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Items: 1 to 50 of 273

1.

S-Ketamine Mediates Its Acute and Sustained Antidepressant-Like Activity through a 5-HT1B Receptor Dependent Mechanism in a Genetic Rat Model of Depression.

du Jardin KG, Liebenberg N, Cajina M, Müller HK, Elfving B, Sanchez C, Wegener G.

Front Pharmacol. 2018 Jan 15;8:978. doi: 10.3389/fphar.2017.00978. eCollection 2017.

2.

Cholesterol binding to a conserved site modulates conformation, pharmacology and transport kinetics of the human serotonin transporter.

Laursen L, Severinsen K, Kristensen KB, Periole X, Overby M, Müller HK, Schiøtt B, Sinning S.

J Biol Chem. 2018 Jan 19. pii: jbc.M117.809046. doi: 10.1074/jbc.M117.809046. [Epub ahead of print]

3.

β-catenin, Twist and Snail: Transcriptional regulation of EMT in smokers and COPD, and relation to airflow obstruction.

Mahmood MQ, Walters EH, Shukla SD, Weston S, Muller HK, Ward C, Sohal SS.

Sci Rep. 2017 Sep 7;7(1):10832. doi: 10.1038/s41598-017-11375-x.

4.

Lactation-Based Maternal Educational Immunity Crosses MHC Class I Barriers and Can Impart Th1 Immunity to Th2-Biased Recipients.

Ghosh MK, Muller HK, Walker AM.

J Immunol. 2017 Sep 1;199(5):1729-1736. doi: 10.4049/jimmunol.1601375. Epub 2017 Jul 26.

5.

Drugs with antidepressant properties affect tryptophan metabolites differently in rodent models with depression-like behavior.

Eskelund A, Li Y, Budac DP, Müller HK, Gulinello M, Sanchez C, Wegener G.

J Neurochem. 2017 Jul;142(1):118-131. doi: 10.1111/jnc.14043. Epub 2017 May 16.

PMID:
28407315
6.

Serotonin Transporter Associated Protein Complexes Are Enriched in Synaptic Vesicle Proteins and Proteins Involved in Energy Metabolism and Ion Homeostasis.

Haase J, Grudzinska-Goebel J, Müller HK, Münster-Wandowski A, Chow E, Wynne K, Farsi Z, Zander JF, Ahnert-Hilger G.

ACS Chem Neurosci. 2017 May 17;8(5):1101-1116. doi: 10.1021/acschemneuro.6b00437. Epub 2017 Apr 21.

PMID:
28362488
7.

Profiling cellular and inflammatory changes in the airway wall of mild to moderate COPD.

Eapen MS, McAlinden K, Tan D, Weston S, Ward C, Muller HK, Walters EH, Sohal SS.

Respirology. 2017 Aug;22(6):1125-1132. doi: 10.1111/resp.13021. Epub 2017 Mar 22.

PMID:
28326668
8.

Epithelial mesenchymal transition (EMT) and non-small cell lung cancer (NSCLC): a mutual association with airway disease.

Mahmood MQ, Ward C, Muller HK, Sohal SS, Walters EH.

Med Oncol. 2017 Mar;34(3):45. doi: 10.1007/s12032-017-0900-y. Epub 2017 Feb 14.

PMID:
28197929
9.

Melanocyte transformation requires complete loss of all pocket protein function via a mechanism that mitigates the need for MAPK pathway activation.

Tonks ID, Mukhopadhyay P, Schroder WA, Sorolla A, Mould AW, Handoko HY, Ferguson B, Muller HK, Keith P, Hayward NK, Walker GJ, Kay GF.

Oncogene. 2017 Jun 29;36(26):3789-3795. doi: 10.1038/onc.2016.511. Epub 2017 Feb 13.

PMID:
28192409
10.

The main rhinovirus respiratory tract adhesion site (ICAM-1) is upregulated in smokers and patients with chronic airflow limitation (CAL).

