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Items: 1 to 50 of 386

1.

Unsaturated diacylglycerol as a possible messenger for the activation of calcium-activated, phospholipid-dependent protein kinase system. 1979.

Takai Y, Kishimoto A, Kikkawa U, Mori T, Nishizuka Y.

Biochem Biophys Res Commun. 2012 Aug 31;425(3):571-7. doi: 10.1016/j.bbrc.2012.08.026. No abstract available.

PMID:
22925676
2.

Early studies of protein kinase C: a historical perspective.

Nishizuka Y, Kikkawa U.

Methods Mol Biol. 2003;233:9-18. No abstract available.

PMID:
12840494
3.

Discovery and prospect of protein kinase C research: epilogue.

Nishizuka Y.

J Biochem. 2003 Feb;133(2):155-8. Review. No abstract available.

4.

Protein kinase C isotypes and their specific functions: prologue.

Ohno S, Nishizuka Y.

J Biochem. 2002 Oct;132(4):509-11. Review. No abstract available.

5.

The family of protein kinase C and membrane lipid mediators.

Saito N, Kikkawa U, Nishizuka Y.

J Diabetes Complications. 2002 Jan-Feb;16(1):4-8. No abstract available.

PMID:
11872358
6.

The protein kinase C family and lipid mediators for transmembrane signaling and cell regulation.

Nishizuka Y.

Alcohol Clin Exp Res. 2001 May;25(5 Suppl ISBRA):3S-7S. Review.

PMID:
11391043
7.

Phosphorylation sites of protein kinase C delta in H2O2-treated cells and its activation by tyrosine kinase in vitro.

Konishi H, Yamauchi E, Taniguchi H, Yamamoto T, Matsuzaki H, Takemura Y, Ohmae K, Kikkawa U, Nishizuka Y.

Proc Natl Acad Sci U S A. 2001 Jun 5;98(12):6587-92. Epub 2001 May 29.

8.

Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B.

Takaishi H, Konishi H, Matsuzaki H, Ono Y, Shirai Y, Saito N, Kitamura T, Ogawa W, Kasuga M, Kikkawa U, Nishizuka Y.

Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):11836-41.

9.

Requirement of GM2 ganglioside activator for phospholipase D activation.

Nakamura S, Akisue T, Jinnai H, Hitomi T, Sarkar S, Miwa N, Okada T, Yoshida K, Kuroda S, Kikkawa U, Nishizuka Y.

Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12249-53.

10.

Ca2+ -independent cytosolic phospholipase A in HL-60 cells differentiating to granulocytes.

Hullin-Matsuda F, Tsujishita Y, Nishizuka Y.

FEBS Lett. 1997 Dec 8;419(1):117-20.

11.

Activation of protein kinase C by tyrosine phosphorylation in response to H2O2.

Konishi H, Tanaka M, Takemura Y, Matsuzaki H, Ono Y, Kikkawa U, Nishizuka Y.

Proc Natl Acad Sci U S A. 1997 Oct 14;94(21):11233-7.

12.

Taxonomy and function of C1 protein kinase C homology domains.

Hurley JH, Newton AC, Parker PJ, Blumberg PM, Nishizuka Y.

Protein Sci. 1997 Feb;6(2):477-80.

13.

Reconstitution of GTP-gamma-S-dependent phospholipase D activity with ARF, RhoA, and a soluble 36-kDa protein.

Shimooku K, Akisue T, Jinnai H, Hitomi T, Ogino C, Yoshida K, Nakamura S, Nishizuka Y.

FEBS Lett. 1996 Jun 3;387(2-3):141-4.

14.

Mammalian phospholipase D: phosphatidylethanolamine as an essential component.

Nakamura S, Kiyohara Y, Jinnai H, Hitomi T, Ogino C, Yoshida K, Nishizuka Y.

Proc Natl Acad Sci U S A. 1996 Apr 30;93(9):4300-4.

15.

Mammalian phospholipase D: activation by ammonium sulfate and nucleotides.

Nakamura S, Shimooku K, Akisue T, Jinnai H, Hitomi T, Kiyohara Y, Ogino C, Yoshida K, Nishizuka Y.

