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Items: 7


The T-cell leukemia related rpl10-R98S mutant traps the 60S export adapter Nmd3 in the ribosomal P site in yeast.

Patchett S, Musalgaonkar S, Malyutin AG, Johnson AW.

PLoS Genet. 2017 Jul 17;13(7):e1006894. doi: 10.1371/journal.pgen.1006894. eCollection 2017 Jul.


Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis.

Malyutin AG, Musalgaonkar S, Patchett S, Frank J, Johnson AW.

EMBO J. 2017 Apr 3;36(7):854-868. doi: 10.15252/embj.201696012. Epub 2017 Feb 8.


Structural and Functional Characterization of Programmed Ribosomal Frameshift Signals in West Nile Virus Strains Reveals High Structural Plasticity Among cis-Acting RNA Elements.

Moomau C, Musalgaonkar S, Khan YA, Jones JE, Dinman JD.

J Biol Chem. 2016 Jul 22;291(30):15788-95. doi: 10.1074/jbc.M116.735613. Epub 2016 May 23.


Ribosomal protein uS19 mutants reveal its role in coordinating ribosome structure and function.

Bowen AM, Musalgaonkar S, Moomau CA, Gulay SP, Mirvis M, Dinman JD.

Translation (Austin). 2015 Nov 18;3(2):e1117703. doi: 10.1080/21690731.2015.1117703. eCollection 2015 Jul-Dec.


Ribosomes in the balance: structural equilibrium ensures translational fidelity and proper gene expression.

Musalgaonkar S, Moomau CA, Dinman JD.

Nucleic Acids Res. 2014 Dec 1;42(21):13384-92. doi: 10.1093/nar/gku1020. Epub 2014 Nov 11.


Ribosomal frameshifting in the CCR5 mRNA is regulated by miRNAs and the NMD pathway.

Belew AT, Meskauskas A, Musalgaonkar S, Advani VM, Sulima SO, Kasprzak WK, Shapiro BA, Dinman JD.

Nature. 2014 Aug 21;512(7514):265-9. doi: 10.1038/nature13429. Epub 2014 Jul 9.


rRNA pseudouridylation defects affect ribosomal ligand binding and translational fidelity from yeast to human cells.

Jack K, Bellodi C, Landry DM, Niederer RO, Meskauskas A, Musalgaonkar S, Kopmar N, Krasnykh O, Dean AM, Thompson SR, Ruggero D, Dinman JD.

Mol Cell. 2011 Nov 18;44(4):660-6. doi: 10.1016/j.molcel.2011.09.017.

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