Shukla SD, Mahmood MQ, Weston S, Latham R, Muller HK, Sohal SS, Walters EH.

Respir Res. 2017 Jan 5;18(1):6. doi: 10.1186/s12931-016-0483-8.

11.

The expression of plasticity-related genes in an acute model of stress is modulated by chronic desipramine in a time-dependent manner within medial prefrontal cortex.

Nava N, Treccani G, Müller HK, Popoli M, Wegener G, Elfving B.

Eur Neuropsychopharmacol. 2017 Jan;27(1):19-28. doi: 10.1016/j.euroneuro.2016.11.010. Epub 2016 Nov 24.

PMID:
27890541
12.

Inhaled corticosteroid normalizes some but not all airway vascular remodeling in COPD.

Soltani A, Walters EH, Reid DW, Shukla SD, Nowrin K, Ward C, Muller HK, Sohal SS.

Int J Chron Obstruct Pulmon Dis. 2016 Sep 22;11:2359-2367. eCollection 2016.

13.

Transforming growth factor (TGF) β1 and Smad signalling pathways: A likely key to EMT-associated COPD pathogenesis.

Mahmood MQ, Reid D, Ward C, Muller HK, Knight DA, Sohal SS, Walters EH.

Respirology. 2017 Jan;22(1):133-140. doi: 10.1111/resp.12882. Epub 2016 Sep 11.

PMID:
27614607
14.

Gene expression related to serotonergic and glutamatergic neurotransmission is altered in the flinders sensitive line rat model of depression: Effect of ketamine.

Du Jardin KG, Müller HK, Sanchez C, Wegener G, Elfving B.

Synapse. 2017 Jan;71(1):37-45. doi: 10.1002/syn.21940. Epub 2016 Nov 11.

PMID:
27589698
15.

Maternal Milk T Cells Drive Development of Transgenerational Th1 Immunity in Offspring Thymus.

Ghosh MK, Nguyen V, Muller HK, Walker AM.

J Immunol. 2016 Sep 15;197(6):2290-6. doi: 10.4049/jimmunol.1502483. Epub 2016 Aug 5.

16.

Potential involvement of serotonergic signaling in ketamine's antidepressant actions: A critical review.

du Jardin KG, Müller HK, Elfving B, Dale E, Wegener G, Sanchez C.

Prog Neuropsychopharmacol Biol Psychiatry. 2016 Nov 3;71:27-38. doi: 10.1016/j.pnpbp.2016.05.007. Epub 2016 Jun 2. Review.

PMID:
27262695
17.

Differential expression of postsynaptic NMDA and AMPA receptor subunits in the hippocampus and prefrontal cortex of the flinders sensitive line rat model of depression.

Treccani G, Gaarn du Jardin K, Wegener G, Müller HK.

Synapse. 2016 Nov;70(11):471-4. doi: 10.1002/syn.21918. Epub 2016 Jun 21.

PMID:
27262028
18.

Differential interaction with the serotonin system by S-ketamine, vortioxetine, and fluoxetine in a genetic rat model of depression.

du Jardin KG, Liebenberg N, Müller HK, Elfving B, Sanchez C, Wegener G.

Psychopharmacology (Berl). 2016 Jul;233(14):2813-25. doi: 10.1007/s00213-016-4327-5. Epub 2016 May 28.

PMID:
27236785
19.

A single dose of vortioxetine, but not ketamine or fluoxetine, increases plasticity-related gene expression in the rat frontal cortex.

du Jardin KG, Müller HK, Sanchez C, Wegener G, Elfving B.

Eur J Pharmacol. 2016 Sep 5;786:29-35. doi: 10.1016/j.ejphar.2016.05.029. Epub 2016 May 25.

PMID:
27235984
20.

Protein biomarkers of susceptibility and resilience to stress in a rat model of depression.

Palmfeldt J, Henningsen K, Eriksen SA, Müller HK, Wiborg O.

