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Items: 24


The antiprotease SPINK7 serves as an inhibitory checkpoint for esophageal epithelial inflammatory responses.

Azouz NP, Ynga-Durand MA, Caldwell JM, Jain A, Rochman M, Fischesser DM, Ray LM, Bedard MC, Mingler MK, Forney C, Eilerman M, Kuhl JT, He H, Biagini Myers JM, Mukkada VA, Putnam PE, Khurana Hershey GK, Kottyan LC, Wen T, Martin LJ, Rothenberg ME.

Sci Transl Med. 2018 Jun 6;10(444). pii: eaap9736. doi: 10.1126/scitranslmed.aap9736.


Alignment of Parent- and Child-Reported Outcomes and Histology in Eosinophilic Esophagitis Across Multiple CEGIR Sites.

Aceves SS, King E, Collins MH, Yang GY, Capocelli KE, Abonia JP, Atkins D, Bonis PA, Carpenter CL, Dellon ES, Eby MD, Falk GW, Gonsalves N, Gupta SK, Hirano I, Kocher K, Krischer JP, Leung J, Lipscomb J, Menard-Katcher P, Mukkada VA, Pan Z, Spergel JM, Sun Q, Wershil BK, Rothenberg ME, Furuta GT; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR).

J Allergy Clin Immunol. 2018 May 28. pii: S0091-6749(18)30774-7. doi: 10.1016/j.jaci.2018.05.014. [Epub ahead of print]


Esophageal IgG4 Levels Correlate with Histopathologic and Transcriptomic Features in Eosinophilic Esophagitis.

Rosenberg CE, Mingler MK, Caldwell JM, Collins MH, Fulkerson PC, Morris DW, Mukkada VA, Putnam PE, Shoda T, Wen T, Rothenberg ME.

Allergy. 2018 May 23. doi: 10.1111/all.13486. [Epub ahead of print]


Eosinophilic oesophagitis endotype classification by molecular, clinical, and histopathological analyses: a cross-sectional study.

Shoda T, Wen T, Aceves SS, Abonia JP, Atkins D, Bonis PA, Caldwell JM, Capocelli KE, Carpenter CL, Collins MH, Dellon ES, Eby MD, Gonsalves N, Gupta SK, Falk GW, Hirano I, Menard-Katcher P, Kuhl JT, Krischer JP, Leung J, Mukkada VA, Spergel JM, Trimarchi MP, Yang GY, Zimmermann N, Furuta GT, Rothenberg ME; Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR).

Lancet Gastroenterol Hepatol. 2018 Jul;3(7):477-488. doi: 10.1016/S2468-1253(18)30096-7. Epub 2018 May 3.


Solute carrier family 9, subfamily A, member 3 (SLC9A3)/sodium-hydrogen exchanger member 3 (NHE3) dysregulation and dilated intercellular spaces in patients with eosinophilic esophagitis.

Zeng C, Vanoni S, Wu D, Caldwell JM, Wheeler JC, Arora K, Noah TK, Waggoner L, Besse JA, Yamani AN, Uddin J, Rochman M, Wen T, Chehade M, Collins MH, Mukkada VA, Putnam PE, Naren AP, Rothenberg ME, Hogan SP.

J Allergy Clin Immunol. 2018 May 4. pii: S0091-6749(18)30633-X. doi: 10.1016/j.jaci.2018.03.017. [Epub ahead of print]


Eosinophilic Esophagitis: an Important Comorbid Condition of Asthma?

Durrani SR, Mukkada VA, Guilbert TW.

Clin Rev Allergy Immunol. 2018 Feb 18. doi: 10.1007/s12016-018-8670-7. [Epub ahead of print] Review.


Creating a multi-center rare disease consortium - the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR).

Cheng K, Gupta SK, Kantor S, Kuhl JT, Aceves SS, Bonis PA, Capocelli KE, Carpenter C, Chehade M, Collins MH, Dellon ES, Falk GW, Gopal-Srivastava R, Gonsalves N, Hirano I, King EC, Leung J, Krischer JP, Mukkada VA, Schoepfer A, Spergel JM, Straumann A, Yang GY, Furuta GT, Rothenberg ME.

Transl Sci Rare Dis. 2017 Dec 18;2(3-4):141-155. doi: 10.3233/TRD-170016.


Pediatric Eosinophilic Esophagitis Endotypes: Are We Closer to Predicting Treatment Response?

Ferguson AE, Mukkada VA, Fulkerson PC.

Clin Rev Allergy Immunol. 2017 Dec 21. doi: 10.1007/s12016-017-8658-8. [Epub ahead of print] Review.


Eosinophil progenitor levels are increased in patients with active pediatric eosinophilic esophagitis.

Morris DW, Stucke EM, Martin LJ, Abonia JP, Mukkada VA, Putnam PE, Rothenberg ME, Fulkerson PC.

J Allergy Clin Immunol. 2016 Sep;138(3):915-918.e5. doi: 10.1016/j.jaci.2016.03.027. Epub 2016 May 16. No abstract available.


A retrospective review of cyproheptadine for feeding intolerance in children less than three years of age: effects and side effects.

Merhar SL, Pentiuk SP, Mukkada VA, Meinzen-Derr J, Kaul A, Butler DR.

Acta Paediatr. 2016 Aug;105(8):967-70. doi: 10.1111/apa.13477. Epub 2016 Jun 10.


Substantial Variability in Biopsy Practice Patterns Among Gastroenterologists for Suspected Eosinophilic Gastrointestinal Disorders.

