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Items: 1 to 50 of 639

1.

The pathogenetic role of β-cell mitochondria in type 2 diabetes.

Fex M, Nicholas LM, Vishnu N, Medina A, Sharoyko VV, Nicholls DG, Spégel P, Mulder H.

J Endocrinol. 2018 Mar;236(3):R145-R159. doi: 10.1530/JOE-17-0367. Review.

2.

Impact of a five-dimensional framework on R&D productivity at AstraZeneca.

Morgan P, Brown DG, Lennard S, Anderton MJ, Barrett JC, Eriksson U, Fidock M, Hamrén B, Johnson A, March RE, Matcham J, Mettetal J, Nicholls DJ, Platz S, Rees S, Snowden MA, Pangalos MN.

Nat Rev Drug Discov. 2018 Mar;17(3):167-181. doi: 10.1038/nrd.2017.244. Epub 2018 Jan 19. Review.

PMID:
29348681
3.

Characterisation of a major phytoplankton bloom in the River Thames (UK) using flow cytometry and high performance liquid chromatography.

Moorhouse HL, Read DS, McGowan S, Wagner M, Roberts C, Armstrong LK, Nicholls DJE, Wickham HD, Hutchins MG, Bowes MJ.

Sci Total Environ. 2018 May 15;624:366-376. doi: 10.1016/j.scitotenv.2017.12.128. Epub 2017 Dec 16.

PMID:
29258037
4.

Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases.

Connolly NMC, Theurey P, Adam-Vizi V, Bazan NG, Bernardi P, Bolaños JP, Culmsee C, Dawson VL, Deshmukh M, Duchen MR, Düssmann H, Fiskum G, Galindo MF, Hardingham GE, Hardwick JM, Jekabsons MB, Jonas EA, Jordán J, Lipton SA, Manfredi G, Mattson MP, McLaughlin B, Methner A, Murphy AN, Murphy MP, Nicholls DG, Polster BM, Pozzan T, Rizzuto R, Satrústegui J, Slack RS, Swanson RA, Swerdlow RH, Will Y, Ying Z, Joselin A, Gioran A, Moreira Pinho C, Watters O, Salvucci M, Llorente-Folch I, Park DS, Bano D, Ankarcrona M, Pizzo P, Prehn JHM.

Cell Death Differ. 2018 Mar;25(3):542-572. doi: 10.1038/s41418-017-0020-4. Epub 2017 Dec 11. Review.

PMID:
29229998
5.

Instilling hope for a brighter future: A mixed-method mentoring support programme for individuals with and recovered from anorexia nervosa.

Ramjan LM, Fogarty S, Nicholls D, Hay P.

J Clin Nurs. 2018 Mar;27(5-6):e845-e857. doi: 10.1111/jocn.14200. Epub 2018 Jan 11.

PMID:
29193481
6.

A model to teach concomitant patient communication during psychomotor skill development.

Nicholls D, Sweet L, Muller A, Hyett J.

Nurse Educ Today. 2018 Jan;60:121-126. doi: 10.1016/j.nedt.2017.09.004. Epub 2017 Sep 18. Review.

PMID:
29096384
7.

Outcomes of 50 patients entering an adolescent bariatric surgery programme.

White B, Doyle J, Matschull K, Adamo M, Christie D, Nicholls D, Kinra S, Wong ICK, Viner RM.

Arch Dis Child. 2017 Aug 9. pii: archdischild-2017-312670. doi: 10.1136/archdischild-2017-312670. [Epub ahead of print]

PMID:
28794094
8.

Burden of child and adolescent obesity on health services in England.

Viner RM, Kinra S, Nicholls D, Cole T, Kessel A, Christie D, White B, Croker H, Wong ICK, Saxena S.

Arch Dis Child. 2018 Mar;103(3):247-254. doi: 10.1136/archdischild-2017-313009. Epub 2017 Aug 1.

PMID:
28765261
9.

The CEDAR Study: A Longitudinal Study of the Clinical Effects of Conventional DMARDs and Biologic DMARDs in Australian Rheumatology Practice.

Roberts L, Tymms K, de Jager J, Littlejohn G, Griffiths H, Nicholls D, Bird P, Young J, Hill J, Zochling J.

Int J Rheumatol. 2017;2017:1201450. doi: 10.1155/2017/1201450. Epub 2017 May 23.

10.

Cardiopulmonary Exercise Testing and Metabolic Myopathies.

Riley MS, Nicholls DP, Cooper CB.

Ann Am Thorac Soc. 2017 Jul;14(Supplement_1):S129-S139. doi: 10.1513/AnnalsATS.201701-014FR.

PMID:
28590155
11.

