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Items: 27

1.

NOX4 deletion in male mice exacerbates the effect of ethanol on trabecular bone and osteoblastogenesis.

Watt J, Alund AW, Pulliam CF, Mercer KE, Suva LJ, Chen JR, Ronis MJJ.

J Pharmacol Exp Ther. 2018 Apr 13. pii: jpet.117.247262. doi: 10.1124/jpet.117.247262. [Epub ahead of print]

2.

Formula diet driven microbiota shifts tryptophan metabolism from serotonin to tryptamine in neonatal porcine colon.

Saraf MK, Piccolo BD, Bowlin AK, Mercer KE, LeRoith T, Chintapalli SV, Shankar K, Badger TM, Yeruva L.

Microbiome. 2017 Jul 14;5(1):77. doi: 10.1186/s40168-017-0297-z.

3.

Early Postnatal Diets Affect the Bioregional Small Intestine Microbiome and Ileal Metabolome in Neonatal Pigs.

Piccolo BD, Mercer KE, Bhattacharyya S, Bowlin AK, Saraf MK, Pack L, Chintapalli SV, Shankar K, Adams SH, Badger TM, Yeruva L.

J Nutr. 2017 Aug;147(8):1499-1509. doi: 10.3945/jn.117.252767. Epub 2017 Jun 28.

PMID:
28659406
4.

Soy protein isolate inhibits hepatic tumor promotion in mice fed a high-fat liquid diet.

Mercer KE, Pulliam CF, Pedersen KB, Hennings L, Ronis MJ.

Exp Biol Med (Maywood). 2017 Mar;242(6):635-644. doi: 10.1177/1535370216685436. Epub 2017 Jan 5.

5.

Partial Protection by Dietary Antioxidants Against Ethanol-Induced Osteopenia and Changes in Bone Morphology in Female Mice.

Alund AW, Mercer KE, Pulliam CF, Suva LJ, Chen JR, Badger TM, Ronis MJ.

Alcohol Clin Exp Res. 2017 Jan;41(1):46-56. doi: 10.1111/acer.13284. Epub 2016 Dec 17.

6.

Reactive Oxygen Species Differentially Regulate Bone Turnover in an Age-Specific Manner in Catalase Transgenic Female Mice.

Alund AW, Mercer KE, Suva LJ, Pulliam CF, Chen JR, Badger TM, Van Remmen H, Ronis MJ.

J Pharmacol Exp Ther. 2016 Jul;358(1):50-60. doi: 10.1124/jpet.116.233213. Epub 2016 May 12.

7.

Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage.

Shearn CT, Orlicky DJ, McCullough RL, Jiang H, Maclean KN, Mercer KE, Stiles BL, Saba LM, Ronis MJ, Petersen DR.

PLoS One. 2016 Apr 28;11(4):e0154152. doi: 10.1371/journal.pone.0154152. eCollection 2016.

8.

Soy Protein Isolate Protects Against Ethanol-Mediated Tumor Progression in Diethylnitrosamine-Treated Male Mice.

Mercer KE, Pulliam C, Hennings L, Lai K, Cleves M, Jones E, Drake RR, Ronis M.

Cancer Prev Res (Phila). 2016 Jun;9(6):466-75. doi: 10.1158/1940-6207.CAPR-15-0417. Epub 2016 Mar 22.

9.

Deletion of GSTA4-4 results in increased mitochondrial post-translational modification of proteins by reactive aldehydes following chronic ethanol consumption in mice.

Shearn CT, Fritz KS, Shearn AH, Saba LM, Mercer KE, Engi B, Galligan JJ, Zimniak P, Orlicky DJ, Ronis MJ, Petersen DR.

Redox Biol. 2016 Apr;7:68-77. doi: 10.1016/j.redox.2015.11.013. Epub 2015 Nov 27.

10.

p47phox-Nox2-dependent ROS Signaling Inhibits Early Bone Development in Mice but Protects against Skeletal Aging.

Chen JR, Lazarenko OP, Blackburn ML, Mercer KE, Badger TM, Ronis MJ.

J Biol Chem. 2015 Jun 5;290(23):14692-704. doi: 10.1074/jbc.M114.633461. Epub 2015 Apr 28.

11.

Increased 4-hydroxynonenal protein adducts in male GSTA4-4/PPAR-α double knockout mice enhance injury during early stages of alcoholic liver disease.

Ronis MJ, Mercer KE, Gannon B, Engi B, Zimniak P, Shearn CT, Orlicky DJ, Albano E, Badger TM, Petersen DR.

Am J Physiol Gastrointest Liver Physiol. 2015 Mar 1;308(5):G403-15. doi: 10.1152/ajpgi.00154.2014. Epub 2014 Dec 11.

12.

Alcohol consumption, Wnt/β-catenin signaling, and hepatocarcinogenesis.

Mercer KE, Hennings L, Ronis MJ.

Adv Exp Med Biol. 2015;815:185-95. doi: 10.1007/978-3-319-09614-8_11. Review.

13.

Genistein supplementation increases bone turnover but does not prevent alcohol-induced bone loss in male mice.

Yang CS, Mercer KE, Alund AW, Suva LJ, Badger TM, Ronis MJ.

