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Items: 1 to 50 of 382

1.

Morphological heterogeneity among corticogeniculate neurons in ferrets: Quantification and comparison with a previous report in macaque monkeys.

Hasse JM, Bragg EM, Murphy AJ, Briggs F.

J Comp Neurol. 2018 Apr 17. doi: 10.1002/cne.24451. [Epub ahead of print]

PMID:
29664120
2.

Platelets expressing IgG receptor FcγRIIA/CD32A determine the severity of experimental anaphylaxis.

Beutier H, Hechler B, Godon O, Wang Y, Gillis CM, de Chaisemartin L, Gouel-Chéron A, Magnenat S, Macdonald LE, Murphy AJ; NASA study group, Chollet-Martin S, Longrois D, Gachet C, Bruhns P, Jönsson F.

Sci Immunol. 2018 Apr 13;3(22). pii: eaan5997. doi: 10.1126/sciimmunol.aan5997.

PMID:
29654057
3.

Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement.

Orengo JM, Radin AR, Kamat V, Badithe A, Ben LH, Bennett BL, Zhong S, Birchard D, Limnander A, Rafique A, Bautista J, Kostic A, Newell D, Duan X, Franklin MC, Olson W, Huang T, Gandhi NA, Lipsich L, Stahl N, Papadopoulos NJ, Murphy AJ, Yancopoulos GD.

Nat Commun. 2018 Apr 12;9(1):1421. doi: 10.1038/s41467-018-03636-8.

4.

Small non-coding RNAs are altered by short-term sprint interval training in men.

Denham J, Gray AJ, Scott-Hamilton J, Hagstrom AD, Murphy AJ.

Physiol Rep. 2018 Apr;6(7):e13653. doi: 10.14814/phy2.13653.

5.

A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease.

Abul-Husn NS, Cheng X, Li AH, Xin Y, Schurmann C, Stevis P, Liu Y, Kozlitina J, Stender S, Wood GC, Stepanchick AN, Still MD, McCarthy S, O'Dushlaine C, Packer JS, Balasubramanian S, Gosalia N, Esopi D, Kim SY, Mukherjee S, Lopez AE, Fuller ED, Penn J, Chu X, Luo JZ, Mirshahi UL, Carey DJ, Still CD, Feldman MD, Small A, Damrauer SM, Rader DJ, Zambrowicz B, Olson W, Murphy AJ, Borecki IB, Shuldiner AR, Reid JG, Overton JD, Yancopoulos GD, Hobbs HH, Cohen JC, Gottesman O, Teslovich TM, Baras A, Mirshahi T, Gromada J, Dewey FE.

N Engl J Med. 2018 Mar 22;378(12):1096-1106. doi: 10.1056/NEJMoa1712191.

PMID:
29562163
6.

Glucagon contributes to liver zonation.

Cheng X, Kim SY, Okamoto H, Xin Y, Yancopoulos GD, Murphy AJ, Gromada J.

Proc Natl Acad Sci U S A. 2018 Mar 19. pii: 201721403. doi: 10.1073/pnas.1721403115. [Epub ahead of print]

7.

Hand of FATe: lipid metabolism in hematopoietic stem cells.

Lee MKS, Al-Sharea A, Dragoljevic D, Murphy AJ.

Curr Opin Lipidol. 2018 Mar 9. doi: 10.1097/MOL.0000000000000500. [Epub ahead of print]

PMID:
29528857
8.

SGLT2 inhibition reduces atherosclerosis by enhancing lipoprotein clearance in Ldlr-/- type 1 diabetic mice.

Al-Sharea A, Murphy AJ, Huggins LA, Hu Y, Goldberg IJ, Nagareddy PR.

Atherosclerosis. 2018 Apr;271:166-176. doi: 10.1016/j.atherosclerosis.2018.02.028. Epub 2018 Mar 2.

PMID:
29518749
9.

Biology and function of adipose tissue macrophages, dendritic cells and B cells.

