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Contaminants of Emerging Concern in Wastewaters in Barbados, West Indies.

Edwards QA, Sultana T, Kulikov SM, Garner-O'Neale LD, Yargeau V, Metcalfe CD.

Bull Environ Contam Toxicol. 2018 May 2. doi: 10.1007/s00128-018-2346-0. [Epub ahead of print]


Using conversation analytic methods to assess fidelity to a talk-based healthcare intervention for frequently attending patients.

Barnes RK, Jepson M, Thomas C, Jackson S, Metcalfe C, Kessler D, Cramer H.

Soc Sci Med. 2018 Jun;206:38-50. doi: 10.1016/j.socscimed.2018.04.008. Epub 2018 Apr 11.


Neonicotinoid pesticides in drinking water in agricultural regions of southern Ontario, Canada.

Sultana T, Murray C, Kleywegt S, Metcalfe CD.

Chemosphere. 2018 Jul;202:506-513. doi: 10.1016/j.chemosphere.2018.02.108. Epub 2018 Mar 21.


Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality: The CAP Randomized Clinical Trial.

Martin RM, Donovan JL, Turner EL, Metcalfe C, Young GJ, Walsh EI, Lane JA, Noble S, Oliver SE, Evans S, Sterne JAC, Holding P, Ben-Shlomo Y, Brindle P, Williams NJ, Hill EM, Ng SY, Toole J, Tazewell MK, Hughes LJ, Davies CF, Thorn JC, Down E, Davey Smith G, Neal DE, Hamdy FC; CAP Trial Group.

JAMA. 2018 Mar 6;319(9):883-895. doi: 10.1001/jama.2018.0154.


Attempted suicide in Sri Lanka - An epidemiological study of household and community factors.

Knipe DW, Gunnell D, Pearson M, Jayamanne S, Pieris R, Priyadarshana C, Weerasinghe M, Hawton K, Konradsen F, Eddleston M, Metcalfe C.

J Affect Disord. 2018 May;232:177-184. doi: 10.1016/j.jad.2018.01.028. Epub 2018 Feb 5.


Comparison of patient (POEM), observer (EASI, SASSAD, TIS) and corneometry measures of emollient effectiveness in children with eczema: findings from the COMET feasibility Trial.

Ridd MJ, Gaunt DM, Guy RH, Redmond NM, Garfield K, Hollinghurst S, Ball N, Shaw L, Purdy S, Metcalfe C.

Br J Dermatol. 2018 Feb 24. doi: 10.1111/bjd.16475. [Epub ahead of print]


Investigating the effectiveness and cost-effectiveness of FITNET-NHS (Fatigue In Teenagers on the interNET in the NHS) compared to Activity Management to treat paediatric chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME): protocol for a randomised controlled trial.

Baos S, Brigden A, Anderson E, Hollingworth W, Price S, Mills N, Beasant L, Gaunt D, Garfield K, Metcalfe C, Parslow R, Downing H, Kessler D, Macleod J, Stallard P, Knoop H, Van de Putte E, Nijhof S, Bleijenberg G, Crawley E.

Trials. 2018 Feb 22;19(1):136. doi: 10.1186/s13063-018-2500-3.


Developing new age-specific prostate-specific antigen thresholds for testing for prostate cancer.

Gilbert R, Tilling K, Martin RM, Lane JA, Davis M, Hamdy FC, Neal DE, Donovan JL, Metcalfe C.

Cancer Causes Control. 2018 Mar;29(3):383-388. doi: 10.1007/s10552-018-1014-3. Epub 2018 Feb 16.


Development of a framework to improve the process of recruitment to randomised controlled trials (RCTs): the SEAR (Screened, Eligible, Approached, Randomised) framework.

Wilson C, Rooshenas L, Paramasivan S, Elliott D, Jepson M, Strong S, Birtle A, Beard DJ, Halliday A, Hamdy FC, Lewis R, Metcalfe C, Rogers CA, Stein RC, Blazeby JM, Donovan JL.

Trials. 2018 Jan 19;19(1):50. doi: 10.1186/s13063-017-2413-6.


A prospective cohort and extended comprehensive-cohort design provided insights about the generalizability of a pragmatic trial: the ProtecT prostate cancer trial.

