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NF1 mutations in conjunctival melanoma.

Scholz SL, Cosgarea I, Süßkind D, Murali R, Möller I, Reis H, Leonardelli S, Schilling B, Schimming T, Hadaschik E, Franklin C, Paschen A, Sucker A, Steuhl KP, Schadendorf D, Westekemper H, Griewank KG.

Br J Cancer. 2018 Mar 21. doi: 10.1038/s41416-018-0046-5. [Epub ahead of print]


NTRK Fusions Define a Novel Uterine Sarcoma Subtype With Features of Fibrosarcoma.

Chiang S, Cotzia P, Hyman DM, Drilon A, Tap WD, Zhang L, Hechtman JF, Frosina D, Jungbluth AA, Murali R, Park KJ, Soslow RA, Oliva E, Iafrate AJ, Benayed R, Ladanyi M, Antonescu CR.

Am J Surg Pathol. 2018 Mar 16. doi: 10.1097/PAS.0000000000001055. [Epub ahead of print]


Transducin-Like Enhancer of Split 3 (TLE3) expression is associated with taxane sensitivity in non-serous ovarian carcinoma in a three-cohort study.

Ring BZ, Murali R, Soslow RA, Bowtell DDL, Fereday S, DeFazio A, Traficante N, Kennedy CJ, Brand A, Sharma R, Harnett P, Samimi G.

Cancer Epidemiol Biomarkers Prev. 2018 Mar 12. pii: cebp.1101.2017. doi: 10.1158/1055-9965.EPI-17-1101. [Epub ahead of print]


GNA11 Q209L Mouse Model Reveals RasGRP3 as an Essential Signaling Node in Uveal Melanoma.

Moore AR, Ran L, Guan Y, Sher JJ, Hitchman TD, Zhang JQ, Hwang C, Walzak EG, Shoushtari AN, Monette S, Murali R, Wiesner T, Griewank KG, Chi P, Chen Y.

Cell Rep. 2018 Feb 27;22(9):2455-2468. doi: 10.1016/j.celrep.2018.01.081.


Evolving Roles of Histologic Evaluation and Molecular/Genomic Profiling in the Management of Endometrial Cancer.

Murali R, Delair DF, Bean SM, Abu-Rustum NR, Soslow RA.

J Natl Compr Canc Netw. 2018 Feb;16(2):201-209. doi: 10.6004/jnccn.2017.7066. Review.


HER kinase inhibition in patients with HER2- and HER3-mutant cancers.

Hyman DM, Piha-Paul SA, Won H, Rodon J, Saura C, Shapiro GI, Juric D, Quinn DI, Moreno V, Doger B, Mayer IA, Boni V, Calvo E, Loi S, Lockhart AC, Erinjeri JP, Scaltriti M, Ulaner GA, Patel J, Tang J, Beer H, Selcuklu SD, Hanrahan AJ, Bouvier N, Melcer M, Murali R, Schram AM, Smyth LM, Jhaveri K, Li BT, Drilon A, Harding JJ, Iyer G, Taylor BS, Berger MF, Cutler RE Jr, Xu F, Butturini A, Eli LD, Mann G, Farrell C, Lalani AS, Bryce RP, Arteaga CL, Meric-Bernstam F, Baselga J, Solit DB.

Nature. 2018 Feb 8;554(7691):189-194. doi: 10.1038/nature25475. Epub 2018 Jan 31.


A guided tour of selected issues pertaining to metastatic carcinomas involving or originating from the gynecologic tract.

Soslow RA, Murali R.

Semin Diagn Pathol. 2018 Mar;35(2):95-107. doi: 10.1053/j.semdp.2017.11.007. Epub 2017 Nov 20. Review. No abstract available.


ZC3H7B-BCOR high-grade endometrial stromal sarcomas: a report of 17 cases of a newly defined entity.

Lewis N, Soslow RA, Delair DF, Park KJ, Murali R, Hollmann TJ, Davidson B, Micci F, Panagopoulos I, Hoang LN, Arias-Stella JA 3rd, Oliva E, Young RH, Hensley ML, Leitao MM Jr, Hameed M, Benayed R, Ladanyi M, Frosina D, Jungbluth AA, Antonescu CR, Chiang S.

Mod Pathol. 2017 Dec 1. doi: 10.1038/modpathol.2017.162. [Epub ahead of print]


The roles of pathology in targeted therapy of women with gynecologic cancers.

Murali R, Grisham RN, Soslow RA.