Ivanov S, Merlin J, Lee MKS, Murphy AJ, Guinamard RR.

Atherosclerosis. 2018 Apr;271:102-110. doi: 10.1016/j.atherosclerosis.2018.01.018. Epub 2018 Feb 20. Review.

PMID:
29482037
10.

Delta-like Ligand-4-Notch Signaling Inhibition Regulates Pancreatic Islet Function and Insulin Secretion.

Billiard F, Karaliota S, Wang B, Stellas D, Serafimidis I, Manousopoulou A, Koutmani Y, Ninou E, Golubov J, DaNave A, Tsakanikas P, Xin Y, Zhang W, Sleeman M, Yancopoulos GD, Murphy AJ, Garbis SD, Karalis K, Skokos D.

Cell Rep. 2018 Jan 23;22(4):895-904. doi: 10.1016/j.celrep.2017.12.076. Epub 2018 Jan 28.

11.

Leptin-deficient obesity prolongs survival in a murine model of myelodysplastic syndrome.

Kraakman MJ, Kammoun HL, Dragoljevic D, Al-Sharea A, Lee MKS, Flynn MC, Stolz CJ, Guirguis AA, Lancaster GI, Chin-Dusting J, Curtis DJ, Murphy AJ.

Haematologica. 2018 Apr;103(4):597-606. doi: 10.3324/haematol.2017.181958. Epub 2018 Jan 25.

12.

Lipoprotein Lipase Deficiency Impairs Bone Marrow Myelopoiesis and Reduces Circulating Monocyte Levels.

Chang CL, Garcia-Arcos I, Nyrén R, Olivecrona G, Kim JY, Hu Y, Agrawal RR, Murphy AJ, Goldberg IJ, Deckelbaum RJ.

Arterioscler Thromb Vasc Biol. 2018 Mar;38(3):509-519. doi: 10.1161/ATVBAHA.117.310607. Epub 2018 Jan 25.

PMID:
29371243
13.

Y-chromosome lineage determines cardiovascular organ T-cell infiltration in the stroke-prone spontaneously hypertensive rat.

Khan SI, Andrews KL, Jackson KL, Memon B, Jefferis AM, Lee MKS, Diep H, Wei Z, Drummond GR, Head GA, Jennings GL, Murphy AJ, Vinh A, Sampson AK, Chin-Dusting JPF.

FASEB J. 2018 Jan 8:fj201700933RR. doi: 10.1096/fj.201700933RR. [Epub ahead of print]

PMID:
29301944
14.

Take me to the liver: adipose tissue macrophages coordinate hepatic neutrophil recruitment.

Pernes G, Lancaster GI, Murphy AJ.

Gut. 2018 Jan 3. pii: gutjnl-2017-315393. doi: 10.1136/gutjnl-2017-315393. [Epub ahead of print] No abstract available.

PMID:
29298875
15.

Endogenous Annexin-A1 Regulates Haematopoietic Stem Cell Mobilisation and Inflammatory Response Post Myocardial Infarction in Mice In Vivo.

Qin CX, Finlayson SB, Ai-Sharea A, Tate M, De Blasio MJ, Deo M, Rosli S, Prakoso D, Thomas CJ, Kiriazis H, Gould E, Yang YH, Morand EF, Perretti M, Murphy AJ, Du XJ, Gao XM, Ritchie RH.

Sci Rep. 2017 Nov 30;7(1):16615. doi: 10.1038/s41598-017-16317-1.

16.

Sugar or Fat?-Metabolic Requirements for Immunity to Viral Infections.

Shehata HM, Murphy AJ, Lee MKS, Gardiner CM, Crowe SM, Sanjabi S, Finlay DK, Palmer CS.

Front Immunol. 2017 Oct 16;8:1311. doi: 10.3389/fimmu.2017.01311. eCollection 2017. Review.

17.

Humanized mouse model supports development, function, and tissue residency of human natural killer cells.