Donovan JL, Young GJ, Walsh EI, Metcalfe C, Lane JA, Martin RM, Tazewell MK, Davis M, Peters TJ, Turner EL, Mills N, Khazragui H, Khera TK, Neal DE, Hamdy FC; ProtecT Study Group.

J Clin Epidemiol. 2018 Apr;96:35-46. doi: 10.1016/j.jclinepi.2017.12.019. Epub 2017 Dec 27.


Biological Responses in Brook Trout (Salvelinus fontinalis) Caged Downstream from Municipal Wastewater Treatment Plants in the Credit River, ON, Canada.

McGovarin S, Sultana T, Metcalfe C.

Bull Environ Contam Toxicol. 2018 Jan;100(1):106-111. doi: 10.1007/s00128-017-2242-z. Epub 2017 Dec 11.


Action 3:30R: protocol for a cluster randomised feasibility study of a revised teaching assistant-led extracurricular physical activity intervention for 8- to 10-year-olds.

Tibbitts B, Porter A, Sebire SJ, Metcalfe C, Bird E, Powell J, Jago R.

Pilot Feasibility Stud. 2017 Dec 6;3:69. doi: 10.1186/s40814-017-0213-0. eCollection 2017.


Protocol for a feasibility study and randomised pilot trial of a low-intensity psychological intervention for depression in adults with autism: the Autism Depression Trial (ADEPT).

Russell A, Cooper K, Barton S, Ensum I, Gaunt D, Horwood J, Ingham B, Kessler D, Metcalfe C, Parr J, Rai D, Wiles N.

BMJ Open. 2017 Dec 3;7(12):e019545. doi: 10.1136/bmjopen-2017-019545.


Effect of imidacloprid on the survival of Xenopus tadpoles challenged with wild type frog virus 3.

Hrynyk MA, Brunetti C, Kerr L, Metcalfe CD.

Aquat Toxicol. 2018 Jan;194:152-158. doi: 10.1016/j.aquatox.2017.11.005. Epub 2017 Nov 12.


Nest-defense behaviors in fathead minnows after lifecycle exposure to the antidepressant venlafaxine.

Parrott JL, Metcalfe CD.

Environ Pollut. 2018 Mar;234:223-230. doi: 10.1016/j.envpol.2017.11.049. Epub 2017 Nov 24.


Contaminants of emerging concern in surface waters in Barbados, West Indies.

Edwards QA, Kulikov SM, Garner-O'Neale LD, Metcalfe CD, Sultana T.

Environ Monit Assess. 2017 Nov 14;189(12):636. doi: 10.1007/s10661-017-6341-4.


Cross-sectional study evaluating data quality of the National Cancer Registration and Analysis Service (NCRAS) prostate cancer registry data using the Cluster randomised trial of PSA testing for Prostate cancer (CAP).

Merriel SWD, Turner EL, Walsh E, Young GJ, Metcalfe C, Hounsome L, Tudge I, Donovan J, Hamdy F, Neal D, Martin RM.

BMJ Open. 2017 Nov 14;7(11):e015994. doi: 10.1136/bmjopen-2017-015994.


Prostate-specific antigen (PSA) testing of men in UK general practice: a 10-year longitudinal cohort study.

Young GJ, Harrison S, Turner EL, Walsh EI, Oliver SE, Ben-Shlomo Y, Evans S, Lane JA, Neal DE, Hamdy FC, Donovan JL, Martin RM, Metcalfe C.

BMJ Open. 2017 Oct 30;7(10):e017729. doi: 10.1136/bmjopen-2017-017729.


HOPE: Help fOr People with money, employment, benefit or housing problems: study protocol for a randomised controlled trial.

Barnes MC, Haase AM, Bard AM, Donovan JL, Davies R, Dursley S, Potokar J, Kapur N, Hawton K, O'Connor RC, Hollingworth W, Metcalfe C, Gunnell D.

Pilot Feasibility Stud. 2017 Sep 19;3:44. doi: 10.1186/s40814-017-0179-y. eCollection 2017.


Bioconcentration of polycyclic musks in fathead minnows caged in a wastewater effluent plume.

Lefebvre C, Kimpe LE, Metcalfe CD, Trudeau VL, Blais JM.