Mol Cell Neurosci. 2016 Jul;74:87-95. doi: 10.1016/j.mcn.2016.04.001. Epub 2016 Apr 20.

PMID:
27105822
21.

Platelet-activating factor receptor (PAFr) is upregulated in small airways and alveoli of smokers and COPD patients.

Shukla SD, Muller HK, Latham R, Sohal SS, Walters EH.

Respirology. 2016 Apr;21(3):504-10. doi: 10.1111/resp.12709. Epub 2015 Dec 10.

22.

Murine melanomas accelerated by a single UVR exposure carry photoproduct footprints but lack UV signature C>T mutations in critical genes.

Mukhopadhyay P, Ferguson B, Muller HK, Handoko HY, Walker GJ.

Oncogene. 2016 Jun 23;35(25):3342-50. doi: 10.1038/onc.2015.386. Epub 2015 Oct 19.

PMID:
26477315
23.

Epithelial mesenchymal transition in smokers: large versus small airways and relation to airflow obstruction.

Mahmood MQ, Sohal SS, Shukla SD, Ward C, Hardikar A, Noor WD, Muller HK, Knight DA, Walters EH.

Int J Chron Obstruct Pulmon Dis. 2015 Aug 4;10:1515-24. doi: 10.2147/COPD.S81032. eCollection 2015.

24.

Lack of Evidence From a Transgenic Mouse Model that the Activation and Migration of Melanocytes to the Epidermis after Neonatal UVR Enhances Melanoma Development.

Handoko HY, Rodero MP, Muller HK, Khosrotehrani K, Walker GJ.

J Invest Dermatol. 2015 Nov;135(11):2897-2900. doi: 10.1038/jid.2015.203. Epub 2015 Jun 2. No abstract available.

25.

Chronic lipopolysaccharide infusion fails to induce depressive-like behaviour in adult male rats.

Fischer CW, Liebenberg N, Madsen AM, Müller HK, Lund S, Wegener G.

Acta Neuropsychiatr. 2015 Jun;27(3):189-94. doi: 10.1017/neu.2015.4. Epub 2015 Feb 20.

PMID:
25697068
26.

Chronic restraint stress increases the protein expression of VEGF and its receptor VEGFR-2 in the prefrontal cortex.

Elfving B, Jakobsen JL, Madsen JC, Wegener G, Müller HK.

Synapse. 2015 Apr;69(4):190-4. doi: 10.1002/syn.21808. Epub 2015 Feb 19.

PMID:
25655083
27.

Airway epithelial platelet-activating factor receptor expression is markedly upregulated in chronic obstructive pulmonary disease.

Shukla SD, Sohal SS, Mahmood MQ, Reid D, Muller HK, Walters EH.

Int J Chron Obstruct Pulmon Dis. 2014 Aug 13;9:853-61. doi: 10.2147/COPD.S67044. eCollection 2014.

28.

Melanoma susceptibility as a complex trait: genetic variation controls all stages of tumor progression.

Ferguson B, Ram R, Handoko HY, Mukhopadhyay P, Muller HK, Soyer HP, Morahan G, Walker GJ.

Oncogene. 2015 May 28;34(22):2879-86. doi: 10.1038/onc.2014.227. Epub 2014 Aug 4.

PMID:
25088201
29.

A randomized controlled trial of inhaled corticosteroids (ICS) on markers of epithelial-mesenchymal transition (EMT) in large airway samples in COPD: an exploratory proof of concept study.

Sohal SS, Soltani A, Reid D, Ward C, Wills KE, Muller HK, Walters EH.

Int J Chron Obstruct Pulmon Dis. 2014 May 27;9:533-42. doi: 10.2147/COPD.S63911. eCollection 2014.

30.

Differential regulation of the serotonin transporter by vesicle-associated membrane protein 2 in cells of neuronal versus non-neuronal origin.