Gynecol Oncol. 2018 Jan;148(1):213-221. doi: 10.1016/j.ygyno.2017.11.020. Epub 2017 Nov 23. Review.


Atypical fibroxanthoma and pleomorphic dermal sarcoma harbor frequent NOTCH1/2 and FAT1 mutations and similar DNA copy number alteration profiles.

Griewank KG, Wiesner T, Murali R, Pischler C, Müller H, Koelsche C, Möller I, Franklin C, Cosgarea I, Sucker A, Schadendorf D, Schaller J, Horn S, Brenn T, Mentzel T.

Mod Pathol. 2018 Mar;31(3):418-428. doi: 10.1038/modpathol.2017.146. Epub 2017 Nov 3.


Deletion of 3p13-14 locus spanning FOXP1 to SHQ1 cooperates with PTEN loss in prostate oncogenesis.

Hieronymus H, Iaquinta PJ, Wongvipat J, Gopalan A, Murali R, Mao N, Carver BS, Sawyers CL.

Nat Commun. 2017 Oct 20;8(1):1081. doi: 10.1038/s41467-017-01198-9.


A prediction tool incorporating the biomarker S-100B for patient selection for completion lymph node dissection in stage III melanoma.

Damude S, Wevers KP, Murali R, Kruijff S, Hoekstra HJ, Bastiaannet E.

Eur J Surg Oncol. 2017 Sep;43(9):1753-1759. doi: 10.1016/j.ejso.2017.07.006. Epub 2017 Jul 29.


Diverse BRCA1 and BRCA2 Reversion Mutations in Circulating Cell-Free DNA of Therapy-Resistant Breast or Ovarian Cancer.

Weigelt B, Comino-Méndez I, de Bruijn I, Tian L, Meisel JL, García-Murillas I, Fribbens C, Cutts R, Martelotto LG, Ng CKY, Lim RS, Selenica P, Piscuoglio S, Aghajanian C, Norton L, Murali R, Hyman DM, Borsu L, Arcila ME, Konner J, Reis-Filho JS, Greenberg RA, Robson ME, Turner NC.

Clin Cancer Res. 2017 Nov 1;23(21):6708-6720. doi: 10.1158/1078-0432.CCR-17-0544. Epub 2017 Aug 1.


In-vitro maturation in women with polycystic ovaries and high anti-Müllerian hormone levels.

Gunasheela D, Murali R, Menon JG, Hiremath N, Son WY.

Minerva Ginecol. 2018 Feb;70(1):120-121. doi: 10.23736/S0026-4784.17.04057-6. Epub 2017 Jul 27. No abstract available.


Frequent GNAQ, GNA11, and EIF1AX Mutations in Iris Melanoma.

Scholz SL, Möller I, Reis H, Süßkind D, van de Nes JAP, Leonardelli S, Schilling B, Livingstone E, Schimming T, Paschen A, Sucker A, Murali R, Steuhl KP, Schadendorf D, Westekemper H, Griewank KG.

Invest Ophthalmol Vis Sci. 2017 Jul 1;58(9):3464-3470. doi: 10.1167/iovs.17-21838.


The intra-articular injection of RANKL-binding peptides inhibits cartilage degeneration in a murine model of osteoarthritis.

Haque Bhuyan MZ, Tamura Y, Sone E, Yoshinari Y, Maeda C, Takahashi M, Tabata Y, Murali R, Waki Y, Aoki K.

J Pharmacol Sci. 2017 Jun;134(2):124-130. doi: 10.1016/j.jphs.2017.05.008. Epub 2017 Jun 13.


Optical Characteristics and Tumor Imaging Capabilities of Near Infrared Dyes in Free and Nano-Encapsulated Formulations Comprised of Viral Capsids.

Guerrero Y, Singh SP, Mai T, Murali RK, Tanikella L, Zahedi A, Kundra V, Anvari B.

ACS Appl Mater Interfaces. 2017 Jun 14;9(23):19601-19611. doi: 10.1021/acsami.7b03373. Epub 2017 May 31.


Activating CYSLTR2 and PLCB4 Mutations in Primary Leptomeningeal Melanocytic Tumors.

van de Nes JAP, Koelsche C, Gessi M, Möller I, Sucker A, Scolyer RA, Buckland ME, Pietsch T, Murali R, Schadendorf D, Griewank KG.

J Invest Dermatol. 2017 Sep;137(9):2033-2035. doi: 10.1016/j.jid.2017.04.022. Epub 2017 May 10. No abstract available.


