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Items: 1 to 50 of 262

1.

PD-L1 expression heterogeneity in non-small cell lung cancer: evaluation of small biopsies reliability.

Munari E, Zamboni G, Marconi M, Sommaggio M, Brunelli M, Martignoni G, Netto GJ, Moretta F, Mingari MC, Salgarello M, Terzi A, Picece V, Pomari C, Lunardi G, Cavazza A, Rossi G, Moretta L, Bogina G.

Oncotarget. 2017 Oct 4;8(52):90123-90131. doi: 10.18632/oncotarget.21485. eCollection 2017 Oct 27.

2.

A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct αβ T cell receptors.

Sullivan LC, Walpole NG, Farenc C, Pietra G, Sum MJW, Clements CS, Lee EJ, Beddoe T, Falco M, Mingari MC, Moretta L, Gras S, Rossjohn J, Brooks AG.

J Biol Chem. 2017 Dec 22;292(51):21149-21158. doi: 10.1074/jbc.M117.807719. Epub 2017 Sep 25.

PMID:
28972140
3.

IL15 induces a potent antitumor activity in NK cells isolated from malignant pleural effusions and overcomes the inhibitory effect of pleural fluid.

Croxatto D, Martini S, Chiossone L, Scordamaglia F, Simonassi CF, Moretta L, Mingari MC, Vacca P.

Oncoimmunology. 2017 Feb 17;6(4):e1293210. doi: 10.1080/2162402X.2017.1293210. eCollection 2017.

4.

Inhibitory 2B4 contributes to NK cell education and immunological derangements in XLP1 patients.

Meazza R, Falco M, Marcenaro S, Loiacono F, Canevali P, Bellora F, Tuberosa C, Locatelli F, Micalizzi C, Moretta A, Mingari MC, Moretta L, Aricò M, Bottino C, Pende D.

Eur J Immunol. 2017 Jun;47(6):1051-1061. doi: 10.1002/eji.201646885. Epub 2017 May 5.

PMID:
28386908
5.

Markers and function of human NK cells in normal and pathological conditions.

Del Zotto G, Marcenaro E, Vacca P, Sivori S, Pende D, Della Chiesa M, Moretta F, Ingegnere T, Mingari MC, Moretta A, Moretta L.

Cytometry B Clin Cytom. 2017 Mar;92(2):100-114. doi: 10.1002/cyto.b.21508. Epub 2017 Feb 12. Review.

PMID:
28054442
6.

Human innate lymphoid cells.

Montaldo E, Vacca P, Vitale C, Moretta F, Locatelli F, Mingari MC, Moretta L.

Immunol Lett. 2016 Nov;179:2-8. doi: 10.1016/j.imlet.2016.01.007. Epub 2016 Feb 1. Review.

PMID:
26844414
7.

Cytokines can counteract the inhibitory effect of MEK-i on NK-cell function.

Manzini C, Venè R, Cossu I, Gualco M, Zupo S, Dono M, Spagnolo F, Queirolo P, Moretta L, Mingari MC, Pietra G.

Oncotarget. 2016 Sep 20;7(38):60858-60871. doi: 10.18632/oncotarget.11504.

8.

NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy?

Cantoni C, Huergo-Zapico L, Parodi M, Pedrazzi M, Mingari MC, Moretta A, Sparatore B, Gonzalez S, Olive D, Bottino C, Castriconi R, Vitale M.

J Immunol Res. 2016;2016:4684268. doi: 10.1155/2016/4684268. Epub 2016 May 12. Review.

9.

NK Cells and Other Innate Lymphoid Cells in Hematopoietic Stem Cell Transplantation.

Vacca P, Montaldo E, Croxatto D, Moretta F, Bertaina A, Vitale C, Locatelli F, Mingari MC, Moretta L.

Front Immunol. 2016 May 18;7:188. doi: 10.3389/fimmu.2016.00188. eCollection 2016. Review.

10.

Human NK cells: From surface receptors to clinical applications.

Moretta L, Pietra G, Vacca P, Pende D, Moretta F, Bertaina A, Mingari MC, Locatelli F, Moretta A.

Immunol Lett. 2016 Oct;178:15-9. doi: 10.1016/j.imlet.2016.05.007. Epub 2016 May 13.

PMID:
27185471
11.

Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition.

