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Items: 1 to 50 of 151

1.

Sensitive monitoring of acute promyelocytic leukemia by PML-RARA DNA Q-PCR.

Kommers IO, Bartley PA, Budgen B, Latham S, Beligaswatte A, Supple SG, Catalano A, Iland HJ, Morley AA, Ross DM.

Leuk Lymphoma. 2017 Jul;58(7):1767-1769. doi: 10.1080/10428194.2016.1262033. Epub 2016 Nov 30. No abstract available.

PMID:
27899039
2.

Reporting results for deep molecular responses in chronic myeloid leukemia.

Morley AA.

Leukemia. 2016 Jul;30(7):1630-1. doi: 10.1038/leu.2016.94. Epub 2016 May 17. No abstract available.

PMID:
27183878
3.

BCR-ABL1 expression, RT-qPCR and treatment decisions in chronic myeloid leukaemia.

Latham S, Bartley PA, Budgen B, Ross DM, Hughes E, Branford S, White D, Hughes TP, Morley AA.

J Clin Pathol. 2016 Sep;69(9):817-21. doi: 10.1136/jclinpath-2015-203538. Epub 2016 Feb 2.

PMID:
26837312
4.

A DNA real-time quantitative PCR method suitable for routine monitoring of low levels of minimal residual disease in chronic myeloid leukemia.

Bartley PA, Latham S, Budgen B, Ross DM, Hughes E, Branford S, White D, Hughes TP, Morley AA.

J Mol Diagn. 2015 Mar;17(2):185-92. doi: 10.1016/j.jmoldx.2014.10.002. Epub 2014 Dec 29.

PMID:
25554588
5.

Digital PCR: A brief history.

Morley AA.

Biomol Detect Quantif. 2014 Aug 15;1(1):1-2. eCollection 2014 Sep. Review.

6.

Distribution of genomic breakpoints in chronic myeloid leukemia: analysis of 308 patients.

Ross DM, O'Hely M, Bartley PA, Dang P, Score J, Goyne JM, Sobrinho-Simoes M, Cross NC, Melo JV, Speed TP, Hughes TP, Morley AA.

Leukemia. 2013 Oct;27(10):2105-7. doi: 10.1038/leu.2013.116. Epub 2013 Apr 16. No abstract available.

PMID:
23588714
7.

Quantification of RNA integrity and its use for measurement of transcript number.

Brisco MJ, Morley AA.

Nucleic Acids Res. 2012 Oct;40(18):e144. doi: 10.1093/nar/gks588. Epub 2012 Jun 25.

8.

Durable complete molecular remission of chronic myeloid leukemia following dasatinib cessation, despite adverse disease features.

Ross DM, Bartley PA, Goyne J, Morley AA, Seymour JF, Grigg AP.

Haematologica. 2011 Nov;96(11):1720-2. doi: 10.3324/haematol.2011.048165. Epub 2011 Aug 9.

9.

Incorporation of measurement of DNA integrity into qPCR assays.

Brisco MJ, Latham S, Bartley PA, Morley AA.

Biotechniques. 2010 Dec;49(6):893-7. doi: 10.2144/000113567.

10.

Antisense PCR: A simple and robust method for performing nested single-tube PCR.

Brisco MJ, Bartley PA, Morley AA.

Anal Biochem. 2011 Feb 15;409(2):176-82. doi: 10.1016/j.ab.2010.10.030. Epub 2010 Oct 30.

PMID:
21040697
11.

Sensitive detection and quantification of minimal residual disease in chronic myeloid leukaemia using nested quantitative PCR for BCR-ABL DNA.

Bartley PA, Ross DM, Latham S, Martin-Harris MH, Budgen B, Wilczek V, Branford S, Hughes TP, Morley AA.

Int J Lab Hematol. 2010 Dec;32(6 Pt 1):e222-8. doi: 10.1111/j.1751-553X.2010.01236.x.

PMID:
20491997
12.

Gene walking using sequential hybrid primer polymerase chain reaction.

Martin-Harris MH, Bartley PA, Morley AA.

Anal Biochem. 2010 Apr 15;399(2):308-10. doi: 10.1016/j.ab.2010.01.005. Epub 2010 Jan 13.

PMID:
20074545
13.

Rapid isolation of translocation breakpoints in chronic myeloid and acute promyelocytic leukaemia.

Bartley PA, Martin-Harris MH, Budgen BJ, Ross DM, Morley AA.

Br J Haematol. 2010 Apr;149(2):231-6. doi: 10.1111/j.1365-2141.2009.08071.x. Epub 2010 Jan 11.

PMID:
20067557
14.

Determining the repertoire of IGH gene rearrangements to develop molecular markers for minimal residual disease in B-lineage acute lymphoblastic leukemia.

