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Items: 1 to 50 of 356

1.

Modeling the Subclonal Evolution of Cancer Cell Populations.

Chowell D, Napier J, Gupta R, Anderson KS, Maley CC, Sayres MAW.

Cancer Res. 2018 Feb 1;78(3):830-839. doi: 10.1158/0008-5472.CAN-17-1229. Epub 2017 Nov 29.

PMID:
29187407
2.

Aflibercept treatment for neovascular AMD beyond the first year: consensus recommendations by a UK expert roundtable panel, 2017 update.

Patel PJ, Devonport H, Sivaprasad S, Ross AH, Walters G, Gale RP, Lotery AJ, Mahmood S, Talks JS, Napier J.

Clin Ophthalmol. 2017 Nov 6;11:1957-1966. doi: 10.2147/OPTH.S145732. eCollection 2017.

3.

A transatlantic perspective on 20 emerging issues in biological engineering.

Wintle BC, Boehm CR, Rhodes C, Molloy JC, Millett P, Adam L, Breitling R, Carlson R, Casagrande R, Dando M, Doubleday R, Drexler E, Edwards B, Ellis T, Evans NG, Hammond R, Haseloff J, Kahl L, Kuiken T, Lichman BR, Matthewman CA, Napier JA, ÓhÉigeartaigh SS, Patron NJ, Perello E, Shapira P, Tait J, Takano E, Sutherland WJ.

Elife. 2017 Nov 14;6. pii: e30247. doi: 10.7554/eLife.30247.

4.

Differential support for female supervisors among men and women.

Vial AC, Brescoll VL, Napier JL, Dovidio JF, Tyler TR.

J Appl Psychol. 2018 Feb;103(2):215-227. doi: 10.1037/apl0000258. Epub 2017 Sep 21.

PMID:
28933911
5.

Tailoring seed oil composition in the real world: optimising omega-3 long chain polyunsaturated fatty acid accumulation in transgenic Camelina sativa.

Usher S, Han L, Haslam RP, Michaelson LV, Sturtevant D, Aziz M, Chapman KD, Sayanova O, Napier JA.

Sci Rep. 2017 Jul 26;7(1):6570. doi: 10.1038/s41598-017-06838-0.

6.

Modulation of lipid biosynthesis by stress in diatoms.

Sayanova O, Mimouni V, Ulmann L, Morant-Manceau A, Pasquet V, Schoefs B, Napier JA.

Philos Trans R Soc Lond B Biol Sci. 2017 Sep 5;372(1728). pii: 20160407. doi: 10.1098/rstb.2016.0407. Review.

7.

Action on diabetic macular oedema: achieving optimal patient management in treating visual impairment due to diabetic eye disease.

Gale R, Scanlon PH, Evans M, Ghanchi F, Yang Y, Silvestri G, Freeman M, Maisey A, Napier J.

Eye (Lond). 2017 May;31(S1):S1-S20. doi: 10.1038/eye.2017.53.

8.

Erratum to: Replacement of Marine Fish Oil with de novo Omega-3 Oils from Transgenic Camelina sativa in Feeds for Gilthead Sea Bream (Sparus aurata L.).

Betancor MB, Sprague M, Montero D, Usher S, Sayanova O, Campbell PJ, Napier JA, Caballero MJ, Izquierdo M, Tocher DR.

Lipids. 2017 May;52(5):463. doi: 10.1007/s11745-017-4248-z. No abstract available.

PMID:
28421424
9.

An oil containing EPA and DHA from transgenic Camelina sativa to replace marine fish oil in feeds for Atlantic salmon (Salmo salar L.): Effects on intestinal transcriptome, histology, tissue fatty acid profiles and plasma biochemistry.

Betancor MB, Li K, Sprague M, Bardal T, Sayanova O, Usher S, Han L, Måsøval K, Torrissen O, Napier JA, Tocher DR, Olsen RE.

PLoS One. 2017 Apr 12;12(4):e0175415. doi: 10.1371/journal.pone.0175415. eCollection 2017.

10.

Chlamydomonas carries out fatty acid β-oxidation in ancestral peroxisomes using a bona fide acyl-CoA oxidase.