Saunders PM, Pymm P, Pietra G, Hughes VA, Hitchen C, O'Connor GM, Loiacono F, Widjaja J, Price DA, Falco M, Mingari MC, Moretta L, McVicar DW, Rossjohn J, Brooks AG, Vivian JP.

J Exp Med. 2016 May 2;213(5):791-807. doi: 10.1084/jem.20152023. Epub 2016 Apr 4.

12.

Group 3 innate lymphoid cells regulate neutrophil migration and function in human decidua.

Croxatto D, Micheletti A, Montaldo E, Orecchia P, Loiacono F, Canegallo F, Calzetti F, Fulcheri E, Munari E, Zamò A, Venturini PL, Moretta L, Cassatella MA, Mingari MC, Vacca P.

Mucosal Immunol. 2016 Nov;9(6):1372-1383. doi: 10.1038/mi.2016.10. Epub 2016 Feb 24.

PMID:
26906405
13.

The generation of human innate lymphoid cells is influenced by the source of hematopoietic stem cells and by the use of G-CSF.

Moretta F, Petronelli F, Lucarelli B, Pitisci A, Bertaina A, Locatelli F, Mingari MC, Moretta L, Montaldo E.

Eur J Immunol. 2016 May;46(5):1271-8. doi: 10.1002/eji.201546079. Epub 2016 Feb 19.

14.

Natural Killer (NK)/melanoma cell interaction induces NK-mediated release of chemotactic High Mobility Group Box-1 (HMGB1) capable of amplifying NK cell recruitment.

Parodi M, Pedrazzi M, Cantoni C, Averna M, Patrone M, Cavaletto M, Spertino S, Pende D, Balsamo M, Pietra G, Sivori S, Carlomagno S, Mingari MC, Moretta L, Sparatore B, Vitale M.

Oncoimmunology. 2015 May 29;4(12):e1052353. eCollection 2015 Dec.

15.

Targeting Syndecan-1, a molecule implicated in the process of vasculogenic mimicry, enhances the therapeutic efficacy of the L19-IL2 immunocytokine in human melanoma xenografts.

Orecchia P, Conte R, Balza E, Pietra G, Mingari MC, Carnemolla B.

Oncotarget. 2015 Nov 10;6(35):37426-42. doi: 10.18632/oncotarget.6055.

16.

NCR(+)ILC3 concentrate in human lung cancer and associate with intratumoral lymphoid structures.

Carrega P, Loiacono F, Di Carlo E, Scaramuccia A, Mora M, Conte R, Benelli R, Spaggiari GM, Cantoni C, Campana S, Bonaccorsi I, Morandi B, Truini M, Mingari MC, Moretta L, Ferlazzo G.

Nat Commun. 2015 Sep 23;6:8280. doi: 10.1038/ncomms9280.

PMID:
26395069
17.

A non-canonical adenosinergic pathway led by CD38 in human melanoma cells induces suppression of T cell proliferation.

Morandi F, Morandi B, Horenstein AL, Chillemi A, Quarona V, Zaccarello G, Carrega P, Ferlazzo G, Mingari MC, Moretta L, Pistoia V, Malavasi F.

Oncotarget. 2015 Sep 22;6(28):25602-18. doi: 10.18632/oncotarget.4693.

18.

Role of NK cells in immunotherapy and virotherapy of solid tumors.

Cantoni C, Grauwet K, Pietra G, Parodi M, Mingari MC, Maria AD, Favoreel H, Vitale M.

Immunotherapy. 2015;7(8):861-82. doi: 10.2217/imt.15.53. Epub 2015 Aug 28. Review.

PMID:
26314197
19.

Human natural killer cells: news in the therapy of solid tumors and high-risk leukemias.

Pietra G, Vitale C, Pende D, Bertaina A, Moretta F, Falco M, Vacca P, Montaldo E, Cantoni C, Mingari MC, Moretta A, Locatelli F, Moretta L.

Cancer Immunol Immunother. 2016 Apr;65(4):465-76. doi: 10.1007/s00262-015-1744-y. Epub 2015 Aug 20. Review.

PMID:
26289090
20.

MSC and innate immune cell interactions: A lesson from human decidua.

Vacca P, Montaldo E, Vitale C, Croxatto D, Moretta L, Mingari MC.