Genetic analysis of a morphologically heterogeneous ovarian endometrioid carcinoma.

Geyer FC, Pareja F, Burke KA, Schultheis AM, Hussein YR, Ye J, De Filippo MR, Marchio C, Macedo GS, Piscuoglio S, Lim RS, Toy E, Murali R, Jungbluth AA, Reis-Filho JS, Soslow RA, Weigelt B.

Histopathology. 2017 Sep;71(3):480-487. doi: 10.1111/his.13240. Epub 2017 Jun 16.


Direct Antimicrobial Activity of IFN-β.

Kaplan A, Lee MW, Wolf AJ, Limon JJ, Becker CA, Ding M, Murali R, Lee EY, Liu GY, Wong GCL, Underhill DM.

J Immunol. 2017 May 15;198(10):4036-4045. doi: 10.4049/jimmunol.1601226. Epub 2017 Apr 14.


SF3B1 and BAP1 mutations in blue nevus-like melanoma.

Griewank KG, Müller H, Jackett LA, Emberger M, Möller I, van de Nes JA, Zimmer L, Livingstone E, Wiesner T, Scholz SL, Cosgarea I, Sucker A, Schimming T, Hillen U, Schilling B, Paschen A, Reis H, Mentzel T, Kutzner H, Rütten A, Murali R, Scolyer RA, Schadendorf D.

Mod Pathol. 2017 Jul;30(7):928-939. doi: 10.1038/modpathol.2017.23. Epub 2017 Apr 14.


Discrete signaling mechanisms of mTORC1 and mTORC2: Connected yet apart in cellular and molecular aspects.

Jhanwar-Uniyal M, Amin AG, Cooper JB, Das K, Schmidt MH, Murali R.

Adv Biol Regul. 2017 May;64:39-48. doi: 10.1016/j.jbior.2016.12.001. Epub 2017 Jan 4. Review.


Yes1 signaling mediates the resistance to Trastuzumab/Lap atinib in breast cancer.

Takeda T, Yamamoto H, Kanzaki H, Suzawa K, Yoshioka T, Tomida S, Cui X, Murali R, Namba K, Sato H, Torigoe H, Watanabe M, Shien K, Soh J, Asano H, Tsukuda K, Kitamura Y, Miyoshi S, Sendo T, Toyooka S.

PLoS One. 2017 Feb 3;12(2):e0171356. doi: 10.1371/journal.pone.0171356. eCollection 2017. Erratum in: PLoS One. 2017 Mar 16;12 (3):e0174493.


Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6.

Lai KKY, Kweon SM, Chi F, Hwang E, Kabe Y, Higashiyama R, Qin L, Yan R, Wu RP, Lai K, Fujii N, French S, Xu J, Wang JY, Murali R, Mishra L, Lee JS, Ntambi JM, Tsukamoto H.

Gastroenterology. 2017 May;152(6):1477-1491. doi: 10.1053/j.gastro.2017.01.021. Epub 2017 Jan 29.


A Comparative Study of Three Different Types of Stem Cells for Treatment of Rat Spinal Cord Injury.

Ruzicka J, Machova-Urdzikova L, Gillick J, Amemori T, Romanyuk N, Karova K, Zaviskova K, Dubisova J, Kubinova S, Murali R, Sykova E, Jhanwar-Uniyal M, Jendelova P.

Cell Transplant. 2017 Apr 13;26(4):585-603. doi: 10.3727/096368916X693671. Epub 2016 Nov 2.


Activating cysteinyl leukotriene receptor 2 (CYSLTR2) mutations in blue nevi.

Möller I, Murali R, Müller H, Wiesner T, Jackett LA, Scholz SL, Cosgarea I, van de Nes JA, Sucker A, Hillen U, Schilling B, Paschen A, Kutzner H, Rütten A, Böckers M, Scolyer RA, Schadendorf D, Griewank KG.

Mod Pathol. 2017 Mar;30(3):350-356. doi: 10.1038/modpathol.2016.201. Epub 2016 Dec 9.


The role of cancer stem cells in tumor heterogeneity and resistance to therapy.

Konrad CV, Murali R, Varghese BA, Nair R.

Can J Physiol Pharmacol. 2017 Jan;95(1):1-15. doi: 10.1139/cjpp-2016-0079. Epub 2016 Sep 3. Review.


HER2-positive breast cancer targeting and treatment by a peptide-conjugated mini nanodrug.

Ding H, Gangalum PR, Galstyan A, Fox I, Patil R, Hubbard P, Murali R, Ljubimova JY, Holler E.