Environ Pollut. 2017 Dec;231(Pt 2):1593-1600. doi: 10.1016/j.envpol.2017.09.062. Epub 2017 Sep 28.


Evaluation of wastewater treatment by ozonation for reducing the toxicity of contaminants of emerging concern to rainbow trout (Oncorhynchus mykiss).

Maya N, Evans J, Nasuhoglu D, Isazadeh S, Yargeau V, Metcalfe CD.

Environ Toxicol Chem. 2018 Jan;37(1):274-284. doi: 10.1002/etc.3952. Epub 2017 Oct 11.


Effectiveness of household lockable pesticide storage to reduce pesticide self-poisoning in rural Asia: a community-based, cluster-randomised controlled trial.

Pearson M, Metcalfe C, Jayamanne S, Gunnell D, Weerasinghe M, Pieris R, Priyadarshana C, Knipe DW, Hawton K, Dawson AH, Bandara P, deSilva D, Gawarammana I, Eddleston M, Konradsen F.

Lancet. 2017 Oct 21;390(10105):1863-1872. doi: 10.1016/S0140-6736(17)31961-X. Epub 2017 Aug 11. Erratum in: Lancet. 2017 Dec 9;390(10112):2548.


Toxicity of extracts from municipal wastewater to early life stages of Japanese medaka (Oryzias latipes) to evaluate removals of micropollutants by wastewater treatment.

Maya N, Crispo C, McFarland V, Nasuhoglu D, Isazadeh S, Yargeau V, Metcalfe CD.

Environ Toxicol Chem. 2018 Jan;37(1):136-144. doi: 10.1002/etc.3939. Epub 2017 Nov 10.


A systematic review to identify and assess the effectiveness of alternatives for people over the age of 65 who are at risk of potentially avoidable hospital admission.

Huntley AL, Chalder M, Shaw ARG, Hollingworth W, Metcalfe C, Benger JR, Purdy S.

BMJ Open. 2017 Aug 1;7(7):e016236. doi: 10.1136/bmjopen-2017-016236. Review.


Assessing the effects of the antidepressant venlafaxine to fathead minnows exposed to environmentally relevant concentrations over a full life cycle.

Parrott JL, Metcalfe CD.

Environ Pollut. 2017 Oct;229:403-411. doi: 10.1016/j.envpol.2017.06.009. Epub 2017 Jun 13.


Correction: Suicide prevention through means restriction: Impact of the 2008-2011 pesticide restrictions on suicide in Sri Lanka.

Knipe DW, Chang SS, Dawson A, Eddleston M, Konradsen F, Metcalfe C, Gunnell D.

PLoS One. 2017 Apr 25;12(4):e0176750. doi: 10.1371/journal.pone.0176750. eCollection 2017.


The 'One in a Million' study: creating a database of UK primary care consultations.

Jepson M, Salisbury C, Ridd MJ, Metcalfe C, Garside L, Barnes RK.

Br J Gen Pract. 2017 May;67(658):e345-e351. doi: 10.3399/bjgp17X690521. Epub 2017 Apr 10.


Estimating removals of contaminants of emerging concern from wastewater treatment plants: The critical role of wastewater hydrodynamics.

Baalbaki Z, Sultana T, Metcalfe C, Yargeau V.

Chemosphere. 2017 Jul;178:439-448. doi: 10.1016/j.chemosphere.2017.03.070. Epub 2017 Mar 19.


A Method for Preparing Silver Nanoparticle Suspensions in Bulk for Ecotoxicity Testing and Ecological Risk Assessment.

Martin JD, Telgmann L, Metcalfe CD.

Bull Environ Contam Toxicol. 2017 May;98(5):589-594. doi: 10.1007/s00128-017-2067-9. Epub 2017 Mar 24.


Is socioeconomic position associated with risk of attempted suicide in rural Sri Lanka? A cross-sectional study of 165 000 individuals.

Knipe DW, Gunnell D, Pieris R, Priyadarshana C, Weerasinghe M, Pearson M, Jayamanne S, Dawson AH, Mohamed F, Gawarammana I, Hawton K, Konradsen F, Eddleston M, Metcalfe C.

BMJ Open. 2017 Mar 22;7(3):e014006. doi: 10.1136/bmjopen-2016-014006.


