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Change of the 5α/5β ratio of urinary steroid metabolites in benign prostatic hyperplasia patients treated with dutasteride.

Maeda T, Kikuchi E, Hasegawa M, Homma K, Yasumizu Y, Hattori S, Kosaka T, Shinoda K, Miyajima A, Oya M.

Clin Biochem. 2018 Mar 31. pii: S0009-9120(17)31100-1. doi: 10.1016/j.clinbiochem.2018.03.021. [Epub ahead of print]


Novel application of three-dimensional shear wave elastography in the detection of clinically significant prostate cancer.

Shoji S, Hashimoto A, Nakamura T, Hiraiwa S, Sato H, Sato Y, Tajiri T, Miyajima A.

Biomed Rep. 2018 Apr;8(4):373-377. doi: 10.3892/br.2018.1059. Epub 2018 Feb 7.


Vasohibin-1 as a novel microenvironmental biomarker for patient risk reclassification in low-risk prostate cancer.

Kobayashi H, Kosaka T, Mikami S, Miyazaki Y, Matsumoto K, Kikuchi E, Miyajima A, Kameyama K, Sato Y, Oya M.

Oncotarget. 2017 Dec 7;9(12):10203-10210. doi: 10.18632/oncotarget.23011. eCollection 2018 Feb 13.


Verification of the International Society of Urological Pathology recommendations in Japanese patients with clear cell renal cell carcinoma.

Kim H, Inomoto C, Uchida T, Furuya H, Komiyama T, Kajiwara H, Kobayashi H, Nakamura N, Miyajima A.

Int J Oncol. 2018 Apr;52(4):1139-1148. doi: 10.3892/ijo.2018.4294. Epub 2018 Feb 28.


The transcription factor Klf5 is essential for intrahepatic biliary epithelial tissue remodeling after cholestatic liver injury.

Okada H, Yamada M, Kamimoto K, Kok CY, Kaneko K, Ema M, Miyajima A, Itoh T.

J Biol Chem. 2018 Mar 9. pii: jbc.RA118.002372. doi: 10.1074/jbc.RA118.002372. [Epub ahead of print]


Two-stage resection of a bilateral pheochromocytoma and pancreatic neuroendocrine tumor in a patient with von Hippel-Lindau disease: A case report.

Endo Y, Kitago M, Miyajima A, Kurihara I, Kameyama K, Shinoda M, Yagi H, Abe Y, Hibi T, Takagi C, Nakano Y, Koizumi W, Itano O, Kitagawa Y.

Int J Surg Case Rep. 2018;44:139-142. doi: 10.1016/j.ijscr.2018.02.020. Epub 2018 Feb 16.


Portal fibroblasts marked by the surface antigen Thy1 contribute to fibrosis in mouse models of cholestatic liver injury.

Katsumata LW, Miyajima A, Itoh T.

Hepatol Commun. 2017 Mar 22;1(3):198-214. doi: 10.1002/hep4.1023. eCollection 2017 May.


[Sixteen Cases of Colon Stenting as a Bridge to Surgery(BTS)for Obstructive Colorectal Cancer].

Otsuka R, Saito S, Hirayama R, Miura Y, Sasaki K, Miyajima A, Kuwamoto N, Kataoka R, Shindo Y, Fujita R.

Gan To Kagaku Ryoho. 2017 Nov;44(12):1946-1948. Japanese.


Round robin study to evaluate the reconstructed human epidermis (RhE) model as an in vitro skin irritation test for detection of irritant activity in medical device extracts.

De Jong WH, Hoffmann S, Lee M, Kandárová H, Pellevoisin C, Haishima Y, Rollins B, Zdawczyk A, Willoughby J, Bachelor M, Schatz T, Skoog S, Parker S, Sawyer A, Pescio P, Fant K, Kim KM, Kwon JS, Gehrke H, Hofman-Hüther H, Meloni M, Julius C, Briotet D, Letasiova S, Kato R, Miyajima A, De La Fonteyne LJJ, Videau C, Tornier C, Turley AP, Christiano N, Rollins TS, Coleman KP.

