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Items: 20


Mechanistic Investigations of Diarrhea Toxicity Induced by anti-HER2/3 Combination Therapy.

Moisan A, Michielin F, Jacob W, Kronenberg S, Wilson S, Avignon B, Gérard R, Benmansour F, McIntyre C, Meneses-Lorente G, Hasmann M, Schneeweiss A, Weisser M, Adessi C.

Mol Cancer Ther. 2018 Apr 13. pii: molcanther.1268.2017. doi: 10.1158/1535-7163.MCT-17-1268. [Epub ahead of print]


Phase Ib study evaluating safety and clinical activity of the anti-HER3 antibody lumretuzumab combined with the anti-HER2 antibody pertuzumab and paclitaxel in HER3-positive, HER2-low metastatic breast cancer.

Schneeweiss A, Park-Simon TW, Albanell J, Lassen U, Cortés J, Dieras V, May M, Schindler C, Marmé F, Cejalvo JM, Martinez-Garcia M, Gonzalez I, Lopez-Martin J, Welt A, Levy C, Joly F, Michielin F, Jacob W, Adessi C, Moisan A, Meneses-Lorente G, Racek T, James I, Ceppi M, Hasmann M, Weisser M, Cervantes A.

Invest New Drugs. 2018 Jan 19. doi: 10.1007/s10637-018-0562-4. [Epub ahead of print]


Phase Ib Study of Lumretuzumab Plus Cetuximab or Erlotinib in Solid Tumor Patients and Evaluation of HER3 and Heregulin as Potential Biomarkers of Clinical Activity.

Meulendijks D, Jacob W, Voest EE, Mau-Sorensen M, Martinez-Garcia M, Taus A, Fleitas T, Cervantes A, Lolkema MP, Langenberg MHG, De Jonge MJ, Sleijfer S, Han JY, Calles A, Felip E, Kim SW, Schellens JHM, Wilson S, Thomas M, Ceppi M, Meneses-Lorente G, James I, Vega-Harring S, Dua R, Nguyen M, Steiner L, Adessi C, Michielin F, Bossenmaier B, Weisser M, Lassen UN.

Clin Cancer Res. 2017 Sep 15;23(18):5406-5415. doi: 10.1158/1078-0432.CCR-17-0812. Epub 2017 Jun 9.


High-efficiency cellular reprogramming with microfluidics.

Luni C, Giulitti S, Serena E, Ferrari L, Zambon A, Gagliano O, Giobbe GG, Michielin F, Knöbel S, Bosio A, Elvassore N.

Nat Methods. 2016 May;13(5):446-52. doi: 10.1038/nmeth.3832. Epub 2016 Apr 18.


Phase I clinical study of RG7356, an anti-CD44 humanized antibody, in patients with acute myeloid leukemia.

Vey N, Delaunay J, Martinelli G, Fiedler W, Raffoux E, Prebet T, Gomez-Roca C, Papayannidis C, Kebenko M, Paschka P, Christen R, Guarin E, Bröske AM, Baehner M, Brewster M, Walz AC, Michielin F, Runza V, Meresse V, Recher C.

Oncotarget. 2016 May 31;7(22):32532-42. doi: 10.18632/oncotarget.8687.


First-in-Human Phase I Study of Lumretuzumab, a Glycoengineered Humanized Anti-HER3 Monoclonal Antibody, in Patients with Metastatic or Advanced HER3-Positive Solid Tumors.

Meulendijks D, Jacob W, Martinez-Garcia M, Taus A, Lolkema MP, Voest EE, Langenberg MH, Fleitas Kanonnikoff T, Cervantes A, De Jonge MJ, Sleijfer S, Soerensen MM, Thomas M, Ceppi M, Meneses-Lorente G, James I, Adessi C, Michielin F, Abiraj K, Bossenmaier B, Schellens JH, Weisser M, Lassen UN.

Clin Cancer Res. 2016 Feb 15;22(4):877-85. doi: 10.1158/1078-0432.CCR-15-1683. Epub 2015 Oct 13.


Functional differentiation of human pluripotent stem cells on a chip.

Giobbe GG, Michielin F, Luni C, Giulitti S, Martewicz S, Dupont S, Floreani A, Elvassore N.

Nat Methods. 2015 Jul;12(7):637-40. doi: 10.1038/nmeth.3411. Epub 2015 Jun 1.


A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors.

Aragona M, Panciera T, Manfrin A, Giulitti S, Michielin F, Elvassore N, Dupont S, Piccolo S.

Cell. 2013 Aug 29;154(5):1047-1059. doi: 10.1016/j.cell.2013.07.042. Epub 2013 Aug 15.