Proc Natl Acad Sci U S A. 1995 Dec 19;92(26):12319-22.

16.

The protein kinase C isoforms leading to MAP-kinase activation in CHO cells.

Yamaguchi K, Ogita K, Nakamura S, Nishizuka Y.

Biochem Biophys Res Commun. 1995 May 25;210(3):639-47.

PMID:
7539255
17.

Protein kinase C and lipid signaling for sustained cellular responses.

Nishizuka Y.

FASEB J. 1995 Apr;9(7):484-96. Review.

PMID:
7737456
18.

Lipid mediators and protein kinase C for intracellular signalling.

Nishizuka Y, Nakamura S.

Clin Exp Pharmacol Physiol Suppl. 1995 Dec;22(1):S202-3.

PMID:
9072357
19.

Regulation of phospholipase A2 in human leukemia cell lines: its implication for intracellular signaling.

Tsujishita Y, Asaoka Y, Nishizuka Y.

Proc Natl Acad Sci U S A. 1994 Jul 5;91(14):6274-8.

20.

Lipid mediators and protein kinase C activation for the intracellular signaling network.

Nakamura S, Nishizuka Y.

J Biochem. 1994 Jun;115(6):1029-34. Review.

21.

The protein kinase C family for neuronal signaling.

Tanaka C, Nishizuka Y.

Annu Rev Neurosci. 1994;17:551-67. Review. No abstract available.

PMID:
8210187
22.

Anti-idiotypic antibody identifies a consensus recognition site for phosphatidylserine common to protein kinase C and other cellular phosphatidylserine-binding proteins.

Igarashi K, Umeda M, Farooq R, Tokita S, Asaoka Y, Nishizuka Y, Inoue K.

Ann N Y Acad Sci. 1993 Dec 20;707:536-9. No abstract available.

PMID:
9137615
23.

Potential role of phospholipase A2 in HL-60 cell differentiation to macrophages induced by protein kinase C activation.

Asaoka Y, Yoshida K, Sasaki Y, Nishizuka Y.

Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):4917-21.

24.
25.

Possible role of mammalian secretory group II phospholipase A2 in T-lymphocyte activation: implication in propagation of inflammatory reaction.

Asaoka Y, Yoshida K, Sasaki Y, Nishizuka Y, Murakami M, Kudo I, Inoue K.

Proc Natl Acad Sci U S A. 1993 Jan 15;90(2):716-9.

26.

Protein kinase C for cell signaling: a possible link between phospholipases.

Nakamura S, Asaoka Y, Yoshida K, Sasaki Y, Nishizuka Y.

Adv Second Messenger Phosphoprotein Res. 1993;28:171-8. Review. No abstract available.

PMID:
8398400
27.

Cell division arrest induced by phorbol ester in CHO cells overexpressing protein kinase C-delta subspecies.

Watanabe T, Ono Y, Taniyama Y, Hazama K, Igarashi K, Ogita K, Kikkawa U, Nishizuka Y.

Proc Natl Acad Sci U S A. 1992 Nov 1;89(21):10159-63.

28.

Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C.

Nishizuka Y.

Science. 1992 Oct 23;258(5082):607-14. Review.

PMID:
1411571
29.

Protein kinase C, calcium and phospholipid degradation.

Asaoka Y, Nakamura S, Yoshida K, Nishizuka Y.

Trends Biochem Sci. 1992 Oct;17(10):414-7. Review.

PMID:
1455509
30.

Membrane phospholipid degradation and protein kinase C for cell signalling.

Nishizuka Y.

Neurosci Res. 1992 Oct;15(1-2):3-5. Review. No abstract available.

PMID:
1336582
31.

Expression of protein kinase C subspecies in rat retina.

Fujisawa N, Ogita K, Saito N, Nishizuka Y.

FEBS Lett. 1992 Sep 14;309(3):409-12.

32.

Role of lysophosphatidylcholine in T-lymphocyte activation: involvement of phospholipase A2 in signal transduction through protein kinase C.

Asaoka Y, Oka M, Yoshida K, Sasaki Y, Nishizuka Y.

Proc Natl Acad Sci U S A. 1992 Jul 15;89(14):6447-51.

