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Items: 1 to 50 of 718

1.

Artificial intelligence in pharmaceutical research and development.

Mitchell JB.

Future Med Chem. 2018 Jul 3. doi: 10.4155/fmc-2018-0158. [Epub ahead of print] No abstract available.

PMID:
29966438
2.

Co-imaging of the tumor oxygenation and metabolism using electron paramagnetic resonance imaging and 13-C hyperpolarized magnetic resonance imaging before and after irradiation.

Matsuo M, Kawai T, Kishimoto S, Saito K, Munasinghe J, Devasahayam N, Mitchell JB, Krishna MC.

Oncotarget. 2018 May 18;9(38):25089-25100. doi: 10.18632/oncotarget.25317. eCollection 2018 May 18.

3.

Metabolic and Physiologic Imaging Biomarkers of the Tumor Microenvironment Predict Treatment Outcome with Radiation or a Hypoxia-Activated Prodrug in Mice.

Matsumoto S, Kishimoto S, Saito K, Takakusagi Y, Munasinghe JP, Devasahayam N, Hart CP, Gillies RJ, Mitchell JB, Krishna MC.

Cancer Res. 2018 Jul 15;78(14):3783-3792. doi: 10.1158/0008-5472.CAN-18-0491. Epub 2018 May 23.

PMID:
29792309
4.

Operando Atomic Force Microscopy Reveals Mechanics of Structural Water Driven Battery-to-Pseudocapacitor Transition.

Wang R, Mitchell JB, Gao Q, Tsai WY, Boyd S, Pharr M, Balke N, Augustyn V.

ACS Nano. 2018 May 21. doi: 10.1021/acsnano.8b02273. [Epub ahead of print]

PMID:
29767999
5.

Abemaciclib, a Selective CDK4/6 Inhibitor, Enhances the Radiosensitivity of Non-Small Cell Lung Cancer In Vitro and In Vivo.

Naz S, Sowers A, Choudhuri R, Wissler M, Gamson J, Mathias A, Cook JA, Mitchell JB.

Clin Cancer Res. 2018 May 1. doi: 10.1158/1078-0432.CCR-17-3575. [Epub ahead of print]

PMID:
29716919
6.

Wireless implantable coil with parametric amplification for in vivo electron paramagnetic resonance oximetric applications.

Enomoto A, Qian C, Devasahayam N, Kishimoto S, Oshima N, Blackman B, Swenson RE, Mitchell JB, Koretsky AP, Krishna MC.

Magn Reson Med. 2018 Mar 30. doi: 10.1002/mrm.27185. [Epub ahead of print]

PMID:
29603378
7.

Hyperpolarized [1-13C]-Pyruvate Magnetic Resonance Spectroscopic Imaging of Prostate Cancer In Vivo Predicts Efficacy of Targeting the Warburg Effect.

Scroggins BT, Matsuo M, White AO, Saito K, Munasinghe JP, Sourbier C, Yamamoto K, Diaz V, Takakusagi Y, Ichikawa K, Mitchell JB, Krishna MC, Citrin DE.

Clin Cancer Res. 2018 Jul 1;24(13):3137-3148. doi: 10.1158/1078-0432.CCR-17-1957. Epub 2018 Mar 29.

PMID:
29599412
8.

Cancer Incidence in C3H Mice Protected from Lethal Total-Body Radiation after Amifostine.

Cook JA, Naz S, Anver MR, Sowers AL, Fabre K, Krishna MC, Mitchell JB.

Radiat Res. 2018 May;189(5):490-496. doi: 10.1667/RR14987.1. Epub 2018 Mar 12.

9.

PD-1 blockade reverses adaptive immune resistance induced by high-dose hypofractionated but not low-dose daily fractionated radiation.

Morisada M, Clavijo PE, Moore E, Sun L, Chamberlin M, Van Waes C, Hodge JW, Mitchell JB, Friedman J, Allen CT.

Oncoimmunology. 2017 Nov 27;7(3):e1395996. doi: 10.1080/2162402X.2017.1395996. eCollection 2018.

