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Items: 1 to 50 of 106

1.

Venous thromboembolism risk and postpartum lying-in: Acculturation of Indian and Chinese women.

Melov SJ, Hitos K.

Midwifery. 2018 Mar;58:13-18. doi: 10.1016/j.midw.2017.11.006. Epub 2017 Dec 5.

PMID:
29275264
2.

mTORC1 Activation during Repeated Regeneration Impairs Somatic Stem Cell Maintenance.

Haller S, Kapuria S, Riley RR, O'Leary MN, Schreiber KH, Andersen JK, Melov S, Que J, Rando TA, Rock J, Kennedy BK, Rodgers JT, Jasper H.

Cell Stem Cell. 2017 Dec 7;21(6):806-818.e5. doi: 10.1016/j.stem.2017.11.008.

PMID:
29220665
3.

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Zillikens MC, Demissie S, Hsu YH, Yerges-Armstrong LM, Chou WC, Stolk L, Livshits G, Broer L, Johnson T, Koller DL, Kutalik Z, Luan J, Malkin I, Ried JS, Smith AV, Thorleifsson G, Vandenput L, Hua Zhao J, Zhang W, Aghdassi A, Åkesson K, Amin N, Baier LJ, Barroso I, Bennett DA, Bertram L, Biffar R, Bochud M, Boehnke M, Borecki IB, Buchman AS, Byberg L, Campbell H, Campos Obanda N, Cauley JA, Cawthon PM, Cederberg H, Chen Z, Cho NH, Jin Choi H, Claussnitzer M, Collins F, Cummings SR, De Jager PL, Demuth I, Dhonukshe-Rutten RAM, Diatchenko L, Eiriksdottir G, Enneman AW, Erdos M, Eriksson JG, Eriksson J, Estrada K, Evans DS, Feitosa MF, Fu M, Garcia M, Gieger C, Girke T, Glazer NL, Grallert H, Grewal J, Han BG, Hanson RL, Hayward C, Hofman A, Hoffman EP, Homuth G, Hsueh WC, Hubal MJ, Hubbard A, Huffman KM, Husted LB, Illig T, Ingelsson E, Ittermann T, Jansson JO, Jordan JM, Jula A, Karlsson M, Khaw KT, Kilpeläinen TO, Klopp N, Kloth JSL, Koistinen HA, Kraus WE, Kritchevsky S, Kuulasmaa T, Kuusisto J, Laakso M, Lahti J, Lang T, Langdahl BL, Launer LJ, Lee JY, Lerch MM, Lewis JR, Lind L, Lindgren C, Liu Y, Liu T, Liu Y, Ljunggren Ö, Lorentzon M, Luben RN, Maixner W, McGuigan FE, Medina-Gomez C, Meitinger T, Melhus H, Mellström D, Melov S, Michaëlsson K, Mitchell BD, Morris AP, Mosekilde L, Newman A, Nielson CM, O'Connell JR, Oostra BA, Orwoll ES, Palotie A, Parker SCJ, Peacock M, Perola M, Peters A, Polasek O, Prince RL, Räikkönen K, Ralston SH, Ripatti S, Robbins JA, Rotter JI, Rudan I, Salomaa V, Satterfield S, Schadt EE, Schipf S, Scott L, Sehmi J, Shen J, Soo Shin C, Sigurdsson G, Smith S, Soranzo N, Stančáková A, Steinhagen-Thiessen E, Streeten EA, Styrkarsdottir U, Swart KMA, Tan ST, Tarnopolsky MA, Thompson P, Thomson CA, Thorsteinsdottir U, Tikkanen E, Tranah GJ, Tuomilehto J, van Schoor NM, Verma A, Vollenweider P, Völzke H, Wactawski-Wende J, Walker M, Weedon MN, Welch R, Wichmann HE, Widen E, Williams FMK, Wilson JF, Wright NC, Xie W, Yu L, Zhou Y, Chambers JC, Döring A, van Duijn CM, Econs MJ, Gudnason V, Kooner JS, Psaty BM, Spector TD, Stefansson K, Rivadeneira F, Uitterlinden AG, Wareham NJ, Ossowski V, Waterworth D, Loos RJF, Karasik D, Harris TB, Ohlsson C, Kiel DP.

