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Items: 23

1.

Comparison of hepatic NRF2 and AHR binding in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) treated mice demonstrates NRF2-independent PKM2 induction.

Nault R, Doskey CM, Fader KA, Rockwell CE, Zacharewski TR.

Mol Pharmacol. 2018 May 11. pii: mol.118.112144. doi: 10.1124/mol.118.112144. [Epub ahead of print]

2.

2,3,7,8-Tetrachlorodibenzo-p-dioxin dose-dependently increases bone mass and decreases marrow adiposity in juvenile mice.

Fader KA, Nault R, Raehtz S, McCabe LR, Zacharewski TR.

Toxicol Appl Pharmacol. 2018 Jun 1;348:85-98. doi: 10.1016/j.taap.2018.04.013. Epub 2018 Apr 16.

PMID:
29673856
3.

Corrigendum to "Convergence of hepcidin deficiency, systemic iron overloading, heme accumulation, and REV-ERBα/β activation in aryl hydrocarbon receptor-elicited hepatotoxicity" [Toxicol. Appl. Pharmacol. 321 (2017) 1-17].

Fader KA, Nault R, Kirby MP, Markous G, Matthews J, Zacharewski TR.

Toxicol Appl Pharmacol. 2018 Apr 1;344:74. doi: 10.1016/j.taap.2018.03.001. Epub 2018 Mar 2. No abstract available.

PMID:
29501526
4.

Disseminated cerebral toxoplasmosis in a patient with chronic lymphocytic leukemia.

Xu J, Nault RJ, Maldonado-Naranjo A, Frizon LA, John K, Holman K, Nagel SJ.

J Clin Neurosci. 2018 Apr;50:127-128. doi: 10.1016/j.jocn.2018.01.057. Epub 2018 Feb 7.

PMID:
29428267
5.

Loss of liver-specific and sexually dimorphic gene expression by aryl hydrocarbon receptor activation in C57BL/6 mice.

Nault R, Fader KA, Harkema JR, Zacharewski T.

PLoS One. 2017 Sep 18;12(9):e0184842. doi: 10.1371/journal.pone.0184842. eCollection 2017.

6.

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-elicited effects on bile acid homeostasis: Alterations in biosynthesis, enterohepatic circulation, and microbial metabolism.

Fader KA, Nault R, Zhang C, Kumagai K, Harkema JR, Zacharewski TR.

Sci Rep. 2017 Jul 19;7(1):5921. doi: 10.1038/s41598-017-05656-8.

7.

Lipidomic Evaluation of Aryl Hydrocarbon Receptor-Mediated Hepatic Steatosis in Male and Female Mice Elicited by 2,3,7,8-Tetrachlorodibenzo-p-dioxin.

Nault R, Fader KA, Lydic TA, Zacharewski TR.

Chem Res Toxicol. 2017 Apr 17;30(4):1060-1075. doi: 10.1021/acs.chemrestox.6b00430. Epub 2017 Mar 20.

8.

Convergence of hepcidin deficiency, systemic iron overloading, heme accumulation, and REV-ERBα/β activation in aryl hydrocarbon receptor-elicited hepatotoxicity.

Fader KA, Nault R, Kirby MP, Markous G, Matthews J, Zacharewski TR.

Toxicol Appl Pharmacol. 2017 Apr 15;321:1-17. doi: 10.1016/j.taap.2017.02.006. Epub 2017 Feb 16. Erratum in: Toxicol Appl Pharmacol. 2018 Mar 1;:.

9.

Comparative analysis of TCDD-induced AhR-mediated gene expression in human, mouse and rat primary B cells.

Kovalova N, Nault R, Crawford R, Zacharewski TR, Kaminski NE.

Toxicol Appl Pharmacol. 2017 Feb 1;316:95-106. doi: 10.1016/j.taap.2016.11.009. Epub 2016 Nov 30.

10.

From the Cover: Coagulation-Driven Hepatic Fibrosis Requires Protease Activated Receptor-1 (PAR-1) in a Mouse Model of TCDD-Elicited Steatohepatitis.

Nault R, Fader KA, Kopec AK, Harkema JR, Zacharewski TR, Luyendyk JP.

Toxicol Sci. 2016 Dec;154(2):381-391. Epub 2016 Sep 9.

11.

Dose-Dependent Metabolic Reprogramming and Differential Gene Expression in TCDD-Elicited Hepatic Fibrosis.

Nault R, Fader KA, Ammendolia DA, Dornbos P, Potter D, Sharratt B, Kumagai K, Harkema JR, Lunt SY, Matthews J, Zacharewski T.

Toxicol Sci. 2016 Dec;154(2):253-266. Epub 2016 Aug 25.

12.

Fibrin deposition following bile duct injury limits fibrosis through an αMβ2-dependent mechanism.

