshikawa H.

Int J Mol Sci. 2018 May 7;19(5). pii: E1395. doi: 10.3390/ijms19051395.


Iliac artery stent fracture associated with hip joint flexion.

Doi T, Kawarada O, Yagyu T, Noguchi T, Yasuda S.

Cardiovasc Interv Ther. 2018 May 5. doi: 10.1007/s12928-018-0525-x. [Epub ahead of print] No abstract available.


Marking Technique for Identification of Optimal Stent Landing Site With Optical Coherence Tomographic Imaging.

Nakamura Y, Kataoka Y, Asaumi Y, Noguchi T, Yasuda S.

JACC Cardiovasc Interv. 2018 May 28;11(10):e79-e80. doi: 10.1016/j.jcin.2018.03.012. Epub 2018 May 2. No abstract available.


Peripheral Artery Disease Associated With Myeloproliferative Disorders.

Nakagawa S, Kawarada O, Yagyu T, Matsuo J, Inoue Y, Noguchi T, Yasuda S.

JACC Cardiovasc Interv. 2018 Apr 27. pii: S1936-8798(18)30628-9. doi: 10.1016/j.jcin.2018.02.025. [Epub ahead of print] No abstract available.


Retrospective Study on Laser Treatment of Oral Vascular Lesions Using the "Leopard Technique": The Multiple Spot Irradiation Technique with a Single-Pulsed Wave.

Miyazaki H, Ohshiro T, Romeo U, Noguchi T, Maruoka Y, Gaimari G, Tomov G, Wada Y, Tanaka K, Ohshiro T, Asamura S.

Photomed Laser Surg. 2018 Jun;36(6):320-325. doi: 10.1089/pho.2017.4410. Epub 2018 May 2.


Modified Scarf Osteotomy with Medial Capsule Interposition for Hallux Valgus in Rheumatoid Arthritis: A Study of Cases Including Severe First Metatarsophalangeal Joint Destruction.

Kushioka J, Hirao M, Tsuboi H, Ebina K, Noguchi T, Nampei A, Tsuji S, Akita S, Hashimoto J, Yoshikawa H.

J Bone Joint Surg Am. 2018 May 2;100(9):765-776. doi: 10.2106/JBJS.17.00436.


Staphylococcus epidermidis meningitis in the absence of a neurosurgical device secondary to catheter-related bloodstream infection: a case report and review of the literature.

Noguchi T, Nagao M, Yamamoto M, Matsumura Y, Kitano T, Takaori-Kondo A, Ichiyama S.

J Med Case Rep. 2018 Apr 25;12(1):106. doi: 10.1186/s13256-018-1646-7.


Magnetic Resonance (MR) Imaging Assessment for Glossopharyngeal Neuralgia: Value of Three-Dimensional T2-Reversed MR Imaging (3D-T2R) in Conjunction with Other Modes of 3D MR Imaging.

Nishihara M, Noguchi T, Kawashima M, Azama S, Matsushima K, Irie H.

Pol J Radiol. 2017 Oct 20;82:638-644. doi: 10.12659/PJR.902896. eCollection 2017.


Evaluation of simultaneous binding of Chromomycin A3 to the multiple sites of DNA by the new restriction enzyme assay.

Murase H, Noguchi T, Sasaki S.

Bioorg Med Chem Lett. 2018 Jun 1;28(10):1832-1835. doi: 10.1016/j.bmcl.2018.04.013. Epub 2018 Apr 7.


Mortality and Sudden Cardiac Death Risk Stratification Using the Noninvasive Combination of Wide QRS Duration and Late Gadolinium Enhancement in Idiopathic Dilated Cardiomyopathy.

Marume K, Noguchi T, Tateishi E, Morita Y, Kamakura T, Ishibashi K, Noda T, Miura H, Nishimura K, Nakai M, Yamada N, Tsujita K, Anzai T, Kusano K, Ogawa H, Yasuda S.

Circ Arrhythm Electrophysiol. 2018 Apr;11(4):e006233. doi: 10.1161/CIRCEP.117.006233.


Fourier Transform Infrared Analysis of the S-State Cycle of Water Oxidation in the Microcrystals of Photosystem II.

Kato Y, Akita F, Nakajima Y, Suga M, Umena Y, Shen JR, Noguchi T.

J Phys Chem Lett. 2018 May 3;9(9):2121-2126. doi: 10.1021/acs.jpclett.8b00638. Epub 2018 Apr 23.


