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Items: 1 to 50 of 93

1.

MIP-MAP: High-Throughput Mapping of Caenorhabditis elegans Temperature-Sensitive Mutants via Molecular Inversion Probes.

Mok CA, Au V, Thompson OA, Edgley ML, Gevirtzman L, Yochem J, Lowry J, Memar N, Wallenfang MR, Rasoloson D, Bowerman B, Schnabel R, Seydoux G, Moerman DG, Waterston RH.

Genetics. 2017 Oct;207(2):447-463. doi: 10.1534/genetics.117.300179. Epub 2017 Aug 21.

2.

Mitochondrial Mutation Rate, Spectrum and Heteroplasmy in Caenorhabditis elegans Spontaneous Mutation Accumulation Lines of Differing Population Size.

Konrad A, Thompson O, Waterston RH, Moerman DG, Keightley PD, Bergthorsson U, Katju V.

Mol Biol Evol. 2017 Jun 1;34(6):1319-1334. doi: 10.1093/molbev/msx051.

PMID:
28087770
3.

Accelerating Gene Discovery by Phenotyping Whole-Genome Sequenced Multi-mutation Strains and Using the Sequence Kernel Association Test (SKAT).

Timbers TA, Garland SJ, Mohan S, Flibotte S, Edgley M, Muncaster Q, Au V, Li-Leger E, Rosell FI, Cai J, Rademakers S, Jansen G, Moerman DG, Leroux MR.

PLoS Genet. 2016 Aug 10;12(8):e1006235. doi: 10.1371/journal.pgen.1006235. eCollection 2016 Aug.

4.

UBR-5, a Conserved HECT-Type E3 Ubiquitin Ligase, Negatively Regulates Notch-Type Signaling in Caenorhabditis elegans.

Safdar K, Gu A, Xu X, Au V, Taylor J, Flibotte S, Moerman DG, Maine EM.

G3 (Bethesda). 2016 Jul 7;6(7):2125-34. doi: 10.1534/g3.116.027805.

5.

Rapid Increase in frequency of gene copy-number variants during experimental evolution in Caenorhabditis elegans.

Farslow JC, Lipinski KJ, Packard LB, Edgley ML, Taylor J, Flibotte S, Moerman DG, Katju V, Bergthorsson U.

BMC Genomics. 2015 Dec 9;16:1044. doi: 10.1186/s12864-015-2253-2.

6.

Chromoanasynthetic Genomic Rearrangement Identified in a N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Screen in Caenorhabditis elegans.

Itani OA, Flibotte S, Dumas KJ, Moerman DG, Hu PJ.

G3 (Bethesda). 2015 Dec 1;6(2):351-6. doi: 10.1534/g3.115.024257.

7.
8.

Remarkably Divergent Regions Punctuate the Genome Assembly of the Caenorhabditis elegans Hawaiian Strain CB4856.

Thompson OA, Snoek LB, Nijveen H, Sterken MG, Volkers RJ, Brenchley R, Van't Hof A, Bevers RP, Cossins AR, Yanai I, Hajnal A, Schmid T, Perkins JD, Spencer D, Kruglyak L, Andersen EC, Moerman DG, Hillier LW, Kammenga JE, Waterston RH.

Genetics. 2015 Jul;200(3):975-89. doi: 10.1534/genetics.115.175950. Epub 2015 May 19.

9.

Sarcomeres Pattern Proprioceptive Sensory Dendritic Endings through UNC-52/Perlecan in C. elegans.

Liang X, Dong X, Moerman DG, Shen K, Wang X.

Dev Cell. 2015 May 26;33(4):388-400. doi: 10.1016/j.devcel.2015.03.010. Epub 2015 May 14.

10.

Spectrum of variations in dog-1/FANCJ and mdf-1/MAD1 defective Caenorhabditis elegans strains after long-term propagation.

Tarailo-Graovac M, Wong T, Qin Z, Flibotte S, Taylor J, Moerman DG, Rose AM, Chen N.

BMC Genomics. 2015 Mar 18;16:210. doi: 10.1186/s12864-015-1402-y.

11.

Cyclin B3 and dynein heavy chain cooperate to increase fitness in the absence of mdf-1/MAD1 in Caenorhabditis elegans.

Tarailo-Graovac M, Wong T, Qin Z, Flibotte S, Taylor J, Moerman DG, Rose AM, Chen N.

Cell Cycle. 2014;13(19):3089-199. doi: 10.4161/15384101.2014.949491.

12.

Random and targeted transgene insertion in Caenorhabditis elegans using a modified Mos1 transposon.