Herndler-Brandstetter D, Shan L, Yao Y, Stecher C, Plajer V, Lietzenmayer M, Strowig T, de Zoete MR, Palm NW, Chen J, Blish CA, Frleta D, Gurer C, Macdonald LE, Murphy AJ, Yancopoulos GD, Montgomery RR, Flavell RA.

Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9626-E9634. doi: 10.1073/pnas.1705301114. Epub 2017 Oct 25.

PMID:
29078283
18.

Pyloric stenosis: an enigma more than a century after the first successful treatment.

El-Gohary Y, Abdelhafeez A, Paton E, Gosain A, Murphy AJ.

Pediatr Surg Int. 2018 Jan;34(1):21-27. doi: 10.1007/s00383-017-4196-y. Epub 2017 Oct 13. Review.

PMID:
29030700
19.

Diabetes-mediated myelopoiesis and the relationship to cardiovascular risk.

Barrett TJ, Murphy AJ, Goldberg IJ, Fisher EA.

Ann N Y Acad Sci. 2017 Aug;1402(1):31-42. doi: 10.1111/nyas.13462. Review.

PMID:
28926114
20.

The function of Drosophila larval class IV dendritic arborization sensory neurons in the larval-pupal transition is separable from their function in mechanical nociception responses.

Brown HE, Desai T, Murphy AJ, Pancholi H, Schmidt ZW, Swahn H, Liebl EC.

PLoS One. 2017 Sep 14;12(9):e0184950. doi: 10.1371/journal.pone.0184950. eCollection 2017.

21.

The Endless Summer: Thermoneutrality Prevents Monocytosis and Reduces Atherosclerosis.

Woollard KJ, Murphy AJ.

Circ Res. 2017 Sep 1;121(6):596-598. doi: 10.1161/CIRCRESAHA.117.311721. No abstract available.

22.

Nicotinic acetylcholine receptor alpha 7 stimulation dampens splenic myelopoiesis and inhibits atherogenesis in Apoe-/- mice.

Al-Sharea A, Lee MKS, Whillas A, Flynn MC, Chin-Dusting J, Murphy AJ.

Atherosclerosis. 2017 Oct;265:47-53. doi: 10.1016/j.atherosclerosis.2017.08.010. Epub 2017 Aug 18.

PMID:
28858686
23.

Assessment of metabolic and mitochondrial dynamics in CD4+ and CD8+ T cells in virologically suppressed HIV-positive individuals on combination antiretroviral therapy.

Masson JJR, Murphy AJ, Lee MKS, Ostrowski M, Crowe SM, Palmer CS.

PLoS One. 2017 Aug 30;12(8):e0183931. doi: 10.1371/journal.pone.0183931. eCollection 2017.

24.

Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by Porphyromonas gingivalis and Its Outer Membrane Vesicles.

Fleetwood AJ, Lee MKS, Singleton W, Achuthan A, Lee MC, O'Brien-Simpson NM, Cook AD, Murphy AJ, Dashper SG, Reynolds EC, Hamilton JA.

Front Cell Infect Microbiol. 2017 Aug 4;7:351. doi: 10.3389/fcimb.2017.00351. eCollection 2017.

25.

The Expansion of Heterotopic Bone in Fibrodysplasia Ossificans Progressiva Is Activin A-Dependent.

Upadhyay J, Xie L, Huang L, Das N, Stewart RC, Lyon MC, Palmer K, Rajamani S, Graul C, Lobo M, Wellman TJ, Soares EJ, Silva MD, Hesterman J, Wang L, Wen X, Qian X, Nannuru K, Idone V, Murphy AJ, Economides AN, Hatsell SJ.

J Bone Miner Res. 2017 Dec;32(12):2489-2499. doi: 10.1002/jbmr.3235. Epub 2017 Sep 22.

PMID:
28782882
26.

Visual speed sensitivity in the drum corps color guard.

Matthews N, Welch L, Coplin FD, Murphy AJ, Puritz MR.

J Vis. 2017 Jul 1;17(8):7. doi: 10.1167/17.8.7.