Evaluation of postoperative changes in vascularized iliac bone grafts used for mandibular reconstruction.

Noguchi T, Sarukawa S, Tsuchiya Y, Okada N, Hayasaka J, Sasaguri K, Nishino H, Jinbu Y, Mori Y.

Int J Oral Maxillofac Surg. 2018 Mar 29. pii: S0901-5027(18)30074-2. doi: 10.1016/j.ijom.2018.03.002. [Epub ahead of print]


Mandibular reconstruction with free fibula flaps in the elderly: a retrospective evaluation.

Sugiura Y, Sarukawa S, Hayasaka J, Kamochi H, Noguchi T, Mori Y.

Int J Oral Maxillofac Surg. 2018 Mar 23. pii: S0901-5027(18)30063-8. doi: 10.1016/j.ijom.2018.02.009. [Epub ahead of print]


Impact of iron deficiency on long-term clinical outcomes of hospitalized patients with heart failure.

Nakano H, Nagai T, Sundaram V, Nakai M, Nishimura K, Honda Y, Honda S, Iwakami N, Sugano Y, Asaumi Y, Aiba T, Noguchi T, Kusano K, Yokoyama H, Ogawa H, Yasuda S, Chikamori T, Anzai T; NaDEF investigators.

Int J Cardiol. 2018 Jun 15;261:114-118. doi: 10.1016/j.ijcard.2018.03.039. Epub 2018 Mar 11.


Intermineral oxygen three-isotope systematics of silicate minerals in equilibrated ordinary chondrites.

McDougal D, Nakashima D, Tenner TJ, Kita NT, Valley JW, Noguchi T.

Meteorit Planet Sci. 2017 Nov;52(11):2322-2342. doi: 10.1111/maps.12932. Epub 2017 Sep 1.


Optical coherence tomography-verified morphological correlates of high-intensity coronary plaques on non-contrast T1-weighted magnetic resonance imaging in patients with stable coronary artery disease.

Kanaya T, Noguchi T, Otsuka F, Asaumi Y, Kataoka Y, Morita Y, Miura H, Nakao K, Fujino M, Kawasaki T, Nishimura K, Inoue T, Narula J, Yasuda S.

Eur Heart J Cardiovasc Imaging. 2018 Mar 5. doi: 10.1093/ehjci/jey035. [Epub ahead of print]


Carcinogenicity of quinoline by drinking-water administration in rats and mice.

Matsumoto M, Kano H, Suzuki M, Noguchi T, Umeda Y, Fukushima S.

J Toxicol Sci. 2018;43(2):113-127. doi: 10.2131/jts.43.113.


Effect of heat-induced κ-casein dissociation on acid coagulation of milk.

Oka D, Ono W, Ohara S, Noguchi T, Takano K.

J Dairy Res. 2018 Feb;85(1):104-109. doi: 10.1017/S002202991700084X. No abstract available.


A High Level of Blood Urea Nitrogen Is a Significant Predictor for In-hospital Mortality in Patients with Acute Myocardial Infarction.

Horiuchi Y, Aoki J, Tanabe K, Nakao K, Ozaki Y, Kimura K, Ako J, Yasuda S, Noguchi T, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Hirohata A, Morita Y, Inoue T, Okamura A, Uematsu M, Hirata K, Shibata Y, Nakai M, Nishimura K, Miyamoto Y, Ishihara M; J-MINUET investigators.

Int Heart J. 2018 Mar 30;59(2):263-271. doi: 10.1536/ihj.17-009. Epub 2018 Feb 20.


Extensive Iliofemoral Occlusion After Aortobifemoral Bypass Occlusion: The Potential of Native Artery Recanalization.

Kaichi R, Kawarada O, Yagyu T, Noguchi T, Yasuda S.

JACC Cardiovasc Interv. 2018 May 28;11(10):1006-1008. doi: 10.1016/j.jcin.2017.11.037. Epub 2018 Feb 14. No abstract available.


Embolization of Neoatherosclerosis After Percutaneous Coronary Intervention: Insights From Near-Infrared Spectroscopy Imaging and Histopathological Analysis.

Nishihira K, Otsuka F, Kataoka Y, Asaumi Y, Kaneta K, Nakano H, Ohta-Ogo K, Ishibashi-Ueda H, Noguchi T, Yasuda S.

Circ Cardiovasc Interv. 2018 Feb;11(2):e006175. doi: 10.1161/CIRCINTERVENTIONS.117.006175. No abstract available.


