Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 46

1.

Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability.

Iwai K, Yaguchi M, Nishimura K, Yamamoto Y, Tamura T, Nakata D, Dairiki R, Kawakita Y, Mizojiri R, Ito Y, Asano M, Maezaki H, Nakayama Y, Kaishima M, Hayashi K, Teratani M, Miyakawa S, Iwatani M, Miyamoto M, Klein MG, Lane W, Snell G, Tjhen R, He X, Pulukuri S, Nomura T.

EMBO Mol Med. 2018 May 16. pii: e8289. doi: 10.15252/emmm.201708289. [Epub ahead of print]

2.

CDK8/19 inhibition induces premature G1/S transition and ATR-dependent cell death in prostate cancer cells.

Nakamura A, Nakata D, Kakoi Y, Kunitomo M, Murai S, Ebara S, Hata A, Hara T.

Oncotarget. 2018 Feb 6;9(17):13474-13487. doi: 10.18632/oncotarget.24414. eCollection 2018 Mar 2.

3.

Studying anti-oxidative properties of inclusion complexes of α-lipoic acid with γ-cyclodextrin in single living fission yeast by confocal Raman microspectroscopy.

Noothalapati H, Ikarashi R, Iwasaki K, Nishida T, Kaino T, Yoshikiyo K, Terao K, Nakata D, Ikuta N, Ando M, Hamaguchi HO, Kawamukai M, Yamamoto T.

Spectrochim Acta A Mol Biomol Spectrosc. 2018 May 15;197:237-243. doi: 10.1016/j.saa.2018.02.011. Epub 2018 Feb 6.

PMID:
29433856
4.

Evaluation of pharmacokinetics/pharmacodynamics and efficacy of one-month depots of TAK-448 and TAK-683, investigational kisspeptin analogs, in male rats and an androgen-dependent prostate cancer model.

Tanaka A, Nakata D, Masaki T, Kusaka M, Watanabe T, Matsui H.

Eur J Pharmacol. 2018 Mar 5;822:138-146. doi: 10.1016/j.ejphar.2018.01.012.

PMID:
29355559
5.

Discovery of Novel 5-(Piperazine-1-carbonyl)pyridin-2(1H)-one Derivatives as Orally eIF4A3-Selective Inhibitors.

Mizojiri R, Nakata D, Satoh Y, Morishita D, Shibata S, Iwatani-Yoshihara M, Kosugi Y, Kosaka M, Takeda J, Sasaki S, Takami K, Fukuda K, Kamaura M, Sasaki S, Arai R, Cary DR, Imaeda Y.

ACS Med Chem Lett. 2017 Sep 8;8(10):1077-1082. doi: 10.1021/acsmedchemlett.7b00283. eCollection 2017 Oct 12.

PMID:
29057054
6.

Glycogen synthase kinase-3 inhibitors suppress the AR-V7-mediated transcription and selectively inhibit cell growth in AR-V7-positive prostate cancer cells.

Nakata D, Koyama R, Nakayama K, Kitazawa S, Watanabe T, Hara T.

Prostate. 2017 Jun;77(9):955-961. doi: 10.1002/pros.23351. Epub 2017 Apr 10.

PMID:
28397338
7.

The RNA helicase DDX39B and its paralog DDX39A regulate androgen receptor splice variant AR-V7 generation.

Nakata D, Nakao S, Nakayama K, Araki S, Nakayama Y, Aparicio S, Hara T, Nakanishi A.

Biochem Biophys Res Commun. 2017 Jan 29;483(1):271-276. doi: 10.1016/j.bbrc.2016.12.153. Epub 2016 Dec 23.

PMID:
28025139
8.

Growth Inhibition by Testosterone in an Androgen Receptor Splice Variant-Driven Prostate Cancer Model.

Nakata D, Nakayama K, Masaki T, Tanaka A, Kusaka M, Watanabe T.

Prostate. 2016 Dec;76(16):1536-1545. doi: 10.1002/pros.23238. Epub 2016 Jul 30.

