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Items: 1 to 50 of 183

1.

Anaplastic lymphoma kinase mutation (ALK F1174C) in small cell carcinoma of the prostate and molecular response to alectinib.

Carneiro BA, Pamarthy S, Shah AN, Sagar V, Unno K, Han H, Yang XJ, Costa RB, Nagy RJ, Lanman RB, Kuzel TM, Ross JS, Gay L, Elvin JA, Ali SM, Cristofanilli M, Chae YK, Giles FJ, Abdulkadir SA.

Clin Cancer Res. 2018 Mar 20. pii: clincanres.0332.2018. doi: 10.1158/1078-0432.CCR-18-0332. [Epub ahead of print]

PMID:
29559559
2.

Characterization of metastatic urothelial carcinoma via comprehensive genomic profiling of circulating tumor DNA.

Agarwal N, Pal SK, Hahn AW, Nussenzveig RH, Pond GR, Gupta SV, Wang J, Bilen MA, Naik G, Ghatalia P, Hoimes CJ, Gopalakrishnan D, Barata PC, Drakaki A, Faltas BM, Kiedrowski LA, Lanman RB, Nagy RJ, Vogelzang NJ, Boucher KM, Vaishampayan UN, Sonpavde G, Grivas P.

Cancer. 2018 Mar 8. doi: 10.1002/cncr.31314. [Epub ahead of print]

PMID:
29517810
3.

Targeted therapies for targeted populations: Anti-EGFR treatment for EGFR amplified gastroesophageal adenocarcinoma.

Maron SB, Alpert L, Kwak HA, Lomnicki S, Chase L, Xu D, O'Day E, Nagy RJ, Lanman RB, Cecchi F, Hembrough T, Schrock A, Hart J, Xiao SY, Setia N, Catenacci DVT.

Cancer Discov. 2018 Feb 15. pii: CD-17-1260. doi: 10.1158/2159-8290.CD-17-1260. [Epub ahead of print]

PMID:
29449271
4.

Genomic analysis of family data reveals additional genetic effects on intelligence and personality.

Hill WD, Arslan RC, Xia C, Luciano M, Amador C, Navarro P, Hayward C, Nagy R, Porteous DJ, McIntosh AM, Deary IJ, Haley CS, Penke L.

Mol Psychiatry. 2018 Jan 10. doi: 10.1038/s41380-017-0005-1. [Epub ahead of print]

PMID:
29321673
5.

PIK3CA C2 Domain Deletions Hyperactivate Phosphoinositide 3-kinase (PI3K), Generate Oncogene Dependence, and Are Exquisitely Sensitive to PI3Kα Inhibitors.

Croessmann S, Sheehan JH, Lee KM, Sliwoski G, He J, Nagy R, Riddle D, Mayer IA, Balko JM, Lanman R, Miller VA, Cantley LC, Meiler J, Arteaga CL.

Clin Cancer Res. 2018 Mar 15;24(6):1426-1435. doi: 10.1158/1078-0432.CCR-17-2141. Epub 2017 Dec 28.

PMID:
29284706
6.

Polyclonal RB1 mutations and acquired resistance to CDK 4/6 inhibitors in patients with metastatic breast cancer.

Condorelli R, Spring L, O'Shaughnessy J, Lacroix L, Bailleux C, Scott V, Dubois J, Nagy RJ, Lanman RB, Iafrate AJ, Andre F, Bardia A.

Ann Oncol. 2018 Mar 1;29(3):640-645. doi: 10.1093/annonc/mdx784.

PMID:
29236940
7.

Genomic Landscape of Cell-Free DNA in Patients with Colorectal Cancer.

Strickler JH, Loree JM, Ahronian LG, Parikh AR, Niedzwiecki D, Pereira AAL, McKinney M, Korn WM, Atreya CE, Banks KC, Nagy RJ, Meric-Bernstam F, Lanman RB, Talasaz A, Tsigelny IF, Corcoran RB, Kopetz S.

Cancer Discov. 2018 Feb;8(2):164-173. doi: 10.1158/2159-8290.CD-17-1009. Epub 2017 Dec 1.

PMID:
29196463
8.

Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank.