Nat Commun. 2017 Nov 7;8(1):1414. doi: 10.1038/s41467-017-01008-2.

4.

Unmasking Transcriptional Heterogeneity in Senescent Cells.

Hernandez-Segura A, de Jong TV, Melov S, Guryev V, Campisi J, Demaria M.

Curr Biol. 2017 Sep 11;27(17):2652-2660.e4. doi: 10.1016/j.cub.2017.07.033. Epub 2017 Aug 30.

5.

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Zillikens MC, Demissie S, Hsu YH, Yerges-Armstrong LM, Chou WC, Stolk L, Livshits G, Broer L, Johnson T, Koller DL, Kutalik Z, Luan J, Malkin I, Ried JS, Smith AV, Thorleifsson G, Vandenput L, Hua Zhao J, Zhang W, Aghdassi A, Åkesson K, Amin N, Baier LJ, Barroso I, Bennett DA, Bertram L, Biffar R, Bochud M, Boehnke M, Borecki IB, Buchman AS, Byberg L, Campbell H, Campos Obanda N, Cauley JA, Cawthon PM, Cederberg H, Chen Z, Cho NH, Jin Choi H, Claussnitzer M, Collins F, Cummings SR, De Jager PL, Demuth I, Dhonukshe-Rutten RAM, Diatchenko L, Eiriksdottir G, Enneman AW, Erdos M, Eriksson JG, Eriksson J, Estrada K, Evans DS, Feitosa MF, Fu M, Garcia M, Gieger C, Girke T, Glazer NL, Grallert H, Grewal J, Han BG, Hanson RL, Hayward C, Hofman A, Hoffman EP, Homuth G, Hsueh WC, Hubal MJ, Hubbard A, Huffman KM, Husted LB, Illig T, Ingelsson E, Ittermann T, Jansson JO, Jordan JM, Jula A, Karlsson M, Khaw KT, Kilpeläinen TO, Klopp N, Kloth JSL, Koistinen HA, Kraus WE, Kritchevsky S, Kuulasmaa T, Kuusisto J, Laakso M, Lahti J, Lang T, Langdahl BL, Launer LJ, Lee JY, Lerch MM, Lewis JR, Lind L, Lindgren C, Liu Y, Liu T, Liu Y, Ljunggren Ö, Lorentzon M, Luben RN, Maixner W, McGuigan FE, Medina-Gomez C, Meitinger T, Melhus H, Mellström D, Melov S, Michaëlsson K, Mitchell BD, Morris AP, Mosekilde L, Newman A, Nielson CM, O'Connell JR, Oostra BA, Orwoll ES, Palotie A, Parker SCJ, Peacock M, Perola M, Peters A, Polasek O, Prince RL, Räikkönen K, Ralston SH, Ripatti S, Robbins JA, Rotter JI, Rudan I, Salomaa V, Satterfield S, Schadt EE, Schipf S, Scott L, Sehmi J, Shen J, Soo Shin C, Sigurdsson G, Smith S, Soranzo N, Stančáková A, Steinhagen-Thiessen E, Streeten EA, Styrkarsdottir U, Swart KMA, Tan ST, Tarnopolsky MA, Thompson P, Thomson CA, Thorsteinsdottir U, Tikkanen E, Tranah GJ, Tuomilehto J, van Schoor NM, Verma A, Vollenweider P, Völzke H, Wactawski-Wende J, Walker M, Weedon MN, Welch R, Wichmann HE, Widen E, Williams FMK, Wilson JF, Wright NC, Xie W, Yu L, Zhou Y, Chambers JC, Döring A, van Duijn CM, Econs MJ, Gudnason V, Kooner JS, Psaty BM, Spector TD, Stefansson K, Rivadeneira F, Uitterlinden AG, Wareham NJ, Ossowski V, Waterworth D, Loos RJF, Karasik D, Harris TB, Ohlsson C, Kiel DP.