PMID:
27473672
9.

Isomeric effects of anti-diabetic α-lipoic acid with γ-cyclodextrin.

Naito Y, Ikuta N, Okano A, Okamoto H, Nakata D, Terao K, Matsumoto K, Kajiwara N, Yasui H, Yoshikawa Y.

Life Sci. 2015 Sep 1;136:73-8. doi: 10.1016/j.lfs.2015.06.016. Epub 2015 Jul 2.

PMID:
26141985
10.

A study on the inhibitory mechanism for cholesterol absorption by α-cyclodextrin administration.

Furune T, Ikuta N, Ishida Y, Okamoto H, Nakata D, Terao K, Sakamoto N.

Beilstein J Org Chem. 2014 Dec 2;10:2827-35. doi: 10.3762/bjoc.10.300. eCollection 2014.

12.

Antidiabetic effect of the α-lipoic acid γ-cyclodextrin complex.

Naito Y, Ikuta N, Nakata D, Terao K, Matsumoto K, Kajiwara N, Okano A, Yasui H, Yoshikawa Y.

J Clin Biochem Nutr. 2014 Sep;55(2):97-102. doi: 10.3164/jcbn.14-56. Epub 2014 Sep 1.

13.

Micelle formation of coenzyme Q10 with dipotassium glycyrrhizate using inclusion complex of coenzyme Q10 with γ-cyclodextrin.

Uekaji Y, Onishi M, Nakata D, Terao K, Paananen A, Partanen R, Yoshii H.

J Phys Chem B. 2014 Oct 2;118(39):11480-6. doi: 10.1021/jp5065165. Epub 2014 Sep 18.

PMID:
25187379
14.

Pharmacologic profiles of investigational kisspeptin/metastin analogues, TAK-448 and TAK-683, in adult male rats in comparison to the GnRH analogue leuprolide.

Matsui H, Masaki T, Akinaga Y, Kiba A, Takatsu Y, Nakata D, Tanaka A, Ban J, Matsumoto S, Kumano S, Suzuki A, Ikeda Y, Yamaguchi M, Watanabe T, Ohtaki T, Kusaka M.

Eur J Pharmacol. 2014 Jul 15;735:77-85. doi: 10.1016/j.ejphar.2014.03.058. Epub 2014 Apr 18.

PMID:
24747751
15.

Suppression of the hypothalamic-pituitary-gonadal axis by TAK-385 (relugolix), a novel, investigational, orally active, small molecule gonadotropin-releasing hormone (GnRH) antagonist: studies in human GnRH receptor knock-in mice.

Nakata D, Masaki T, Tanaka A, Yoshimatsu M, Akinaga Y, Asada M, Sasada R, Takeyama M, Miwa K, Watanabe T, Kusaka M.

Eur J Pharmacol. 2014 Jan 15;723:167-74. doi: 10.1016/j.ejphar.2013.12.001. Epub 2013 Dec 11.

PMID:
24333551
16.

Analysis of the enhanced stability of r(+)-alpha lipoic Acid by the complex formation with cyclodextrins.

Ikuta N, Sugiyama H, Shimosegawa H, Nakane R, Ishida Y, Uekaji Y, Nakata D, Pallauf K, Rimbach G, Terao K, Matsugo S.

Int J Mol Sci. 2013 Feb 7;14(2):3639-55. doi: 10.3390/ijms14023639.

17.

Discovery of 1-{4-[1-(2,6-difluorobenzyl)-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl]phenyl}-3-methoxyurea (TAK-385) as a potent, orally active, non-peptide antagonist of the human gonadotropin-releasing hormone receptor.

Miwa K, Hitaka T, Imada T, Sasaki S, Yoshimatsu M, Kusaka M, Tanaka A, Nakata D, Furuya S, Endo S, Hamamura K, Kitazaki T.

J Med Chem. 2011 Jul 28;54(14):4998-5012. doi: 10.1021/jm200216q. Epub 2011 Jun 23.

PMID:
21657270
18.