Howard DM, Hall LS, Hafferty JD, Zeng Y, Adams MJ, Clarke TK, Porteous DJ, Nagy R, Hayward C, Smith BH, Murray AD, Ryan NM, Evans KL, Haley CS, Deary IJ, Thomson PA, McIntosh AM.

Transl Psychiatry. 2017 Nov 30;7(11):1263. doi: 10.1038/s41398-017-0010-9.

9.

Cell-Free DNA and Circulating Tumor Cells: Comprehensive Liquid Biopsy Analysis in Advanced Breast Cancer.

Rossi G, Mu Z, Rademaker AW, Austin LK, Strickland KS, Costa RLB, Nagy RJ, Zagonel V, Taxter TJ, Behdad A, Wehbe FH, Platanias LC, Gradishar WJ, Cristofanilli M.

Clin Cancer Res. 2018 Feb 1;24(3):560-568. doi: 10.1158/1078-0432.CCR-17-2092. Epub 2017 Nov 27.

PMID:
29180605
10.

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity.

Joshi PK, Pirastu N, Kentistou KA, Fischer K, Hofer E, Schraut KE, Clark DW, Nutile T, Barnes CLK, Timmers PRHJ, Shen X, Gandin I, McDaid AF, Hansen TF, Gordon SD, Giulianini F, Boutin TS, Abdellaoui A, Zhao W, Medina-Gomez C, Bartz TM, Trompet S, Lange LA, Raffield L, van der Spek A, Galesloot TE, Proitsi P, Yanek LR, Bielak LF, Payton A, Murgia F, Concas MP, Biino G, Tajuddin SM, Seppälä I, Amin N, Boerwinkle E, Børglum AD, Campbell A, Demerath EW, Demuth I, Faul JD, Ford I, Gialluisi A, Gögele M, Graff M, Hingorani A, Hottenga JJ, Hougaard DM, Hurme MA, Ikram MA, Jylhä M, Kuh D, Ligthart L, Lill CM, Lindenberger U, Lumley T, Mägi R, Marques-Vidal P, Medland SE, Milani L, Nagy R, Ollier WER, Peyser PA, Pramstaller PP, Ridker PM, Rivadeneira F, Ruggiero D, Saba Y, Schmidt R, Schmidt H, Slagboom PE, Smith BH, Smith JA, Sotoodehnia N, Steinhagen-Thiessen E, van Rooij FJA, Verbeek AL, Vermeulen SH, Vollenweider P, Wang Y, Werge T, Whitfield JB, Zonderman AB, Lehtimäki T, Evans MK, Pirastu M, Fuchsberger C, Bertram L, Pendleton N, Kardia SLR, Ciullo M, Becker DM, Wong A, Psaty BM, van Duijn CM, Wilson JG, Jukema JW, Kiemeney L, Uitterlinden AG, Franceschini N, North KE, Weir DR, Metspalu A, Boomsma DI, Hayward C, Chasman D, Martin NG, Sattar N, Campbell H, Esko T, Kutalik Z, Wilson JF.

Nat Commun. 2017 Oct 13;8(1):910. doi: 10.1038/s41467-017-00934-5.

11.

Penetrance of a rare familial mutation predisposing to papillary thyroid cancer.

Saporito D, Brock P, Hampel H, Sipos J, Fernandez S, Liyanarachchi S, de la Chapelle A, Nagy R.

Fam Cancer. 2017 Oct 12. doi: 10.1007/s10689-017-0048-0. [Epub ahead of print]

PMID:
29027612
12.

Haplotype-based association analysis of general cognitive ability in Generation Scotland, the English Longitudinal Study of Ageing, and UK Biobank.

Howard DM, Adams MJ, Clarke TK, Wigmore EM, Zeng Y, Hagenaars SP, Lyall DM, Thomson PA, Evans KL, Porteous DJ, Nagy R, Hayward C, Haley CS, Smith BH, Murray AD, Batty GD, Deary IJ, McIntosh AM.

Wellcome Open Res. 2017 Aug 10;2:61. doi: 10.12688/wellcomeopenres.12171.1. eCollection 2017.

13.

Regional variation in health is predominantly driven by lifestyle rather than genetics.