Nat Commun. 2017 Jul 19;8(1):80. doi: 10.1038/s41467-017-00031-7. Erratum in: Nat Commun. 2017 Nov 7;8(1):1414.

6.

Analysis of individual cells identifies cell-to-cell variability following induction of cellular senescence.

Wiley CD, Flynn JM, Morrissey C, Lebofsky R, Shuga J, Dong X, Unger MA, Vijg J, Melov S, Campisi J.

Aging Cell. 2017 Oct;16(5):1043-1050. doi: 10.1111/acel.12632. Epub 2017 Jul 11.

7.
8.

Long-term calorie restriction in humans is not associated with indices of delayed immunologic aging: A descriptive study.

Tomiyama AJ, Milush JM, Lin J, Flynn JM, Kapahi P, Verdin E, Sinclair E, Melov S, Epel ES.

Nutr Healthy Aging. 2017 Mar 31;4(2):147-156. doi: 10.3233/NHA-160017.

9.

Who is and isn't having babies with Down syndrome in western Sydney: a ten year hospital cohort study.

Moses RM, Brown JH, Wright DC, Diplock H, Melov SJ, McGee TM.

Aust N Z J Obstet Gynaecol. 2017 Apr;57(2):146-151. doi: 10.1111/ajo.12617. Epub 2017 Mar 29.

PMID:
28369907
10.

Adrenergic Receptors in Individual Ventricular Myocytes: The Beta-1 and Alpha-1B Are in All Cells, the Alpha-1A Is in a Subpopulation, and the Beta-2 and Beta-3 Are Mostly Absent.

Myagmar BE, Flynn JM, Cowley PM, Swigart PM, Montgomery MD, Thai K, Nair D, Gupta R, Deng DX, Hosoda C, Melov S, Baker AJ, Simpson PC.

Circ Res. 2017 Mar 31;120(7):1103-1115. doi: 10.1161/CIRCRESAHA.117.310520. Epub 2017 Feb 20.

11.

A perinatal review of singleton stillbirths in an Australian metropolitan tertiary centre.

Kapurubandara S, Melov SJ, Shalou ER, Mukerji M, Yim S, Rao U, Battikhi Z, Karunaratne N, Nayyar R, Alahakoon TI.

PLoS One. 2017 Feb 13;12(2):e0171829. doi: 10.1371/journal.pone.0171829. eCollection 2017.

12.

Expression patterns of cardiac aging in Drosophila.

Cannon L, Zambon AC, Cammarato A, Zhang Z, Vogler G, Munoz M, Taylor E, Cartry J, Bernstein SI, Melov S, Bodmer R.

Aging Cell. 2017 Feb;16(1):82-92. doi: 10.1111/acel.12559.

13.

Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing.

Zhang Y, O'Leary MN, Peri S, Wang M, Zha J, Melov S, Kappes DJ, Feng Q, Rhodes J, Amieux PS, Morris DR, Kennedy BK, Wiest DL.

Cell Rep. 2017 Jan 10;18(2):545-556. doi: 10.1016/j.celrep.2016.12.034.

14.

Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse.

Demaria M, O'Leary MN, Chang J, Shao L, Liu S, Alimirah F, Koenig K, Le C, Mitin N, Deal AM, Alston S, Academia EC, Kilmarx S, Valdovinos A, Wang B, de Bruin A, Kennedy BK, Melov S, Zhou D, Sharpless NE, Muss H, Campisi J.

Cancer Discov. 2017 Feb;7(2):165-176. doi: 10.1158/2159-8290.CD-16-0241. Epub 2016 Dec 15.

15.

Uncovering the Dark Energy of Aging.

Melov S.

Cell Syst. 2016 Oct 26;3(4):328-330. doi: 10.1016/j.cels.2016.10.001.

16.

Vitamin D Promotes Protein Homeostasis and Longevity via the Stress Response Pathway Genes skn-1, ire-1, and xbp-1.

