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Items: 1 to 50 of 644

1.

PHARMACOLOGICAL CHARACTERIZATION OF IW-1973, A NOVEL SOLUBLE GUANYLATE CYCLASE STIMULATOR WITH EXTENSIVE TISSUE DISTRIBUTION, ANTI-HYPERTENSIVE, ANTI-INFLAMMATORY, AND ANTI-FIBROTIC EFFECTS IN PRECLINICAL MODELS OF DISEASE.

Tobin JV, Zimmer DP, Shea C, Germano P, Bernier SG, Liu G, Long K, Miyashiro J, Ranganath S, Jacobson S, Tang K, Im GJ, Sheppeck J, Moore JD, Sykes K, Wakefield J, Sarno R, Banijamali AR, Profy AT, Milne GT, Currie MG, Masferrer JL.

J Pharmacol Exp Ther. 2018 Apr 11. pii: jpet.117.247429. doi: 10.1124/jpet.117.247429. [Epub ahead of print]

2.

Monomorphic pathogens: The case of Candidatus Xenohaliotis californiensis from abalone in California, USA and Baja California, Mexico.

Cicala F, Moore JD, Cáceres-Martínez J, Del Río-Portilla MA, Hernández-Rodríguez M, Vásquez-Yeomans R, Rocha-Olivares A.

J Invertebr Pathol. 2018 Mar 23;154:19-23. doi: 10.1016/j.jip.2018.03.012. [Epub ahead of print]

PMID:
29577877
3.

Transient rheology of the Sumatran mantle wedge revealed by a decade of great earthquakes.

Qiu Q, Moore JDP, Barbot S, Feng L, Hill EM.

Nat Commun. 2018 Mar 8;9(1):995. doi: 10.1038/s41467-018-03298-6.

4.

Differential expression of Lp-PLA2 in obesity and type 2 diabetes and the influence of lipids.

Jackisch L, Kumsaiyai W, Moore JD, Al-Daghri N, Kyrou I, Barber TM, Randeva H, Kumar S, Tripathi G, McTernan PG.

Diabetologia. 2018 May;61(5):1155-1166. doi: 10.1007/s00125-018-4558-6. Epub 2018 Feb 9.

PMID:
29427237
5.

The divergent fates of primitive hydrospheric water on Earth and Mars.

Wade J, Dyck B, Palin RM, Moore JDP, Smye AJ.

Nature. 2017 Dec 20;552(7685):391-394. doi: 10.1038/nature25031.

PMID:
29293210
6.

Dual direction CRISPR transcriptional regulation screening uncovers gene networks driving drug resistance.

le Sage C, Lawo S, Panicker P, Scales TME, Rahman SA, Little AS, McCarthy NJ, Moore JD, Cross BCS.

Sci Rep. 2017 Dec 18;7(1):17693. doi: 10.1038/s41598-017-18172-6.

7.

Implementation of a longitudinal early immersion student pharmacist health system internship program.

Amerine LB, Valgus JM, Moore JD, Arnall JR, Savage SW.

Curr Pharm Teach Learn. 2017 May;9(3):421-426. doi: 10.1016/j.cptl.2017.01.011. Epub 2017 Apr 12.

PMID:
29233280
8.

Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1).

Williamson DS, Smith GP, Acheson-Dossang P, Bedford ST, Chell V, Chen IJ, Daechsel JCA, Daniels Z, David L, Dokurno P, Hentzer M, Herzig MC, Hubbard RE, Moore JD, Murray JB, Newland S, Ray SC, Shaw T, Surgenor AE, Terry L, Thirstrup K, Wang Y, Christensen KV.

J Med Chem. 2017 Nov 9;60(21):8945-8962. doi: 10.1021/acs.jmedchem.7b01186. Epub 2017 Oct 27.

PMID:
29023112
9.

Changes in Gene Expression in Space and Time Orchestrate Environmentally Mediated Shaping of Root Architecture.

Walker L, Boddington C, Jenkins D, Wang Y, Grønlund JT, Hulsmans J, Kumar S, Patel D, Moore JD, Carter A, Samavedam S, Bonomo G, Hersh DS, Coruzzi GM, Burroughs NJ, Gifford ML.