Dellon ES, Collins MH, Bonis PA, Leung J, Capocelli KE, Dohil R, Falk GW, Furuta GT, Menard-Katcher C, Gupta SK, Hirano I, Hiremath GS, Kagalwalla AF, Wershil BK, Liacouras CA, Muir AB, Mukkada VA, Putnam PE, Schoepfer AM, Straumann A, Wo JM, Yang GY, Rothenberg ME, Gonsalves N.

Clin Gastroenterol Hepatol. 2016 Dec;14(12):1842-1844. doi: 10.1016/j.cgh.2016.04.025. Epub 2016 Apr 22. No abstract available.



Golekoh MC, Mukkada VA, Putnam PE, Backeljauw PF.

J Pediatr. 2016 Jul;174:281-2. doi: 10.1016/j.jpeds.2016.02.063. Epub 2016 Mar 19. No abstract available.


Newly developed and validated eosinophilic esophagitis histology scoring system and evidence that it outperforms peak eosinophil count for disease diagnosis and monitoring.

Collins MH, Martin LJ, Alexander ES, Boyd JT, Sheridan R, He H, Pentiuk S, Putnam PE, Abonia JP, Mukkada VA, Franciosi JP, Rothenberg ME.

Dis Esophagus. 2017 Feb 1;30(3):1-8. doi: 10.1111/dote.12470.


Should wheat, barley, rye, and/or gluten be avoided in a 6-food elimination diet?

Kliewer KL, Venter C, Cassin AM, Abonia JP, Aceves SS, Bonis PA, Dellon ES, Falk GW, Furuta GT, Gonsalves N, Gupta SK, Hirano I, Kagalwalla A, Leung J, Mukkada VA, Spergel JM, Rothenberg ME.

J Allergy Clin Immunol. 2016 Apr;137(4):1011-1014. doi: 10.1016/j.jaci.2015.10.040. Epub 2015 Dec 24.


Adrenal Insufficiency after Chronic Swallowed Glucocorticoid Therapy for Eosinophilic Esophagitis.

Golekoh MC, Hornung LN, Mukkada VA, Khoury JC, Putnam PE, Backeljauw PF.

J Pediatr. 2016 Mar;170:240-5. doi: 10.1016/j.jpeds.2015.11.026. Epub 2015 Dec 11.


Twin and family studies reveal strong environmental and weaker genetic cues explaining heritability of eosinophilic esophagitis.

Alexander ES, Martin LJ, Collins MH, Kottyan LC, Sucharew H, He H, Mukkada VA, Succop PA, Abonia JP, Foote H, Eby MD, Grotjan TM, Greenler AJ, Dellon ES, Demain JG, Furuta GT, Gurian LE, Harley JB, Hopp RJ, Kagalwalla A, Kaul A, Nadeau KC, Noel RJ, Putnam PE, von Tiehl KF, Rothenberg ME.

J Allergy Clin Immunol. 2014 Nov;134(5):1084-1092.e1. doi: 10.1016/j.jaci.2014.07.021. Epub 2014 Sep 22.


Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease.

Kottyan LC, Davis BP, Sherrill JD, Liu K, Rochman M, Kaufman K, Weirauch MT, Vaughn S, Lazaro S, Rupert AM, Kohram M, Stucke EM, Kemme KA, Magnusen A, He H, Dexheimer P, Chehade M, Wood RA, Pesek RD, Vickery BP, Fleischer DM, Lindbad R, Sampson HA, Mukkada VA, Putnam PE, Abonia JP, Martin LJ, Harley JB, Rothenberg ME.

Nat Genet. 2014 Aug;46(8):895-900. doi: 10.1038/ng.3033. Epub 2014 Jul 13.


Analysis and expansion of the eosinophilic esophagitis transcriptome by RNA sequencing.

Sherrill JD, Kiran KC, Blanchard C, Stucke EM, Kemme KA, Collins MH, Abonia JP, Putnam PE, Mukkada VA, Kaul A, Kocoshis SA, Kushner JP, Plassard AJ, Karns RA, Dexheimer PJ, Aronow BJ, Rothenberg ME.

Genes Immun. 2014 Sep;15(6):361-9. doi: 10.1038/gene.2014.27. Epub 2014 Jun 12.


Management of refractory eosinophilic esophagitis.

Mukkada VA, Furuta GT.

Dig Dis. 2014;32(1-2):134-8. doi: 10.1159/000357296. Epub 2014 Feb 28.


Expression microarray analysis identifies novel epithelial-derived protein markers in eosinophilic esophagitis.

Matoso A, Mukkada VA, Lu S, Monahan R, Cleveland K, Noble L, Mangray S, Resnick MB.

Mod Pathol. 2013 May;26(5):665-76. doi: 10.1038/modpathol.2013.41. Epub 2013 Mar 15.


MicroRNA profiling in mucosal biopsies of eosinophilic esophagitis patients pre and post treatment with steroids and relationship with mRNA targets.

Lu S, Mukkada VA, Mangray S, Cleveland K, Shillingford N, Schorl C, Brodsky AS, Resnick MB.

PLoS One. 2012;7(7):e40676. doi: 10.1371/journal.pone.0040676. Epub 2012 Jul 16.


Feeding dysfunction in children with eosinophilic gastrointestinal diseases.

Mukkada VA, Haas A, Maune NC, Capocelli KE, Henry M, Gilman N, Petersburg S, Moore W, Lovell MA, Fleischer DM, Furuta GT, Atkins D.

Pediatrics. 2010 Sep;126(3):e672-7. doi: 10.1542/peds.2009-2227. Epub 2010 Aug 9.


Idiopathic eosinophilic disorders of the gastrointestinal tract in children.

Mukkada VA, Furuta GT.

Best Pract Res Clin Gastroenterol. 2008;22(3):497-509. doi: 10.1016/j.bpg.2007.09.002. Review.


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