Brisco MJ, Latham S, Sutton R, Hughes E, Wilczek V, van Zanten K, Budgen B, Bahar AY, Malec M, Sykes PJ, Kuss BJ, Waters K, Venn NC, Giles JE, Haber M, Norris MD, Marshall GM, Morley AA.

J Mol Diagn. 2009 May;11(3):194-200. doi: 10.2353/jmoldx.2009.080047. Epub 2009 Mar 26.

15.

Sensitive and specific measurement of minimal residual disease in acute lymphoblastic leukemia.

Morley AA, Latham S, Brisco MJ, Sykes PJ, Sutton R, Hughes E, Wilczek V, Budgen B, van Zanten K, Kuss BJ, Venn NC, Norris MD, Crock C, Storey C, Revesz T, Waters K.

J Mol Diagn. 2009 May;11(3):201-10. doi: 10.2353/jmoldx.2009.080048. Epub 2009 Mar 26.

16.

In vivo mutagenic effect of very low dose radiation.

Sykes PJ, Day TK, Swinburne SJ, Lane JM, Morley AA, Hooker AM, Bhat M.

Dose Response. 2006 Aug 19;4(4):309-16. doi: 10.2203/dose-response.06-004.Sykes.

17.

The PKZ1 recombination mutation assay: a sensitive assay for low dose studies.

Sykes PJ, Morley AA, Hooker AM.

Dose Response. 2006 Aug 19;4(2):91-105. doi: 10.2203/dose-response.05-035.Sykes.

18.
19.

The linear no-threshold model does not hold for low-dose ionizing radiation.

Hooker AM, Bhat M, Day TK, Lane JM, Swinburne SJ, Morley AA, Sykes PJ.

Radiat Res. 2004 Oct;162(4):447-52.

PMID:
15447037
20.

Cancer-associated genes can affect somatic intrachromosomal recombination early in carcinogenesis.

Hooker AM, Morley AA, Tilley WD, Sykes PJ.

Mutat Res. 2004 Jun 4;550(1-2):1-10.

PMID:
15135636
21.

Mitochondrial mutations in acute leukaemia.

Grist SA, Lu XJ, Morley AA.

Leukemia. 2004 Jul;18(7):1313-6. No abstract available.

PMID:
15129223
22.
23.

Evidence for whole chromosome 6 loss and duplication of the remaining chromosome in acute lymphoblastic leukemia.

McEvoy CR, Morley AA, Firgaira FA.

Genes Chromosomes Cancer. 2003 Jul;37(3):321-5.

PMID:
12759931
24.

Mitotic recombination is an important mutational event following oxidative damage.

Turner DR, Dreimanis M, Holt D, Firgaira FA, Morley AA.

Mutat Res. 2003 Jan 28;522(1-2):21-6. Review.

PMID:
12517408
25.

Frequency and genetic basis of MHC, beta-2-microglobulin and MEMO-1 loss of heterozygosity in sporadic breast cancer.

McEvoy CR, Seshadri R, Morley AA, Firgaira FA.

Tissue Antigens. 2002 Sep;60(3):235-43.

PMID:
12445306
26.

Dose-dependent increase or decrease of somatic intrachromosomal recombination produced by etoposide.

Hooker AM, Horne R, Morley AA, Sykes PJ.

Mutat Res. 2002 Mar 20;500(1-2):117-24. Erratum in: Mutat Res 2002 Aug 29;505(1-2):95. Home Rachael [corrected to Horne Rachel].

PMID:
11890941
27.

Lack of an effect of vitamin E on lifespan of mice.

Morley AA, Trainor KJ.

Biogerontology. 2001;2(2):109-12.

PMID:
11708376
28.

Molecular relapse can be detected in blood in a sensitive and timely fashion in B-lineage acute lymphoblastic leukemia.

Brisco MJ, Sykes PJ, Hughes E, Story CJ, Rice MS, Schwarer AP, Morley AA.

Leukemia. 2001 Nov;15(11):1801-2. No abstract available.

PMID:
11681428
29.

Effect of exposure to 900 MHz radiofrequency radiation on intrachromosomal recombination in pKZ1 mice.

Sykes PJ, McCallum BD, Bangay MJ, Hooker AM, Morley AA.

Radiat Res. 2001 Nov;156(5 Pt 1):495-502.

PMID:
11604062
30.

Purging of myeloma cells using all-trans retinoic acid in a mouse model.

Henry JM, Morley AA, Sykes PJ.

Exp Hematol. 2001 Mar;29(3):315-21.

PMID:
11274759
31.

Comparison of methods for assessment of minimal residual disease in childhood B-lineage acute lymphoblastic leukemia.

Brisco MJ, Sykes PJ, Hughes E, Neoh SH, Snell LE, Dolman G, Peng LM, Toogood IR, Cheney K, Rice MS, Story CJ, Morley AA.

Leukemia. 2001 Mar;15(3):385-90.

PMID:
11237061
32.

Early resistance to therapy during induction in childhood acute lymphoblastic leukemia.