Plant Cell. 2017 Oct;29(10):2393-2412. doi: 10.1105/tpc.16.00961. Epub 2017 Sep 11.

10.

The transcription factor Maf-S regulates metabolic resistance to insecticides in the malaria vector Anopheles gambiae.

Ingham VA, Pignatelli P, Moore JD, Wagstaff S, Ranson H.

BMC Genomics. 2017 Aug 30;18(1):669. doi: 10.1186/s12864-017-4086-7.

11.

A 'synthetic-sickness' screen for senescence re-engagement targets in mutant cancer backgrounds.

Cairney CJ, Godwin LS, Bilsland AE, Burns S, Stevenson KH, McGarry L, Revie J, Moore JD, Wiggins CM, Collinson RS, Mudd C, Tsonou E, Sadaie M, Bennett DC, Narita M, Torrance CJ, Keith WN.

PLoS Genet. 2017 Aug 14;13(8):e1006942. doi: 10.1371/journal.pgen.1006942. eCollection 2017 Aug.

12.

Evolutionary response to global change: Climate and land use interact to shape color polymorphism in a woodland salamander.

Cosentino BJ, Moore JD, Karraker NE, Ouellet M, Gibbs JP.

Ecol Evol. 2017 Jun 12;7(14):5426-5434. doi: 10.1002/ece3.3118. eCollection 2017 Jul.

13.

Episodic kinematics in continental rifts modulated by changes in mantle melt fraction.

Lamb S, Moore JDP, Smith E, Stern T.

Nature. 2017 Jul 5;547(7661):84-88. doi: 10.1038/nature22962.

PMID:
28682337
14.

Identification of extracellular glycerophosphodiesterases in Pseudomonas and their role in soil organic phosphorus remineralisation.

Lidbury IDEA, Murphy ARJ, Fraser TD, Bending GD, Jones AME, Moore JD, Goodall A, Tibbett M, Hammond JP, Scanlan DJ, Wellington EMH.

Sci Rep. 2017 May 19;7(1):2179. doi: 10.1038/s41598-017-02327-6.

15.

The 'known' genetic potential for microbial communities to degrade organic phosphorus is reduced in low-pH soils.

Lidbury IDEA, Fraser T, Murphy ARJ, Scanlan DJ, Bending GD, Jones AME, Moore JD, Goodall A, Tibbett M, Hammond JP, Wellington EMH.

Microbiologyopen. 2017 Aug;6(4). doi: 10.1002/mbo3.474. Epub 2017 Apr 16.

16.

Imaging the distribution of transient viscosity after the 2016 Mw 7.1 Kumamoto earthquake.

Moore JD, Yu H, Tang CH, Wang T, Barbot S, Peng D, Masuti S, Dauwels J, Hsu YJ, Lambert V, Nanjundiah P, Wei S, Lindsey E, Feng L, Shibazaki B.

Science. 2017 Apr 14;356(6334):163-167. doi: 10.1126/science.aal3422.

PMID:
28408598
17.

Coordination of Orofacial Motor Actions into Exploratory Behavior by Rat.

Kurnikova A, Moore JD, Liao SM, Deschênes M, Kleinfeld D.

Curr Biol. 2017 Mar 6;27(5):688-696. doi: 10.1016/j.cub.2017.01.013. Epub 2017 Feb 16.

18.

Application of Off-Rate Screening in the Identification of Novel Pan-Isoform Inhibitors of Pyruvate Dehydrogenase Kinase.

Brough PA, Baker L, Bedford S, Brown K, Chavda S, Chell V, D'Alessandro J, Davies NG, Davis B, Le Strat L, Macias AT, Maddox D, Mahon PC, Massey AJ, Matassova N, McKenna S, Meissner JW, Moore JD, Murray JB, Northfield CJ, Parry C, Parsons R, Roughley SD, Shaw T, Simmonite H, Stokes S, Surgenor A, Stefaniak E, Robertson A, Wang Y, Webb P, Whitehead N, Wood M.

J Med Chem. 2017 Mar 23;60(6):2271-2286. doi: 10.1021/acs.jmedchem.6b01478. Epub 2017 Feb 15.

PMID:
28199108
19.

Towards new sources of resistance to the currant-lettuce aphid (Nasonovia ribisnigri).

