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A postmortem analysis of NMDA ionotropic and group 1 metabotropic glutamate receptors in the nucleus accumbens in schizophrenia.

Lum JS, Millard SJ, Huang XF, Ooi L, Newell KA.

J Psychiatry Neurosci. 2018 Mar;43(2):102-110.


Biomarkers of operational tolerance following kidney transplantation - The immune tolerance network studies of spontaneously tolerant kidney transplant recipients.

Newell KA, Adams AB, Turka LA.

Hum Immunol. 2018 Feb 12. pii: S0198-8859(18)30045-4. doi: 10.1016/j.humimm.2018.02.007. [Epub ahead of print] Review.


Effects of short- and long-term aripiprazole treatment on Group I mGluRs in the nucleus accumbens: Comparison with haloperidol.

Lum JS, Pan B, Deng C, Huang XF, Ooi L, Newell KA.

Psychiatry Res. 2017 Nov 21;260:152-157. doi: 10.1016/j.psychres.2017.11.048. [Epub ahead of print]


Reply to Christakoudi and Hernandez-Fuentes: We agree-Let's move on.

Asare A, Kanaparthi S, Lim N, Newell KA, Turka LA.

Am J Transplant. 2018 Jan;18(1):273. doi: 10.1111/ajt.14569. Epub 2017 Nov 18. No abstract available.


A postmortem analysis of NMDA ionotropic and group 1 metabotropic glutamate receptors in the nucleus accumbens in schizophrenia.

Lum JS, Millard SJ, Huang XF, Ooi L, Newell KA.

J Psychiatry Neurosci. 2017 Oct 6;42(6):170077. doi: 10.1503/jpn.170077. [Epub ahead of print]


Dietary teasaponin ameliorates alteration of gut microbiota and cognitive decline in diet-induced obese mice.

Wang S, Huang XF, Zhang P, Newell KA, Wang H, Zheng K, Yu Y.

Sci Rep. 2017 Sep 22;7(1):12203. doi: 10.1038/s41598-017-12156-2.


Luteolin, a natural flavonoid, inhibits methylglyoxal induced apoptosis via the mTOR/4E-BP1 signaling pathway.

Liu Y, Huang J, Zheng X, Yang X, Ding Y, Fang T, Zhang Y, Wang S, Zhang X, Luo X, Guo A, Newell KA, Yu Y, Huang XF.

Sci Rep. 2017 Aug 11;7(1):7877. doi: 10.1038/s41598-017-08204-6.


The effects of maternal antidepressant use on offspring behaviour and brain development: Implications for risk of neurodevelopmental disorders.

Millard SJ, Weston-Green K, Newell KA.

Neurosci Biobehav Rev. 2017 Sep;80:743-765. doi: 10.1016/j.neubiorev.2017.06.008. Epub 2017 Jun 16. Review.


Alloimmunity But Not Viral Immunity Promotes Allograft Loss in a Mouse Model of Polyomavirus-Associated Allograft Injury.

Kim SC, Wang J, Dong Y, Mathews DV, Albrecht JA, Breeden CP, Farris AB, Lukacher AE, Ford ML, Newell KA, Adams AB.

Transplant Direct. 2017 May 12;3(6):e161. doi: 10.1097/TXD.0000000000000677. eCollection 2017 Jun.


Lessons Learned: Early Termination of a Randomized Trial of Calcineurin Inhibitor and Corticosteroid Avoidance Using Belatacept.

Newell KA, Mehta AK, Larsen CP, Stock PG, Farris AB, Mehta SG, Ikle D, Armstrong B, Morrison Y, Bridges N, Robien M, Mannon RB.

Am J Transplant. 2017 Oct;17(10):2712-2719. doi: 10.1111/ajt.14377. Epub 2017 Jul 3.


Belatacept Combined With Transient Calcineurin Inhibitor Therapy Prevents Rejection and Promotes Improved Long-Term Renal Allograft Function.

Adams AB, Goldstein J, Garrett C, Zhang R, Patzer RE, Newell KA, Turgeon NA, Chami AS, Guasch A, Kirk AD, Pastan SO, Pearson TC, Larsen CP.

Am J Transplant. 2017 Nov;17(11):2922-2936. doi: 10.1111/ajt.14353. Epub 2017 Jul 3.


The Living Donor Collective: A Scientific Registry for Living Donors.

Kasiske BL, Asrani SK, Dew MA, Henderson ML, Henrich C, Humar A, Israni AK, Lentine KL, Matas AJ, Newell KA, LaPointe Rudow D, Massie AB, Snyder JJ, Taler SJ, Trotter JF, Waterman AD; Living Donor Collective participants.