Coblation tonsillectomy: a systematic review and descriptive analysis.

Metcalfe C, Muzaffar J, Daultrey C, Coulson C.

Eur Arch Otorhinolaryngol. 2017 Jun;274(6):2637-2647. doi: 10.1007/s00405-017-4529-4. Epub 2017 Mar 18. Review.


Predictive accuracy of risk scales following self-harm: multicentre, prospective cohort study.

Quinlivan L, Cooper J, Meehan D, Longson D, Potokar J, Hulme T, Marsden J, Brand F, Lange K, Riseborough E, Page L, Metcalfe C, Davies L, O'Connor R, Hawton K, Gunnell D, Kapur N.

Br J Psychiatry. 2017 Jun;210(6):429-436. doi: 10.1192/bjp.bp.116.189993. Epub 2017 Mar 16.


Development of a Core Outcome Set for Clinical Effectiveness Trials in Esophageal Cancer Resection Surgery.

Avery KNL, Chalmers KA, Brookes ST, Blencowe NS, Coulman K, Whale K, Metcalfe C, Blazeby JM; ROMIO Study Group; CONSENSUS Esophageal Cancer Working Group.

Ann Surg. 2018 Apr;267(4):700-710. doi: 10.1097/SLA.0000000000002204.


Suicide prevention through means restriction: Impact of the 2008-2011 pesticide restrictions on suicide in Sri Lanka.

Knipe DW, Chang SS, Dawson A, Eddleston M, Konradsen F, Metcalfe C, Gunnell D.

PLoS One. 2017 Mar 6;12(3):e0172893. doi: 10.1371/journal.pone.0172893. eCollection 2017. Erratum in: PLoS One. 2017 Apr 25;12 (4):e0176750.


Informing efficient randomised controlled trials: exploration of challenges in developing progression criteria for internal pilot studies.

Avery KN, Williamson PR, Gamble C, O'Connell Francischetto E, Metcalfe C, Davidson P, Williams H, Blazeby JM; members of the Internal Pilot Trials Workshop supported by the Hubs for Trials Methodology Research.

BMJ Open. 2017 Feb 17;7(2):e013537. doi: 10.1136/bmjopen-2016-013537. Review.


Regional variation in suicide rates in Sri Lanka between 1955 and 2011: a spatial and temporal analysis.

Knipe DW, Padmanathan P, Muthuwatta L, Metcalfe C, Gunnell D.

BMC Public Health. 2017 Feb 14;17(1):193. doi: 10.1186/s12889-016-3961-5.


Does exposure to opioid substitution treatment in prison reduce the risk of death after release? A national prospective observational study in England.

Marsden J, Stillwell G, Jones H, Cooper A, Eastwood B, Farrell M, Lowden T, Maddalena N, Metcalfe C, Shaw J, Hickman M.

Addiction. 2017 Aug;112(8):1408-1418. doi: 10.1111/add.13779. Epub 2017 Mar 1.


Photocatalytic Degradation of Contaminants with Titanium Dioxide: A 40-Year Retrospective on the Paper by John Carey and Colleagues Published in BECT.

Yargeau V, Metcalfe CD.

Bull Environ Contam Toxicol. 2017 Feb;98(2):147-148. doi: 10.1007/s00128-016-2021-2. Epub 2017 Jan 18. No abstract available.


Interventions to reduce the impact of unemployment and economic hardship on mental health in the general population: a systematic review.

Moore TH, Kapur N, Hawton K, Richards A, Metcalfe C, Gunnell D.

Psychol Med. 2017 Apr;47(6):1062-1084. doi: 10.1017/S0033291716002944. Epub 2016 Dec 15. Review.


Monitoring contaminants of emerging concern from tertiary wastewater treatment plants using passive sampling modelled with performance reference compounds.

Sultana T, Murray C, Ehsanul Hoque M, Metcalfe CD.

Environ Monit Assess. 2016 Dec;189(1):1. Epub 2016 Dec 1.


Choice of Moisturiser for Eczema Treatment (COMET): feasibility study of a randomised controlled parallel group trial in children recruited from primary care.

Ridd MJ, Garfield K, Gaunt DM, Hollinghurst S, Redmond NM, Powell K, Wilson V, Guy RH, Ball N, Shaw L, Purdy S, Metcalfe C.