PMID:
28692725
27.

TRAK2, a novel regulator of ABCA1 expression, cholesterol efflux and HDL biogenesis.

Lake NJ, Taylor RL, Trahair H, Harikrishnan KN, Curran JE, Almeida M, Kulkarni H, Mukhamedova N, Hoang A, Low H, Murphy AJ, Johnson MP, Dyer TD, Mahaney MC, Göring HHH, Moses EK, Sviridov D, Blangero J, Jowett JBM, Bozaoglu K.

Eur Heart J. 2017 Dec 21;38(48):3579-3587. doi: 10.1093/eurheartj/ehx315.

PMID:
28655204
28.

Amino Acid Transporter Slc38a5 Controls Glucagon Receptor Inhibition-Induced Pancreatic α Cell Hyperplasia in Mice.

Kim J, Okamoto H, Huang Z, Anguiano G, Chen S, Liu Q, Cavino K, Xin Y, Na E, Hamid R, Lee J, Zambrowicz B, Unger R, Murphy AJ, Xu Y, Yancopoulos GD, Li WH, Gromada J.

Cell Metab. 2017 Jun 6;25(6):1348-1361.e8. doi: 10.1016/j.cmet.2017.05.006.

PMID:
28591637
29.

The relationship between lower body stiffness and injury incidence in female netballers.

Pickering Rodriguez EC, Watsford ML, Bower RG, Murphy AJ.

Sports Biomech. 2017 Sep;16(3):361-373. doi: 10.1080/14763141.2017.1319970. Epub 2017 May 29.

PMID:
28553879
30.

Expression of receptor-type protein tyrosine phosphatase in developing and adult renal vasculature.

Takahashi K, Kim R, Lauhan C, Park Y, Nguyen NG, Vestweber D, Dominguez MG, Valenzuela DM, Murphy AJ, Yancopoulos GD, Gale NW, Takahashi T.

PLoS One. 2017 May 25;12(5):e0177192. doi: 10.1371/journal.pone.0177192. eCollection 2017.

31.

Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease.

Dewey FE, Gusarova V, Dunbar RL, O'Dushlaine C, Schurmann C, Gottesman O, McCarthy S, Van Hout CV, Bruse S, Dansky HM, Leader JB, Murray MF, Ritchie MD, Kirchner HL, Habegger L, Lopez A, Penn J, Zhao A, Shao W, Stahl N, Murphy AJ, Hamon S, Bouzelmat A, Zhang R, Shumel B, Pordy R, Gipe D, Herman GA, Sheu WHH, Lee IT, Liang KW, Guo X, Rotter JI, Chen YI, Kraus WE, Shah SH, Damrauer S, Small A, Rader DJ, Wulff AB, Nordestgaard BG, Tybjærg-Hansen A, van den Hoek AM, Princen HMG, Ledbetter DH, Carey DJ, Overton JD, Reid JG, Sasiela WJ, Banerjee P, Shuldiner AR, Borecki IB, Teslovich TM, Yancopoulos GD, Mellis SJ, Gromada J, Baras A.

N Engl J Med. 2017 Jul 20;377(3):211-221. doi: 10.1056/NEJMoa1612790. Epub 2017 May 24.

32.

Neutrophil-derived S100 calcium-binding proteins A8/A9 promote reticulated thrombocytosis and atherogenesis in diabetes.

Kraakman MJ, Lee MK, Al-Sharea A, Dragoljevic D, Barrett TJ, Montenont E, Basu D, Heywood S, Kammoun HL, Flynn M, Whillas A, Hanssen NM, Febbraio MA, Westein E, Fisher EA, Chin-Dusting J, Cooper ME, Berger JS, Goldberg IJ, Nagareddy PR, Murphy AJ.

J Clin Invest. 2017 Jun 1;127(6):2133-2147. doi: 10.1172/JCI92450. Epub 2017 May 15.

33.

Plasma metabolite profiles, cellular cholesterol efflux, and non-traditional cardiovascular risk in patients with CKD.