Walley PG, Hough G, Moore JD, Carder J, Elliott M, Mead A, Jones J, Teakle G, Barker G, Buchanan-Wollaston V, Hand P, Pink D, Collier R.

Mol Breed. 2017;37(1):4. doi: 10.1007/s11032-016-0606-4. Epub 2017 Jan 3.

20.

BTB-BACK Domain Protein POB1 Suppresses Immune Cell Death by Targeting Ubiquitin E3 ligase PUB17 for Degradation.

Orosa B, He Q, Mesmar J, Gilroy EM, McLellan H, Yang C, Craig A, Bailey M, Zhang C, Moore JD, Boevink PC, Tian Z, Birch PR, Sadanandom A.

PLoS Genet. 2017 Jan 5;13(1):e1006540. doi: 10.1371/journal.pgen.1006540. eCollection 2017 Jan.

21.

Multigenetic characterization of 'Candidatus Xenohaliotis californiensis'.

Cicala F, Moore JD, Cáceres-Martínez J, Del Río-Portilla MA, Hernández-Rodríguez M, Vásquez-Yeomans R, Rocha-Olivares A.

Int J Syst Evol Microbiol. 2017 Jan;67(1):42-49. doi: 10.1099/ijsem.0.001563. Epub 2017 Feb 20.

PMID:
27902186
22.

Adsorption, X-ray Diffraction, Photoelectron, and Atomic Emission Spectroscopy Benchmark Studies for the Eighth Industrial Fluid Properties Simulation Challenge.

Ross RB, Aeschliman DB, Ahmad R, Brennan JK, Brostrom ML, Frankel KA, Moore JD, Moore JD, Mountain RD, Poirier DM, Thommes M, Shen VK, Schultz NE, Siderius DW, Smith KD.

Adsorp Sci Technol. 2016 Feb;34(1):13-41. Epub 2016 Jan 27.

23.

The Eighth Industrial Fluids Properties Simulation Challenge.

Schultz NE, Ahmad R, Brennan JK, Frankel KA, Moore JD, Moore JD, Mountain RD, Ross RB, Thommes M, Shen VK, Siderius DW, Smith KD.

Adsorp Sci Technol. 2016 Feb;34(1):3-12.

24.

Identification of Unanticipated and Novel N-Acyl L-Homoserine Lactones (AHLs) Using a Sensitive Non-Targeted LC-MS/MS Method.

Patel NM, Moore JD, Blackwell HE, Amador-Noguez D.

PLoS One. 2016 Oct 5;11(10):e0163469. doi: 10.1371/journal.pone.0163469. eCollection 2016.

25.

Increasing the performance of pooled CRISPR-Cas9 drop-out screening.

Cross BC, Lawo S, Archer CR, Hunt JR, Yarker JL, Riccombeni A, Little AS, McCarthy NJ, Moore JD.

Sci Rep. 2016 Aug 22;6:31782. doi: 10.1038/srep31782.

26.

Does selection for gamete dispersal and capture lead to a sex difference in clump water-holding capacity?

Moore JD, Kollar LM, McLetchie DN.

Am J Bot. 2016 Aug;103(8):1449-57. doi: 10.3732/ajb.1600096. Epub 2016 Aug 18.

27.

Synthetic Lethal Targeting of ARID1A-Mutant Ovarian Clear Cell Tumors with Dasatinib.

Miller RE, Brough R, Bajrami I, Williamson CT, McDade S, Campbell J, Kigozi A, Rafiq R, Pemberton H, Natrajan R, Joel J, Astley H, Mahoney C, Moore JD, Torrance C, Gordan JD, Webber JT, Levin RS, Shokat KM, Bandyopadhyay S, Lord CJ, Ashworth A.

Mol Cancer Ther. 2016 Jul;15(7):1472-84. doi: 10.1158/1535-7163.MCT-15-0554. Epub 2016 Jun 30.

28.

Comparative genomic, proteomic and exoproteomic analyses of three Pseudomonas strains reveals novel insights into the phosphorus scavenging capabilities of soil bacteria.

Lidbury ID, Murphy AR, Scanlan DJ, Bending GD, Jones AM, Moore JD, Goodall A, Hammond JP, Wellington EM.