Mark KA, Dumas KJ, Bhaumik D, Schilling B, Davis S, Oron TR, Sorensen DJ, Lucanic M, Brem RB, Melov S, Ramanathan A, Gibson BW, Lithgow GJ.

Cell Rep. 2016 Oct 25;17(5):1227-1237. doi: 10.1016/j.celrep.2016.09.086.

17.

Suppressors of Superoxide-H2O2 Production at Site IQ of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury.

Brand MD, Goncalves RL, Orr AL, Vargas L, Gerencser AA, Borch Jensen M, Wang YT, Melov S, Turk CN, Matzen JT, Dardov VJ, Petrassi HM, Meeusen SL, Perevoshchikova IV, Jasper H, Brookes PS, Ainscow EK.

Cell Metab. 2016 Oct 11;24(4):582-592. doi: 10.1016/j.cmet.2016.08.012. Epub 2016 Sep 22.

18.

Consanguinity and associated perinatal outcomes, including stillbirth.

Kapurubandara S, Melov S, Shalou E, Alahakoon I.

Aust N Z J Obstet Gynaecol. 2016 Dec;56(6):599-604. doi: 10.1111/ajo.12493. Epub 2016 Jul 11.

PMID:
27396579
19.

Geroscience approaches to increase healthspan and slow aging.

Melov S.

F1000Res. 2016 Apr 29;5. pii: F1000 Faculty Rev-785. doi: 10.12688/f1000research.7583.1. eCollection 2016. Review.

20.

Genomic Analysis Reveals Disruption of Striatal Neuronal Development and Therapeutic Targets in Human Huntington's Disease Neural Stem Cells.

Ring KL, An MC, Zhang N, O'Brien RN, Ramos EM, Gao F, Atwood R, Bailus BJ, Melov S, Mooney SD, Coppola G, Ellerby LM.

Stem Cell Reports. 2015 Dec 8;5(6):1023-1038. doi: 10.1016/j.stemcr.2015.11.005.

21.

Pleiotropic age-dependent effects of mitochondrial dysfunction on epidermal stem cells.

Velarde MC, Demaria M, Melov S, Campisi J.

Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):10407-12. doi: 10.1073/pnas.1505675112. Epub 2015 Aug 3.

22.

Translational geroscience: emphasizing function to achieve optimal longevity.

Seals DR, Melov S.

Aging (Albany NY). 2014 Sep;6(9):718-30.

23.

Medical research: treat ageing.

Fontana L, Kennedy BK, Longo VD, Seals D, Melov S.

Nature. 2014 Jul 24;511(7510):405-7. doi: 10.1038/511405a. No abstract available.

PMID:
25056047
24.

Germline signaling mediates the synergistically prolonged longevity produced by double mutations in daf-2 and rsks-1 in C. elegans.

Chen D, Li PW, Goldstein BA, Cai W, Thomas EL, Chen F, Hubbard AE, Melov S, Kapahi P.

Cell Rep. 2013 Dec 26;5(6):1600-10. doi: 10.1016/j.celrep.2013.11.018. Epub 2013 Dec 12.

25.

Genome-wide DNA methylation changes with age in disease-free human skeletal muscle.

Zykovich A, Hubbard A, Flynn JM, Tarnopolsky M, Fraga MF, Kerksick C, Ogborn D, MacNeil L, Mooney SD, Melov S.

Aging Cell. 2014 Apr;13(2):360-6. doi: 10.1111/acel.12180. Epub 2013 Dec 2.

26.

Age-related micro-RNA abundance in individual C. elegans.

Lucanic M, Graham J, Scott G, Bhaumik D, Benz CC, Hubbard A, Lithgow GJ, Melov S.

Aging (Albany NY). 2013 Jun;5(6):394-411.

27.

Late-life rapamycin treatment reverses age-related heart dysfunction.

Flynn JM, O'Leary MN, Zambataro CA, Academia EC, Presley MP, Garrett BJ, Zykovich A, Mooney SD, Strong R, Rosen CJ, Kapahi P, Nelson MD, Kennedy BK, Melov S.