Müller HK, Kragballe M, Fjorback AW, Wiborg O.

PLoS One. 2014 May 30;9(5):e97540. doi: 10.1371/journal.pone.0097540. eCollection 2014.

31.

Plasticity of melanoma in vivo: murine lesions resulting from Trp53, but not Cdk4 or Arf deregulation, display neural transdifferentiation.

Handoko HY, Boyle GM, Ferguson B, Muller HK, Soyer HP, Walker GJ.

Pigment Cell Melanoma Res. 2013 Sep;26(5):731-4. doi: 10.1111/pcmr.12124. Epub 2013 Jun 20.

PMID:
23724991
32.

Changes in airway histone deacetylase2 in smokers and COPD with inhaled corticosteroids: a randomized controlled trial.

Sohal SS, Reid D, Soltani A, Weston S, Muller HK, Wood-Baker R, Walters EH.

PLoS One. 2013 May 22;8(5):e64833. doi: 10.1371/journal.pone.0064833. Print 2013.

33.

A gene-environment study of cytoglobin in the human and rat hippocampus.

Hundahl CA, Elfving B, Müller HK, Hay-Schmidt A, Wegener G.

PLoS One. 2013 May 16;8(5):e63288. doi: 10.1371/journal.pone.0063288. Print 2013.

34.

Ketamine regulates the presynaptic release machinery in the hippocampus.

Müller HK, Wegener G, Liebenberg N, Zarate CA Jr, Popoli M, Elfving B.

J Psychiatr Res. 2013 Jul;47(7):892-9. doi: 10.1016/j.jpsychires.2013.03.008. Epub 2013 Mar 30.

35.

Ultraviolet radiation effects on the proteome of skin cells.

Muller HK, Woods GM.

Adv Exp Med Biol. 2013;990:111-9. doi: 10.1007/978-94-007-5896-4_8. Review.

PMID:
23378007
36.

UVB-induced melanocyte proliferation in neonatal mice driven by CCR2-independent recruitment of Ly6c(low)MHCII(hi) macrophages.

Handoko HY, Rodero MP, Boyle GM, Ferguson B, Engwerda C, Hill G, Muller HK, Khosrotehrani K, Walker GJ.

J Invest Dermatol. 2013 Jul;133(7):1803-12. doi: 10.1038/jid.2013.9. Epub 2013 Jan 15.

37.

Dietary vitamin D alters the response of the skin to UVB-irradiation depending on the genetic background of the mice.

Malley RC, Muller HK, Norval M, Woods GM.

Photochem Photobiol Sci. 2013 Mar;12(3):536-45. doi: 10.1039/c2pp25211b.

PMID:
23258584
38.

Reticular Basement Membrane Vessels Are Increased in COPD Bronchial Mucosa by Both Factor VIII and Collagen IV Immunostaining and Are Hyperpermeable.

Soltani A, Wood-Baker R, Sohal SS, Muller HK, Reid D, Walters EH.

J Allergy (Cairo). 2012;2012:958383. doi: 10.1155/2012/958383. Epub 2012 Feb 27.

39.

The Schizophrenia and Bipolar Disorder associated BRD1 gene is regulated upon chronic restraint stress.

Christensen JH, Elfving B, Müller HK, Fryland T, Nyegaard M, Corydon TJ, Nielsen AL, Mors O, Wegener G, Børglum AD.

Eur Neuropsychopharmacol. 2012 Sep;22(9):651-6. doi: 10.1016/j.euroneuro.2012.01.005. Epub 2012 Feb 17.

PMID:
22341945
40.

Distinctive characteristics of bronchial reticular basement membrane and vessel remodelling in chronic obstructive pulmonary disease (COPD) and in asthma: they are not the same disease.

Soltani A, Muller HK, Sohal SS, Reid DW, Weston S, Wood-Baker R, Walters EH.

Histopathology. 2012 May;60(6):964-70. doi: 10.1111/j.1365-2559.2011.04147.x. Epub 2012 Feb 9.