Amador C, Xia C, Nagy R, Campbell A, Porteous D, Smith BH, Hastie N, Vitart V, Hayward C, Navarro P, Haley CS.

Nat Commun. 2017 Oct 6;8(1):801. doi: 10.1038/s41467-017-00497-5.

14.

Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma.

Pectasides E, Stachler MD, Derks S, Liu Y, Maron S, Islam M, Alpert L, Kwak H, Kindler H, Polite B, Sharma MR, Allen K, O'Day E, Lomnicki S, Maranto M, Kanteti R, Fitzpatrick C, Weber C, Setia N, Xiao SY, Hart J, Nagy RJ, Kim KM, Choi MG, Min BH, Nason KS, O'Keefe L, Watanabe M, Baba H, Lanman R, Agoston AT, Oh DJ, Dunford A, Thorner AR, Ducar MD, Wollison BM, Coleman HA, Ji Y, Posner MC, Roggin K, Turaga K, Chang P, Hogarth K, Siddiqui U, Gelrud A, Ha G, Freeman SS, Rhoades J, Reed S, Gydush G, Rotem D, Davison J, Imamura Y, Adalsteinsson V, Lee J, Bass AJ, Catenacci DV.

Cancer Discov. 2018 Jan;8(1):37-48. doi: 10.1158/2159-8290.CD-17-0395. Epub 2017 Oct 4.

PMID:
28978556
15.

Discrimination of Germline EGFR T790M Mutations in Plasma Cell-Free DNA Allows Study of Prevalence Across 31,414 Cancer Patients.

Hu Y, Alden RS, Odegaard JI, Fairclough SR, Chen R, Heng J, Feeney N, Nagy RJ, Shah J, Ulrich B, Gutierrez M, Lanman RB, Garber JE, Paweletz CP, Oxnard GR.

Clin Cancer Res. 2017 Dec 1;23(23):7351-7359. doi: 10.1158/1078-0432.CCR-17-1745. Epub 2017 Sep 25.

PMID:
28947568
16.

Epicuticular chemistry reinforces the new taxonomic classification of the Bactrocera dorsalis species complex (Diptera: Tephritidae, Dacinae).

Vaníčková L, Nagy R, Pompeiano A, Kalinová B.

PLoS One. 2017 Sep 5;12(9):e0184102. doi: 10.1371/journal.pone.0184102. eCollection 2017.

17.

The association of lifetime physical inactivity with head and neck cancer: a hospital-based case-control analysis.

Platek AJ, Cannioto RA, Etter JL, Kim J, Joseph JM, Gulati NR, Schmitt KL, Callahan E, Khachatryan E, Nagy R, Minlikeeva A, Brian Szender J, Singh AK, Danziger I, Moysich KB.

Eur Arch Otorhinolaryngol. 2017 Oct;274(10):3773-3780. doi: 10.1007/s00405-017-4688-3. Epub 2017 Aug 5.

PMID:
28780667
18.

The association of lifetime physical inactivity with bladder and renal cancer risk: A hospital-based case-control analysis.

Cannioto R, Etter JL, Guterman LB, Joseph JM, Gulati NR, Schmitt KL, LaMonte MJ, Nagy R, Minlikeeva A, Szender JB, Moysich KB.

Cancer Epidemiol. 2017 Aug;49:24-29. doi: 10.1016/j.canep.2017.04.017. Epub 2017 May 18.

PMID:
28528291
19.

Determinants of retinal microvascular features and their relationships in two European populations.

Kirin M, Nagy R, MacGillivray TJ, Polašek O, Hayward C, Rudan I, Campbell H, Wild S, Wright AF, Wilson JF, Vitart V.

J Hypertens. 2017 Aug;35(8):1646-1659. doi: 10.1097/HJH.0000000000001408.

20.

[A rare cause of hyponatraemia: McKittrick-Wheelock syndrome. Case report].

Nagy R, Márkus C, Jáger L, Tóth C, Lőcsei Z.

Orv Hetil. 2017 May;158(18):711-714. doi: 10.1556/650.2017.30753. Hungarian.

PMID:
28468538
21.

Cancer Genetic Counseling and Testing in an Era of Rapid Change.