Kong F, Liang Y, Légeret B, Beyly-Adriano A, Blangy S, Haslam RP, Napier JA, Beisson F, Peltier G, Li-Beisson Y.

Plant J. 2017 Apr;90(2):358-371. doi: 10.1111/tpj.13498. Epub 2017 Mar 20.

PMID:
28142200
11.

Regulation of miR-29b-1/a transcription and identification of target mRNAs in CHO-K1 cells.

Muluhngwi P, Richardson K, Napier J, Rouchka EC, Mott JL, Klinge CM.

Mol Cell Endocrinol. 2017 Mar 15;444:38-47. doi: 10.1016/j.mce.2017.01.044. Epub 2017 Jan 28.

PMID:
28137615
12.

Tailoring the composition of novel wax esters in the seeds of transgenic Camelina sativa through systematic metabolic engineering.

Ruiz-Lopez N, Broughton R, Usher S, Salas JJ, Haslam RP, Napier JA, Beaudoin F.

Plant Biotechnol J. 2017 Jul;15(7):837-849. doi: 10.1111/pbi.12679. Epub 2017 Feb 2.

13.

Tamoxifen differentially regulates miR-29b-1 and miR-29a expression depending on endocrine-sensitivity in breast cancer cells.

Muluhngwi P, Krishna A, Vittitow SL, Napier JT, Richardson KM, Ellis M, Mott JL, Klinge CM.

Cancer Lett. 2017 Mar 1;388:230-238. doi: 10.1016/j.canlet.2016.12.007. Epub 2016 Dec 13.

PMID:
27986463
14.

Metabolome Analysis Reveals Betaine Lipids as Major Source for Triglyceride Formation, and the Accumulation of Sedoheptulose during Nitrogen-Starvation of Phaeodactylum tricornutum.

Popko J, Herrfurth C, Feussner K, Ischebeck T, Iven T, Haslam R, Hamilton M, Sayanova O, Napier J, Khozin-Goldberg I, Feussner I.

PLoS One. 2016 Oct 13;11(10):e0164673. doi: 10.1371/journal.pone.0164673. eCollection 2016.

15.

Sunflower HaGPAT9-1 is the predominant GPAT during seed development.

Payá-Milans M, Aznar-Moreno JA, Balbuena TS, Haslam RP, Gidda SK, Pérez-Hormaeche J, Mullen RT, Thelen JJ, Napier JA, Salas JJ, Garcés R, Martínez-Force E, Venegas-Calerón M.

Plant Sci. 2016 Nov;252:42-52. doi: 10.1016/j.plantsci.2016.07.002. Epub 2016 Jul 9.

PMID:
27717477
16.

Replacement of Marine Fish Oil with de novo Omega-3 Oils from Transgenic Camelina sativa in Feeds for Gilthead Sea Bream (Sparus aurata L.).

Betancor MB, Sprague M, Montero D, Usher S, Sayanova O, Campbell PJ, Napier JA, Caballero MJ, Izquierdo M, Tocher DR.

Lipids. 2016 Oct;51(10):1171-1191. doi: 10.1007/s11745-016-4191-4. Epub 2016 Sep 2. Erratum in: Lipids. 2017 May;52(5):463.

17.

Dual Fatty Acid Elongase Complex Interactions in Arabidopsis.

Morineau C, Gissot L, Bellec Y, Hematy K, Tellier F, Renne C, Haslam R, Beaudoin F, Napier J, Faure JD.

PLoS One. 2016 Sep 1;11(9):e0160631. doi: 10.1371/journal.pone.0160631. eCollection 2016.

18.

Towards the development of a sustainable soya bean-based feedstock for aquaculture.

Park H, Weier S, Razvi F, Peña PA, Sims NA, Lowell J, Hungate C, Kissinger K, Key G, Fraser P, Napier JA, Cahoon EB, Clemente TE.

Plant Biotechnol J. 2017 Feb;15(2):227-236. doi: 10.1111/pbi.12608. Epub 2016 Sep 13.

19.

Synthetic redesign of plant lipid metabolism.

Haslam RP, Sayanova O, Kim HJ, Cahoon EB, Napier JA.

Plant J. 2016 Jul;87(1):76-86. doi: 10.1111/tpj.13172. Epub 2016 Jun 20. Review.

20.