Joshi N, Kopec AK, Ray JL, Cline-Fedewa H, Nawabi A, Schmitt T, Nault R, Zacharewski TR, Rockwell CE, Flick MJ, Luyendyk JP.

Blood. 2016 Jun 2;127(22):2751-62. doi: 10.1182/blood-2015-09-670703. Epub 2016 Feb 26.

13.

Pyruvate Kinase Isoform Switching and Hepatic Metabolic Reprogramming by the Environmental Contaminant 2,3,7,8-Tetrachlorodibenzo-p-Dioxin.

Nault R, Fader KA, Kirby MP, Ahmed S, Matthews J, Jones AD, Lunt SY, Zacharewski TR.

Toxicol Sci. 2016 Feb;149(2):358-71. doi: 10.1093/toxsci/kfv245. Epub 2015 Nov 17.

14.

2,3,7,8-Tetrachlorodibenzo-p-Dioxin Alters Lipid Metabolism and Depletes Immune Cell Populations in the Jejunum of C57BL/6 Mice.

Fader KA, Nault R, Ammendolia DA, Harkema JR, Williams KJ, Crawford RB, Kaminski NE, Potter D, Sharratt B, Zacharewski TR.

Toxicol Sci. 2015 Dec;148(2):567-80. doi: 10.1093/toxsci/kfv206. Epub 2015 Sep 16.

15.

Ozone-Induced Type 2 Immunity in Nasal Airways. Development and Lymphoid Cell Dependence in Mice.

Ong CB, Kumagai K, Brooks PT, Brandenberger C, Lewandowski RP, Jackson-Humbles DN, Nault R, Zacharewski TR, Wagner JG, Harkema JR.

Am J Respir Cell Mol Biol. 2016 Mar;54(3):331-40. doi: 10.1165/rcmb.2015-0165OC.

PMID:
26203683
16.

RNA-Seq versus oligonucleotide array assessment of dose-dependent TCDD-elicited hepatic gene expression in mice.

Nault R, Fader KA, Zacharewski T.

BMC Genomics. 2015 May 10;16:373. doi: 10.1186/s12864-015-1527-z.

17.

Development of a computational high-throughput tool for the quantitative examination of dose-dependent histological features.

Nault R, Colbry D, Brandenberger C, Harkema JR, Zacharewski TR.

Toxicol Pathol. 2015 Apr;43(3):366-75. doi: 10.1177/0192623314544379. Epub 2014 Oct 1.

18.

Comparisons of differential gene expression elicited by TCDD, PCB126, βNF, or ICZ in mouse hepatoma Hepa1c1c7 cells and C57BL/6 mouse liver.

Nault R, Forgacs AL, Dere E, Zacharewski TR.

Toxicol Lett. 2013 Oct 23;223(1):52-9. doi: 10.1016/j.toxlet.2013.08.013. Epub 2013 Aug 29.

19.

Toxicogenomic evaluation of long-term hepatic effects of TCDD in immature, ovariectomized C57BL/6 mice.

Kopec AK, Boverhof DR, Nault R, Harkema JR, Tashiro C, Potter D, Sharratt B, Chittim B, Zacharewski TR.

Toxicol Sci. 2013 Oct;135(2):465-75. doi: 10.1093/toxsci/kft156. Epub 2013 Jul 17.

20.

Assessment of energetic costs of AhR activation by β-naphthoflavone in rainbow trout (Oncorhynchus mykiss) hepatocytes using metabolic flux analysis.

Nault R, Abdul-Fattah H, Mironov GG, Berezovski MV, Moon TW.

Toxicol Appl Pharmacol. 2013 Aug 15;271(1):86-94. doi: 10.1016/j.taap.2013.04.017. Epub 2013 Apr 29.

PMID:
23639520
21.

Comparison of TCDD-elicited genome-wide hepatic gene expression in Sprague-Dawley rats and C57BL/6 mice.

Nault R, Kim S, Zacharewski TR.

Toxicol Appl Pharmacol. 2013 Mar 1;267(2):184-91. doi: 10.1016/j.taap.2012.11.028. Epub 2012 Dec 11.

22.

Effects of polychlorinated biphenyls on whole animal energy mobilization and hepatic cellular respiration in rainbow trout, Oncorhynchus mykiss.

Nault R, Al-Hameedi S, Moon TW.

Chemosphere. 2012 May;87(9):1057-62. doi: 10.1016/j.chemosphere.2012.02.012. Epub 2012 Mar 10.

PMID:
22410624
23.

Variation in cadmium content of caribou tissues from northern Québec.

Crête M, Nault R, Walsh P, Benedetti JL, Lefebvre MA, Weber JP, Gagnon J.

Sci Total Environ. 1989 May 15;80(2-3):103-12.

PMID:
2569761

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