Hooker GW, Clemens KR, Quillin J, Vogel Postula KJ, Summerour P, Nagy R, Buchanan AH.

J Genet Couns. 2017 Dec;26(6):1244-1253. doi: 10.1007/s10897-017-0099-2. Epub 2017 Apr 22.

PMID:
28434142
22.

An Acquired HER2T798I Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant-Driven Breast Cancer.

Hanker AB, Brewer MR, Sheehan JH, Koch JP, Sliwoski GR, Nagy R, Lanman R, Berger MF, Hyman DM, Solit DB, He J, Miller V, Cutler RE Jr, Lalani AS, Cross D, Lovly CM, Meiler J, Arteaga CL.

Cancer Discov. 2017 Jun;7(6):575-585. doi: 10.1158/2159-8290.CD-16-1431. Epub 2017 Mar 8.

PMID:
28274957
23.

Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.

Nagy R, Boutin TS, Marten J, Huffman JE, Kerr SM, Campbell A, Evenden L, Gibson J, Amador C, Howard DM, Navarro P, Morris A, Deary IJ, Hocking LJ, Padmanabhan S, Smith BH, Joshi P, Wilson JF, Hastie ND, Wright AF, McIntosh AM, Porteous DJ, Haley CS, Vitart V, Hayward C.

Genome Med. 2017 Mar 7;9(1):23. doi: 10.1186/s13073-017-0414-4.

24.

Human-started wildfires expand the fire niche across the United States.

Balch JK, Bradley BA, Abatzoglou JT, Nagy RC, Fusco EJ, Mahood AL.

Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):2946-2951. doi: 10.1073/pnas.1617394114. Epub 2017 Feb 27.

25.

Genetic Stratification to Identify Risk Groups for Alzheimer's Disease.

Marioni RE, Campbell A, Hagenaars SP, Nagy R, Amador C, Hayward C, Porteous DJ, Visscher PM, Deary IJ.

J Alzheimers Dis. 2017;57(1):275-283. doi: 10.3233/JAD-161070.

26.

Nutrient limitation in tropical secondary forests following different management practices.

Nagy RC, Rastetter EB, Neill C, Porder S.

Ecol Appl. 2017 Apr;27(3):734-755. doi: 10.1002/eap.1478. Epub 2017 Mar 15.

PMID:
27930831
27.

Shared Genetics and Couple-Associated Environment Are Major Contributors to the Risk of Both Clinical and Self-Declared Depression.

Zeng Y, Navarro P, Xia C, Amador C, Fernandez-Pujals AM, Thomson PA, Campbell A, Nagy R, Clarke TK, Hafferty JD, Smith BH, Hocking LJ, Padmanabhan S, Hayward C, MacIntyre DJ, Porteous DJ, Haley CS, McIntosh AM.

EBioMedicine. 2016 Dec;14:161-167. doi: 10.1016/j.ebiom.2016.11.003. Epub 2016 Nov 4.

28.

Risk Factors of 131I-Induced Salivary Gland Damage in Thyroid Cancer Patients.

Hollingsworth B, Senter L, Zhang X, Brock GN, Jarjour W, Nagy R, Brock P, Coombes KR, Kloos RT, Ringel MD, Sipos J, Lattimer I, Carrau R, Jhiang SM.

J Clin Endocrinol Metab. 2016 Nov;101(11):4085-4093. Epub 2016 Aug 17.

29.

Genetic variants linked to education predict longevity.

Marioni RE, Ritchie SJ, Joshi PK, Hagenaars SP, Okbay A, Fischer K, Adams MJ, Hill WD, Davies G; Social Science Genetic Association Consortium, Nagy R, Amador C, Läll K, Metspalu A, Liewald DC, Campbell A, Wilson JF, Hayward C, Esko T, Porteous DJ, Gale CR, Deary IJ.

Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):13366-13371. Epub 2016 Oct 31.

30.

O.02: Plasma Next Generation Sequencing of Over 5,000 Advanced Non-Small Cell Lung Cancer Patients With Clinical Correlations.

Mack PC, Banks KC, Zill OA, Mortimer SA, Chudova DI, Odegaard J, Lee CE, Nagy RJ, Eltoukhy H, Talasaz A, Lanman R, Gandara DR.