Frøkjær-Jensen C, Davis MW, Sarov M, Taylor J, Flibotte S, LaBella M, Pozniakovsky A, Moerman DG, Jorgensen EM.

Nat Methods. 2014 May;11(5):529-34. doi: 10.1038/nmeth.2889. Epub 2014 Mar 16.

13.

Gap junctions in C. elegans.

Simonsen KT, Moerman DG, Naus CC.

Front Physiol. 2014 Feb 11;5:40. doi: 10.3389/fphys.2014.00040. eCollection 2014. Review.

14.

A network of HSPG core proteins and HS modifying enzymes regulates netrin-dependent guidance of D-type motor neurons in Caenorhabditis elegans.

Gysi S, Rhiner C, Flibotte S, Moerman DG, Hengartner MO.

PLoS One. 2013 Sep 16;8(9):e74908. doi: 10.1371/journal.pone.0074908. eCollection 2013.

15.

The million mutation project: a new approach to genetics in Caenorhabditis elegans.

Thompson O, Edgley M, Strasbourger P, Flibotte S, Ewing B, Adair R, Au V, Chaudhry I, Fernando L, Hutter H, Kieffer A, Lau J, Lee N, Miller A, Raymant G, Shen B, Shendure J, Taylor J, Turner EH, Hillier LW, Moerman DG, Waterston RH.

Genome Res. 2013 Oct;23(10):1749-62. doi: 10.1101/gr.157651.113. Epub 2013 Jun 25.

16.

Unexpected role for dosage compensation in the control of dauer arrest, insulin-like signaling, and FoxO transcription factor activity in Caenorhabditis elegans.

Dumas KJ, Delaney CE, Flibotte S, Moerman DG, Csankovszki G, Hu PJ.

Genetics. 2013 Jul;194(3):619-29. doi: 10.1534/genetics.113.149948. Epub 2013 Jun 3.

17.

Chromosome movements promoted by the mitochondrial protein SPD-3 are required for homology search during Caenorhabditis elegans meiosis.

Labrador L, Barroso C, Lightfoot J, Müller-Reichert T, Flibotte S, Taylor J, Moerman DG, Villeneuve AM, Martinez-Perez E.

PLoS Genet. 2013 May;9(5):e1003497. doi: 10.1371/journal.pgen.1003497. Epub 2013 May 9.

18.

The C. elegans CDK8 Mediator module regulates axon guidance decisions in the ventral nerve cord and during dorsal axon navigation.

Steimel A, Suh J, Hussainkhel A, Deheshi S, Grants JM, Zapf R, Moerman DG, Taubert S, Hutter H.

Dev Biol. 2013 May 15;377(2):385-98. doi: 10.1016/j.ydbio.2013.02.009. Epub 2013 Feb 28.

19.

CPNA-1, a copine domain protein, is located at integrin adhesion sites and is required for myofilament stability in Caenorhabditis elegans.

Warner A, Xiong G, Qadota H, Rogalski T, Vogl AW, Moerman DG, Benian GM.

Mol Biol Cell. 2013 Mar;24(5):601-16. doi: 10.1091/mbc.E12-06-0478. Epub 2013 Jan 2.

20.

Genetic control of vulval development in Caenorhabditis briggsae.

Sharanya D, Thillainathan B, Marri S, Bojanala N, Taylor J, Flibotte S, Moerman DG, Waterston RH, Gupta BP.

G3 (Bethesda). 2012 Dec;2(12):1625-41. doi: 10.1534/g3.112.004598. Epub 2012 Dec 1.

21.

A molecular mechanism for the requirement of PAT-4 (integrin-linked kinase (ILK)) for the localization of UNC-112 (Kindlin) to integrin adhesion sites.

Qadota H, Moerman DG, Benian GM.

J Biol Chem. 2012 Aug 17;287(34):28537-51. doi: 10.1074/jbc.M112.354852. Epub 2012 Jul 3.

22.

Membrane extensions are associated with proper anterior migration of muscle cells during Caenorhabditis elegans embryogenesis.

Viveiros R, Hutter H, Moerman DG.

Dev Biol. 2011 Oct 1;358(1):189-200. doi: 10.1016/j.ydbio.2011.07.026. Epub 2011 Jul 23.

23.

The Caenorhabditis elegans paxillin orthologue, PXL-1, is required for pharyngeal muscle contraction and for viability.

Warner A, Qadota H, Benian GM, Vogl AW, Moerman DG.

Mol Biol Cell. 2011 Jul 15;22(14):2551-63. doi: 10.1091/mbc.E10-12-0941. Epub 2011 Jun 1.