Stochastic model-assisted development of efficient low-dose viral transduction in microfluidics.

Luni C, Michielin F, Barzon L, Calabrò V, Elvassore N.

Biophys J. 2013 Feb 19;104(4):934-42. doi: 10.1016/j.bpj.2012.12.049.


Reversible alteration of calcium dynamics in cardiomyocytes during acute hypoxia transient in a microfluidic platform.

Martewicz S, Michielin F, Serena E, Zambon A, Mongillo M, Elvassore N.

Integr Biol (Camb). 2012 Feb;4(2):153-64. doi: 10.1039/c1ib00087j. Epub 2011 Dec 13.


GSK1614343, a novel ghrelin receptor antagonist, produces an unexpected increase of food intake and body weight in rodents and dogs.

Costantini VJ, Vicentini E, Sabbatini FM, Valerio E, Lepore S, Tessari M, Sartori M, Michielin F, Melotto S, Bifone A, Pich EM, Corsi M.

Neuroendocrinology. 2011;94(2):158-68. doi: 10.1159/000328968. Epub 2011 Jul 22. Erratum in: Neuroendocrinology. 2012;95(3):247. Bifone, Angelo [added].


rKv1.2 overexpression in the central medial thalamic area decreases caffeine-induced arousal.

Cazzin C, Piccoli L, Massagrande M, Garbati N, Michielin F, Knaus HG, Ring CJ, Morrison AD, Merlo-Pich E, Rovo Z, Astori S, Lüthi A, Corti C, Corsi M.

Genes Brain Behav. 2011 Nov;10(8):817-27. doi: 10.1111/j.1601-183X.2011.00719.x. Epub 2011 Aug 7.


Slow dissociation of partial agonists from the D₂ receptor is linked to reduced prolactin release.

Carboni L, Negri M, Michielin F, Bertani S, Fratte SD, Oliosi B, Cavanni P.

Int J Neuropsychopharmacol. 2012 Jun;15(5):645-56. doi: 10.1017/S1461145711000824. Epub 2011 Jun 9.


Effect of the p38 MAPK inhibitor SB-239063 on Lipopolysaccharide-induced psychomotor retardation and peripheral biomarker alterations in rats.

Bison S, Razzoli M, Arban R, Michielin F, Bertani S, Carboni L.

Eur J Pharmacol. 2011 Jul 1;661(1-3):49-56. doi: 10.1016/j.ejphar.2011.04.020. Epub 2011 Apr 27.


Altered levels of glutamatergic receptors and Na+/K+ ATPase-α1 in the prefrontal cortex of subjects with schizophrenia.

Corti C, Xuereb JH, Crepaldi L, Corsi M, Michielin F, Ferraguti F.

Schizophr Res. 2011 May;128(1-3):7-14. doi: 10.1016/j.schres.2011.01.021. Epub 2011 Feb 24.


Macrolide antibiotics broadly and distinctively inhibit cytokine and chemokine production by COPD sputum cells in vitro.

Marjanović N, Bosnar M, Michielin F, Willé DR, Anić-Milić T, Culić O, Popović-Grle S, Bogdan M, Parnham MJ, Eraković Haber V.

Pharmacol Res. 2011 May;63(5):389-97. doi: 10.1016/j.phrs.2011.02.001. Epub 2011 Feb 17.


Circadian profile of peripheral hormone levels in Sprague-Dawley rats and in common marmosets (Callithrix jacchus).

Bertani S, Carboni L, Criado A, Michielin F, Mangiarini L, Vicentini E.

In Vivo. 2010 Nov-Dec;24(6):827-36.


Increased phasic activity of VTA dopamine neurons in mice 3 weeks after repeated social defeat.

Razzoli M, Andreoli M, Michielin F, Quarta D, Sokal DM.

Behav Brain Res. 2011 Mar 17;218(1):253-7. doi: 10.1016/j.bbr.2010.11.050. Epub 2010 Dec 1.


Strain-specific outcomes of repeated social defeat and chronic fluoxetine treatment in the mouse.

Razzoli M, Carboni L, Andreoli M, Michielin F, Ballottari A, Arban R.

Pharmacol Biochem Behav. 2011 Jan;97(3):566-76. doi: 10.1016/j.pbb.2010.09.010. Epub 2010 Sep 21.


[Epidemiology and prevention of rheumatic fever in Rio Grande do Sul].

Michielin F, Pretto AA, Prataviera JC, Holz JL, Paternoster R, Catalunha M, Michielin Filho F, Michielin JH.

Arq Bras Cardiol. 1994 Nov;63(5):441-2. Portuguese. No abstract available.


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