Aging Cell. 2013 Oct;12(5):851-62. doi: 10.1111/acel.12109. Epub 2013 Jul 7.

28.

SOD2 in mitochondrial dysfunction and neurodegeneration.

Flynn JM, Melov S.

Free Radic Biol Med. 2013 Sep;62:4-12. doi: 10.1016/j.freeradbiomed.2013.05.027. Epub 2013 May 29. Review.

29.

Single cell gene expression profiling of cortical osteoblast lineage cells.

Flynn JM, Spusta SC, Rosen CJ, Melov S.

Bone. 2013 Mar;53(1):174-81. doi: 10.1016/j.bone.2012.11.043. Epub 2012 Dec 10.

30.

No consistent bioenergetic defects in presynaptic nerve terminals isolated from mouse models of Alzheimer's disease.

Choi SW, Gerencser AA, Ng R, Flynn JM, Melov S, Danielson SR, Gibson BW, Nicholls DG, Bredesen DE, Brand MD.

J Neurosci. 2012 Nov 21;32(47):16775-84. doi: 10.1523/JNEUROSCI.2414-12.2012.

31.

Proteogenomics of synaptosomal mitochondrial oxidative stress.

Flynn JM, Czerwieniec GA, Choi SW, Day NU, Gibson BW, Hubbard A, Melov S.

Free Radic Biol Med. 2012 Sep 1;53(5):1048-60. doi: 10.1016/j.freeradbiomed.2012.07.004. Epub 2012 Jul 13.

32.

Intramyocellular fatty-acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster.

Katewa SD, Demontis F, Kolipinski M, Hubbard A, Gill MS, Perrimon N, Melov S, Kapahi P.

Cell Metab. 2012 Jul 3;16(1):97-103. doi: 10.1016/j.cmet.2012.06.005.

33.

Genetic correction of Huntington's disease phenotypes in induced pluripotent stem cells.

An MC, Zhang N, Scott G, Montoro D, Wittkop T, Mooney S, Melov S, Ellerby LM.

Cell Stem Cell. 2012 Aug 3;11(2):253-63. doi: 10.1016/j.stem.2012.04.026. Epub 2012 Jun 28.

34.

Selective binding of nuclear alpha-synuclein to the PGC1alpha promoter under conditions of oxidative stress may contribute to losses in mitochondrial function: implications for Parkinson's disease.

Siddiqui A, Chinta SJ, Mallajosyula JK, Rajagopolan S, Hanson I, Rane A, Melov S, Andersen JK.

Free Radic Biol Med. 2012 Aug 15;53(4):993-1003. doi: 10.1016/j.freeradbiomed.2012.05.024. Epub 2012 Jun 15.

35.

Premature expression of a muscle fibrosis axis in chronic HIV infection.

Kusko RL, Banerjee C, Long KK, Darcy A, Otis J, Sebastiani P, Melov S, Tarnopolsky M, Bhasin S, Montano M.

Skelet Muscle. 2012 Jun 7;2(1):10. doi: 10.1186/2044-5040-2-10.

36.

cep-1/p53-dependent dysplastic pathology of the aging C. elegans gonad.

McGee MD, Day N, Graham J, Melov S.

Aging (Albany NY). 2012 Apr;4(4):256-69.

37.

Massage therapy attenuates inflammatory signaling after exercise-induced muscle damage.

Crane JD, Ogborn DI, Cupido C, Melov S, Hubbard A, Bourgeois JM, Tarnopolsky MA.

Sci Transl Med. 2012 Feb 1;4(119):119ra13. doi: 10.1126/scitranslmed.3002882.

38.

Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin.

Velarde MC, Flynn JM, Day NU, Melov S, Campisi J.

Aging (Albany NY). 2012 Jan;4(1):3-12.

39.

Single cell transcriptional profiling of adult mouse cardiomyocytes.

Flynn JM, Santana LF, Melov S.

