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Items: 32

1.

Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes.

Axelsson AS, Tubbs E, Mecham B, Chacko S, Nenonen HA, Tang Y, Fahey JW, Derry JMJ, Wollheim CB, Wierup N, Haymond MW, Friend SH, Mulder H, Rosengren AH.

Sci Transl Med. 2017 Jun 14;9(394). pii: eaah4477. doi: 10.1126/scitranslmed.aah4477.

PMID:
28615356
2.

Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes.

Axelsson AS, Mahdi T, Nenonen HA, Singh T, Hänzelmann S, Wendt A, Bagge A, Reinbothe TM, Millstein J, Yang X, Zhang B, Gusmao EG, Shu L, Szabat M, Tang Y, Wang J, Salö S, Eliasson L, Artner I, Fex M, Johnson JD, Wollheim CB, Derry JMJ, Mecham B, Spégel P, Mulder H, Costa IG, Zhang E, Rosengren AH.

Nat Commun. 2017 Jun 6;8:15652. doi: 10.1038/ncomms15652.

3.

Corrigendum: Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability.

Evrard SM, Lecce L, Michelis KC, Nomura-Kitabayashi A, Pandey G, Purushothaman KR, d'Escamard V, Li JR, Hadri L, Fujitani K, Moreno PR, Benard L, Rimmele P, Cohain A, Mecham B, Randolph GJ, Nabel EG, Hajjar R, Fuster V, Boehm M, Kovacic JC.

Nat Commun. 2017 Feb 16;8:14710. doi: 10.1038/ncomms14710. No abstract available.

4.

Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability.

Evrard SM, Lecce L, Michelis KC, Nomura-Kitabayashi A, Pandey G, Purushothaman KR, d'Escamard V, Li JR, Hadri L, Fujitani K, Moreno PR, Benard L, Rimmele P, Cohain A, Mecham B, Randolph GJ, Nabel EG, Hajjar R, Fuster V, Boehm M, Kovacic JC.

Nat Commun. 2016 Jun 24;7:11853. doi: 10.1038/ncomms11853.

5.

A Distributed Network for Intensive Longitudinal Monitoring in Metastatic Triple-Negative Breast Cancer.

Blau CA, Ramirez AB, Blau S, Pritchard CC, Dorschner MO, Schmechel SC, Martins TJ, Mahen EM, Burton KA, Komashko VM, Radenbaugh AJ, Dougherty K, Thomas A, Miller CP, Annis J, Fromm JR, Song C, Chang E, Howard K, Austin S, Schmidt RA, Linenberger ML, Becker PS, Senecal FM, Mecham BH, Lee SI, Madan A, Ronen R, Dutkowski J, Heimfeld S, Wood BL, Stilwell JL, Kaldjian EP, Haussler D, Zhu J.

J Natl Compr Canc Netw. 2016 Jan;14(1):8-17.

6.

Transcriptional analysis of human cranial compartments with different embryonic origins.

Homayounfar N, Park SS, Afsharinejad Z, Bammler TK, MacDonald JW, Farin FM, Mecham BH, Cunningham ML.

Arch Oral Biol. 2015 Sep;60(9):1450-60. doi: 10.1016/j.archoralbio.2015.06.008. Epub 2015 Jul 2.

7.

Osteoblast differentiation profiles define sex specific gene expression patterns in craniosynostosis.

Park SS, Beyer RP, Smyth MD, Clarke CM, Timms AE, Bammler TK, Stamper BD, Mecham BH, Gustafson JA, Cunningham ML.

Bone. 2015 Jul;76:169-76. doi: 10.1016/j.bone.2015.03.001. Epub 2015 Mar 7.

8.

Exome sequencing identifies a recurrent de novo ZSWIM6 mutation associated with acromelic frontonasal dysostosis.

Smith JD, Hing AV, Clarke CM, Johnson NM, Perez FA, Park SS, Horst JA, Mecham B, Maves L, Nickerson DA; University of Washington Center for Mendelian Genomics, Cunningham ML.

Am J Hum Genet. 2014 Aug 7;95(2):235-40. doi: 10.1016/j.ajhg.2014.07.008.

9.

Biodynamics of hallux abductovalgus etiology and preoperative evaluation.

Burns PR, Mecham B.

Clin Podiatr Med Surg. 2014 Apr;31(2):197-212. doi: 10.1016/j.cpm.2013.12.002. Epub 2014 Feb 21. Review.