Understanding the experience of women admitted to a psychiatric hospital in Sydney with psychosis or mania following childbirth after World War II (1945-1955).

Jefferies D, Duff M, Nicholls D.

Int J Ment Health Nurs. 2018 Apr;27(2):702-711. doi: 10.1111/inm.12357. Epub 2017 Jun 1.

PMID:
28573787
12.

Teaching physiotherapy students to "be content with a body that refuses to hold still".

Macdonald H, Nicholls DA.

Physiother Theory Pract. 2017 Apr;33(4):303-315. doi: 10.1080/09593985.2017.1302027.

PMID:
28443789
13.

Quantifying intracellular rates of glycolytic and oxidative ATP production and consumption using extracellular flux measurements.

Mookerjee SA, Gerencser AA, Nicholls DG, Brand MD.

J Biol Chem. 2017 Apr 28;292(17):7189-7207. doi: 10.1074/jbc.M116.774471. Epub 2017 Mar 7.

PMID:
28270511
14.

Longitudinal study of clinical prognostic factors in patients with early rheumatoid arthritis: the PREDICT study.

Bird P, Nicholls D, Barrett R, de Jager J, Griffiths H, Roberts L, Tymms K, McCloud P, Littlejohn G; OPAL consortium.

Int J Rheum Dis. 2017 Apr;20(4):460-468. doi: 10.1111/1756-185X.13036. Epub 2017 Feb 16.

PMID:
28205333
15.

Objecting: Multiplicity and the practice of physiotherapy.

Setchell J, Nicholls DA, Gibson BE.

Health (London). 2018 Mar;22(2):165-184. doi: 10.1177/1363459316688519. Epub 2017 Jan 23.

PMID:
28111989
16.

Classification of childhood onset eating disorders: A latent class analysis.

Pinhas L, Nicholls D, Crosby RD, Morris A, Lynn RM, Madden S.

Int J Eat Disord. 2017 Jun;50(6):657-664. doi: 10.1002/eat.22666. Epub 2017 Jan 20.

PMID:
28106914
17.

From questions to answers: Examining the role of pediatric surveillance units in eating disorder research.

Katzman DK, Madden S, Nicholls D, Mawjee K, Norris ML.

Int J Eat Disord. 2017 Mar;50(3):259-265. doi: 10.1002/eat.22663. Epub 2017 Jan 17.

PMID:
28093801
18.

Brain mitochondrial calcium transport: Origins of the set-point concept and its application to physiology and pathology.

Nicholls DG.

Neurochem Int. 2017 Oct;109:5-12. doi: 10.1016/j.neuint.2016.12.018. Epub 2017 Jan 3. Review.

PMID:
28057556
19.

The hunt for the molecular mechanism of brown fat thermogenesis.

Nicholls DG.

Biochimie. 2017 Mar;134:9-18. doi: 10.1016/j.biochi.2016.09.003. Epub 2016 Sep 9. Review.

PMID:
27621145
20.

The Pancreatic β-Cell: A Bioenergetic Perspective.

Nicholls DG.

Physiol Rev. 2016 Oct;96(4):1385-447. doi: 10.1152/physrev.00009.2016. Review.

21.

Assessment and treatment of eating disorders in children and adolescents.

Mairs R, Nicholls D.

Arch Dis Child. 2016 Dec;101(12):1168-1175. doi: 10.1136/archdischild-2015-309481. Epub 2016 Jun 28. Review.

PMID:
27381185
22.

Childhood risk factors for lifetime bulimic or compulsive eating by age 30 years in a British national birth cohort.

Nicholls D, Statham R, Costa S, Micali N, Viner RM.

Appetite. 2016 Oct 1;105:266-73. doi: 10.1016/j.appet.2016.05.036. Epub 2016 Jun 2.

PMID:
27263069
23.

Participatory action research for women with anorexia nervosa.

Nicholls D, Fogarty S, Hay P, Ramjan LM.

Nurse Res. 2016 May;23(5):26-30. doi: 10.7748/nr.23.5.26.s6.

PMID:
27188570
24.

Predictors of respiratory instability in neonates undergoing patient ductus arteriosus ligation after the introduction of targeted milrinone treatment.

Ting JY, Resende M, More K, Nicholls D, Weisz DE, El-Khuffash A, Jain A, McNamara PJ.

J Thorac Cardiovasc Surg. 2016 Aug;152(2):498-504. doi: 10.1016/j.jtcvs.2016.03.085. Epub 2016 Apr 14.

PMID:
27174516
25.

A novel regulatory mechanism for the brown-fat uncoupling protein?

Nicholls DG, Rial E.

Nat Struct Mol Biol. 2016 May 4;23(5):364-5. doi: 10.1038/nsmb.3221. No abstract available.