Etizolam attenuates the reduction in cutaneous temperature induced in mice by exposure to synthetic predator odor.

Miyazono S, Hasegawa K, Miyazaki S, Sakakima H, Konno S, Meguro S, Sasajima H, Noguchi T, Osada K, Kashiwayanagi M.

Eur J Pharmacol. 2018 Apr 5;824:157-162. doi: 10.1016/j.ejphar.2018.02.015. Epub 2018 Feb 10.


The PICKING technique for self-expanding nitinol stent expansion of an extremely calcified lesion in the femoropopliteal artery: the tail makes the difference.

Funabashi S, Kawarada O, Yagyu T, Noguchi T, Yasuda S.

Cardiovasc Interv Ther. 2018 Feb 9. doi: 10.1007/s12928-018-0513-1. [Epub ahead of print] No abstract available.


Robust water desalination membranes against degradation using high loads of carbon nanotubes.

Ortiz-Medina J, Inukai S, Araki T, Morelos-Gomez A, Cruz-Silva R, Takeuchi K, Noguchi T, Kawaguchi T, Terrones M, Endo M.

Sci Rep. 2018 Feb 9;8(1):2748. doi: 10.1038/s41598-018-21192-5.


Long-term prognostic significance of urinary sodium concentration in patients with acute heart failure.

Honda S, Nagai T, Nishimura K, Nakai M, Honda Y, Nakano H, Iwakami N, Sugano Y, Asaumi Y, Aiba T, Noguchi T, Kusano K, Yokoyama H, Ogawa H, Yasuda S, Anzai T; NaDEF investigators.

Int J Cardiol. 2018 Mar 1;254:189-194. doi: 10.1016/j.ijcard.2017.08.053. Epub 2018 Jan 28.


Modulation of AKR1C2 by curcumin decreases testosterone production in prostate cancer.

Ide H, Lu Y, Noguchi T, Muto S, Okada H, Kawato S, Horie S.

Cancer Sci. 2018 Apr;109(4):1230-1238. doi: 10.1111/cas.13517. Epub 2018 Feb 19.


Supra-pharmacological concentration of capsaicin stimulates brown adipogenesis through induction of endoplasmic reticulum stress.

Kida R, Noguchi T, Murakami M, Hashimoto O, Kawada T, Matsui T, Funaba M.

Sci Rep. 2018 Jan 16;8(1):845. doi: 10.1038/s41598-018-19223-2.


Sex differences in impact of coronary artery calcification to predict coronary artery disease.

Nakao YM, Miyamoto Y, Higashi M, Noguchi T, Ohishi M, Kubota I, Tsutsui H, Kawasaki T, Furukawa Y, Yoshimura M, Morita H, Nishimura K, Kada A, Goto Y, Okamura T, Tei C, Tomoike H, Naito H, Yasuda S.

Heart. 2018 Jul;104(13):1118-1124. doi: 10.1136/heartjnl-2017-312151. Epub 2018 Jan 13.


Effect of eicosapentaenoic acid/docosahexaenoic acid on coronary high-intensity plaques detected with non-contrast T1-weighted imaging (the AQUAMARINE EPA/DHA study): study protocol for a randomized controlled trial.

Nakao K, Noguchi T, Asaumi Y, Morita Y, Kanaya T, Fujino M, Hosoda H, Yoneda S, Kawakami S, Nagai T, Nishihira K, Nakashima T, Kumasaka R, Arakawa T, Otsuka F, Nakanishi M, Kataoka Y, Tahara Y, Goto Y, Yamamoto H, Hamasaki T, Yasuda S.

Trials. 2018 Jan 8;19(1):12. doi: 10.1186/s13063-017-2353-1.


Removal of Hexavalent Chromium in Portland Cement Using Ground Granulated Blast-Furnace Slag Powder.

Bae S, Hikaru F, Kanematsu M, Yoshizawa C, Noguchi T, Yu Y, Ha J.

Materials (Basel). 2017 Dec 22;11(1). pii: E11. doi: 10.3390/ma11010011.


Noninvasive Coronary Plaque Imaging.

Noguchi T, Nakao K, Asaumi Y, Morita Y, Otsuka F, Kataoka Y, Hosoda H, Miura H, Fukuda T, Yasuda S.

J Atheroscler Thromb. 2018 Apr 1;25(4):281-293. doi: 10.5551/jat.RV17019. Epub 2017 Dec 9.


Site-level progression of periodontal disease during a follow-up period.