Brisco MJ, Sykes PJ, Dolman G, Hughes E, Neoh SH, Peng L, Snell LE, Toogood IR, Rice MS, Morley AA.

Cancer Res. 2000 Sep 15;60(18):5092-6.

33.

The effect of cycle number and target size on polymerase chain reaction amplification of polymorphic repetitive sequences.

Toouli CD, Turner DR, Grist SA, Morley AA.

Anal Biochem. 2000 May 1;280(2):324-6. No abstract available.

PMID:
10790319
34.
35.

The contribution of exogenous and endogenous mutagens to in vivo mutations.

Morley AA, Turner DR.

Mutat Res. 1999 Jul 16;428(1-2):11-5. Review.

PMID:
10517973
36.

Inversion due to intrachromosomal recombination produced by carcinogens in a transgenic mouse model.

Sykes PJ, Hooker AM, Morley AA.

Mutat Res. 1999 Jun 1;427(1):1-9.

PMID:
10354496
37.

Minimal residual disease in childhood acute lymphoblastic leukaemia quantified by aspirate and trephine: is the disease multifocal?

Sykes PJ, Brisco MJ, Hughes E, Snell LE, Dolman G, Neoh SH, Peng LM, Toogood I, Venables WN, Morley AA.

Br J Haematol. 1998 Oct;103(1):60-5.

PMID:
9792290
38.

A method for assessing strand breaks in DNA.

Peng L, Brisco MJ, Morley AA.

Anal Biochem. 1998 Aug 15;262(1):9-16.

PMID:
9735142
39.

Accelerated accumulation of somatic mutations in the senescence-accelerated mouse.

Odagiri Y, Uchida H, Hosokawa M, Takemoto K, Morley AA, Takeda T.

Nat Genet. 1998 Jun;19(2):116-7. No abstract available.

PMID:
9620763
40.

Induction of somatic intrachromosomal recombination inversion events by cyclophosphamide in a transgenic mouse model.

Sykes PJ, Hooker AM, Harrington CS, Jacobs AK, Kingsbury L, Morley AA.

Mutat Res. 1998 Feb 2;397(2):209-19.

PMID:
9541645
41.

Monitoring minimal residual disease in peripheral blood in B-lineage acute lymphoblastic leukaemia.

Brisco MJ, Sykes PJ, Hughes E, Dolman G, Neoh SH, Peng LM, Toogood I, Morley AA.

Br J Haematol. 1997 Nov;99(2):314-9.

PMID:
9375747
42.

Leukaemia presenting as marrow hypoplasia: molecular detection of the leukaemic clone at the time of initial presentation.

Morley AA, Brisco MJ, Rice M, Snell L, Peng LM, Hughes E, Neoh SH, Sykes PJ.

Br J Haematol. 1997 Sep;98(4):940-4.

PMID:
9326193
43.

Effect of the Philadelphia chromosome on minimal residual disease in acute lymphoblastic leukemia.

Brisco MJ, Sykes PJ, Dolman G, Neoh SH, Hughes E, Peng LM, Tauro G, Ekert H, Toogood I, Bradstock K, Morley AA.

Leukemia. 1997 Sep;11(9):1497-500.

PMID:
9305604
44.

The use of monoclonal gene rearrangement for detection of minimal residual disease in acute lymphoblastic leukemia of childhood.

Sykes PJ, Snell LE, Brisco MJ, Neoh SH, Hughes E, Dolman G, Peng LM, Bennett A, Toogood I, Morley AA.

Leukemia. 1997 Jan;11(1):153-8.

PMID:
9001432
45.
46.

Relationship between minimal residual disease and outcome in adult acute lymphoblastic leukemia.

Brisco J, Hughes E, Neoh SH, Sykes PJ, Bradstock K, Enno A, Szer J, McCaul K, Morley AA.

Blood. 1996 Jun 15;87(12):5251-6.

47.

Comparison of myeloma cell contamination of bone marrow and peripheral blood stem cell harvests.

Henry JM, Sykes PJ, Brisco MJ, To LB, Juttner CA, Morley AA.

Br J Haematol. 1996 Mar;92(3):614-9.

PMID:
8616025
48.

Characterization of clonal immunoglobulin heavy chain and I cell receptor gamma gene rearrangements during progression of childhood acute lymphoblastic leukemia.

Marshall GM, Kwan E, Haber M, Brisco MJ, Sykes PJ, Morley AA, Toogood I, Waters K, Tauro G, Ekert H, et al.

Leukemia. 1995 Nov;9(11):1847-50.

PMID:
7475273
49.

The somatic mutation theory of ageing.

Morley AA.

Mutat Res. 1995 Oct;338(1-6):19-23. Review. No abstract available.

PMID:
7565875
50.

Treatment of acute myelogenous leukemia.

Morley AA.

N Engl J Med. 1995 Jun 22;332(25):1717; author reply 1718-9. No abstract available.

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