Am J Transplant. 2017 Dec;17(12):3040-3048. doi: 10.1111/ajt.14365. Epub 2017 Jun 22.


Effects of common GRM5 genetic variants on cognition, hippocampal volume and mGluR5 protein levels in schizophrenia.

Matosin N, Newell KA, Quidé Y, Andrews JL, Teroganova N, Green MJ, Fernandez F.

Brain Imaging Behav. 2017 Apr 13. doi: 10.1007/s11682-017-9712-0. [Epub ahead of print]


B Cell Receptor Genes Associated With Tolerance Identify a Cohort of Immunosuppressed Patients With Improved Renal Allograft Graft Function.

Asare A, Kanaparthi S, Lim N, Phippard D, Vincenti F, Friedewald J, Pavlakis M, Poggio E, Heeger P, Mannon R, Burrell BE, Morrison Y, Bridges N, Sanz I, Chandraker A, Newell KA, Turka LA.

Am J Transplant. 2017 Oct;17(10):2627-2639. doi: 10.1111/ajt.14283. Epub 2017 May 2.


A composite score associated with spontaneous operational tolerance in kidney transplant recipients.

Danger R, Chesneau M, Paul C, Guérif P, Durand M, Newell KA, Kanaparthi S, Turka LA, Soulillou JP, Houlgatte R, Giral M, Ramstein G, Brouard S.

Kidney Int. 2017 Jun;91(6):1473-1481. doi: 10.1016/j.kint.2016.12.020. Epub 2017 Feb 24.


Alterations of ubiquitin related proteins in the pathology and development of schizophrenia: Evidence from human and animal studies.

Andrews JL, Goodfellow FJ, Matosin N, Snelling MK, Newell KA, Huang XF, Fernandez-Enright F.

J Psychiatr Res. 2017 Jul;90:31-39. doi: 10.1016/j.jpsychires.2017.01.009. Epub 2017 Jan 18.


Integrating APOL1 Gene Variants Into Renal Transplantation: Considerations Arising From the American Society of Transplantation Expert Conference.

Newell KA, Formica RN, Gill JS, Schold JD, Allan JS, Covington SH, Wiseman AC, Chandraker A.

Am J Transplant. 2017 Apr;17(4):901-911. doi: 10.1111/ajt.14173. Epub 2017 Feb 2.


Neurodevelopmental Expression Profile of Dimeric and Monomeric Group 1 mGluRs: Relevance to Schizophrenia Pathogenesis and Treatment.

Lum JS, Fernandez F, Matosin N, Andrews JL, Huang XF, Ooi L, Newell KA.

Sci Rep. 2016 Oct 10;6:34391. doi: 10.1038/srep34391.


Towards Improving the Transfer of Care of Kidney Transplant Recipients.

Gill JS, Wright AJ, Delmonico FL, Newell KA.

Am J Transplant. 2017 Jan;17(1):54-59. doi: 10.1111/ajt.13997. Epub 2016 Sep 6.


Molecular evidence of synaptic pathology in the CA1 region in schizophrenia.

Matosin N, Fernandez-Enright F, Lum JS, Engel M, Andrews JL, Gassen NC, Wagner KV, Schmidt MV, Newell KA.

NPJ Schizophr. 2016 Jun 29;2:16022. doi: 10.1038/npjschz.2016.22. eCollection 2016.


Transplantation tolerance: Coming of age.

Adams AB, Newell KA.

Hepatology. 2016 Aug;64(2):347-9. doi: 10.1002/hep.28553. Epub 2016 May 17. No abstract available.


Erratum to: mGluR2/3 agonist LY379268 rescues NMDA and GABAA receptor level deficits induced in a two-hit mouse model of schizophrenia.

Engel M, Snikeris P, Matosin N, Newell KA, Huang XF, Frank E.

Psychopharmacology (Berl). 2016 Apr;233(8):1537. doi: 10.1007/s00213-016-4261-6. No abstract available.


mGluR2/3 agonist LY379268 rescues NMDA and GABAA receptor level deficits induced in a two-hit mouse model of schizophrenia.

Engel M, Snikeris P, Matosin N, Newell KA, Huang XF, Frank E.

Psychopharmacology (Berl). 2016 Apr;233(8):1349-59. doi: 10.1007/s00213-016-4230-0. Epub 2016 Feb 10. Erratum in: Psychopharmacology (Berl). 2016 Apr;233(8):1537.


What Is the Price of Altruism?

Formica RN Jr, Newell KA.