PMID:
24685187
10.

Derivation of naive human embryonic stem cells.

Ware CB, Nelson AM, Mecham B, Hesson J, Zhou W, Jonlin EC, Jimenez-Caliani AJ, Deng X, Cavanaugh C, Cook S, Tesar PJ, Okada J, Margaretha L, Sperber H, Choi M, Blau CA, Treuting PM, Hawkins RD, Cirulli V, Ruohola-Baker H.

Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4484-9. doi: 10.1073/pnas.1319738111. Epub 2014 Mar 12.

11.

MyoD is a tumor suppressor gene in medulloblastoma.

Dey J, Dubuc AM, Pedro KD, Thirstrup D, Mecham B, Northcott PA, Wu X, Shih D, Tapscott SJ, LeBlanc M, Taylor MD, Olson JM.

Cancer Res. 2013 Nov 15;73(22):6828-37. doi: 10.1158/0008-5472.CAN-13-0730-T. Epub 2013 Oct 3.

12.

A statin-dependent QTL for GATM expression is associated with statin-induced myopathy.

Mangravite LM, Engelhardt BE, Medina MW, Smith JD, Brown CD, Chasman DI, Mecham BH, Howie B, Shim H, Naidoo D, Feng Q, Rieder MJ, Chen YD, Rotter JI, Ridker PM, Hopewell JC, Parish S, Armitage J, Collins R, Wilke RA, Nickerson DA, Stephens M, Krauss RM.

Nature. 2013 Oct 17;502(7471):377-80. doi: 10.1038/nature12508. Epub 2013 Aug 28.

13.

Improving breast cancer survival analysis through competition-based multidimensional modeling.

Bilal E, Dutkowski J, Guinney J, Jang IS, Logsdon BA, Pandey G, Sauerwine BA, Shimoni Y, Moen Vollan HK, Mecham BH, Rueda OM, Tost J, Curtis C, Alvarez MJ, Kristensen VN, Aparicio S, Børresen-Dale AL, Caldas C, Califano A, Friend SH, Ideker T, Schadt EE, Stolovitzky GA, Margolin AA.

PLoS Comput Biol. 2013;9(5):e1003047. doi: 10.1371/journal.pcbi.1003047. Epub 2013 May 9.

14.

Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer.

Margolin AA, Bilal E, Huang E, Norman TC, Ottestad L, Mecham BH, Sauerwine B, Kellen MR, Mangravite LM, Furia MD, Vollan HK, Rueda OM, Guinney J, Deflaux NA, Hoff B, Schildwachter X, Russnes HG, Park D, Vang VO, Pirtle T, Youseff L, Citro C, Curtis C, Kristensen VN, Hellerstein J, Friend SH, Stolovitzky G, Aparicio S, Caldas C, Børresen-Dale AL.

Sci Transl Med. 2013 Apr 17;5(181):181re1. doi: 10.1126/scitranslmed.3006112.

15.

PPP2R2C loss promotes castration-resistance and is associated with increased prostate cancer-specific mortality.

Bluemn EG, Spencer ES, Mecham B, Gordon RR, Coleman I, Lewinshtein D, Mostaghel E, Zhang X, Annis J, Grandori C, Porter C, Nelson PS.

Mol Cancer Res. 2013 Jun;11(6):568-78. doi: 10.1158/1541-7786.MCR-12-0710. Epub 2013 Mar 14.

16.

Transcriptome correlation analysis identifies two unique craniosynostosis subtypes associated with IRS1 activation.

Stamper BD, Mecham B, Park SS, Wilkerson H, Farin FM, Beyer RP, Bammler TK, Mangravite LM, Cunningham ML.

Physiol Genomics. 2012 Dec 1;44(23):1154-63. doi: 10.1152/physiolgenomics.00085.2012. Epub 2012 Oct 16.

17.

A distinct Smoothened mutation causes severe cerebellar developmental defects and medulloblastoma in a novel transgenic mouse model.

Dey J, Ditzler S, Knoblaugh SE, Hatton BA, Schelter JM, Cleary MA, Mecham B, Rorke-Adams LB, Olson JM.

Mol Cell Biol. 2012 Oct;32(20):4104-15. Epub 2012 Aug 6.

18.

Differential expression of extracellular matrix-mediated pathways in single-suture craniosynostosis.

Stamper BD, Park SS, Beyer RP, Bammler TK, Farin FM, Mecham B, Cunningham ML.