Exp Biol Med (Maywood). 2014 Oct;239(10):1380-9. doi: 10.1177/1535370214532759. Epub 2014 May 28.

14.

Short term feeding of a high fat diet exerts an additive effect on hepatocellular damage and steatosis in liver-specific PTEN knockout mice.

Shearn CT, Mercer KE, Orlicky DJ, Hennings L, Smathers-McCullough RL, Stiles BL, Ronis MJ, Petersen DR.

PLoS One. 2014 May 12;9(5):e96553. doi: 10.1371/journal.pone.0096553. eCollection 2014.

15.

Alcohol consumption promotes diethylnitrosamine-induced hepatocarcinogenesis in male mice through activation of the Wnt/β-catenin signaling pathway.

Mercer KE, Hennings L, Sharma N, Lai K, Cleves MA, Wynne RA, Badger TM, Ronis MJ.

Cancer Prev Res (Phila). 2014 Jul;7(7):675-85. doi: 10.1158/1940-6207.CAPR-13-0444-T. Epub 2014 Apr 28.

16.

Loss of functional NADPH oxidase 2 protects against alcohol-induced bone resorption in female p47phox-/- mice.

Mercer KE, Sims CR, Yang CS, Wynne RA, Moutos C, Hogue WR, Lumpkin CK, Suva LJ, Chen JR, Badger TM, Ronis MJ.

Alcohol Clin Exp Res. 2014 Mar;38(3):672-82. doi: 10.1111/acer.12305. Epub 2013 Nov 20.

17.

Female mice lacking p47phox have altered adipose tissue gene expression and are protected against high fat-induced obesity.

Ronis MJ, Sharma N, Vantrease J, Borengasser SJ, Ferguson M, Mercer KE, Cleves MA, Gomez-Acevedo H, Badger TM.

Physiol Genomics. 2013 May 1;45(9):351-66. doi: 10.1152/physiolgenomics.00148.2012. Epub 2013 Mar 12.

PMID:
23482812
18.

Vitamin D supplementation protects against bone loss associated with chronic alcohol administration in female mice.

Mercer KE, Wynne RA, Lazarenko OP, Lumpkin CK, Hogue WR, Suva LJ, Chen JR, Mason AZ, Badger TM, Ronis MJ.

J Pharmacol Exp Ther. 2012 Nov;343(2):401-12. doi: 10.1124/jpet.112.197038. Epub 2012 Aug 14.

19.

Expression of sulfotransferase isoform 1A1 (SULT1A1) in breast cancer cells significantly increases 4-hydroxytamoxifen-induced apoptosis.

Mercer KE, Apostolov EO, Gamboa da Costa G, Yu X, Lang P, Roberts DW, Davis W, Basnakian AG, Kadlubar FF, Kadlubar SA.

Int J Mol Epidemiol Genet. 2010 Jan 30;1(2):92-103.

20.

Evidence of structure-selective fragmentations in the tandem mass spectra of protonated hydroxyalkylamino-1,4-naphthoquinones formed by electrospray ionisation.

Bowen RD, Mahmood T, Maitland DJ, Mercer KE, Gallagher RT.

Eur J Mass Spectrom (Chichester). 2009;15(5):617-26. doi: 10.1255/ejms.1023.

PMID:
19679942
21.

Identification of a mammalian mitochondrial porphyrin transporter.

Krishnamurthy PC, Du G, Fukuda Y, Sun D, Sampath J, Mercer KE, Wang J, Sosa-Pineda B, Murti KG, Schuetz JD.

Nature. 2006 Oct 5;443(7111):586-9. Epub 2006 Sep 27.

PMID:
17006453
22.

Photothermal nanotherapeutics and nanodiagnostics for selective killing of bacteria targeted with gold nanoparticles.

Zharov VP, Mercer KE, Galitovskaya EN, Smeltzer MS.

Biophys J. 2006 Jan 15;90(2):619-27. Epub 2005 Oct 20.

23.

Mrp4 confers resistance to topotecan and protects the brain from chemotherapy.

Leggas M, Adachi M, Scheffer GL, Sun D, Wielinga P, Du G, Mercer KE, Zhuang Y, Panetta JC, Johnston B, Scheper RJ, Stewart CF, Schuetz JD.

Mol Cell Biol. 2004 Sep;24(17):7612-21.

24.

The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme.

Krishnamurthy P, Ross DD, Nakanishi T, Bailey-Dell K, Zhou S, Mercer KE, Sarkadi B, Sorrentino BP, Schuetz JD.

J Biol Chem. 2004 Jun 4;279(23):24218-25. Epub 2004 Mar 24.

25.

Raf proteins and cancer: B-Raf is identified as a mutational target.

Mercer KE, Pritchard CA.

Biochim Biophys Acta. 2003 Jun 5;1653(1):25-40. Review.

PMID:
12781369
26.

Mutation of herpesvirus thymidine kinase to generate ganciclovir-specific kinases for use in cancer gene therapies.

Mercer KE, Ahn CE, Coke A, Compadre CM, Drake RR.

Protein Eng. 2002 Nov;15(11):903-11.

PMID:
12538910
27.

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