PMID:
29399393
10.

Comparative studies with EPR and MRI on the in vivo tissue redox status estimation using redox-sensitive nitroxyl probes: influence of the choice of the region of interest.

Matsumoto KI, Mitchell JB, Krishna MC.

Free Radic Res. 2018 Feb;52(2):248-255. doi: 10.1080/10715762.2018.1427235. Epub 2018 Jan 31.

PMID:
29320888
11.

Molecular imaging of tumor photoimmunotherapy: Evidence of photosensitized tumor necrosis and hemodynamic changes.

Kishimoto S, Oshima N, Yamamoto K, Munasinghe J, Ardenkjaer-Larsen JH, Mitchell JB, Choyke PL, Krishna MC.

Free Radic Biol Med. 2018 Feb 20;116:1-10. doi: 10.1016/j.freeradbiomed.2017.12.034. Epub 2017 Dec 29.

PMID:
29289705
12.

Can human experts predict solubility better than computers?

Boobier S, Osbourn A, Mitchell JBO.

J Cheminform. 2017 Dec 13;9(1):63. doi: 10.1186/s13321-017-0250-y.

13.

Effect of body temperature on the pharmacokinetics of a triarylmethyl-type paramagnetic contrast agent used in EPR oximetry.

Matsumoto KI, Hyodo F, Mitchell JB, Krishna MC.

Magn Reson Med. 2018 Feb;79(2):1212-1218. doi: 10.1002/mrm.27008. Epub 2017 Nov 16.

PMID:
29143987
14.

Pulsed Electron Paramagnetic Resonance Imaging: Applications in the Studies of Tumor Physiology.

Kishimoto S, Matsumoto KI, Saito K, Enomoto A, Matsumoto S, Mitchell JB, Devasahayam N, Krishna MC.

Antioxid Redox Signal. 2018 May 20;28(15):1378-1393. doi: 10.1089/ars.2017.7391. Epub 2018 Jan 9.

PMID:
29130334
15.

Enzyme function and its evolution.

Mitchell JB.

Curr Opin Struct Biol. 2017 Dec;47:151-156. doi: 10.1016/j.sbi.2017.10.004. Epub 2017 Oct 27. Review.

PMID:
29107208
16.

Quantitative imaging of pO2 in orthotopic murine gliomas: hypoxia correlates with resistance to radiation.

Yasui H, Kawai T, Matsumoto S, Saito K, Devasahayam N, Mitchell JB, Camphausen K, Inanami O, Krishna MC.

Free Radic Res. 2017 Oct;51(9-10):861-871. doi: 10.1080/10715762.2017.1388506.

PMID:
29076398
17.

Mechanisms of Normal Tissue Injury From Irradiation.

Citrin DE, Mitchell JB.

Semin Radiat Oncol. 2017 Oct;27(4):316-324. doi: 10.1016/j.semradonc.2017.04.001. Review.

PMID:
28865514
18.

Radiotherapy Synergizes with the Hypoxia-Activated Prodrug Evofosfamide: In Vitro and In Vivo Studies.

Takakusagi Y, Kishimoto S, Naz S, Matsumoto S, Saito K, Hart CP, Mitchell JB, Krishna MC.

Antioxid Redox Signal. 2018 Jan 10;28(2):131-140. doi: 10.1089/ars.2017.7106. Epub 2017 Sep 8.

PMID:
28741367
19.

Rational drug design of antineoplastic agents using 3D-QSAR, cheminformatic, and virtual screening approaches.

Vucicevic J, Nikolic K, Mitchell JBO.

Curr Med Chem. 2017 Jul 12. doi: 10.2174/0929867324666170712115411. [Epub ahead of print]

PMID:
28707592
20.

Dose-dependent enhancement of T-lymphocyte priming and CTL lysis following ionizing radiation in an engineered model of oral cancer.

Morisada M, Moore EC, Hodge R, Friedman J, Cash HA, Hodge JW, Mitchell JB, Allen CT.