24.

Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle.

Meissner B, Rogalski T, Viveiros R, Warner A, Plastino L, Lorch A, Granger L, Segalat L, Moerman DG.

PLoS One. 2011;6(5):e19937. doi: 10.1371/journal.pone.0019937. Epub 2011 May 17.

25.

DNA synthesis generates terminal duplications that seal end-to-end chromosome fusions.

Lowden MR, Flibotte S, Moerman DG, Ahmed S.

Science. 2011 Apr 22;332(6028):468-71. doi: 10.1126/science.1199022.

26.

Muscle: Structure, Function, and Development.

Moerman DG, Fire A.

In: Riddle DL, Blumenthal T, Meyer BJ, Priess JR, editors. C. elegans II. 2nd edition. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 1997. No abstract available. Chapter 16.

27.

C. elegans ADAMTS ADT-2 regulates body size by modulating TGFβ signaling and cuticle collagen organization.

Fernando T, Flibotte S, Xiong S, Yin J, Yzeiraj E, Moerman DG, Meléndez A, Savage-Dunn C.

Dev Biol. 2011 Apr 1;352(1):92-103. doi: 10.1016/j.ydbio.2011.01.016. Epub 2011 Jan 21.

28.

Identifying novel genes in C. elegans using SAGE tags.

Nesbitt MJ, Moerman DG, Chen N.

BMC Mol Biol. 2010 Dec 10;11:96. doi: 10.1186/1471-2199-11-96.

29.

Whole-genome profiling of mutagenesis in Caenorhabditis elegans.

Flibotte S, Edgley ML, Chaudhry I, Taylor J, Neil SE, Rogula A, Zapf R, Hirst M, Butterfield Y, Jones SJ, Marra MA, Barstead RJ, Moerman DG.

Genetics. 2010 Jun;185(2):431-41. doi: 10.1534/genetics.110.116616. Epub 2010 May 3.

30.

Targeted gene deletions in C. elegans using transposon excision.

Frøkjaer-Jensen C, Davis MW, Hollopeter G, Taylor J, Harris TW, Nix P, Lofgren R, Prestgard-Duke M, Bastiani M, Moerman DG, Jorgensen EM.

Nat Methods. 2010 Jun;7(6):451-3. doi: 10.1038/nmeth.1454. Epub 2010 Apr 25.

31.

Characterization of the astacin family of metalloproteases in C. elegans.

Park JO, Pan J, Möhrlen F, Schupp MO, Johnsen R, Baillie DL, Zapf R, Moerman DG, Hutter H.

BMC Dev Biol. 2010 Jan 28;10:14. doi: 10.1186/1471-213X-10-14.

32.

Copy number variation in the genomes of twelve natural isolates of Caenorhabditis elegans.

Maydan JS, Lorch A, Edgley ML, Flibotte S, Moerman DG.

BMC Genomics. 2010 Jan 25;11:62. doi: 10.1186/1471-2164-11-62.

33.

New tools for investigating the comparative biology of Caenorhabditis briggsae and C. elegans.

Zhao Z, Flibotte S, Murray JI, Blick D, Boyle TJ, Gupta B, Moerman DG, Waterston RH.

Genetics. 2010 Mar;184(3):853-63. doi: 10.1534/genetics.109.110270. Epub 2009 Dec 14.

34.

An integrated strategy to study muscle development and myofilament structure in Caenorhabditis elegans.

Meissner B, Warner A, Wong K, Dube N, Lorch A, McKay SJ, Khattra J, Rogalski T, Somasiri A, Chaudhry I, Fox RM, Miller DM 3rd, Baillie DL, Holt RA, Jones SJ, Marra MA, Moerman DG.

PLoS Genet. 2009 Jun;5(6):e1000537. doi: 10.1371/journal.pgen.1000537. Epub 2009 Jun 26.

35.

Identification of genes expressed in the hermaphrodite germ line of C. elegans using SAGE.

Wang X, Zhao Y, Wong K, Ehlers P, Kohara Y, Jones SJ, Marra MA, Holt RA, Moerman DG, Hansen D.

BMC Genomics. 2009 May 9;10:213. doi: 10.1186/1471-2164-10-213.

36.

Cis-regulatory mutations in the Caenorhabditis elegans homeobox gene locus cog-1 affect neuronal development.

O'Meara MM, Bigelow H, Flibotte S, Etchberger JF, Moerman DG, Hobert O.

Genetics. 2009 Apr;181(4):1679-86. doi: 10.1534/genetics.108.097832. Epub 2009 Feb 2.

37.