Toxicol In Vitro. 2018 Jan 8. pii: S0887-2333(18)30001-8. doi: 10.1016/j.tiv.2018.01.001. [Epub ahead of print] No abstract available.


Pre-operative and post-operative estimated glomerular filtration rate in Japanese patients with urological malignancies.

Niwa N, Yoshida T, Mizuno R, Kikuchi E, Miyajima A, Hayashi M, Oya M.

Clin Exp Nephrol. 2017 Nov 27. doi: 10.1007/s10157-017-1509-3. [Epub ahead of print]


Reactive oxygen species induction by cabazitaxel through inhibiting Sestrin-3 in castration resistant prostate cancer.

Kosaka T, Hongo H, Miyazaki Y, Nishimoto K, Miyajima A, Oya M.

Oncotarget. 2017 Sep 21;8(50):87675-87683. doi: 10.18632/oncotarget.21147. eCollection 2017 Oct 20.


Factors influencing the operating time for single-port laparoscopic radical nephrectomy: focus on the anatomy and distribution of the renal artery and vein.

Matsumoto K, Miyajima A, Fukumoto K, Komatsuda A, Niwa N, Hattori S, Takeda T, Kikuchi E, Asanuma H, Oya M.

Jpn J Clin Oncol. 2017 Oct 1;47(10):976-980. doi: 10.1093/jjco/hyx105.


Influence of dutasteride treatment on serum hormone levels and aging male symptoms in patients with benign prostatic enlargement.

Maeda T, Kikuchi E, Hasegawa M, Homma K, Ando T, Suzuki K, Kaneko G, Mizuno R, Miyajima A, Oya M.

Int J Urol. 2018 Jan;25(1):70-74. doi: 10.1111/iju.13470. Epub 2017 Oct 3.


Secondary Adrenal Insufficiency Following Nivolumab Therapy in a Patient with Metastatic Renal Cell Carcinoma.

Seki T, Yasuda A, Oki M, Kitajima N, Takagi A, Nakajima N, Miyajima A, Fukagawa M.

Tokai J Exp Clin Med. 2017 Sep 20;42(3):115-120.


Three-flap umbilicoplasty: a novel and preliminary method of laparoendoscopic single-site transumbilical surgical approach for urachal remnants.

Kim H, Nakajima S, Kawamura Y, Shoji S, Hoshi A, Uchida T, Terachi T, Miyajima A.

Int Urol Nephrol. 2017 Nov;49(11):1965-1971. doi: 10.1007/s11255-017-1678-8. Epub 2017 Aug 21.


Thyrotoxic rubber antioxidants, 2-mercaptobenzimidazole and its methyl derivatives, cause both inhibition and induction of drug-metabolizing activity in rat liver microsomes after repeated oral administration.

Miyajima A, Sakemi-Hoshikawa K, Usami M, Mitsunaga K, Irie T, Ohno Y, Sunouchi M.

Biochem Biophys Res Commun. 2017 Oct 7;492(1):116-120. doi: 10.1016/j.bbrc.2017.08.024. Epub 2017 Aug 9.


Identification of the novel 3' UTR sequences of human IL-21 mRNA as potential targets of miRNAs.

Enomoto Y, Takagi R, Naito Y, Kiniwa T, Tanaka Y, Hamada-Tsutsumi S, Kawano M, Matsushita S, Ochiya T, Miyajima A.

Sci Rep. 2017 Aug 10;7(1):7780. doi: 10.1038/s41598-017-07853-x.


Erratum: YAP determines the cell fate of injured mouse hepatocytes in vivo.

Miyamura N, Hata S, Itoh T, Tanaka M, Nishio M, Itoh M, Ogawa Y, Terai S, Sakaida I, Suzuki A, Miyajima A, Nishina H.

Nat Commun. 2017 Aug 7;8:16146. doi: 10.1038/ncomms16146.


Oncostatin M causes liver fibrosis by regulating cooperation between hepatic stellate cells and macrophages in mice.

Matsuda M, Tsurusaki S, Miyata N, Saijou E, Okochi H, Miyajima A, Tanaka M.

Hepatology. 2018 Jan;67(1):296-312. doi: 10.1002/hep.29421. Epub 2017 Nov 15.