Immunol Lett. 2015 Dec;168(2):170-4. doi: 10.1016/j.imlet.2015.05.006. Epub 2015 May 15. Review.

PMID:
25986011
21.

IL-1β inhibits ILC3 while favoring NK-cell maturation of umbilical cord blood CD34(+) precursors.

Ambrosini P, Loiacono F, Conte R, Moretta L, Vitale C, Mingari MC.

Eur J Immunol. 2015 Jul;45(7):2061-71. doi: 10.1002/eji.201445326. Epub 2015 May 12. Erratum in: Eur J Immunol. 2015 Aug;45(8):2420.

22.

Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokines.

Caccamo N, Pietra G, Sullivan LC, Brooks AG, Prezzemolo T, La Manna MP, Di Liberto D, Joosten SA, van Meijgaarden KE, Di Carlo P, Titone L, Moretta L, Mingari MC, Ottenhoff TH, Dieli F.

Eur J Immunol. 2015 Apr;45(4):1069-81. doi: 10.1002/eji.201445193. Epub 2015 Feb 17.

23.

Unique Eomes(+) NK Cell Subsets Are Present in Uterus and Decidua During Early Pregnancy.

Montaldo E, Vacca P, Chiossone L, Croxatto D, Loiacono F, Martini S, Ferrero S, Walzer T, Moretta L, Mingari MC.

Front Immunol. 2016 Jan 7;6:646. doi: 10.3389/fimmu.2015.00646. eCollection 2015.

24.

Human RORγt(+)CD34(+) cells are lineage-specified progenitors of group 3 RORγt(+) innate lymphoid cells.

Montaldo E, Teixeira-Alves LG, Glatzer T, Durek P, Stervbo U, Hamann W, Babic M, Paclik D, Stölzel K, Gröne J, Lozza L, Juelke K, Matzmohr N, Loiacono F, Petronelli F, Huntington ND, Moretta L, Mingari MC, Romagnani C.

Immunity. 2014 Dec 18;41(6):988-1000. doi: 10.1016/j.immuni.2014.11.010. Epub 2014 Nov 28.

25.

IL-1β-releasing human acute myeloid leukemia blasts modulate natural killer cell differentiation from CD34+ precursors.

Vitale C, Ambrosini P, Montaldo E, Ballerini F, Moretta L, Mingari MC.

Haematologica. 2015 Feb;100(2):e42-5. doi: 10.3324/haematol.2014.110494. Epub 2014 Oct 24. No abstract available.

26.

Human natural killer cells: origin, receptors, function, and clinical applications.

Moretta L, Montaldo E, Vacca P, Del Zotto G, Moretta F, Merli P, Locatelli F, Mingari MC.

Int Arch Allergy Immunol. 2014;164(4):253-64. doi: 10.1159/000365632. Epub 2014 Aug 26. Review.

PMID:
25323661
27.

Identification of diverse innate lymphoid cells in human decidua.

Vacca P, Montaldo E, Croxatto D, Loiacono F, Canegallo F, Venturini PL, Moretta L, Mingari MC.

Mucosal Immunol. 2015 Mar;8(2):254-64. doi: 10.1038/mi.2014.63. Epub 2014 Jul 23.

PMID:
25052762
28.

Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis.

Meazza R, Tuberosa C, Cetica V, Falco M, Parolini S, Grieve S, Griffiths GM, Sieni E, Marcenaro S, Micalizzi C, Montin D, Fagioli F, Moretta A, Mingari MC, Moretta L, Notarangelo LD, Bottino C, Aricò M, Pende D.

J Allergy Clin Immunol. 2014 Dec;134(6):1381-1387.e7. doi: 10.1016/j.jaci.2014.04.043. Epub 2014 Jun 27.

PMID:
24985396
29.

Effect of tumor cells and tumor microenvironment on NK-cell function.

Vitale M, Cantoni C, Pietra G, Mingari MC, Moretta L.

Eur J Immunol. 2014 Jun;44(6):1582-92. doi: 10.1002/eji.201344272. Review.

30.

CD56(bright)perforin(low) noncytotoxic human NK cells are abundant in both healthy and neoplastic solid tissues and recirculate to secondary lymphoid organs via afferent lymph.

Carrega P, Bonaccorsi I, Di Carlo E, Morandi B, Paul P, Rizzello V, Cipollone G, Navarra G, Mingari MC, Moretta L, Ferlazzo G.