Environ Microbiol. 2016 Oct;18(10):3535-3549. doi: 10.1111/1462-2920.13390. Epub 2016 Jul 7.

29.

Inhibition, Not Excitation, Drives Rhythmic Whisking.

Deschênes M, Takatoh J, Kurnikova A, Moore JD, Demers M, Elbaz M, Furuta T, Wang F, Kleinfeld D.

Neuron. 2016 Apr 20;90(2):374-87. doi: 10.1016/j.neuron.2016.03.007. Epub 2016 Mar 31.

30.

Durability of Olyset campaign nets distributed between 2009 and 2011 in eight districts of Tanzania.

Massue DJ, Moore SJ, Mageni ZD, Moore JD, Bradley J, Pigeon O, Maziba EJ, Mandike R, Kramer K, Kisinza WN, Overgaard HJ, Lorenz LM.

Malar J. 2016 Mar 18;15:176. doi: 10.1186/s12936-016-1225-6.

31.

A coarse-grain force field for RDX: Density dependent and energy conserving.

Moore JD, Barnes BC, Izvekov S, Lísal M, Sellers MS, Taylor DE, Brennan JK.

J Chem Phys. 2016 Mar 14;144(10):104501. doi: 10.1063/1.4942520.

PMID:
26979691
32.

Comparative performance of three experimental hut designs for measuring malaria vector responses to insecticides in Tanzania.

Massue DJ, Kisinza WN, Malongo BB, Mgaya CS, Bradley J, Moore JD, Tenu FF, Moore SJ.

Malar J. 2016 Mar 15;15:165. doi: 10.1186/s12936-016-1221-x.

33.

Time-Series Transcriptomics Reveals That AGAMOUS-LIKE22 Affects Primary Metabolism and Developmental Processes in Drought-Stressed Arabidopsis.

Bechtold U, Penfold CA, Jenkins DJ, Legaie R, Moore JD, Lawson T, Matthews JS, Vialet-Chabrand SR, Baxter L, Subramaniam S, Hickman R, Florance H, Sambles C, Salmon DL, Feil R, Bowden L, Hill C, Baker NR, Lunn JE, Finkenstädt B, Mead A, Buchanan-Wollaston V, Beynon J, Rand DA, Wild DL, Denby KJ, Ott S, Smirnoff N, Mullineaux PM.

Plant Cell. 2016 Feb;28(2):345-66. doi: 10.1105/tpc.15.00910. Epub 2016 Feb 3.

34.

Impacts of Pristine and Transformed Ag and Cu Engineered Nanomaterials on Surficial Sediment Microbial Communities Appear Short-Lived.

Moore JD, Stegemeier JP, Bibby K, Marinakos SM, Lowry GV, Gregory KB.

Environ Sci Technol. 2016 Mar 1;50(5):2641-51. doi: 10.1021/acs.est.5b05054. Epub 2016 Feb 18.

PMID:
26841726
35.

Unpacking Payment Bundles.

Moore JD.

Phys Ther. 2016 Feb;96(2):139-41. doi: 10.2522/ptj.2016.96.2.139. No abstract available.

PMID:
26833117
36.

Pre-clinical use of isogenic cell lines and tumours in vitro and in vivo for predictive biomarker discovery; impact of KRAS and PI3KCA mutation status on MEK inhibitor activity is model dependent.

Haagensen EJ, Thomas HD, Mudd C, Tsonou E, Wiggins CM, Maxwell RJ, Moore JD, Newell DR.

Eur J Cancer. 2016 Mar;56:69-76. doi: 10.1016/j.ejca.2015.12.012. Epub 2016 Jan 25.

PMID:
26820797
37.
38.

The Role of Statin Therapy in Hemorrhagic Stroke.

Sikora Newsome A, Casciere BC, Jordan JD, Rhoney DH, Sullivan KA, Morbitzer KA, Moore JD, Durr EA.

Pharmacotherapy. 2015 Dec;35(12):1152-63. doi: 10.1002/phar.1674. Review.

PMID:
26684555
39.

A Medium-Throughput Single Cell CRISPR-Cas9 Assay to Assess Gene Essentiality.