Nanomedicine. 2017 Feb;13(2):631-639. doi: 10.1016/j.nano.2016.07.013. Epub 2016 Aug 9.


RNASeq analysis reveals biological processes governing the clinical behaviour of endometrioid and serous endometrial cancers.

Lemetre C, Vieites B, Ng CK, Piscuoglio S, Schultheis AM, Marchiò C, Murali R, Lopez-García MA, Palacios JC, Jungbluth AA, Terracciano LM, Reis-Filho JS, Weigelt B.

Eur J Cancer. 2016 Sep;64:149-58. doi: 10.1016/j.ejca.2016.05.028. Epub 2016 Jul 14.


Peptide drugs accelerate BMP-2-induced calvarial bone regeneration and stimulate osteoblast differentiation through mTORC1 signaling.

Sugamori Y, Mise-Omata S, Maeda C, Aoki S, Tabata Y, Murali R, Yasuda H, Udagawa N, Suzuki H, Honma M, Aoki K.

Bioessays. 2016 Aug;38(8):717-25. doi: 10.1002/bies.201600104. Epub 2016 Jun 27.


Successful Treatment of Complex Regional Pain Syndrome with Pseudoaneurysm Excision and Median Nerve Neurolysis.

Gillick JL, Cooper JB, Babu S, Das K, Murali R.

World Neurosurg. 2016 Aug;92:582.e5-8. doi: 10.1016/j.wneu.2016.06.023. Epub 2016 Jun 16.


Peptide-induced de novo bone formation after tooth extraction prevents alveolar bone loss in a murine tooth extraction model.

Arai Y, Aoki K, Shimizu Y, Tabata Y, Ono T, Murali R, Mise-Omata S, Wakabayashi N.

Eur J Pharmacol. 2016 Jul 5;782:89-97. doi: 10.1016/j.ejphar.2016.04.049. Epub 2016 Apr 23.


Squamous precursor lesions of the vulva: current classification and diagnostic challenges.

Hoang LN, Park KJ, Soslow RA, Murali R.

Pathology. 2016 Jun;48(4):291-302. doi: 10.1016/j.pathol.2016.02.015. Epub 2016 Apr 23. Review.


Diagnosing a Primary Leptomeningeal Melanoma by Gene Mutation Signature.

van de Nes J, Wrede K, Ringelstein A, Stiller M, Horn S, Sucker A, Möller I, Scholz SL, Murali R, Gessi M, Schadendorf D, Griewank KG.

J Invest Dermatol. 2016 Jul;136(7):1526-1528. doi: 10.1016/j.jid.2016.03.031. Epub 2016 Apr 7. No abstract available.


Genomic aberrations in spitzoid melanocytic tumours and their implications for diagnosis, prognosis and therapy.

Wiesner T, Kutzner H, Cerroni L, Mihm MC Jr, Busam KJ, Murali R.

Pathology. 2016 Feb;48(2):113-31. doi: 10.1016/j.pathol.2015.12.007. Epub 2016 Jan 18. Review.


Delivery of RANKL-Binding Peptide OP3-4 Promotes BMP-2-Induced Maxillary Bone Regeneration.

Uehara T, Mise-Omata S, Matsui M, Tabata Y, Murali R, Miyashin M, Aoki K.

J Dent Res. 2016 Jun;95(6):665-72. doi: 10.1177/0022034516633170. Epub 2016 Mar 22.


Principal component analysis of MALDI TOF MS mass spectra separates M. abscessus (sensu stricto) from M. massiliense isolates.

Kehrmann J, Wessel S, Murali R, Hampel A, Bange FC, Buer J, Mosel F.

BMC Microbiol. 2016 Mar 1;16:24. doi: 10.1186/s12866-016-0636-4.


Trastuzumab-Resistant Luminal B Breast Cancer Cells Show Basal-Like Cell Growth Features Through NF-κB-Activation.

Kanzaki H, Mukhopadhya NK, Cui X, Ramanujan VK, Murali R.

Monoclon Antib Immunodiagn Immunother. 2016 Feb;35(1):1-11. doi: 10.1089/mab.2015.0056. Epub 2016 Jan 21.


Molecular Pathways Mediating Metastases to the Brain via Epithelial-to-Mesenchymal Transition: Genes, Proteins, and Functional Analysis.

Jeevan DS, Cooper JB, Braun A, Murali R, Jhanwar-Uniyal M.

Anticancer Res. 2016 Feb;36(2):523-32.