J Vis Exp. 2011 Dec 28;(58):e3302. doi: 10.3791/3302.

40.

Human embryonic stem cells express elevated levels of multiple pro-apoptotic BCL-2 family members.

Madden DT, Davila-Kruger D, Melov S, Bredesen DE.

PLoS One. 2011;6(12):e28530. doi: 10.1371/journal.pone.0028530. Epub 2011 Dec 9. Erratum in: PLoS One. 2012;7(9). doi:10.1371/annotation/38d5bc7f-42f2-4d1e-b293-1a003bb57812.

41.

On the programmed/non-programmed nature of ageing within the life history.

Kirkwood TB, Melov S.

Curr Biol. 2011 Sep 27;21(18):R701-7. doi: 10.1016/j.cub.2011.07.020. Review.

42.

Cellular senescence: a link between cancer and age-related degenerative disease?

Campisi J, Andersen JK, Kapahi P, Melov S.

Semin Cancer Biol. 2011 Dec;21(6):354-9. doi: 10.1016/j.semcancer.2011.09.001. Epub 2011 Sep 10. Review.

43.

Life span extension via eIF4G inhibition is mediated by posttranscriptional remodeling of stress response gene expression in C. elegans.

Rogers AN, Chen D, McColl G, Czerwieniec G, Felkey K, Gibson BW, Hubbard A, Melov S, Lithgow GJ, Kapahi P.

Cell Metab. 2011 Jul 6;14(1):55-66. doi: 10.1016/j.cmet.2011.05.010.

44.

Loss of intestinal nuclei and intestinal integrity in aging C. elegans.

McGee MD, Weber D, Day N, Vitelli C, Crippen D, Herndon LA, Hall DH, Melov S.

Aging Cell. 2011 Aug;10(4):699-710. doi: 10.1111/j.1474-9726.2011.00713.x. Epub 2011 May 25.

45.

Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice.

Safdar A, Bourgeois JM, Ogborn DI, Little JP, Hettinga BP, Akhtar M, Thompson JE, Melov S, Mocellin NJ, Kujoth GC, Prolla TA, Tarnopolsky MA.

Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):4135-40. doi: 10.1073/pnas.1019581108. Epub 2011 Feb 22.

46.

The garlic constituent diallyl trisulfide increases the lifespan of C. elegans via skn-1 activation.

Powolny AA, Singh SV, Melov S, Hubbard A, Fisher AL.

Exp Gerontol. 2011 Jun;46(6):441-52. doi: 10.1016/j.exger.2011.01.005. Epub 2011 Feb 2.

47.

Impaired spare respiratory capacity in cortical synaptosomes from Sod2 null mice.

Flynn JM, Choi SW, Day NU, Gerencser AA, Hubbard A, Melov S.

Free Radic Biol Med. 2011 Apr 1;50(7):866-73. doi: 10.1016/j.freeradbiomed.2010.12.030. Epub 2011 Jan 6.

48.

Insulin-like signaling determines survival during stress via posttranscriptional mechanisms in C. elegans.

McColl G, Rogers AN, Alavez S, Hubbard AE, Melov S, Link CD, Bush AI, Kapahi P, Lithgow GJ.

Cell Metab. 2010 Sep 8;12(3):260-72. doi: 10.1016/j.cmet.2010.08.004.

49.

Eccentric exercise activates novel transcriptional regulation of hypertrophic signaling pathways not affected by hormone changes.

MacNeil LG, Melov S, Hubbard AE, Baker SK, Tarnopolsky MA.

PLoS One. 2010 May 18;5(5):e10695. doi: 10.1371/journal.pone.0010695.

50.

Limb immobilization induces a coordinate down-regulation of mitochondrial and other metabolic pathways in men and women.

Abadi A, Glover EI, Isfort RJ, Raha S, Safdar A, Yasuda N, Kaczor JJ, Melov S, Hubbard A, Qu X, Phillips SM, Tarnopolsky M.

PLoS One. 2009 Aug 5;4(8):e6518. doi: 10.1371/journal.pone.0006518.

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