J Thorac Oncol. 2016 Oct;11(10S):S168-S169. doi: 10.1016/j.jtho.2016.08.005. Epub 2016 Sep 22. No abstract available.

31.

Citrobacter freundii as a test platform for recombinant cellulose degradation systems.

Lakhundi SS, Duedu KO, Cain N, Nagy R, Krakowiak J, French CE.

Lett Appl Microbiol. 2017 Jan;64(1):35-42. doi: 10.1111/lam.12668. Epub 2016 Nov 21.

PMID:
27617802
32.

Biopsy-free circulating tumor DNA assay identifies actionable mutations in lung cancer.

Villaflor V, Won B, Nagy R, Banks K, Lanman RB, Talasaz A, Salgia R.

Oncotarget. 2016 Oct 11;7(41):66880-66891. doi: 10.18632/oncotarget.11801.

33.

Genetic variants in thyroid cancer distant metastases.

Justiniano SE, McElroy JP, Yu L, Yilmaz AS, Coombes KR, Senter L, Nagy R, Wakely P Jr, Volinia S, Vinco M, Giordano TJ, Croce CM, Saji M, Ringel MD.

Endocr Relat Cancer. 2016 Oct;23(10):L33-6. doi: 10.1530/ERC-16-0351. Epub 2016 Aug 19. No abstract available.

34.

Costs of Diagnostic Assessment for Lung Cancer: A Medicare Claims Analysis.

Lokhandwala T, Bittoni MA, Dann RA, D'Souza AO, Johnson M, Nagy RJ, Lanman RB, Merritt RE, Carbone DP.

Clin Lung Cancer. 2017 Jan;18(1):e27-e34. doi: 10.1016/j.cllc.2016.07.006. Epub 2016 Jul 21.

PMID:
27530054
35.

Hyperglycemia Induces Bioenergetic Changes in Adipose-Derived Stromal Cells While Their Pericytic Function Is Retained.

Hajmousa G, Elorza AA, Nies VJ, Jensen EL, Nagy RA, Harmsen MC.

Stem Cells Dev. 2016 Oct 1;25(19):1444-53. doi: 10.1089/scd.2016.0025. Epub 2016 Sep 1.

PMID:
27473785
36.

Papillary Thyroid Carcinoma: Association Between Germline DNA Variant Markers and Clinical Parameters.

Jendrzejewski J, Liyanarachchi S, Nagy R, Senter L, Wakely PE, Thomas A, Nabhan F, He H, Li W, Sworczak K, Ringel MD, Kirschner LS, de la Chapelle A.

Thyroid. 2016 Sep;26(9):1276-84. doi: 10.1089/thy.2015.0665. Epub 2016 Jul 22.

37.

Global combustion: the connection between fossil fuel and biomass burning emissions (1997-2010).

Balch JK, Nagy RC, Archibald S, Bowman DM, Moritz MA, Roos CI, Scott AC, Williamson GJ.

Philos Trans R Soc Lond B Biol Sci. 2016 Jun 5;371(1696). pii: 20150177. doi: 10.1098/rstb.2015.0177.

38.

Impact of Physical Inactivity on Risk of Developing Cancer of the Uterine Cervix: A Case-Control Study.

Szender JB, Cannioto R, Gulati NR, Schmitt KL, Friel G, Minlikeeva A, Platek A, Gower EH, Nagy R, Khachatryan E, Mayor PC, Kasza KA, Lele SB, Odunsi K, Moysich KB.

J Low Genit Tract Dis. 2016 Jul;20(3):230-3. doi: 10.1097/LGT.0000000000000210.

39.

Plasma T790M Result Alters Treatment Options in a Previously T790 Wild-Type EGFR-Mutant Lung Cancer.

Piotrowska Z, Drapkin B, Engelman JA, Nagy RJ, Lanman RB, Sequist LV.

J Thorac Oncol. 2016 Aug;11(8):e95-e97. doi: 10.1016/j.jtho.2016.03.020. Epub 2016 Apr 12. No abstract available.

40.

Rapid, Bioassay-Guided Process for the Detection and Identification of Antibacterial Neem Oil Compounds.