J Immunol. 2014 Apr 15;192(8):3805-15. doi: 10.4049/jimmunol.1301889. Epub 2014 Mar 19.

31.

Human NK cells: from surface receptors to the therapy of leukemias and solid tumors.

Moretta L, Pietra G, Montaldo E, Vacca P, Pende D, Falco M, Del Zotto G, Locatelli F, Moretta A, Mingari MC.

Front Immunol. 2014 Mar 7;5:87. doi: 10.3389/fimmu.2014.00087. eCollection 2014. Review.

32.

Stromal cells from human decidua exert a strong inhibitory effect on NK cell function and dendritic cell differentiation.

Croxatto D, Vacca P, Canegallo F, Conte R, Venturini PL, Moretta L, Mingari MC.

PLoS One. 2014 Feb 20;9(2):e89006. doi: 10.1371/journal.pone.0089006. eCollection 2014.

33.

Chronic lymphocytic leukemia nurse-like cells express hepatocyte growth factor receptor (c-MET) and indoleamine 2,3-dioxygenase and display features of immunosuppressive type 2 skewed macrophages.

Giannoni P, Pietra G, Travaini G, Quarto R, Shyti G, Benelli R, Ottaggio L, Mingari MC, Zupo S, Cutrona G, Pierri I, Balleari E, Pattarozzi A, Calvaruso M, Tripodo C, Ferrarini M, de Totero D.

Haematologica. 2014 Jun;99(6):1078-87. doi: 10.3324/haematol.2013.091405. Epub 2014 Feb 21.

34.

Development of human natural killer cells and other innate lymphoid cells.

Montaldo E, Vacca P, Moretta L, Mingari MC.

Semin Immunol. 2014 Apr;26(2):107-13. doi: 10.1016/j.smim.2014.01.006. Epub 2014 Feb 18. Review.

PMID:
24559836
35.

XLP1 inhibitory effect by 2B4 does not affect DNAM-1 and NKG2D activating pathways in NK cells.

Meazza R, Tuberosa C, Cetica V, Falco M, Loiacono F, Parolini S, Micalizzi C, Moretta A, Mingari MC, Moretta L, Bottino C, Aricò M, Pende D.

Eur J Immunol. 2014 May;44(5):1526-34. doi: 10.1002/eji.201344312. Epub 2014 Feb 27.

36.

HLA-G is a component of the chronic lymphocytic leukemia escape repertoire to generate immune suppression: impact of the HLA-G 14 base pair (rs66554220) polymorphism.

Rizzo R, Audrito V, Vacca P, Rossi D, Brusa D, Stignani M, Bortolotti D, D'Arena G, Coscia M, Laurenti L, Forconi F, Gaidano G, Mingari MC, Moretta L, Malavasi F, Deaglio S.

Haematologica. 2014 May;99(5):888-96. doi: 10.3324/haematol.2013.095281. Epub 2013 Dec 20.

37.

Membrane transfer from tumor cells overcomes deficient phagocytic ability of plasmacytoid dendritic cells for the acquisition and presentation of tumor antigens.

Bonaccorsi I, Morandi B, Antsiferova O, Costa G, Oliveri D, Conte R, Pezzino G, Vermiglio G, Anastasi GP, Navarra G, Münz C, Di Carlo E, Mingari MC, Ferlazzo G.

J Immunol. 2014 Jan 15;192(2):824-32. doi: 10.4049/jimmunol.1301039. Epub 2013 Dec 11.

38.

In vivo generation of decidual natural killer cells from resident hematopoietic progenitors.

Chiossone L, Vacca P, Orecchia P, Croxatto D, Damonte P, Astigiano S, Barbieri O, Bottino C, Moretta L, Mingari MC.

Haematologica. 2014 Mar;99(3):448-57. doi: 10.3324/haematol.2013.091421. Epub 2013 Oct 31.

39.

Characterization of human afferent lymph dendritic cells from seroma fluids.

Morandi B, Bonaccorsi I, Mesiti M, Conte R, Carrega P, Costa G, Iemmo R, Martini S, Ferrone S, Cantoni C, Mingari MC, Moretta L, Ferlazzo G.