Nutritional Evaluation of an EPA-DHA Oil from Transgenic Camelina sativa in Feeds for Post-Smolt Atlantic Salmon (Salmo salar L.).

Betancor MB, Sprague M, Sayanova O, Usher S, Metochis C, Campbell PJ, Napier JA, Tocher DR.

PLoS One. 2016 Jul 25;11(7):e0159934. doi: 10.1371/journal.pone.0159934. eCollection 2016.

21.

Plant sphingolipids: Their importance in cellular organization and adaption.

Michaelson LV, Napier JA, Molino D, Faure JD.

Biochim Biophys Acta. 2016 Sep;1861(9 Pt B):1329-1335. doi: 10.1016/j.bbalip.2016.04.003. Epub 2016 Apr 13. Review.

22.

Field trial evaluation of the accumulation of omega-3 long chain polyunsaturated fatty acids in transgenic Camelina sativa: Making fish oil substitutes in plants.

Usher S, Haslam RP, Ruiz-Lopez N, Sayanova O, Napier JA.

Metab Eng Commun. 2015 Jul 9;2:93-98. eCollection 2015 Dec.

23.

Correction: The Zinc-Finger Protein SOP1 Is Required for a Subset of the Nuclear Exosome Functions in Arabidopsis.

Hématy K, Bellec Y, Podicheti R, Bouteiller N, Anne P, Morineau C, Haslam RP, Beaudoin F, Napier JA, Mockaitis K, Gagliardi D, Vaucheret H, Lange H, Faure JD.

PLoS Genet. 2016 Mar 23;12(3):e1005958. doi: 10.1371/journal.pgen.1005958. eCollection 2016 Mar. No abstract available.

24.

Heterotrophic Production of Omega-3 Long-Chain Polyunsaturated Fatty Acids by Trophically Converted Marine Diatom Phaeodactylum tricornutum.

Hamilton ML, Powers S, Napier JA, Sayanova O.

Mar Drugs. 2016 Mar 9;14(3). pii: E53. doi: 10.3390/md14030053.

25.

Transgenic plants as a sustainable, terrestrial source of fish oils.

Napier JA, Usher S, Haslam RP, Ruiz-Lopez N, Sayanova O.

Eur J Lipid Sci Technol. 2015 Sep;117(9):1317-1324. Epub 2015 Jun 23.

26.

The role of drought- and disturbance-mediated competition in shaping community responses to varied environments.

Napier JD, Mordecai EA, Heckman RW.

Oecologia. 2016 Jun;181(2):621-32. doi: 10.1007/s00442-016-3582-9. Epub 2016 Feb 18.

PMID:
26893230
27.

A retrospective study of the real-life utilization and effectiveness of ranibizumab therapy for neovascular age-related macular degeneration in the UK.

Hykin P, Chakravarthy U, Lotery A, McKibbin M, Napier J, Sivaprasad S.

Clin Ophthalmol. 2016 Jan 13;10:87-96. doi: 10.2147/OPTH.S92627. eCollection 2016.

28.

The Zinc-Finger Protein SOP1 Is Required for a Subset of the Nuclear Exosome Functions in Arabidopsis.

Hématy K, Bellec Y, Podicheti R, Bouteiller N, Anne P, Morineau C, Haslam RP, Beaudoin F, Napier JA, Mockaitis K, Gagliardi D, Vaucheret H, Lange H, Faure JD.

PLoS Genet. 2016 Feb 1;12(2):e1005817. doi: 10.1371/journal.pgen.1005817. eCollection 2016 Feb. Erratum in: PLoS Genet. 2016 Mar;12(3):e1005958.

29.

A Transgenic Camelina sativa Seed Oil Effectively Replaces Fish Oil as a Dietary Source of Eicosapentaenoic Acid in Mice.

Tejera N, Vauzour D, Betancor MB, Sayanova O, Usher S, Cochard M, Rigby N, Ruiz-Lopez N, Menoyo D, Tocher DR, Napier JA, Minihane AM.

J Nutr. 2016 Feb;146(2):227-35. doi: 10.3945/jn.115.223941. Epub 2016 Jan 20.

30.

Towards the Industrial Production of Omega-3 Long Chain Polyunsaturated Fatty Acids from a Genetically Modified Diatom Phaeodactylum tricornutum.

