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Items: 25

1.

Inhibin is a novel paracrine factor for tumor angiogenesis and metastasis.

Singh P, Jenkins LM, Horst B, Alers V, Pradhan S, Kaur P, Srivastava T, Hempel N, Győrffy B, Broude EV, Lee NY, Mythreye K.

Cancer Res. 2018 Mar 13. pii: canres.2316.2017. doi: 10.1158/0008-5472.CAN-17-2316. [Epub ahead of print]

PMID:
29535220
2.

Dually modified transmembrane proteoglycans in development and disease.

Jenkins LM, Horst B, Lancaster CL, Mythreye K.

Cytokine Growth Factor Rev. 2018 Feb;39:124-136. doi: 10.1016/j.cytogfr.2017.12.003. Epub 2017 Dec 22. Review.

PMID:
29291930
3.

Insights into the Dichotomous Regulation of SOD2 in Cancer.

Kim YS, Gupta Vallur P, Phaëton R, Mythreye K, Hempel N.

Antioxidants (Basel). 2017 Nov 3;6(4). pii: E86. doi: 10.3390/antiox6040086. Review.

4.

TGF-β triggers rapid fibrillogenesis via a novel TβRII-dependent fibronectin-trafficking mechanism.

Varadaraj A, Jenkins LM, Singh P, Chanda A, Snider J, Lee NY, Amsalem-Zafran AR, Ehrlich M, Henis YI, Mythreye K.

Mol Biol Cell. 2017 May 1;28(9):1195-1207. doi: 10.1091/mbc.E16-08-0601. Epub 2017 Mar 15.

5.

Altering the Proteoglycan State of Transforming Growth Factor β Type III Receptor (TβRIII)/Betaglycan Modulates Canonical Wnt/β-Catenin Signaling.

Jenkins LM, Singh P, Varadaraj A, Lee NY, Shah S, Flores HV, O'Connell K, Mythreye K.

J Biol Chem. 2016 Dec 2;291(49):25716-25728. Epub 2016 Oct 26.

6.

Activation of Mitofusin2 by Smad2-RIN1 Complex during Mitochondrial Fusion.

Kumar S, Pan CC, Shah N, Wheeler SE, Hoyt KR, Hempel N, Mythreye K, Lee NY.

Mol Cell. 2016 May 19;62(4):520-31. doi: 10.1016/j.molcel.2016.04.010. Epub 2016 May 12.

7.

Angiostatic actions of capsicodendrin through selective inhibition of VEGFR2-mediated AKT signaling and disregulated autophagy.

Pan CC, Shah N, Kumar S, Wheeler SE, Cinti J, Hoyt DG, Beattie CE, An M, Mythreye K, Rakotondraibe LH, Lee NY.

Oncotarget. 2017 Feb 21;8(8):12675-12685. doi: 10.18632/oncotarget.9307.

8.

Epigenetic Regulation of GDF2 Suppresses Anoikis in Ovarian and Breast Epithelia.

Varadaraj A, Patel P, Serrao A, Bandyopadhay T, Lee NY, Jazaeri AA, Huang Z, Murphy SK, Mythreye K.

Neoplasia. 2015 Nov;17(11):826-38. doi: 10.1016/j.neo.2015.11.003.

9.

Endoglin Regulation of Smad2 Function Mediates Beclin1 Expression and Endothelial Autophagy.

Pan CC, Kumar S, Shah N, Bloodworth JC, Hawinkels LJ, Mythreye K, Hoyt DG, Lee NY.

J Biol Chem. 2015 Jun 12;290(24):14884-92. doi: 10.1074/jbc.M114.630178. Epub 2015 Apr 30.

10.

TGF-β regulates LARG and GEF-H1 during EMT to affect stiffening response to force and cell invasion.

Osborne LD, Li GZ, How T, O'Brien ET, Blobe GC, Superfine R, Mythreye K.

Mol Biol Cell. 2014 Nov 5;25(22):3528-40. doi: 10.1091/mbc.E14-05-1015. Epub 2014 Aug 20.

11.

Src-mediated post-translational regulation of endoglin stability and function is critical for angiogenesis.

Pan CC, Kumar S, Shah N, Hoyt DG, Hawinkels LJ, Mythreye K, Lee NY.

J Biol Chem. 2014 Sep 12;289(37):25486-96. doi: 10.1074/jbc.M114.578609. Epub 2014 Jul 28.