Oral Oncol. 2017 Aug;71:87-94. doi: 10.1016/j.oraloncology.2017.06.005. Epub 2017 Jun 10.

PMID:
28688697
21.

Effect of amifostine, a radiation-protecting drug, on oxygen concentration in tissue measured by EPR oximetry and imaging.

Ueno M, Matsumoto S, Matsumoto A, Manda S, Nakanishi I, Matsumoto KI, Mitchell JB, Krishna MC, Anzai K.

J Clin Biochem Nutr. 2017 May;60(3):151-155. doi: 10.3164/jcbn.15-130. Epub 2017 Mar 25.

22.

Dissociative Recombination of Acetone Fragments, Adducts, and Dimer Ions.

Al Shammari S, Almeida GC, Rocco MLM, Le Garrec JL, Mitchell JBA.

J Phys Chem A. 2017 Jun 1;121(21):4114-4122. doi: 10.1021/acs.jpca.7b00987. Epub 2017 May 18.

PMID:
28449576
23.

Effect of Tempol on the prevention of irradiation-induced mucositis in miniature pigs.

Hu L, Wang Y, Cotrim AP, Zhu Z, Gao R, Zheng C, Goldsmith CM, Jin L, Zhang C, Mitchell JB, Baum BJ, Wang S.

Oral Dis. 2017 Sep;23(6):801-808. doi: 10.1111/odi.12667. Epub 2017 Apr 27.

PMID:
28326646
24.

Oral administration of the nitroxide radical TEMPOL exhibits immunomodulatory and therapeutic properties in multiple sclerosis models.

Neil S, Huh J, Baronas V, Li X, McFarland HF, Cherukuri M, Mitchell JB, Quandt JA.

Brain Behav Immun. 2017 May;62:332-343. doi: 10.1016/j.bbi.2017.02.018. Epub 2017 Feb 24.

25.

Are the Sublimation Thermodynamics of Organic Molecules Predictable?

McDonagh JL, Palmer DS, Mourik TV, Mitchell JB.

J Chem Inf Model. 2016 Nov 28;56(11):2162-2179. Epub 2016 Nov 2.

PMID:
27749062
26.

Mammalian Target of Rapamycin Inhibition With Rapamycin Mitigates Radiation-Induced Pulmonary Fibrosis in a Murine Model.

Chung EJ, Sowers A, Thetford A, McKay-Corkum G, Chung SI, Mitchell JB, Citrin DE.

Int J Radiat Oncol Biol Phys. 2016 Nov 15;96(4):857-866. doi: 10.1016/j.ijrobp.2016.07.026. Epub 2016 Jul 28.

27.

Erratum: Predicting Melting Points of Organic Molecules: Applications to Aqueous Solubility Prediction Using the General Solubility Equation.

McDonagh JL, van Mourik T, Mitchell JB.

Mol Inform. 2016 Oct;35(10):538. doi: 10.1002/minf.201681041. No abstract available.

PMID:
27712042
28.

Ingestion of High Molecular Weight Carbohydrate Enhances Subsequent Repeated Maximal Power: A Randomized Controlled Trial.

Oliver JM, Almada AL, Van Eck LE, Shah M, Mitchell JB, Jones MT, Jagim AR, Rowlands DS.

PLoS One. 2016 Sep 16;11(9):e0163009. doi: 10.1371/journal.pone.0163009. eCollection 2016.

29.

Novel Form of Curcumin Improves Endothelial Function in Young, Healthy Individuals: A Double-Blind Placebo Controlled Study.

Oliver JM, Stoner L, Rowlands DS, Caldwell AR, Sanders E, Kreutzer A, Mitchell JB, Purpura M, Jäger R.

J Nutr Metab. 2016;2016:1089653. doi: 10.1155/2016/1089653. Epub 2016 Aug 17.

30.

A Random Forest Model for Predicting Allosteric and Functional Sites on Proteins.