Hamilton ML, Warwick J, Terry A, Allen MJ, Napier JA, Sayanova O.

PLoS One. 2015 Dec 14;10(12):e0144054. doi: 10.1371/journal.pone.0144054. eCollection 2015.

31.

Evaluation of a high-EPA oil from transgenic Camelina sativa in feeds for Atlantic salmon (Salmo salar L.): Effects on tissue fatty acid composition, histology and gene expression.

Betancor MB, Sprague M, Sayanova O, Usher S, Campbell PJ, Napier JA, Caballero MJ, Tocher DR.

Aquaculture. 2015 Jul 1;444:1-12.

32.

The first crop plant genetically engineered to release an insect pheromone for defence.

Bruce TJ, Aradottir GI, Smart LE, Martin JL, Caulfield JC, Doherty A, Sparks CA, Woodcock CM, Birkett MA, Napier JA, Jones HD, Pickett JA.

Sci Rep. 2015 Jun 25;5:11183. doi: 10.1038/srep11183.

33.

Intragenus competition between coccolithoviruses: an insight on how a select few can come to dominate many.

Nissimov JI, Napier JA, Allen MJ, Kimmance SA.

Environ Microbiol. 2016 Jan;18(1):133-45. doi: 10.1111/1462-2920.12902. Epub 2015 Jun 25.

PMID:
25970076
34.

Sphingolipid metabolism is strikingly different between pollen and leaf in Arabidopsis as revealed by compositional and gene expression profiling.

Luttgeharm KD, Kimberlin AN, Cahoon RE, Cerny RL, Napier JA, Markham JE, Cahoon EB.

Phytochemistry. 2015 Jul;115:121-9. doi: 10.1016/j.phytochem.2015.02.019. Epub 2015 Mar 17.

PMID:
25794895
35.

Arabidopsis cytosolic acyl-CoA-binding proteins ACBP4, ACBP5 and ACBP6 have overlapping but distinct roles in seed development.

Hsiao AS, Haslam RP, Michaelson LV, Liao P, Chen QF, Sooriyaarachchi S, Mowbray SL, Napier JA, Tanner JA, Chye ML.

Biosci Rep. 2015 Feb 25;35(1). pii: e00176. No abstract available.

PMID:
25779482
36.

Molecular characterization of two isoforms of a farnesyl pyrophosphate synthase gene in wheat and their roles in sesquiterpene synthesis and inducible defence against aphid infestation.

Zhang Y, Li ZX, Yu XD, Fan J, Pickett JA, Jones HD, Zhou JJ, Birkett MA, Caulfield J, Napier JA, Zhao GY, Cheng XG, Shi Y, Bruce TJ, Xia LQ.

New Phytol. 2015 May;206(3):1101-15. doi: 10.1111/nph.13302. Epub 2015 Jan 30.

37.

An alternative pathway for the effective production of the omega-3 long-chain polyunsaturates EPA and ETA in transgenic oilseeds.

Ruiz-Lopez N, Haslam RP, Usher S, Napier JA, Sayanova O.

Plant Biotechnol J. 2015 Dec;13(9):1264-75. doi: 10.1111/pbi.12328. Epub 2015 Jan 30.

38.

A nutritionally-enhanced oil from transgenic Camelina sativa effectively replaces fish oil as a source of eicosapentaenoic acid for fish.

Betancor MB, Sprague M, Usher S, Sayanova O, Campbell PJ, Napier JA, Tocher DR.

Sci Rep. 2015 Jan 29;5:8104. doi: 10.1038/srep08104.

39.

ECERIFERUM2-LIKE proteins have unique biochemical and physiological functions in very-long-chain fatty acid elongation.

Haslam TM, Haslam R, Thoraval D, Pascal S, Delude C, Domergue F, Fernández AM, Beaudoin F, Napier JA, Kunst L, Joubès J.

Plant Physiol. 2015 Mar;167(3):682-92. doi: 10.1104/pp.114.253195. Epub 2015 Jan 16.

40.

Arabidopsis cytosolic acyl-CoA-binding proteins ACBP4, ACBP5 and ACBP6 have overlapping but distinct roles in seed development.