De Novo identification of single nucleotide mutations in Caenorhabditis elegans using array comparative genomic hybridization.

Maydan JS, Okada HM, Flibotte S, Edgley ML, Moerman DG.

Genetics. 2009 Apr;181(4):1673-7. doi: 10.1534/genetics.108.100065. Epub 2009 Feb 2.

38.

ELT-2 is the predominant transcription factor controlling differentiation and function of the C. elegans intestine, from embryo to adult.

McGhee JD, Fukushige T, Krause MW, Minnema SE, Goszczynski B, Gaudet J, Kohara Y, Bossinger O, Zhao Y, Khattra J, Hirst M, Jones SJ, Marra MA, Ruzanov P, Warner A, Zapf R, Moerman DG, Kalb JM.

Dev Biol. 2009 Mar 15;327(2):551-65. doi: 10.1016/j.ydbio.2008.11.034. Epub 2008 Dec 9.

39.

Rapid high resolution single nucleotide polymorphism-comparative genome hybridization mapping in Caenorhabditis elegans.

Flibotte S, Edgley ML, Maydan J, Taylor J, Zapf R, Waterston R, Moerman DG.

Genetics. 2009 Jan;181(1):33-7. doi: 10.1534/genetics.108.096487. Epub 2008 Oct 28.

40.
41.

Transcriptome analysis for Caenorhabditis elegans based on novel expressed sequence tags.

Shin H, Hirst M, Bainbridge MN, Magrini V, Mardis E, Moerman DG, Marra MA, Baillie DL, Jones SJ.

BMC Biol. 2008 Jul 8;6:30. doi: 10.1186/1741-7007-6-30.

42.

Towards a mutation in every gene in Caenorhabditis elegans.

Moerman DG, Barstead RJ.

Brief Funct Genomic Proteomic. 2008 May;7(3):195-204. doi: 10.1093/bfgp/eln016. Epub 2008 Apr 16. Review.

PMID:
18417533
43.

Sarcomere assembly in C. elegans muscle.

Moerman DG, Williams BD.

WormBook. 2006 Jan 16:1-16. Review.

45.

High-throughput in vivo analysis of gene expression in Caenorhabditis elegans.

Hunt-Newbury R, Viveiros R, Johnsen R, Mah A, Anastas D, Fang L, Halfnight E, Lee D, Lin J, Lorch A, McKay S, Okada HM, Pan J, Schulz AK, Tu D, Wong K, Zhao Z, Alexeyenko A, Burglin T, Sonnhammer E, Schnabel R, Jones SJ, Marra MA, Baillie DL, Moerman DG.

PLoS Biol. 2007 Sep;5(9):e237.

46.

Identification and analysis of internal promoters in Caenorhabditis elegans operons.

Huang P, Pleasance ED, Maydan JS, Hunt-Newbury R, O'Neil NJ, Mah A, Baillie DL, Marra MA, Moerman DG, Jones SJ.

Genome Res. 2007 Oct;17(10):1478-85. Epub 2007 Aug 21.

47.

Establishment of a tissue-specific RNAi system in C. elegans.

Qadota H, Inoue M, Hikita T, Köppen M, Hardin JD, Amano M, Moerman DG, Kaibuchi K.

Gene. 2007 Oct 1;400(1-2):166-73. Epub 2007 Aug 3.

48.

UNC-97/PINCH is involved in the assembly of integrin cell adhesion complexes in Caenorhabditis elegans body wall muscle.

Norman KR, Cordes S, Qadota H, Rahmani P, Moerman DG.

Dev Biol. 2007 Sep 1;309(1):45-55. Epub 2007 Jun 22.

49.

The molecular signature and cis-regulatory architecture of a C. elegans gustatory neuron.

Etchberger JF, Lorch A, Sleumer MC, Zapf R, Jones SJ, Marra MA, Holt RA, Moerman DG, Hobert O.

Genes Dev. 2007 Jul 1;21(13):1653-74.

50.

Genome-scale analysis of in vivo spatiotemporal promoter activity in Caenorhabditis elegans.

Dupuy D, Bertin N, Hidalgo CA, Venkatesan K, Tu D, Lee D, Rosenberg J, Svrzikapa N, Blanc A, Carnec A, Carvunis AR, Pulak R, Shingles J, Reece-Hoyes J, Hunt-Newbury R, Viveiros R, Mohler WA, Tasan M, Roth FP, Le Peuch C, Hope IA, Johnsen R, Moerman DG, Barabási AL, Baillie D, Vidal M.

Nat Biotechnol. 2007 Jun;25(6):663-8. Epub 2007 May 7.

PMID:
17486083

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