Krüzselyi D, Nagy R, Ott PG, Móricz ÁM.

J Chromatogr Sci. 2016 Aug;54(7):1084-9. doi: 10.1093/chromsci/bmw026. Epub 2016 Mar 6.

PMID:
26951543
41.

Structure and composition of altered riparian forests in an agricultural Amazonian landscape.

Nagy RC, Porder S, Neill C, Brando P, Quintino RM, do Nascimento SA.

Ecol Appl. 2015 Sep;25(6):1725-38.

PMID:
26552277
42.

PTCSC3 Is Involved in Papillary Thyroid Carcinoma Development by Modulating S100A4 Gene Expression.

Jendrzejewski J, Thomas A, Liyanarachchi S, Eiterman A, Tomsic J, He H, Radomska HS, Li W, Nagy R, Sworczak K, de la Chapelle A.

J Clin Endocrinol Metab. 2015 Oct;100(10):E1370-7. doi: 10.1210/jc.2015-2247. Epub 2015 Aug 14.

43.

The current state of cancer genetic counseling access and availability.

Knapke S, Haidle JL, Nagy R, Pirzadeh-Miller S.

Genet Med. 2016 Apr;18(4):410-2. doi: 10.1038/gim.2015.98. Epub 2015 Aug 6.

PMID:
26248009
44.

A germline mutation in SRRM2, a splicing factor gene, is implicated in papillary thyroid carcinoma predisposition.

Tomsic J, He H, Akagi K, Liyanarachchi S, Pan Q, Bertani B, Nagy R, Symer DE, Blencowe BJ, de la Chapelle A.

Sci Rep. 2015 Jul 2;5:10566. doi: 10.1038/srep10566.

45.

Non-invasive in vivo time-dependent strain measurement method in human abdominal aortic aneurysms: Towards a novel approach to rupture risk estimation.

Nagy R, Csobay-Novák C, Lovas A, Sótonyi P, Bojtár I.

J Biomech. 2015 Jul 16;48(10):1876-86. doi: 10.1016/j.jbiomech.2015.04.030. Epub 2015 Apr 28.

PMID:
25980555
46.

Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer.

He H, Li W, Liyanarachchi S, Srinivas M, Wang Y, Akagi K, Wang Y, Wu D, Wang Q, Jin V, Symer DE, Shen R, Phay J, Nagy R, de la Chapelle A.

Proc Natl Acad Sci U S A. 2015 May 12;112(19):6128-33. doi: 10.1073/pnas.1506255112. Epub 2015 Apr 27.

47.

Genomic prediction of complex human traits: relatedness, trait architecture and predictive meta-models.

Spiliopoulou A, Nagy R, Bermingham ML, Huffman JE, Hayward C, Vitart V, Rudan I, Campbell H, Wright AF, Wilson JF, Pong-Wong R, Agakov F, Navarro P, Haley CS.

Hum Mol Genet. 2015 Jul 15;24(14):4167-82. doi: 10.1093/hmg/ddv145. Epub 2015 Apr 26.

48.

Detection of sex chromosome aneuploidies using quantitative fluorescent PCR in the Hungarian population.

Nagy B, Nagy RG, Lazar L, Schonleber J, Papp C, Rigo J Jr.

Clin Chim Acta. 2015 May 20;445:2-6. doi: 10.1016/j.cca.2015.03.009. Epub 2015 Mar 16.

PMID:
25791892
49.

Presence of bile acids in human follicular fluid and their relation with embryo development in modified natural cycle IVF.

Nagy RA, van Montfoort AP, Dikkers A, van Echten-Arends J, Homminga I, Land JA, Hoek A, Tietge UJ.

Hum Reprod. 2015 May;30(5):1102-9. doi: 10.1093/humrep/dev034. Epub 2015 Mar 8.

PMID:
25753582
50.

Germline and somatic SDHx alterations in apparently sporadic differentiated thyroid cancer.

Ni Y, Seballos S, Ganapathi S, Gurin D, Fletcher B, Ngeow J, Nagy R, Kloos RT, Ringel MD, LaFramboise T, Eng C.

Endocr Relat Cancer. 2015 Apr;22(2):121-30. doi: 10.1530/ERC-14-0537.

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