Nomura Y, Morozumi T, Nakagawa T, Sugaya T, Kawanami M, Suzuki F, Takahashi K, Abe Y, Sato S, Makino-Oi A, Saito A, Takano S, Minabe M, Nakayama Y, Ogata Y, Kobayashi H, Izumi Y, Sugano N, Ito K, Sekino S, Numabe Y, Fukaya C, Yoshinari N, Fukuda M, Noguchi T, Kono T, Umeda M, Fujise O, Nishimura F, Yoshimura A, Hara Y, Nakamura T, Noguchi K, Kakuta E, Hanada N, Takashiba S, Amitani Y, Yoshie H.

PLoS One. 2017 Dec 4;12(12):e0188670. doi: 10.1371/journal.pone.0188670. eCollection 2017.


Systemic cardiovascular inflammation associated with autoimmune disease.

Koga M, Kawarada O, Yagyu T, Ishibashi-Ueda H, Hirano T, Noguchi T, Yasuda S.

Vasc Med. 2017 Dec 1:1358863X17743808. doi: 10.1177/1358863X17743808. [Epub ahead of print] No abstract available.


TRIM48 Promotes ASK1 Activation and Cell Death through Ubiquitination-Dependent Degradation of the ASK1-Negative Regulator PRMT1.

Hirata Y, Katagiri K, Nagaoka K, Morishita T, Kudoh Y, Hatta T, Naguro I, Kano K, Udagawa T, Natsume T, Aoki J, Inada T, Noguchi T, Ichijo H, Matsuzawa A.

Cell Rep. 2017 Nov 28;21(9):2447-2457. doi: 10.1016/j.celrep.2017.11.007.


Evaluation of photosynthetic activities in thylakoid membranes by means of Fourier transform infrared spectroscopy.

Nagao R, Kitazaki S, Noguchi T.

Biochim Biophys Acta. 2018 Feb;1859(2):129-136. doi: 10.1016/j.bbabio.2017.11.004. Epub 2017 Nov 22.


Sensitivities of Simulated Source Contributions and Health Impacts of PM2.5 to Aerosol Models.

Morino Y, Ueda K, Takami A, Nagashima T, Tanabe K, Sato K, Noguchi T, Ariga T, Matsuhashi K, Ohara T.

Environ Sci Technol. 2017 Dec 19;51(24):14273-14282. doi: 10.1021/acs.est.7b04000. Epub 2017 Dec 8.


3D reconstruction of endoplasmic reticulum in a hydrocarbon-secreting green alga, Botryococcus braunii (Race B).

Suzuki R, Nishii I, Okada S, Noguchi T.

Planta. 2018 Mar;247(3):663-677. doi: 10.1007/s00425-017-2811-8. Epub 2017 Nov 22.


A lower eicosapentaenoic acid/arachidonic acid ratio is associated with in-hospital fatal arrhythmic events in patients with acute myocardial infarction: a J-MINUET substudy.

Hashimoto T, Ako J, Nakao K, Ozaki Y, Kimura K, Noguchi T, Yasuda S, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Hirohata A, Morita Y, Inoue T, Okamura A, Uematsu M, Hirata K, Tanabe K, Shibata Y, Owa M, Tsujita K, Funayama H, Kokubu N, Kozuma K, Uemura S, Toubaru T, Saku K, Ohshima S, Nakai M, Nishimura K, Miyamoto Y, Ogawa H, Ishihara M; J-MINUET investigators.

Heart Vessels. 2018 May;33(5):481-488. doi: 10.1007/s00380-017-1084-2. Epub 2017 Nov 16.


Influence of a dosing-time on toxicities induced by docetaxel, cisplatin and 5-fluorouracil in patients with oral squamous cell carcinoma; a cross-over pilot study.

Tsuchiya Y, Ushijima K, Noguchi T, Okada N, Hayasaka JI, Jinbu Y, Ando H, Mori Y, Kusama M, Fujimura A.

Chronobiol Int. 2018 Feb;35(2):289-294. doi: 10.1080/07420528.2017.1392551. Epub 2017 Nov 16.


Joint Gap in Mid-Flexion Is Not a Predictor of Postoperative Flexion Angle After Total Knee Arthroplasty.

Minoda Y, Nakagawa S, Sugama R, Ikawa T, Noguchi T, Hirakawa M.

J Arthroplasty. 2018 Mar;33(3):735-739. doi: 10.1016/j.arth.2017.10.030. Epub 2017 Nov 11.


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