Chen AS, Westwood NJ, Brear P, Rogers GW, Mavridis L, Mitchell JB.

Mol Inform. 2016 Apr;35(3-4):125-35. doi: 10.1002/minf.201500108. Epub 2016 Jan 21.

PMID:
27491922
31.

Predicting Melting Points of Organic Molecules: Applications to Aqueous Solubility Prediction Using the General Solubility Equation.

McDonagh JL, van Mourik T, Mitchell JB.

Mol Inform. 2015 Nov;34(11-12):715-24. doi: 10.1002/minf.201500052. Epub 2015 Jul 20. Erratum in: Mol Inform. 2016 Oct;35(10 ):538.

PMID:
27491032
32.

Greedy and Linear Ensembles of Machine Learning Methods Outperform Single Approaches for QSPR Regression Problems.

Kew W, Mitchell JB.

Mol Inform. 2015 Sep;34(9):634-47. doi: 10.1002/minf.201400122. Epub 2015 Mar 25.

PMID:
27490713
33.

SMAC Mimetic Birinapant plus Radiation Eradicates Human Head and Neck Cancers with Genomic Amplifications of Cell Death Genes FADD and BIRC2.

Eytan DF, Snow GE, Carlson S, Derakhshan A, Saleh A, Schiltz S, Cheng H, Mohan S, Cornelius S, Coupar J, Sowers AL, Hernandez L, Mitchell JB, Annunziata CM, Chen Z, Van Waes C.

Cancer Res. 2016 Sep 15;76(18):5442-5454. doi: 10.1158/0008-5472.CAN-15-3317. Epub 2016 Jul 28.

34.

Radiation-Induced Microvascular Injury as a Mechanism of Salivary Gland Hypofunction and Potential Target for Radioprotectors.

Mizrachi A, Cotrim AP, Katabi N, Mitchell JB, Verheij M, Haimovitz-Friedman A.

Radiat Res. 2016 Aug;186(2):189-95. doi: 10.1667/RR14431.1. Epub 2016 Jul 26.

35.

Drug Design for CNS Diseases: Polypharmacological Profiling of Compounds Using Cheminformatic, 3D-QSAR and Virtual Screening Methodologies.

Nikolic K, Mavridis L, Djikic T, Vucicevic J, Agbaba D, Yelekci K, Mitchell JB.

Front Neurosci. 2016 Jun 10;10:265. doi: 10.3389/fnins.2016.00265. eCollection 2016. Review.

36.

Preclinical Data on Efficacy of 10 Drug-Radiation Combinations: Evaluations, Concerns, and Recommendations.

Stone HB, Bernhard EJ, Coleman CN, Deye J, Capala J, Mitchell JB, Brown JM.

Transl Oncol. 2016 Feb;9(1):46-56. doi: 10.1016/j.tranon.2016.01.002. Review.

37.

Truncated Plasminogen Activator Inhibitor-1 Protein Protects From Pulmonary Fibrosis Mediated by Irradiation in a Murine Model.

Chung EJ, McKay-Corkum G, Chung S, White A, Scroggins BT, Mitchell JB, Mulligan-Kehoe MJ, Citrin D.

Int J Radiat Oncol Biol Phys. 2016 Apr 1;94(5):1163-72. doi: 10.1016/j.ijrobp.2015.11.044. Epub 2015 Dec 14.

38.

Mass Spectrometry-Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer.

Cook JA, Chandramouli GV, Anver MR, Sowers AL, Thetford A, Krausz KW, Gonzalez FJ, Mitchell JB, Patterson AD.

Cancer Res. 2016 Mar 15;76(6):1569-77. doi: 10.1158/0008-5472.CAN-15-2416. Epub 2016 Feb 15.

39.

Parent health literacy and adherence-related outcomes in children with epilepsy.

Paschal AM, Mitchell QP, Wilroy JD, Hawley SR, Mitchell JB.

Epilepsy Behav. 2016 Mar;56:73-82. doi: 10.1016/j.yebeh.2015.12.036. Epub 2016 Feb 3.