41.

Wistar rats subjected to chronic restraint stress display increased hippocampal spine density paralleled by increased expression levels of synaptic scaffolding proteins.

Orlowski D, Elfving B, Müller HK, Wegener G, Bjarkam CR.

Stress. 2012 Sep;15(5):514-23. doi: 10.3109/10253890.2011.643516. Epub 2012 Jan 10.

PMID:
22128856
42.

Evaluation of epithelial mesenchymal transition in patients with chronic obstructive pulmonary disease.

Sohal SS, Reid D, Soltani A, Ward C, Weston S, Muller HK, Wood-Baker R, Walters EH.

Respir Res. 2011 Oct 5;12:130. doi: 10.1186/1465-9921-12-130.

43.

Chronic restraint stress affects serotonin transporter uptake kinetics but not binding sites in the rat hippocampus.

Müller HK, Wegener G, Elfving B.

Synapse. 2012 Mar;66(3):270-2. doi: 10.1002/syn.20986. Epub 2011 Nov 28. No abstract available.

PMID:
21954049
44.

An inhibitor of cAMP-dependent protein kinase induces behavioural and neurological antidepressant-like effects in rats.

Liebenberg N, Müller HK, Fischer CW, Harvey BH, Brink CB, Elfving B, Wegener G.

Neurosci Lett. 2011 Jul 8;498(2):158-61. doi: 10.1016/j.neulet.2011.05.004. Epub 2011 May 8.

PMID:
21596096
45.

Differential expression of synaptic proteins after chronic restraint stress in rat prefrontal cortex and hippocampus.

Müller HK, Wegener G, Popoli M, Elfving B.

Brain Res. 2011 Apr 18;1385:26-37. doi: 10.1016/j.brainres.2011.02.048. Epub 2011 Feb 24.

PMID:
21354112
46.

Superficial spreading-like melanoma in Arf(-/-)::Tyr-Nras(Q61K)::K14-Kitl mice: keratinocyte Kit ligand expression sufficient to "translocate" melanomas from dermis to epidermis.

Walker GJ, Soyer HP, Handoko HY, Ferguson B, Kunisada T, Khosrotehrani K, Box NF, Muller HK.

J Invest Dermatol. 2011 Jun;131(6):1384-7. doi: 10.1038/jid.2011.21. Epub 2011 Feb 10. No abstract available.

47.

Modulation of the dopamine transporter by interaction with Secretory Carrier Membrane Protein 2.

Fjorback AW, Müller HK, Haase J, Raarup MK, Wiborg O.

Biochem Biophys Res Commun. 2011 Mar 11;406(2):165-70. doi: 10.1016/j.bbrc.2011.01.069. Epub 2011 Feb 3.

PMID:
21295544
48.

Neonatal exposure to UVR alters skin immune system development, and suppresses immunity in adulthood.

McGee HM, Malley RC, Muller HK, Woods GM.

Immunol Cell Biol. 2011 Oct;89(7):767-76. doi: 10.1038/icb.2010.170. Epub 2011 Jan 18.

PMID:
21243005
49.

Basement membrane and vascular remodelling in smokers and chronic obstructive pulmonary disease: a cross-sectional study.

Soltani A, Reid DW, Sohal SS, Wood-Baker R, Weston S, Muller HK, Walters EH.

Respir Res. 2010 Jul 30;11:105. doi: 10.1186/1465-9921-11-105.

50.

Reticular basement membrane fragmentation and potential epithelial mesenchymal transition is exaggerated in the airways of smokers with chronic obstructive pulmonary disease.

Sohal SS, Reid D, Soltani A, Ward C, Weston S, Muller HK, Wood-Baker R, Walters EH.

Respirology. 2010 Aug;15(6):930-8. doi: 10.1111/j.1440-1843.2010.01808.x. Epub 2010 Jul 12.

PMID:
20630030

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