Complexation of tocotrienol with gamma-cyclodextrin enhances intestinal absorption of tocotrienol in rats.

Ikeda S, Uchida T, Ichikawa T, Watanabe T, Uekaji Y, Nakata D, Terao K, Yano T.

Biosci Biotechnol Biochem. 2010;74(7):1452-7. Epub 2010 Jul 7.

19.

A novel androgen-dependent prostate cancer xenograft model derived from skin metastasis of a Japanese patient.

Kimura T, Kiyota H, Nakata D, Masaki T, Kusaka M, Egawa S.

Prostate. 2009 Nov 1;69(15):1660-7. doi: 10.1002/pros.21016.

PMID:
19644954
20.

Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses.

Drake PM, Nathan JK, Stock CM, Chang PV, Muench MO, Nakata D, Reader JR, Gip P, Golden KP, Weinhold B, Gerardy-Schahn R, Troy FA 2nd, Bertozzi CR.

J Immunol. 2008 Nov 15;181(10):6850-8.

23.

Neuronal nitric oxide synthase is crucial for ganglion cell death in rat retinal explant cultures.

Katsuki H, Yamamoto R, Nakata D, Kume T, Akaike A.

J Pharmacol Sci. 2004 Jan;94(1):77-80.

24.

Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.

Oshima K, Kakizawa S, Nishigawa H, Jung HY, Wei W, Suzuki S, Arashida R, Nakata D, Miyata S, Ugaki M, Namba S.

Nat Genet. 2004 Jan;36(1):27-9. Epub 2003 Dec 7.

PMID:
14661021
25.

Retinal neuronal death induced by intraocular administration of a nitric oxide donor and its rescue by neurotrophic factors in rats.

Takahata K, Katsuki H, Kume T, Nakata D, Ito K, Muraoka S, Yoneda F, Kashii S, Honda Y, Akaike A.

Invest Ophthalmol Vis Sci. 2003 Apr;44(4):1760-6.

PMID:
12657619
26.

Detection of TP53 mutation in ameloblastoma by the use of a yeast functional assay.

Shibata T, Nakata D, Chiba I, Yamashita T, Abiko Y, Tada M, Moriuchi T.

J Oral Pathol Med. 2002 Oct;31(9):534-8.

PMID:
12269992
27.

Enhancement of tumorigenic, metastatic and in vitro invasive capacity of rat mammary tumor cells by transforming growth factor-beta.

Nakata D, Hamada Ji, Ba Y, Matsushita K, Shibata T, Hosokawa M, Moriuchi T.

Cancer Lett. 2002 Jan 10;175(1):95-106.

PMID:
11734341
28.
29.

Molecular cloning of a unique CMP-sialic acid synthetase that effectively utilizes both deaminoneuraminic acid (KDN) and N-acetylneuraminic acid (Neu5Ac) as substrates.

Nakata D, Münster AK, Gerardy-Schahn R, Aoki N, Matsuda T, Kitajima K.

Glycobiology. 2001 Aug;11(8):685-92.

PMID:
11479279
30.

Reduction of acetals with samarium diiodide in acetonitrile in the presence of Lewis acids.

Kunishima M, Nakata D, Sakuma T, Kono K, Sato S, Tani S.

Chem Pharm Bull (Tokyo). 2001 Jan;49(1):97-100.

31.

Increased oxidative DNA damage in mammary tumor cells by continuous epidermal growth factor stimulation.

Hamada J, Nakata D, Nakae D, Kobayashi Y, Akai H, Konishi Y, Okada F, Shibata T, Hosokawa M, Moriuchi T.

J Natl Cancer Inst. 2001 Feb 7;93(3):214-9.

PMID:
11158190
32.

Transcriptional slippage of p53 gene enhanced by cellular damage in rat liver: monitoring the slippage by a yeast functional assay.

Ba Y, Tonoki H, Tada M, Nakata D, Hamada J, Moriuchi T.

Mutat Res. 2000 Feb 14;447(2):209-20.

PMID:
10751604
33.
34.