Ganda A, Yvan-Charvet L, Zhang Y, Lai EJ, Regunathan-Shenk R, Hussain FN, Avasare R, Chakraborty B, Febus AJ, Vernocchi L, Lantigua R, Wang Y, Shi X, Hsieh J, Murphy AJ, Wang N, Bijl N, Gordon KM, de Miguel MH, Singer JR, Hogan J, Cremers S, Magnusson M, Melander O, Gerszten RE, Tall AR.

J Mol Cell Cardiol. 2017 Nov;112:114-122. doi: 10.1016/j.yjmcc.2017.05.001. Epub 2017 May 4.

PMID:
28478047
34.

Activin A more prominently regulates muscle mass in primates than does GDF8.

Latres E, Mastaitis J, Fury W, Miloscio L, Trejos J, Pangilinan J, Okamoto H, Cavino K, Na E, Papatheodorou A, Willer T, Bai Y, Hae Kim J, Rafique A, Jaspers S, Stitt T, Murphy AJ, Yancopoulos GD, Gromada J.

Nat Commun. 2017 Apr 28;8:15153. doi: 10.1038/ncomms15153.

35.

A Clinical Perspective of Anti-Fibrotic Therapies for Cardiovascular Disease.

Fang L, Murphy AJ, Dart AM.

Front Pharmacol. 2017 Apr 6;8:186. doi: 10.3389/fphar.2017.00186. eCollection 2017. Review.

36.

ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance.

Haller JF, Mintah IJ, Shihanian LM, Stevis P, Buckler D, Alexa-Braun CA, Kleiner S, Banfi S, Cohen JC, Hobbs HH, Yancopoulos GD, Murphy AJ, Gusarova V, Gromada J.

J Lipid Res. 2017 Jun;58(6):1166-1173. doi: 10.1194/jlr.M075689. Epub 2017 Apr 15.

PMID:
28413163
37.

The iPSC Awakens ANGPTL3 in Tangier Disease.

Lee MKS, Murphy AJ.

EBioMedicine. 2017 Apr;18:15-16. doi: 10.1016/j.ebiom.2017.04.004. Epub 2017 Apr 4. No abstract available.

38.

Resolution of glucose intolerance in long-term high-fat, high-sucrose-fed mice.

Kowalski GM, Kraakman MJ, Mason SA, Murphy AJ, Bruce CR.

J Endocrinol. 2017 Jun;233(3):269-279. doi: 10.1530/JOE-17-0004. Epub 2017 Mar 30.

PMID:
28360081
39.

Effects of dyslipidaemia on monocyte production and function in cardiovascular disease.

Rahman MS, Murphy AJ, Woollard KJ.

Nat Rev Cardiol. 2017 Jul;14(7):387-400. doi: 10.1038/nrcardio.2017.34. Epub 2017 Mar 16. Review.

40.

Shear-sensitive nanocapsule drug release for site-specific inhibition of occlusive thrombus formation.

Molloy CP, Yao Y, Kammoun H, Bonnard T, Hoefer T, Alt K, Tovar-Lopez F, Rosengarten G, Ramsland PA, van der Meer AD, van den Berg A, Murphy AJ, Hagemeyer CE, Peter K, Westein E.

J Thromb Haemost. 2017 May;15(5):972-982. doi: 10.1111/jth.13666. Epub 2017 Apr 9.

PMID:
28267256
41.

Inhibition of the Renin-Angiotensin System Post Myocardial Infarction Prevents Inflammation-Associated Acute Cardiac Rupture.

Gao XM, Tsai A, Al-Sharea A, Su Y, Moore S, Han LP, Kiriazis H, Dart AM, Murphy AJ, Du XJ.

Cardiovasc Drugs Ther. 2017 Apr;31(2):145-156. doi: 10.1007/s10557-017-6717-2.

PMID:
28204966
42.

ANGPTL8 Blockade With a Monoclonal Antibody Promotes Triglyceride Clearance, Energy Expenditure, and Weight Loss in Mice.