PLoS One. 2011;6(10):e26557. doi: 10.1371/journal.pone.0026557. Epub 2011 Oct 19.

19.

Supervised normalization of microarrays.

Mecham BH, Nelson PS, Storey JD.

Bioinformatics. 2010 May 15;26(10):1308-15. doi: 10.1093/bioinformatics/btq118. Epub 2010 Mar 31.

20.

Histone deacetylase inhibition elicits an evolutionarily conserved self-renewal program in embryonic stem cells.

Ware CB, Wang L, Mecham BH, Shen L, Nelson AM, Bar M, Lamba DA, Dauphin DS, Buckingham B, Askari B, Lim R, Tewari M, Gartler SM, Issa JP, Pavlidis P, Duan Z, Blau CA.

Cell Stem Cell. 2009 Apr 3;4(4):359-69. doi: 10.1016/j.stem.2009.03.001.

21.

Conserved gene expression programs integrate mammalian prostate development and tumorigenesis.

Pritchard C, Mecham B, Dumpit R, Coleman I, Bhattacharjee M, Chen Q, Sikes RA, Nelson PS.

Cancer Res. 2009 Mar 1;69(5):1739-47. doi: 10.1158/0008-5472.CAN-07-6817. Epub 2009 Feb 17.

22.

Expression profiles of the mouse lung identify a molecular signature of time-to-birth.

Kho AT, Bhattacharya S, Mecham BH, Hong J, Kohane IS, Mariani TJ.

Am J Respir Cell Mol Biol. 2009 Jan;40(1):47-57. doi: 10.1165/rcmb.2008-0048OC. Epub 2008 Jul 29.

23.

Individual matrix metalloproteinases control distinct transcriptional responses in airway epithelial cells infected with Pseudomonas aeruginosa.

Kassim SY, Gharib SA, Mecham BH, Birkland TP, Parks WC, McGuire JK.

Infect Immun. 2007 Dec;75(12):5640-50. Epub 2007 Oct 8.

24.

Genetic background influences murine prostate gene expression: implications for cancer phenotypes.

Bianchi-Frias D, Pritchard C, Mecham BH, Coleman IM, Nelson PS.

Genome Biol. 2007;8(6):R117.

25.

Induction of the plasminogen activator system by mechanical stimulation of human bronchial epithelial cells.

Chu EK, Cheng J, Foley JS, Mecham BH, Owen CA, Haley KJ, Mariani TJ, Kohane IS, Tschumperlin DJ, Drazen JM.

Am J Respir Cell Mol Biol. 2006 Dec;35(6):628-38. Epub 2006 Jun 22.

26.

The SERPINE2 gene is associated with chronic obstructive pulmonary disease.

Demeo DL, Mariani TJ, Lange C, Srisuma S, Litonjua AA, Celedon JC, Lake SL, Reilly JJ, Chapman HA, Mecham BH, Haley KJ, Sylvia JS, Sparrow D, Spira AE, Beane J, Pinto-Plata V, Speizer FE, Shapiro SD, Weiss ST, Silverman EK.

Am J Hum Genet. 2006 Feb;78(2):253-64. Epub 2005 Dec 15.

28.

Increased measurement accuracy for sequence-verified microarray probes.

Mecham BH, Wetmore DZ, Szallasi Z, Sadovsky Y, Kohane I, Mariani TJ.

Physiol Genomics. 2004 Aug 11;18(3):308-15.

PMID:
15161964
29.

Sequence-matched probes produce increased cross-platform consistency and more reproducible biological results in microarray-based gene expression measurements.

Mecham BH, Klus GT, Strovel J, Augustus M, Byrne D, Bozso P, Wetmore DZ, Mariani TJ, Kohane IS, Szallasi Z.

Nucleic Acids Res. 2004 May 25;32(9):e74.

30.

Long-term effects of clipping and nitrogen management in turfgrass on soil organic carbon and nitrogen dynamics: the CENTURY model simulation.

Qian YL, Bandaranayake W, Parton WJ, Mecham B, Harivandi MA, Mosier AR.

J Environ Qual. 2003 Sep-Oct;32(5):1694-700.

PMID:
14535310
31.

A variable fold change threshold determines significance for expression microarrays.

Mariani TJ, Budhraja V, Mecham BH, Gu CC, Watson MA, Sadovsky Y.

FASEB J. 2003 Feb;17(2):321-3. Epub 2002 Dec 3.

PMID:
12475896
32.

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