Am J Transplant. 2016 Mar;16(3):741-2. doi: 10.1111/ajt.13590. Epub 2016 Feb 4. No abstract available.


Engaging Living Kidney Donors in a New Paradigm of Postdonation Care.

Newell KA, Formica RN, Gill JS.

Am J Transplant. 2016 Jan;16(1):29-32. doi: 10.1111/ajt.13524. Epub 2015 Dec 7.


Possibility of a sex-specific role for a genetic variant in FRMPD4 in schizophrenia, but not cognitive function.

Matosin N, Green MJ, Andrews JL, Newell KA, Fernandez-Enright F.

Neuroreport. 2016 Jan 6;27(1):33-8. doi: 10.1097/WNR.0000000000000491.


Longitudinal studies of a B cell-derived signature of tolerance in renal transplant recipients.

Newell KA, Asare A, Sanz I, Wei C, Rosenberg A, Gao Z, Kanaparthi S, Asare S, Lim N, Stahly M, Howell M, Knechtle S, Kirk A, Marks WH, Kawai T, Spitzer T, Tolkoff-Rubin N, Sykes M, Sachs DH, Cosimi AB, Burlingham WJ, Phippard D, Turka LA.

Am J Transplant. 2015 Nov;15(11):2908-20. doi: 10.1111/ajt.13480. Epub 2015 Oct 13.


Shifting towards a model of mGluR5 dysregulation in schizophrenia: Consequences for future schizophrenia treatment.

Matosin N, Fernandez-Enright F, Lum JS, Newell KA.

Neuropharmacology. 2017 Mar 15;115:73-91. doi: 10.1016/j.neuropharm.2015.08.003. Epub 2015 Sep 6. Review.


Preventing T cell rejection of pig xenografts.

Higginbotham L, Ford ML, Newell KA, Adams AB.

Int J Surg. 2015 Nov;23(Pt B):285-290. doi: 10.1016/j.ijsu.2015.07.722. Epub 2015 Aug 22. Review.


Interferon Gamma ELISPOT Testing as a Risk-Stratifying Biomarker for Kidney Transplant Injury: Results From the CTOT-01 Multicenter Study.

Hricik DE, Augustine J, Nickerson P, Formica RN, Poggio ED, Rush D, Newell KA, Goebel J, Gibson IW, Fairchild RL, Spain K, Iklé D, Bridges ND, Heeger PS; CTOT-01 consortium.

Am J Transplant. 2015 Dec;15(12):3166-73. doi: 10.1111/ajt.13401. Epub 2015 Jul 30.


Tolerance signatures in transplant recipients.

Newell KA, Turka LA.

Curr Opin Organ Transplant. 2015 Aug;20(4):400-5. doi: 10.1097/MOT.0000000000000207. Review.


Alterations of p75 neurotrophin receptor and Myelin transcription factor 1 in the hippocampus of perinatal phencyclidine treated rats.

Andrews JL, Newell KA, Matosin N, Huang XF, Fernandez-Enright F.

Prog Neuropsychopharmacol Biol Psychiatry. 2015 Dec 3;63:91-7. doi: 10.1016/j.pnpbp.2015.06.003. Epub 2015 Jun 10.


Metabotropic glutamate receptor 5, and its trafficking molecules Norbin and Tamalin, are increased in the CA1 hippocampal region of subjects with schizophrenia.

Matosin N, Fernandez-Enright F, Lum JS, Andrews JL, Engel M, Huang XF, Newell KA.

Schizophr Res. 2015 Aug;166(1-3):212-8. doi: 10.1016/j.schres.2015.05.001. Epub 2015 Jun 2.


Pre-transplant antibody screening and anti-CD154 costimulation blockade promote long-term xenograft survival in a pig-to-primate kidney transplant model.

Higginbotham L, Mathews D, Breeden CA, Song M, Farris AB 3rd, Larsen CP, Ford ML, Lutz AJ, Tector M, Newell KA, Tector AJ, Adams AB.

Xenotransplantation. 2015 May-Jun;22(3):221-30. doi: 10.1111/xen.12166. Epub 2015 Apr 3.


Alterations of mGluR5 and its endogenous regulators Norbin, Tamalin and Preso1 in schizophrenia: towards a model of mGluR5 dysregulation.

Matosin N, Fernandez-Enright F, Fung SJ, Lum JS, Engel M, Andrews JL, Huang XF, Weickert CS, Newell KA.

Acta Neuropathol. 2015 Jul;130(1):119-29. doi: 10.1007/s00401-015-1411-6. Epub 2015 Mar 17.


Evaluation of human and non-human primate antibody binding to pig cells lacking GGTA1/CMAH/β4GalNT2 genes.