PMID:
27142321
26.

Connectivity: An emerging concept for physiotherapy practice.

Nicholls DA, Atkinson K, Bjorbækmo WS, Gibson BE, Latchem J, Olesen J, Ralls J, Setchell J.

Physiother Theory Pract. 2016;32(3):159-70. doi: 10.3109/09593985.2015.1137665. Epub 2016 Apr 6.

PMID:
27050116
27.

Determining Maximum Glycolytic Capacity Using Extracellular Flux Measurements.

Mookerjee SA, Nicholls DG, Brand MD.

PLoS One. 2016 Mar 31;11(3):e0152016. doi: 10.1371/journal.pone.0152016. eCollection 2016.

28.

Teaching psychomotor skills in the twenty-first century: Revisiting and reviewing instructional approaches through the lens of contemporary literature.

Nicholls D, Sweet L, Muller A, Hyett J.

Med Teach. 2016 Oct;38(10):1056-1063. Epub 2016 Mar 29. Review.

PMID:
27023405
29.

Launching surface plasmon waves via vanishingly small periodic gratings.

Nicholls DP, Oh SH, Johnson TW, Reitich F.

J Opt Soc Am A Opt Image Sci Vis. 2016 Mar;33(3):276-85. doi: 10.1364/JOSAA.33.000276.

PMID:
26974896
30.

Refeeding Low Weight Hospitalized Adolescents With Anorexia Nervosa: A Multicenter Randomized Controlled Trial.

O'Connor G, Nicholls D, Hudson L, Singhal A.

Nutr Clin Pract. 2016 Oct;31(5):681-9. doi: 10.1177/0884533615627267. Epub 2016 Feb 11.

PMID:
26869609
31.

The impact of a dedicated patent ductus arteriosus ligation team on neonatal health-care outcomes.

Resende MH, More K, Nicholls D, Ting J, Jain A, McNamara PJ.

J Perinatol. 2016 Jun;36(6):463-8. doi: 10.1038/jp.2015.213. Epub 2016 Jan 14.

PMID:
26765550
32.

Pharmacodynamics of Ceftolozane plus Tazobactam Studied in an In Vitro Pharmacokinetic Model of Infection.

MacGowan AP, Noel AR, Tomaselli SG, Nicholls D, Bowker KE.

Antimicrob Agents Chemother. 2015 Nov 9;60(1):515-21. doi: 10.1128/AAC.00727-15. Print 2016 Jan.

33.

Systematic review of psychological and social outcomes of adolescents undergoing bariatric surgery, and predictors of success.

White B, Doyle J, Colville S, Nicholls D, Viner RM, Christie D.

Clin Obes. 2015 Dec;5(6):312-24. doi: 10.1111/cob.12119. Epub 2015 Nov 6. Review.

PMID:
26541244
34.

Method of field expansions for vector electromagnetic scattering by layered periodic crossed gratings.

Nicholls DP.

J Opt Soc Am A Opt Image Sci Vis. 2015 May 1;32(5):701-9. doi: 10.1364/JOSAA.32.000701.

PMID:
26366892
35.

Historical perspectives: a snapshot of women admitted to psychiatric facilities with psychosis or mania after childbirth in the late Victorian and inter-war periods.

Jefferies D, Duff M, Burns E, Nicholls D.

J Adv Nurs. 2015 Dec;71(12):2799-810. doi: 10.1111/jan.12761. Epub 2015 Aug 28.

PMID:
26315153
36.

Calcium modulation of exocytosis-linked plasma membrane potential oscillations in INS-1 832/13 cells.

Gerencser AA, Mulder H, Nicholls DG.

Biochem J. 2015 Oct 1;471(1):111-22. doi: 10.1042/BJ20150616. Epub 2015 Aug 4.

PMID:
26243883
37.

Body composition in young female eating-disorder patients with severe weight loss and controls: evidence from the four-component model and evaluation of DXA.

Wells JC, Haroun D, Williams JE, Nicholls D, Darch T, Eaton S, Fewtrell MS.

Eur J Clin Nutr. 2015 Dec;69(12):1330-5. doi: 10.1038/ejcn.2015.111. Epub 2015 Jul 15.

38.

Patients with Rheumatoid Arthritis in the Australian OPAL Cohort Show Significant Improvement in Disease Activity over 5 Years: A Multicenter Observational Study.

Littlejohn G, Roberts L, Bird P, de Jager J, Griffiths H, Nicholls D, Young J, Zochling J, Tymms KE.

J Rheumatol. 2015 Sep;42(9):1603-9. doi: 10.3899/jrheum.141575. Epub 2015 Jul 1.