Hsiao AS, Haslam RP, Michaelson LV, Liao P, Chen QF, Sooriyaarachchi S, Mowbray SL, Napier JA, Tanner JA, Chye ML.

Biosci Rep. 2014 Dec 23;34(6):e00165. doi: 10.1042/BSR20140139. Erratum in: Biosci Rep. 2015;35(1). pii: e00176.

41.

Modifying the lipid content and composition of plant seeds: engineering the production of LC-PUFA.

Ruiz-Lopez N, Usher S, Sayanova OV, Napier JA, Haslam RP.

Appl Microbiol Biotechnol. 2015 Jan;99(1):143-54. doi: 10.1007/s00253-014-6217-2. Epub 2014 Nov 25. Review.

42.

Modifying fatty acid profiles through a new cytokinin-based plastid transformation system.

Dunne A, Maple-Grødem J, Gargano D, Haslam RP, Napier JA, Chua NH, Russell R, Møller SG.

Plant J. 2014 Dec;80(6):1131-8. doi: 10.1111/tpj.12684. Epub 2014 Nov 13.

43.

Gene expression in plant lipid metabolism in Arabidopsis seedlings.

Hsiao AS, Haslam RP, Michaelson LV, Liao P, Napier JA, Chye ML.

PLoS One. 2014 Sep 29;9(9):e107372. doi: 10.1371/journal.pone.0107372. eCollection 2014.

44.

Rice ORMDL controls sphingolipid homeostasis affecting fertility resulting from abnormal pollen development.

Chueasiri C, Chunthong K, Pitnjam K, Chakhonkaen S, Sangarwut N, Sangsawang K, Suksangpanomrung M, Michaelson LV, Napier JA, Muangprom A.

PLoS One. 2014 Sep 5;9(9):e106386. doi: 10.1371/journal.pone.0106386. eCollection 2014.

45.

Gluten quality of bread wheat is associated with activity of RabD GTPases.

Tyler AM, Bhandari DG, Poole M, Napier JA, Jones HD, Lu C, Lycett GW.

Plant Biotechnol J. 2015 Feb;13(2):163-76. doi: 10.1111/pbi.12231. Epub 2014 Jul 22.

46.

Understanding and manipulating plant lipid composition: Metabolic engineering leads the way.

Napier JA, Haslam RP, Beaudoin F, Cahoon EB.

Curr Opin Plant Biol. 2014 Jun;19:68-75. doi: 10.1016/j.pbi.2014.04.001. Epub 2014 May 6.

47.

Permanent draft genomes of four new coccolithoviruses: EhV-18, EhV-145, EhV-156 and EhV-164.

Nissimov JI, Napier JA, Kimmance SA, Allen MJ.

Mar Genomics. 2014 Jun;15:7-8. doi: 10.1016/j.margen.2014.02.004. Epub 2014 Mar 13.

PMID:
24631268
48.

The utilization of the acyl-CoA and the involvement PDAT and DGAT in the biosynthesis of erucic acid-rich triacylglycerols in Crambe seed oil.

Furmanek T, Demski K, Banaś W, Haslam R, Napier J, Stymne S, Banaś A.

Lipids. 2014 Apr;49(4):327-33. doi: 10.1007/s11745-014-3886-7. Epub 2014 Feb 28.

49.

Delivering sustainable crop protection systems via the seed: exploiting natural constitutive and inducible defence pathways.

Pickett JA, Aradottír GI, Birkett MA, Bruce TJ, Hooper AM, Midega CA, Jones HD, Matthes MC, Napier JA, Pittchar JO, Smart LE, Woodcock CM, Khan ZR.

Philos Trans R Soc Lond B Biol Sci. 2014 Feb 17;369(1639):20120281. doi: 10.1098/rstb.2012.0281. Print 2014 Apr 5. Review. Erratum in: Philos Trans R Soc Lond B Biol Sci. 2014 May 19;369(1642):20140053.

50.

Evaluating echocardiogram and indirect blood pressure results in male western lowland gorillas (Gorilla gorilla gorilla) during three phases of an anesthetic protocol.

Napier JE, Kutinsky IB, Armstrong DL, Orton D, Hicks CL, Waldoch J, Devlin WH.

J Zoo Wildl Med. 2013 Dec;44(4):875-81.

PMID:
24450045

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