12.

Type III TGF-β receptor promotes FGF2-mediated neuronal differentiation in neuroblastoma.

Knelson EH, Gaviglio AL, Tewari AK, Armstrong MB, Mythreye K, Blobe GC.

J Clin Invest. 2013 Nov;123(11):4786-98.

13.

The type III TGFβ receptor regulates filopodia formation via a Cdc42-mediated IRSp53-N-WASP interaction in epithelial cells.

Oh SY, Knelson EH, Blobe GC, Mythreye K.

Biochem J. 2013 Aug 15;454(1):79-89. doi: 10.1042/BJ20121701.

14.

Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells.

Tian H, Mythreye K, Golzio C, Katsanis N, Blobe GC.

EMBO J. 2012 Oct 3;31(19):3885-900. doi: 10.1038/emboj.2012.246. Epub 2012 Aug 31.

15.

Endoglin inhibits ERK-induced c-Myc and cyclin D1 expression to impede endothelial cell proliferation.

Pan CC, Bloodworth JC, Mythreye K, Lee NY.

Biochem Biophys Res Commun. 2012 Aug 3;424(3):620-3. doi: 10.1016/j.bbrc.2012.06.163. Epub 2012 Jul 10.

16.

TβRIII/β-arrestin2 regulates integrin α5β1 trafficking, function, and localization in epithelial cells.

Mythreye K, Knelson EH, Gatza CE, Gatza ML, Blobe GC.

Oncogene. 2013 Mar 14;32(11):1416-27. doi: 10.1038/onc.2012.157. Epub 2012 May 7.

17.

Mechanical stiffness grades metastatic potential in patient tumor cells and in cancer cell lines.

Swaminathan V, Mythreye K, O'Brien ET, Berchuck A, Blobe GC, Superfine R.

Cancer Res. 2011 Aug 1;71(15):5075-80. doi: 10.1158/0008-5472.CAN-11-0247. Epub 2011 Jun 3.

18.

The type III transforming growth factor-β receptor inhibits proliferation, migration, and adhesion in human myeloma cells.

Lambert KE, Huang H, Mythreye K, Blobe GC.

Mol Biol Cell. 2011 May;22(9):1463-72. doi: 10.1091/mbc.E10-11-0877. Epub 2011 Mar 16.

19.

The type III TGFbeta receptor regulates directional migration: new tricks for an old dog.

Mythreye K, Blobe GC.

Cell Cycle. 2009 Oct 1;8(19):3069-70. Epub 2009 Oct 8.

PMID:
19755845
20.

Proteoglycan signaling co-receptors: roles in cell adhesion, migration and invasion.

Mythreye K, Blobe GC.

Cell Signal. 2009 Nov;21(11):1548-58. doi: 10.1016/j.cellsig.2009.05.001. Epub 2009 May 8. Review.

21.

The type III TGF-beta receptor regulates epithelial and cancer cell migration through beta-arrestin2-mediated activation of Cdc42.

Mythreye K, Blobe GC.

Proc Natl Acad Sci U S A. 2009 May 19;106(20):8221-6. doi: 10.1073/pnas.0812879106. Epub 2009 May 1.

22.

ApoA-I induced CD31 in bone marrow-derived vascular progenitor cells increases adhesion: implications for vascular repair.

Mythreye K, Satterwhite LL, Davidson WS, Goldschmidt-Clermont PJ.

Biochim Biophys Acta. 2008 Nov-Dec;1781(11-12):703-9. doi: 10.1016/j.bbalip.2008.08.002. Epub 2008 Aug 16.

23.

The microtubule-based motor Kar3 and plus end-binding protein Bim1 provide structural support for the anaphase spindle.

Gardner MK, Haase J, Mythreye K, Molk JN, Anderson M, Joglekar AP, O'Toole ET, Winey M, Salmon ED, Odde DJ, Bloom K.

J Cell Biol. 2008 Jan 14;180(1):91-100. doi: 10.1083/jcb.200710164. Epub 2008 Jan 7.

24.

Reactive oxygen species in vascular endothelial cell motility. Roles of NAD(P)H oxidase and Rac1.

Moldovan L, Mythreye K, Goldschmidt-Clermont PJ, Satterwhite LL.

Cardiovasc Res. 2006 Jul 15;71(2):236-46. Epub 2006 May 9. Review.

PMID:
16782079

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