J Immunol. 2013 Nov 1;191(9):4858-66. doi: 10.4049/jimmunol.1300760. Epub 2013 Sep 27.

40.

Understanding human NK cell differentiation: clues for improving the haploidentical hematopoietic stem cell transplantation.

Montaldo E, Vacca P, Moretta L, Mingari MC.

Immunol Lett. 2013 Sep-Oct;155(1-2):2-5. doi: 10.1016/j.imlet.2013.09.022. Epub 2013 Sep 26. Review. Erratum in: Immunol Lett. 2014 May-Jun;159(1-2):80.

PMID:
24076313
41.

Hypoxia downregulates the expression of activating receptors involved in NK-cell-mediated target cell killing without affecting ADCC.

Balsamo M, Manzini C, Pietra G, Raggi F, Blengio F, Mingari MC, Varesio L, Moretta L, Bosco MC, Vitale M.

Eur J Immunol. 2013 Oct;43(10):2756-64. doi: 10.1002/eji.201343448. Epub 2013 Aug 5.

42.

NK cells from malignant pleural effusions are potent antitumor effectors: A clue for adoptive immunotherapy?

Vacca P, Martini S, Mingari MC, Moretta L.

Oncoimmunology. 2013 Apr 1;2(4):e23638.

43.

Human NK cell receptors/markers: a tool to analyze NK cell development, subsets and function.

Montaldo E, Del Zotto G, Della Chiesa M, Mingari MC, Moretta A, De Maria A, Moretta L.

Cytometry A. 2013 Aug;83(8):702-13. doi: 10.1002/cyto.a.22302. Epub 2013 May 6. Review.

44.

The engagement of CTLA-4 on primary melanoma cell lines induces antibody-dependent cellular cytotoxicity and TNF-α production.

Laurent S, Queirolo P, Boero S, Salvi S, Piccioli P, Boccardo S, Minghelli S, Morabito A, Fontana V, Pietra G, Carrega P, Ferrari N, Tosetti F, Chang LJ, Mingari MC, Ferlazzo G, Poggi A, Pistillo MP.

J Transl Med. 2013 May 1;11:108. doi: 10.1186/1479-5876-11-108.

45.

Natural killer cells in human pregnancy.

Vacca P, Mingari MC, Moretta L.

J Reprod Immunol. 2013 Mar;97(1):14-9. doi: 10.1016/j.jri.2012.10.008. Review.

PMID:
23432867
46.

Cellular and molecular basis of haploidentical hematopoietic stem cell transplantation in the successful treatment of high-risk leukemias: role of alloreactive NK cells.

Locatelli F, Pende D, Mingari MC, Bertaina A, Falco M, Moretta A, Moretta L.

Front Immunol. 2013 Feb 1;4:15. doi: 10.3389/fimmu.2013.00015. eCollection 2013.

47.

A novel human anti-syndecan-1 antibody inhibits vascular maturation and tumour growth in melanoma.

Orecchia P, Conte R, Balza E, Petretto A, Mauri P, Mingari MC, Carnemolla B.

Eur J Cancer. 2013 May;49(8):2022-33. doi: 10.1016/j.ejca.2012.12.019. Epub 2013 Jan 24.

PMID:
23352437
48.

Polymorphism in human cytomegalovirus UL40 impacts on recognition of human leukocyte antigen-E (HLA-E) by natural killer cells.

Heatley SL, Pietra G, Lin J, Widjaja JM, Harpur CM, Lester S, Rossjohn J, Szer J, Schwarer A, Bradstock K, Bardy PG, Mingari MC, Moretta L, Sullivan LC, Brooks AG.

J Biol Chem. 2013 Mar 22;288(12):8679-90. doi: 10.1074/jbc.M112.409672. Epub 2013 Jan 18.

49.

Melanoma immunoediting by NK cells.

Balsamo M, Pietra G, Vermi W, Moretta L, Mingari MC, Vitale M.

Oncoimmunology. 2012 Dec 1;1(9):1607-1609.

50.

NK cells from malignant pleural effusions are not anergic but produce cytokines and display strong antitumor activity on short-term IL-2 activation.

Vacca P, Martini S, Garelli V, Passalacqua G, Moretta L, Mingari MC.

Eur J Immunol. 2013 Feb;43(2):550-61. doi: 10.1002/eji.201242783. Epub 2013 Jan 15.

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