An In Vitro Human Liver Model by iPSC-Derived Parenchymal and Non-parenchymal Cells.

Koui Y, Kido T, Ito T, Oyama H, Chen SW, Katou Y, Shirahige K, Miyajima A.

Stem Cell Reports. 2017 Aug 8;9(2):490-498. doi: 10.1016/j.stemcr.2017.06.010. Epub 2017 Jul 27.


YAP determines the cell fate of injured mouse hepatocytes in vivo.

Miyamura N, Hata S, Itoh T, Tanaka M, Nishio M, Itoh M, Ogawa Y, Terai S, Sakaida I, Suzuki A, Miyajima A, Nishina H.

Nat Commun. 2017 Jul 6;8:16017. doi: 10.1038/ncomms16017. Erratum in: Nat Commun. 2017 Aug 07;8:16146.


The Conditional Survival with Time of Intravesical Recurrence of Upper Tract Urothelial Carcinoma.

Shigeta K, Kikuchi E, Hagiwara M, Ando T, Mizuno R, Abe T, Mikami S, Miyajima A, Nakagawa K, Oya M.

J Urol. 2017 Dec;198(6):1278-1285. doi: 10.1016/j.juro.2017.06.073. Epub 2017 Jun 17.


Prognostic significance of erythrocyte protein band 4.1-like5 expression in upper urinary tract urothelial carcinoma.

Daimon T, Kosaka T, Kikuchi E, Mikami S, Miyazaki Y, Hashimoto A, Hashimoto S, Mizuno R, Miyajima A, Okada Y, Sabe H, Oya M.

Urol Oncol. 2017 Sep;35(9):543.e17-543.e24. doi: 10.1016/j.urolonc.2017.04.008. Epub 2017 May 5.


Expression and localization of sterile alpha motif domain containing 5 is associated with cell type and malignancy of biliary tree.

Yagai T, Matsui S, Harada K, Inagaki FF, Saijou E, Miura Y, Nakanuma Y, Miyajima A, Tanaka M.

PLoS One. 2017 Apr 7;12(4):e0175355. doi: 10.1371/journal.pone.0175355. eCollection 2017.


Prolonged pneumoperitoneum time is an independent risk factor for intravesical recurrence after laparoscopic radical nephroureterectomy in upper tract urothelial carcinoma.

Shigeta K, Kikuchi E, Hagiwara M, Ando T, Mizuno R, Miyajima A, Nakagawa K, Oya M.

Surg Oncol. 2017 Mar;26(1):73-79. doi: 10.1016/j.suronc.2017.01.003. Epub 2017 Jan 23.


Obstructive sleep apnea syndrome should be considered as a cause of nocturia in younger patients without other voiding symptoms.

Maeda T, Fukunaga K, Nagata H, Haraguchi M, Kikuchi E, Miyajima A, Yamasawa W, Shirahama R, Narita M, Betsuyaku T, Asano K, Oya M.

Can Urol Assoc J. 2016 Jul-Aug;10(7-8):E241-E245. doi: 10.5489/cuaj.3508. Epub 2016 Jul 12.


Simple and practical nomograms for predicting the stone-free rate after shock wave lithotripsy in patients with a solitary upper ureteral stone.

Niwa N, Matsumoto K, Miyahara M, Omura M, Kobayashi H, Kikuchi E, Miyajima A, Miyata K, Oya M.

World J Urol. 2017 Sep;35(9):1455-1461. doi: 10.1007/s00345-017-2014-8. Epub 2017 Feb 20.


Impact of baseline visceral fat accumulation on prognosis in patients with metastatic renal cell carcinoma treated with systemic therapy.

Mizuno R, Miyajima A, Hibi T, Masuda A, Shinojima T, Kikuchi E, Jinzaki M, Oya M.

Med Oncol. 2017 Apr;34(4):47. doi: 10.1007/s12032-017-0908-3. Epub 2017 Feb 17.


Natural course of asymptomatic abnormal prostate findings incidentally detected by CT after intravesical BCG therapy.

Matsushima M, Kikuchi E, Akita H, Miyajima A, Oya M, Jinzaki M.