33.

Platelet activation by simultaneous actions of diacylglycerol and unsaturated fatty acids.

Yoshida K, Asaoka Y, Nishizuka Y.

Proc Natl Acad Sci U S A. 1992 Jul 15;89(14):6443-6.

34.

Isolation and characterization of delta-subspecies of protein kinase C from rat brain.

Ogita K, Miyamoto S, Yamaguchi K, Koide H, Fujisawa N, Kikkawa U, Sahara S, Fukami Y, Nishizuka Y.

Proc Natl Acad Sci U S A. 1992 Mar 1;89(5):1592-6.

35.

Isolation and characterization of the epsilon subspecies of protein kinase C from rat brain.

Koide H, Ogita K, Kikkawa U, Nishizuka Y.

Proc Natl Acad Sci U S A. 1992 Feb 15;89(4):1149-53.

36.

Degradation of phospholipids and protein kinase C activation for the control of neuronal functions.

Shinomura T, Mishima H, Matsushima S, Asaoka Y, Yoshida K, Oka M, Nishizuka Y.

Adv Exp Med Biol. 1992;318:361-73. Review. No abstract available.

PMID:
1636504
37.

The signal-induced phospholipid degradation cascade and protein kinase C activation.

Asaoka Y, Yoshida K, Oka M, Shinomura T, Mishima H, Matsushima S, Nishizuka Y.

Ciba Found Symp. 1992;164:50-9; discussion 59-65. Review.

PMID:
1395935
38.

The family of protein kinase C in transmembrane signalling for cellular regulation.

Asaoka Y, Yoshida K, Oka M, Shinomura T, Koide H, Ogita K, Kikkawa U, Nishizuka Y.

J Nutr Sci Vitaminol (Tokyo). 1992;Spec No:7-12. Review.

PMID:
1297824
39.

Sustained activation of protein kinase C is essential to HL-60 cell differentiation to macrophage.

Aihara H, Asaoka Y, Yoshida K, Nishizuka Y.

Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11062-6.

40.

Protein kinase C in rat brain synaptosomes. Beta II-subspecies as a major isoform associated with membrane-skeleton elements.

Tanaka S, Tominaga M, Yasuda I, Kishimoto A, Nishizuka Y.

FEBS Lett. 1991 Dec 9;294(3):267-70.

41.

Metabolic rate of membrane-permeant diacylglycerol and its relation to human resting T-lymphocyte activation.

Asaoka Y, Oka M, Yoshida K, Nishizuka Y.

Proc Natl Acad Sci U S A. 1991 Oct 1;88(19):8681-5.

42.

Spontaneous development of autoimmune uveoretinitis in nude mice following reconstitution with embryonic rat thymus.

Ichikawa T, Taguchi O, Takahashi T, Ikeda H, Takeuchi M, Tanaka T, Usui M, Nishizuka Y.

Clin Exp Immunol. 1991 Oct;86(1):112-17.

43.
44.

Lysophosphatidylcholine as a possible second messenger synergistic to diacylglycerol and calcium ion for T-lymphocyte activation.

Asaoka Y, Oka M, Yoshida K, Nishizuka Y.

Biochem Biophys Res Commun. 1991 Aug 15;178(3):1378-85.

PMID:
1872854
45.

Synergistic action of diacylglycerol and unsaturated fatty acid for protein kinase C activation: its possible implications.

Shinomura T, Asaoka Y, Oka M, Yoshida K, Nishizuka Y.

Proc Natl Acad Sci U S A. 1991 Jun 15;88(12):5149-53.

46.
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48.
49.

Protein kinase C family and nervous function.

Nishizuka Y, Shearman MS, Oda T, Berry N, Shinomura T, Asaoka Y, Ogita K, Koide H, Kikkawa U, Kishimoto A, et al.

Prog Brain Res. 1991;89:125-41. Review. No abstract available.

PMID:
1796138
50.

Expression, separation, and assay of protein kinase C subspecies.

Ogita K, Ono Y, Kikkawa U, Nishizuka Y.

Methods Enzymol. 1991;200:228-34. No abstract available.

PMID:
1659653

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