Grassian AR, Scales TME, Knutson SK, Kuntz KW, McCarthy NJ, Lowe CE, Moore JD, Copeland RA, Keilhack H, Smith JJ, Wickenden JA, Ribich S.

Biol Proced Online. 2015 Nov 14;17:15. doi: 10.1186/s12575-015-0028-4. eCollection 2015.

40.

A Comparative Analysis of Synthetic Quorum Sensing Modulators in Pseudomonas aeruginosa: New Insights into Mechanism, Active Efflux Susceptibility, Phenotypic Response, and Next-Generation Ligand Design.

Moore JD, Rossi FM, Welsh MA, Nyffeler KE, Blackwell HE.

J Am Chem Soc. 2015 Nov 25;137(46):14626-39. doi: 10.1021/jacs.5b06728. Epub 2015 Nov 11.

41.

Potent and Selective Modulation of the RhlR Quorum Sensing Receptor by Using Non-native Ligands: An Emerging Target for Virulence Control in Pseudomonas aeruginosa.

Eibergen NR, Moore JD, Mattmann ME, Blackwell HE.

Chembiochem. 2015 Nov 2;16(16):2348-56. doi: 10.1002/cbic.201500357. Epub 2015 Oct 13.

42.

Loss of Endometrial Plasticity in Recurrent Pregnancy Loss.

Lucas ES, Dyer NP, Murakami K, Lee YH, Chan YW, Grimaldi G, Muter J, Brighton PJ, Moore JD, Patel G, Chan JK, Takeda S, Lam EW, Quenby S, Ott S, Brosens JJ.

Stem Cells. 2016 Feb;34(2):346-56. doi: 10.1002/stem.2222. Epub 2015 Dec 17.

43.

Vibrissa Self-Motion and Touch Are Reliably Encoded along the Same Somatosensory Pathway from Brainstem through Thalamus.

Moore JD, Mercer Lindsay N, Deschênes M, Kleinfeld D.

PLoS Biol. 2015 Sep 22;13(9):e1002253. doi: 10.1371/journal.pbio.1002253. eCollection 2015.

44.
45.

The Brainstem Oscillator for Whisking and the Case for Breathing as the Master Clock for Orofacial Motor Actions.

Kleinfeld D, Moore JD, Wang F, Deschênes M.

Cold Spring Harb Symp Quant Biol. 2014;79:29-39. doi: 10.1101/sqb.2014.79.024794. Epub 2015 Apr 15.

46.

Fluorescently labeled peptide increases identification of degenerated facial nerve branches during surgery and improves functional outcome.

Hussain T, Mastrodimos MB, Raju SC, Glasgow HL, Whitney M, Friedman B, Moore JD, Kleinfeld D, Steinbach P, Messer K, Pu M, Tsien RY, Nguyen QT.

PLoS One. 2015 Mar 9;10(3):e0119600. doi: 10.1371/journal.pone.0119600. eCollection 2015.

47.

Implementation of linear sensory signaling via multiple coordinated mechanisms at central vestibular nerve synapses.

McElvain LE, Faulstich M, Jeanne JM, Moore JD, du Lac S.

Neuron. 2015 Mar 4;85(5):1132-44. doi: 10.1016/j.neuron.2015.01.017. Epub 2015 Feb 19.

48.

Small molecule disruption of quorum sensing cross-regulation in pseudomonas aeruginosa causes major and unexpected alterations to virulence phenotypes.

Welsh MA, Eibergen NR, Moore JD, Blackwell HE.

J Am Chem Soc. 2015 Feb 4;137(4):1510-9. doi: 10.1021/ja5110798. Epub 2015 Jan 22.

49.

The clock protein period 2 synchronizes mitotic expansion and decidual transformation of human endometrial stromal cells.

Muter J, Lucas ES, Chan YW, Brighton PJ, Moore JD, Lacey L, Quenby S, Lam EW, Brosens JJ.

FASEB J. 2015 Apr;29(4):1603-14. doi: 10.1096/fj.14-267195. Epub 2015 Jan 8.

50.

The impact of CRISPR-Cas9 on target identification and validation.

Moore JD.

Drug Discov Today. 2015 Apr;20(4):450-7. doi: 10.1016/j.drudis.2014.12.016. Epub 2015 Jan 5. Review.

PMID:
25572406

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