Int J Clin Oncol. 2017 Jun;22(3):554-562. doi: 10.1007/s10147-017-1096-z. Epub 2017 Feb 10.


Effects of Simvastatin on Alveolar Regeneration and Its Relationship to Exposure in Mice with Dexamethasone-Induced Emphysema.

Hirooka S, Ueno M, Fukuda S, Miyajima A, Hirota T.

Biol Pharm Bull. 2017;40(2):155-160. doi: 10.1248/bpb.b16-00637.


Characterizing intermediate-risk non-muscle-invasive bladder cancer: Implications for the definition of intermediate risk and treatment strategy.

Matsumoto K, Kikuchi E, Yanai Y, Hayakawa N, Ito Y, Maeda T, Nagata H, Miyajima A, Oya M.

Urol Oncol. 2017 May;35(5):208-214. doi: 10.1016/j.urolonc.2016.11.014. Epub 2017 Jan 3.


Influence of physician years on urological journal publication productivity among Japanese urologists.

Niwa N, Kikuchi E, Matsumoto K, Miyajima A, Oya M.

Springerplus. 2016 Nov 29;5(1):2040. eCollection 2016.


Comparison of the transcriptomic profile of hepatic human induced pluripotent stem like cells cultured in plates and in a 3D microscale dynamic environment.

Leclerc E, Kimura K, Shinohara M, Danoy M, Le Gall M, Kido T, Miyajima A, Fujii T, Sakai Y.

Genomics. 2017 Jan;109(1):16-26. doi: 10.1016/j.ygeno.2016.11.008. Epub 2016 Nov 29.


Y-box binding protein-1 promotes hepatocellular carcinoma-initiating cell progression and tumorigenesis via Wnt/β-catenin pathway.

Chao HM, Huang HX, Chang PH, Tseng KC, Miyajima A, Chern E.

Oncotarget. 2017 Jan 10;8(2):2604-2616. doi: 10.18632/oncotarget.13733.


Acquired platinum resistance involves epithelial to mesenchymal transition through ubiquitin ligase FBXO32 dysregulation.

Tanaka N, Kosaka T, Miyazaki Y, Mikami S, Niwa N, Otsuka Y, Minamishima YA, Mizuno R, Kikuchi E, Miyajima A, Sabe H, Okada Y, Uhlén P, Suematsu M, Oya M.

JCI Insight. 2016 Nov 3;1(18):e83654.


A Transcriptomic Signature of Mouse Liver Progenitor Cells.

Passman AM, Low J, London R, Tirnitz-Parker JE, Miyajima A, Tanaka M, Strick-Marchand H, Darlington GJ, Finch-Edmondson M, Ochsner S, Zhu C, Whelan J, Callus BA, Yeoh GC.

Stem Cells Int. 2016;2016:5702873. Epub 2016 Oct 3.


Liver regeneration and fibrosis after inflammation.

Tanaka M, Miyajima A.

Inflamm Regen. 2016 Oct 18;36:19. doi: 10.1186/s41232-016-0025-2. eCollection 2016. Review.


Pharmacokinetics of ivermectin applied topically by whole-body bathing method in healthy volunteers.

Miyajima A, Hirota T, Tashiro M, Noguchi W, Kawano Y, Hanawa T, Kigure A, Anata T, Yamamoto Y, Yuasa N, Koshino M, Shiraishi Y, Yuzawa K, Akagi K, Yoshimasu T, Makigami K, Komoda M.

J Dermatol. 2017 Apr;44(4):406-413. doi: 10.1111/1346-8138.13628. Epub 2016 Oct 15.


Novel algorithm for management of acute epididymitis.

Hongo H, Kikuchi E, Matsumoto K, Yazawa S, Kanao K, Kosaka T, Mizuno R, Miyajima A, Saito S, Oya M.

Int J Urol. 2017 Jan;24(1):82-87. doi: 10.1111/iju.13236. Epub 2016 Oct 6.


Laparoendoscopic single-site surgeries: A multicenter experience of 469 cases in Japan.