BMJ Open. 2016 Nov 16;6(11):e012021. doi: 10.1136/bmjopen-2016-012021.


Diffusion-weighted magnetic resonance imaging for residual and recurrent cholesteatoma: a systematic review and meta-analysis.

Muzaffar J, Metcalfe C, Colley S, Coulson C.

Clin Otolaryngol. 2017 Jun;42(3):536-543. doi: 10.1111/coa.12762. Epub 2016 Nov 3. Review.


Homodimerization of the Lymph Vessel Endothelial Receptor LYVE-1 through a Redox-labile Disulfide Is Critical for Hyaluronan Binding in Lymphatic Endothelium.

Banerji S, Lawrance W, Metcalfe C, Briggs DC, Yamauchi A, Dushek O, van der Merwe PA, Day AJ, Jackson DG.

J Biol Chem. 2016 Nov 25;291(48):25004-25018. Epub 2016 Oct 12.


Thioredoxin Inhibitors Attenuate Platelet Function and Thrombus Formation.

Metcalfe C, Ramasubramoni A, Pula G, Harper MT, Mundell SJ, Coxon CH.

PLoS One. 2016 Oct 7;11(10):e0163006. doi: 10.1371/journal.pone.0163006. eCollection 2016.


Fate and mass balance of contaminants of emerging concern during wastewater treatment determined using the fractionated approach.

Baalbaki Z, Sultana T, Maere T, Vanrolleghem PA, Metcalfe CD, Yargeau V.

Sci Total Environ. 2016 Dec 15;573:1147-1158. doi: 10.1016/j.scitotenv.2016.08.073. Epub 2016 Oct 2.


Biomarkers of exposure to nanosilver and silver accumulation in yellow perch (Perca flavescens).

Martin JD, Colson TL, Langlois VS, Metcalfe CD.

Environ Toxicol Chem. 2017 May;36(5):1211-1220. doi: 10.1002/etc.3644. Epub 2016 Nov 7.


Robot-assisted Level II-III Inferior Vena Cava Tumor Thrombectomy: Step-by-Step Technique and 1-Year Outcomes.

Chopra S, Simone G, Metcalfe C, de Castro Abreu AL, Nabhani J, Ferriero M, Bove AM, Sotelo R, Aron M, Desai MM, Gallucci M, Gill IS.

Eur Urol. 2017 Aug;72(2):267-274. doi: 10.1016/j.eururo.2016.08.066. Epub 2016 Sep 20.


Patient-Reported Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer.

Donovan JL, Hamdy FC, Lane JA, Mason M, Metcalfe C, Walsh E, Blazeby JM, Peters TJ, Holding P, Bonnington S, Lennon T, Bradshaw L, Cooper D, Herbert P, Howson J, Jones A, Lyons N, Salter E, Thompson P, Tidball S, Blaikie J, Gray C, Bollina P, Catto J, Doble A, Doherty A, Gillatt D, Kockelbergh R, Kynaston H, Paul A, Powell P, Prescott S, Rosario DJ, Rowe E, Davis M, Turner EL, Martin RM, Neal DE; ProtecT Study Group*.

N Engl J Med. 2016 Oct 13;375(15):1425-1437. doi: 10.1056/NEJMoa1606221. Epub 2016 Sep 14.


10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer.

Hamdy FC, Donovan JL, Lane JA, Mason M, Metcalfe C, Holding P, Davis M, Peters TJ, Turner EL, Martin RM, Oxley J, Robinson M, Staffurth J, Walsh E, Bollina P, Catto J, Doble A, Doherty A, Gillatt D, Kockelbergh R, Kynaston H, Paul A, Powell P, Prescott S, Rosario DJ, Rowe E, Neal DE; ProtecT Study Group.

N Engl J Med. 2016 Oct 13;375(15):1415-1424. doi: 10.1056/NEJMoa1606220. Epub 2016 Sep 14.


Patient safety in otolaryngology: a descriptive review.

Danino J, Muzaffar J, Metcalfe C, Coulson C.

Eur Arch Otorhinolaryngol. 2017 Mar;274(3):1317-1326. doi: 10.1007/s00405-016-4291-z. Epub 2016 Sep 13. Review.


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