Estrada JL, Martens G, Li P, Adams A, Newell KA, Ford ML, Butler JR, Sidner R, Tector M, Tector J.

Xenotransplantation. 2015 May-Jun;22(3):194-202. doi: 10.1111/xen.12161. Epub 2015 Mar 1.


A common gene signature across multiple studies relate biomarkers and functional regulation in tolerance to renal allograft.

Baron D, Ramstein G, Chesneau M, Echasseriau Y, Pallier A, Paul C, Degauque N, Hernandez-Fuentes MP, Sanchez-Fueyo A, Newell KA, Giral M, Soulillou JP, Houlgatte R, Brouard S.

Kidney Int. 2015 May;87(5):984-95. doi: 10.1038/ki.2014.395. Epub 2015 Jan 28.


GluN2B protein deficits in the left, but not the right, hippocampus in schizophrenia.

Geddes AE, Huang XF, Newell KA.

BMC Psychiatry. 2014 Oct 8;14:274. doi: 10.1186/s12888-014-0274-z.


Negativity towards negative results: a discussion of the disconnect between scientific worth and scientific culture.

Matosin N, Frank E, Engel M, Lum JS, Newell KA.

Dis Model Mech. 2014 Feb;7(2):171-3. doi: 10.1242/dmm.015123.


Novel implications of Lingo-1 and its signaling partners in schizophrenia.

Fernandez-Enright F, Andrews JL, Newell KA, Pantelis C, Huang XF.

Transl Psychiatry. 2014 Jan 21;4:e348. doi: 10.1038/tp.2013.121.


Metabotropic glutamate receptor 5 in schizophrenia: emerging evidence for the development of antipsychotic drugs.

Newell KA.

Future Med Chem. 2013 Sep;5(13):1471-4. doi: 10.4155/fmc.13.137. No abstract available.


Multicenter validation of urinary CXCL9 as a risk-stratifying biomarker for kidney transplant injury.

Hricik DE, Nickerson P, Formica RN, Poggio ED, Rush D, Newell KA, Goebel J, Gibson IW, Fairchild RL, Riggs M, Spain K, Ikle D, Bridges ND, Heeger PS; CTOT-01 consortium.

Am J Transplant. 2013 Oct;13(10):2634-44. doi: 10.1111/ajt.12426. Epub 2013 Aug 22.


A neuregulin 1 transmembrane domain mutation causes imbalanced glutamatergic and dopaminergic receptor expression in mice.

Newell KA, Karl T, Huang XF.

Neuroscience. 2013 Sep 17;248:670-80. doi: 10.1016/j.neuroscience.2013.06.037. Epub 2013 Jun 27.


Metabotropic glutamate receptor 5 binding and protein expression in schizophrenia and following antipsychotic drug treatment.

Matosin N, Frank E, Deng C, Huang XF, Newell KA.

Schizophr Res. 2013 May;146(1-3):170-6. doi: 10.1016/j.schres.2013.01.018. Epub 2013 Feb 23.


Metabotropic glutamate receptor 5 in the pathology and treatment of schizophrenia.

Matosin N, Newell KA.

Neurosci Biobehav Rev. 2013 Mar;37(3):256-68. doi: 10.1016/j.neubiorev.2012.12.005. Epub 2012 Dec 17. Review.


Molecular evidence of N-methyl-D-aspartate receptor hypofunction in schizophrenia.

Weickert CS, Fung SJ, Catts VS, Schofield PR, Allen KM, Moore LT, Newell KA, Pellen D, Huang XF, Catts SV, Weickert TW.

Mol Psychiatry. 2013 Nov;18(11):1185-92. doi: 10.1038/mp.2012.137. Epub 2012 Oct 16.


Adaptive immunity rather than viral cytopathology mediates polyomavirus-associated nephropathy in mice.

Albrecht JA, Dong Y, Wang J, Breeden C, Farris AB 3rd, Lukacher AE, Newell KA.

Am J Transplant. 2012 Jun;12(6):1419-28. doi: 10.1111/j.1600-6143.2012.04005.x. Epub 2012 Mar 15.


Donor-specific indirect pathway analysis reveals a B-cell-independent signature which reflects outcomes in kidney transplant recipients.

Haynes LD, Jankowska-Gan E, Sheka A, Keller MR, Hernandez-Fuentes MP, Lechler RI, Seyfert-Margolis V, Turka LA, Newell KA, Burlingham WJ.

Am J Transplant. 2012 Mar;12(3):640-8. doi: 10.1111/j.1600-6143.2011.03869.x. Epub 2011 Dec 7.

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