Sato F, Nakagawa K, Kawauchi A, Matsubara A, Okegawa T, Habuchi T, Yoshimura K, Hoshi A, Kinoshita H, Miyajima A, Naitoh Y, Inoue S, Itaya N, Narita S, Hanai K, Okubo K, Yanishi M, Matsuda T, Terachi T, Mimata H.

Int J Urol. 2017 Jan;24(1):69-74. doi: 10.1111/iju.13235. Epub 2016 Oct 4.


The Preoperative Neutrophil-to-lymphocyte Ratio is a Novel Biomarker for Predicting Worse Clinical Outcomes in Non-muscle Invasive Bladder Cancer Patients with a Previous History of Smoking.

Ogihara K, Kikuchi E, Yuge K, Yanai Y, Matsumoto K, Miyajima A, Asakura H, Oya M.

Ann Surg Oncol. 2016 Dec;23(Suppl 5):1039-1047. Epub 2016 Sep 22.


Urinary pH Levels are Strongly Associated with Bladder Recurrence After Nephroureterectomy in Upper Tract Urothelial Carcinoma Patients with a Smoking History.

Ide H, Kikuchi E, Hagiwara M, Hayakawa N, Hongo H, Miyajima A, Oya M.

Ann Surg Oncol. 2016 Dec;23(Suppl 5):1029-1038. Epub 2016 Sep 9.


Determining When to Stop Prostate Specific Antigen Monitoring after Radical Prostatectomy: the Role of Ultrasensitive Prostate Specific Antigen.

Matsumoto K, Komatsuda A, Yanai Y, Niwa N, Kosaka T, Mizuno R, Kikuchi E, Miyajima A, Oya M.

J Urol. 2017 Mar;197(3 Pt 1):655-661. doi: 10.1016/j.juro.2016.08.098. Epub 2016 Aug 30.


NK cells activated by Interleukin-4 in cooperation with Interleukin-15 exhibit distinctive characteristics.

Kiniwa T, Enomoto Y, Terazawa N, Omi A, Miyata N, Ishiwata K, Miyajima A.

Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):10139-44. doi: 10.1073/pnas.1600112113. Epub 2016 Aug 22.


Population differences in S-warfarin pharmacokinetics among African Americans, Asians and whites: their influence on pharmacogenetic dosing algorithms.

Kubo K, Ohara M, Tachikawa M, Cavallari LH, Lee MTM, Wen MS, Scordo MG, Nutescu EA, Perera MA, Miyajima A, Kaneko N, Pengo V, Padrini R, Chen YT, Takahashi H.

Pharmacogenomics J. 2017 Dec;17(6):494-500. doi: 10.1038/tpj.2016.57. Epub 2016 Aug 9.


Heterogeneity and stochastic growth regulation of biliary epithelial cells dictate dynamic epithelial tissue remodeling.

Kamimoto K, Kaneko K, Kok CY, Okada H, Miyajima A, Itoh T.

Elife. 2016 Jul 19;5. pii: e15034. doi: 10.7554/eLife.15034.


High Absolute Monocyte Count Predicts Poor Clinical Outcome in Patients with Castration-Resistant Prostate Cancer Treated with Docetaxel Chemotherapy.

Shigeta K, Kosaka T, Kitano S, Yasumizu Y, Miyazaki Y, Mizuno R, Shinojima T, Kikuchi E, Miyajima A, Tanoguchi H, Hasegawa S, Oya M.

Ann Surg Oncol. 2016 Nov;23(12):4115-4122. Epub 2016 Jun 30.


A Novel Wiring Technique to Insert a Retrograde Guidewire Directly Into the Antegrade Guiding Catheter at the Ascending Aorta for Retrograde Percutaneous Recanalization of an Ostial Coronary Total Occlusion.

Sekiguchi M, Taguchi T, Miyajima A, Hasegawa S, Yamazaki M, Kurabayashi M.

Int Heart J. 2016 Jul 27;57(4):503-6. doi: 10.1536/ihj.15-435. Epub 2016 Jun 29.


[Risk factors in localized prostate cancer].

Matsumoto K, Miyajima A, Oya M.

Nihon Rinsho. 2016 May 20;74 Suppl 3:161-5. Japanese. No abstract available.


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