A functional and quantitative mutational analysis of p53 mutations in yeast indicates strand biases and different roles of mutations in DMBA- and BBN-induced tumors in rats

Yamamoto K, Nakata D, Tada M, Tonoki H, Nishida T, Hirai A, Ba Y, Aoyama T, Hamada J, Furuuchi K, Harada H, Hirai K, Shibahara N, Katsuoka Y, Moriuchi T.

Int J Cancer. 2000 Mar 15;85(6):898. No abstract available.

35.

Adenovirus type 5 E1A immortalizes primary rat cells expressing wild-type p53.

Yamashita T, Tonoki H, Nakata D, Yamano S, Segawa K, Moriuchi T.

Microbiol Immunol. 1999;43(11):1037-44.

36.

A functional and quantitative mutational analysis of p53 mutations in yeast indicates strand biases and different roles of mutations in DMBA- and BBN-induced tumors in rats.

Yamamoto K, Nakata D, Tada M, Tonoki H, Nishida T, Hirai A, Ba Y, Aoyama T, Hamada J, Furuuchi K, Harada H, Hirai K, Shibahara N, Katsuoka Y, Moriuchi T.

Int J Cancer. 1999 Nov 26;83(5):700-5. Erratum in: Int J Cancer 2000 Mar 15;85(6):898.

37.
38.

Elevated expression of free deaminoneuraminic acid in mammalian cells cultured in mannose-rich media.

Angata T, Nakata D, Matsuda T, Kitajima K.

Biochem Biophys Res Commun. 1999 Aug 2;261(2):326-31.

PMID:
10425185
39.

Inhibitory effects of malotilate on invasion and metastasis of rat mammary carcinoma cells by modifying the functions of vascular endothelial cells.

Nagayasu H, Hamada J, Kawano T, Konaka S, Nakata D, Shibata T, Arisue M, Hosokawa M, Takeichi N, Moriuchi T.

Br J Cancer. 1998 May;77(9):1371-7.

40.

Characterization of the progressive sublines derived from a weakly malignant cloned cell line, ER-1, co-inoculated subcutaneously with a foreign body.

Hamada J, Nagayasu H, Kawano T, Mizutani T, Nakata D, Hosokawa M, Takeichi N.

Clin Exp Metastasis. 1998 Apr;16(3):291-8.

PMID:
9568647
41.

Reversible and irreversible tumor progression of a weakly malignant rat mammary carcinoma cell line by in vitro exposure to epidermal growth factor.

Nagayasu H, Hamada J, Nakata D, Shibata T, Kobayashi M, Hosokawa M, Takeichi N.

Int J Oncol. 1998 Jan;12(1):197-202.

PMID:
9454905
42.

Characterization and Solubilization of Kaurenoic Acid Hydroxylase from Gibberella fujikuroi.

Jennings JC, Coolbaugh RC, Nakata DA, West CA.

Plant Physiol. 1993 Mar;101(3):925-930.

43.

[Preoperative and intraoperative bone measurement for ceramic implants. 2. Intraoperative bone measurement].

Nakata D.

Shikai Tenbo. 1978;51(3):583-7. Japanese. No abstract available.

PMID:
295000
44.

[Preoperative and intraoperative bone measurement for ceramic implants. 1. Preoperative bone measurement].

Nakata D.

Shikai Tenbo. 1978;51(2):377-83. Japanese. No abstract available.

PMID:
294985
45.

Defective function of a microsomal UDP-glucuronyltransferase in Gunn rats.

Nakata D, Zakim D, Vessey DA.

Proc Natl Acad Sci U S A. 1976 Feb;73(2):289-92.

46.

Modification of protein-lipid interactions in the Gunn rat by treatment of microsomal UDP-glucuronyltransferase with diethylnitrosamine.

Nakata D, Zakim D, Vessey DA.

Biochem Pharmacol. 1975 Oct 1;24(19):1823-5. No abstract available.

PMID:
823948

Supplemental Content

Loading ...
Support Center