Targeted next generation sequencing reveals unique mutation profile of primary melanocytic tumors of the central nervous system.

van de Nes J, Gessi M, Sucker A, Möller I, Stiller M, Horn S, Scholz SL, Pischler C, Stadtler N, Schilling B, Zimmer L, Hillen U, Scolyer RA, Buckland ME, Lauriola L, Pietsch T, Waha A, Schadendorf D, Murali R, Griewank KG.

J Neurooncol. 2016 May;127(3):435-44. doi: 10.1007/s11060-015-2052-2. Epub 2016 Jan 7.


The Anti-Inflammatory Compound Curcumin Enhances Locomotor and Sensory Recovery after Spinal Cord Injury in Rats by Immunomodulation.

Machova Urdzikova L, Karova K, Ruzicka J, Kloudova A, Shannon C, Dubisova J, Murali R, Kubinova S, Sykova E, Jhanwar-Uniyal M, Jendelova P.

Int J Mol Sci. 2015 Dec 31;17(1). pii: E49. doi: 10.3390/ijms17010049.


ATP-site binding inhibitor effectively targets mTORC1 and mTORC2 complexes in glioblastoma.

Neil J, Shannon C, Mohan A, Laurent D, Murali R, Jhanwar-Uniyal M.

Int J Oncol. 2016 Mar;48(3):1045-52. doi: 10.3892/ijo.2015.3311. Epub 2015 Dec 28.


Highly biocompatible collagen-Delonix regia seed polysaccharide hybrid scaffolds for antimicrobial wound dressing.

Cheirmadurai K, Thanikaivelan P, Murali R.

Carbohydr Polym. 2016 Feb 10;137:584-593. doi: 10.1016/j.carbpol.2015.11.015. Epub 2015 Nov 10.


Group B Streptococcus Evades Host Immunity by Degrading Hyaluronan.

Kolar SL, Kyme P, Tseng CW, Soliman A, Kaplan A, Liang J, Nizet V, Jiang D, Murali R, Arditi M, Underhill DM, Liu GY.

Cell Host Microbe. 2015 Dec 9;18(6):694-704. doi: 10.1016/j.chom.2015.11.001.


Metastatic Renal Cell Carcinoma Mimicking Trigeminal Schwannoma in a Patient Presenting with Trigeminal Neuralgia.

Wang A, Kleinman G, Murali R, Wainwright J, Tandon A.

J Neurol Surg Rep. 2015 Nov;76(2):e282-6. doi: 10.1055/s-0035-1566125. Epub 2015 Oct 29.


Connective tissue growth factor as a novel therapeutic target in high grade serous ovarian cancer.

Moran-Jones K, Gloss BS, Murali R, Chang DK, Colvin EK, Jones MD, Yuen S, Howell VM, Brown LM, Wong CW, Spong SM, Scarlett CJ, Hacker NF, Ghosh S, Mok SC, Birrer MJ, Samimi G.

Oncotarget. 2015 Dec 29;6(42):44551-62. doi: 10.18632/oncotarget.6082.


Morphological and Immunohistochemical Reevaluation of Tumors Initially Diagnosed as Ovarian Endometrioid Carcinoma With Emphasis on High-grade Tumors.

Lim D, Murali R, Murray MP, Veras E, Park KJ, Soslow RA.

Am J Surg Pathol. 2016 Mar;40(3):302-12. doi: 10.1097/PAS.0000000000000550.


Knowledge, attitude, and practice of needle stick and sharps injuries among dental professionals of Bangalore, India.

Pavithran VK, Murali R, Krishna M, Shamala A, Yalamalli M, Kumar AV.

J Int Soc Prev Community Dent. 2015 Sep-Oct;5(5):406-12. doi: 10.4103/2231-0762.165932.


Performance of Vitek MS in identifying nontuberculous mycobacteria from MGIT liquid medium and Lowenstein-Jensen solid medium.

Kehrmann J, Schoerding AK, Murali R, Wessel S, Koehling HL, Mosel F, Buer J.

Diagn Microbiol Infect Dis. 2016 Jan;84(1):43-47. doi: 10.1016/j.diagmicrobio.2015.10.007. Epub 2015 Oct 9.


The Potential Role of Solvation in Antibody Recognition of the Lewis Y Antigen.

Saha S, Murali R, Pashov A, Kieber-Emmons T.

Monoclon Antib Immunodiagn Immunother. 2015 Oct;34(5):295-302. doi: 10.1089/mab.2015.0037.

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