PMID:
26136482
39.

The value of purpose built mental health facilities: Use of the Ward Atmosphere Scale to gauge the link between milieu and physical environment.

Nicholls D, Kidd K, Threader J, Hungerford C.

Int J Ment Health Nurs. 2015 Aug;24(4):286-94. doi: 10.1111/inm.12138. Epub 2015 May 14.

PMID:
25975388
40.

Characterization of stimulus-secretion coupling in the human pancreatic EndoC-βH1 beta cell line.

Andersson LE, Valtat B, Bagge A, Sharoyko VV, Nicholls DG, Ravassard P, Scharfmann R, Spégel P, Mulder H.

PLoS One. 2015 Mar 24;10(3):e0120879. doi: 10.1371/journal.pone.0120879. eCollection 2015.

41.

Pharmacological characterization of AZD5069, a slowly reversible CXC chemokine receptor 2 antagonist.

Nicholls DJ, Wiley K, Dainty I, MacIntosh F, Phillips C, Gaw A, Mårdh CK.

J Pharmacol Exp Ther. 2015 May;353(2):340-50. doi: 10.1124/jpet.114.221358. Epub 2015 Mar 3.

42.

Discovery and evaluation of a novel monocyclic series of CXCR2 antagonists.

Austin RP, Bennion C, Bonnert RV, Cheema L, Cook AR, Cox RJ, Ebden MR, Gaw A, Grime K, Meghani P, Nicholls D, Phillips C, Smith N, Steele J, Stonehouse JP.

Bioorg Med Chem Lett. 2015 Apr 1;25(7):1616-20. doi: 10.1016/j.bmcl.2015.01.067. Epub 2015 Feb 3.

PMID:
25708618
43.

Re/creating entrepreneurs of the self: discourses of worker and employee 'value' and current vocational rehabilitation practices.

Fadyl J, McPherson K, Nicholls D.

Sociol Health Illn. 2015 May;37(4):506-21. doi: 10.1111/1467-9566.12212. Epub 2015 Jan 7.

PMID:
25565115
44.

The contributions of respiration and glycolysis to extracellular acid production.

Mookerjee SA, Goncalves RL, Gerencser AA, Nicholls DG, Brand MD.

Biochim Biophys Acta. 2015 Feb;1847(2):171-81. doi: 10.1016/j.bbabio.2014.10.005. Epub 2014 Oct 27.

45.

Use of potentiometric fluorophores in the measurement of mitochondrial reactive oxygen species.

Polster BM, Nicholls DG, Ge SX, Roelofs BA.

Methods Enzymol. 2014;547:225-50. doi: 10.1016/B978-0-12-801415-8.00013-8.

46.

The key to using a learning or skill acquisition plan.

Nicholls D, Sweet L, Westerway SC, Gibbins A.

Australas J Ultrasound Med. 2014 Nov;17(4):141-145. doi: 10.1002/j.2205-0140.2014.tb00235.x. Epub 2015 Dec 31.

47.

The 'mitoflash' probe cpYFP does not respond to superoxide.

Schwarzländer M, Wagner S, Ermakova YG, Belousov VV, Radi R, Beckman JS, Buettner GR, Demaurex N, Duchen MR, Forman HJ, Fricker MD, Gems D, Halestrap AP, Halliwell B, Jakob U, Johnston IG, Jones NS, Logan DC, Morgan B, Müller FL, Nicholls DG, Remington SJ, Schumacker PT, Winterbourn CC, Sweetlove LJ, Meyer AJ, Dick TP, Murphy MP.

Nature. 2014 Oct 23;514(7523):E12-4. doi: 10.1038/nature13858. No abstract available.

48.

Mitochondrial bioenergetics and neuronal survival modelled in primary neuronal culture and isolated nerve terminals.

Nicholls DG, Brand MD, Gerencser AA.

J Bioenerg Biomembr. 2015 Apr;47(1-2):63-74. doi: 10.1007/s10863-014-9573-9. Epub 2014 Aug 30. Review.

PMID:
25172197
49.

Aural rehabilitation through music workshops for cochlear implant users.

van Besouw RM, Nicholls DR, Oliver BR, Hodkinson SM, Grasmeder ML.

J Am Acad Audiol. 2014 Apr;25(4):311-23. doi: 10.3766/jaaa.25.4.3.

PMID:
25126679
50.

Fast high-order perturbation of surfaces methods for simulation of multilayer plasmonic devices and metamaterials.

Nicholls DP, Reitich F, Johnson TW, Oh SH.

J Opt Soc Am A Opt Image Sci Vis. 2014 Aug 1;31(8):1820-31. doi: 10.1364/JOSAA.31.001820.

PMID:
25121539

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