Gusarova V, Banfi S, Alexa-Braun CA, Shihanian LM, Mintah IJ, Lee JS, Xin Y, Su Q, Kamat V, Cohen JC, Hobbs HH, Zambrowicz B, Yancopoulos GD, Murphy AJ, Gromada J.

Endocrinology. 2017 May 1;158(5):1252-1259. doi: 10.1210/en.2016-1894.

PMID:
28204173
43.

Angptl4 does not control hyperglucagonemia or α-cell hyperplasia following glucagon receptor inhibition.

Okamoto H, Cavino K, Na E, Krumm E, Kim S, Stevis PE, Harp J, Murphy AJ, Yancopoulos GD, Gromada J.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2747-2752. doi: 10.1073/pnas.1620989114. Epub 2017 Jan 31.

44.

Glucagon receptor inhibition normalizes blood glucose in severe insulin-resistant mice.

Okamoto H, Cavino K, Na E, Krumm E, Kim SY, Cheng X, Murphy AJ, Yancopoulos GD, Gromada J.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2753-2758. doi: 10.1073/pnas.1621069114. Epub 2017 Jan 23.

45.

A novel humanized mouse model with significant improvement of class-switched, antigen-specific antibody production.

Yu H, Borsotti C, Schickel JN, Zhu S, Strowig T, Eynon EE, Frleta D, Gurer C, Murphy AJ, Yancopoulos GD, Meffre E, Manz MG, Flavell RA.

Blood. 2017 Feb 23;129(8):959-969. doi: 10.1182/blood-2016-04-709584. Epub 2017 Jan 11.

46.

Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice.

Wiehe K, Nicely NI, Lockwood B, Kuraoka M, Anasti K, Arora S, Bowman CM, Stolarchuk C, Parks R, Lloyd KE, Xia SM, Duffy R, Shen X, Kyratsous CA, Macdonald LE, Murphy AJ, Scearce RM, Moody MA, Alam SM, Verkoczy L, Tomaras GD, Kelsoe G, Haynes BF.

J Immunol. 2017 Feb 1;198(3):1047-1055. doi: 10.4049/jimmunol.1601640. Epub 2016 Dec 23.

47.

A comparison study between the saturation-recovery-T1 and CASL MRI methods for quantitative CBF imaging.

Wang X, Zhu XH, Zhang Y, Divani AA, Murphy AJ, Chen W.

Magn Reson Imaging. 2017 Apr;37:179-186. doi: 10.1016/j.mri.2016.11.022. Epub 2016 Dec 2.

48.

Peritoneal Malignancy in Children: A Pictorial Review.

James KM, Bogue CO, Murphy AJ, Navarro OM.

Can Assoc Radiol J. 2016 Nov;67(4):402-408. doi: 10.1016/j.carj.2016.03.003. Epub 2016 Aug 11. Review.

PMID:
27523447
49.

ANGPTL4-αvβ3 interaction counteracts hypoxia-induced vascular permeability by modulating Src signalling downstream of vascular endothelial growth factor receptor 2.

Gomez Perdiguero E, Liabotis-Fontugne A, Durand M, Faye C, Ricard-Blum S, Simonutti M, Augustin S, Robb BM, Paques M, Valenzuela DM, Murphy AJ, Yancopoulos GD, Thurston G, Galaup A, Monnot C, Germain S.

J Pathol. 2016 Dec;240(4):461-471. doi: 10.1002/path.4805. Epub 2016 Oct 21.

PMID:
27577973
50.

In vivo effector functions of high-affinity mouse IgG receptor FcγRI in disease and therapy models.

Gillis CM, Zenatti PP, Mancardi DA, Beutier H, Fiette L, Macdonald LE, Murphy AJ, Celli S, Bousso P, Jönsson F, Bruhns P.

J Autoimmun. 2017 Jun;80:95-102. doi: 10.1016/j.jaut.2016.09.009. Epub 2016 Oct 10.

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