PMID:
26851644
40.

Why do Sequence Signatures Predict Enzyme Mechanism? Homology versus Chemistry.

Beattie KE, De Ferrari L, Mitchell JB.

Evol Bioinform Online. 2015 Dec 29;11:267-74. doi: 10.4137/EBO.S31482. eCollection 2015.

41.

Oxidation-Induced Surface Roughening of Aluminum Nanoparticles Formed in an Ablation Plume.

Förster GD, Girault M, Menneveux J, Lavisse L, Jouvard JM, Marco de Lucas Mdel C, Potin V, Ouf FX, Kerkar M, Le Garrec JL, Carvou E, Carles S, Rabilloud F, Calvo F, Yu J, Mitchell JB.

Phys Rev Lett. 2015 Dec 11;115(24):246101. doi: 10.1103/PhysRevLett.115.246101. Epub 2015 Dec 11.

PMID:
26705641
42.

Enzyme mechanism prediction: a template matching problem on InterPro signature subspaces.

Mussa HY, De Ferrari L, Mitchell JB.

BMC Res Notes. 2015 Dec 3;8:744. doi: 10.1186/s13104-015-1730-7.

43.

A note on utilising binary features as ligand descriptors.

Mussa HY, Mitchell JB, Glen RC.

J Cheminform. 2015 Dec 1;7:58. doi: 10.1186/s13321-015-0105-3. eCollection 2015.

44.

Adsorption studies of divalent, dinuclear coordination complexes as molecular spacers on SWCNTs.

Alston JR, Banks DJ, McNeill CX, Mitchell JB, Popov LD, Shcherbakov IN, Poler JC.

Phys Chem Chem Phys. 2015 Nov 28;17(44):29566-73. doi: 10.1039/c5cp05419b. Epub 2015 Oct 12.

PMID:
26457656
45.

The Parzen Window method: In terms of two vectors and one matrix.

Mussa HY, Mitchell JB, Afzal AM.

Pattern Recognit Lett. 2015 Oct 1;63:30-35.

46.

X-ray Photoelectron Spectroscopy of Isolated Nanoparticles.

Sublemontier O, Nicolas C, Aureau D, Patanen M, Kintz H, Liu X, Gaveau MA, Le Garrec JL, Robert E, Barreda FA, Etcheberry A, Reynaud C, Mitchell JB, Miron C.

J Phys Chem Lett. 2014 Oct 2;5(19):3399-403. doi: 10.1021/jz501532c. Epub 2014 Sep 19.

PMID:
26278452
47.

Temperature Measurement Inside Protective Headgear: Comparison With Core Temperatures and Indicators of Physiological Strain During Exercise in a Hot Environment.

Mitchell JB, Goldston KR, Adams AN, Crisp KM, Franklin BB, Kreutzer A, Montalvo DX, Turner MG, Phillips MD.

J Occup Environ Hyg. 2015;12(12):866-74. doi: 10.1080/15459624.2015.1072631.

PMID:
26259634
48.

Acute response to cluster sets in trained and untrained men.

Oliver JM, Kreutzer A, Jenke S, Phillips MD, Mitchell JB, Jones MT.

Eur J Appl Physiol. 2015 Nov;115(11):2383-93. doi: 10.1007/s00421-015-3216-7. Epub 2015 Jul 17.

PMID:
26183257
49.

Velocity Drives Greater Power Observed During Back Squat Using Cluster Sets.

Oliver JM, Kreutzer A, Jenke SC, Phillips MD, Mitchell JB, Jones MT.

J Strength Cond Res. 2016 Jan;30(1):235-43. doi: 10.1519/JSC.0000000000001023.

PMID:
26121432
50.

Verifying the fully "Laplacianised" posterior Naïve Bayesian approach and more.

Mussa HY, Marcus D, Mitchell JB, Glen RC.

J Cheminform. 2015 Jun 12;7:27. doi: 10.1186/s13321-015-0075-5. eCollection 2015.

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