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Items: 1 to 50 of 234

1.

The Effects of Endocrine Disruptors on Adipogenesis and Osteogenesis in Mesenchymal Stem Cells: A Review.

Bateman ME, Strong AL, McLachlan JA, Burow ME, Bunnell BA.

Front Endocrinol (Lausanne). 2017 Jan 9;7:171. doi: 10.3389/fendo.2016.00171. eCollection 2016. Review.

2.

Minireview: Endocrine Disruptors: Past Lessons and Future Directions.

Schug TT, Johnson AF, Birnbaum LS, Colborn T, Guillette LJ Jr, Crews DP, Collins T, Soto AM, Vom Saal FS, McLachlan JA, Sonnenschein C, Heindel JJ.

Mol Endocrinol. 2016 Aug;30(8):833-47. doi: 10.1210/me.2016-1096. Epub 2016 Jul 19. Review.

3.

Environmental signaling: from environmental estrogens to endocrine-disrupting chemicals and beyond.

McLachlan JA.

Andrology. 2016 Jul;4(4):684-94. doi: 10.1111/andr.12206. Epub 2016 May 27. Review.

4.

Glyceollin, a novel regulator of mTOR/p70S6 in estrogen receptor positive breast cancer.

Bratton MR, Martin EC, Elliott S, Rhodes LV, Collins-Burow BM, McLachlan JA, Wiese TE, Boue SM, Burow ME.

J Steroid Biochem Mol Biol. 2015 Jun;150:17-23. doi: 10.1016/j.jsbmb.2014.12.014. Epub 2015 Mar 12.

5.

Bisphenol A enhances adipogenic differentiation of human adipose stromal/stem cells.

Ohlstein JF, Strong AL, McLachlan JA, Gimble JM, Burow ME, Bunnell BA.

J Mol Endocrinol. 2014 Dec;53(3):345-53. doi: 10.1530/JME-14-0052. Epub 2014 Aug 20.

6.

Effects of the endocrine-disrupting chemical DDT on self-renewal and differentiation of human mesenchymal stem cells.

Strong AL, Shi Z, Strong MJ, Miller DF, Rusch DB, Buechlein AM, Flemington EK, McLachlan JA, Nephew KP, Burow ME, Bunnell BA.

Environ Health Perspect. 2015 Jan;123(1):42-8. doi: 10.1289/ehp.1408188. Epub 2014 Jul 11.

7.

In vitro and in vivo evaluation of novel anticancer agents in triple negative breast cancer models.

Johnson KP, Yearby LA, Stoute D, Burow ME, Rhodes LV, Gray M, Carriere P, Tilghman SL, McLachlan JA, Ochieng J.

J Health Care Poor Underserved. 2013 Feb;24(1 Suppl):104-11. doi: 10.1353/hpu.2013.0047.

8.

Phytoalexins, miRNAs and breast cancer: a review of phytochemical-mediated miRNA regulation in breast cancer.

Tilghman SL, Rhodes LV, Bratton MR, Carriere P, Preyan LC, Boue SM, Vasaitis TS, McLachlan JA, Burow ME.

J Health Care Poor Underserved. 2013 Feb;24(1 Suppl):36-46. doi: 10.1353/hpu.2013.0036. Review.

9.

Pharmacology and anti-tumor activity of RWJ67657, a novel inhibitor of p38 mitogen activated protein kinase.

Antoon JW, Bratton MR, Guillot LM, Wadsworth S, Salvo VA, Elliott S, McLachlan JA, Burow ME.

Am J Cancer Res. 2012;2(4):446-58. Epub 2012 Jun 28.

10.

Antiestrogenic activity of flavonoid phytochemicals mediated via the c-Jun N-terminal protein kinase pathway. Cell-type specific regulation of estrogen receptor alpha.

Collins-Burow BM, Antoon JW, Frigo DE, Elliott S, Weldon CB, Boue SM, Beckman BS, Curiel TJ, Alam J, McLachlan JA, Burow ME.

J Steroid Biochem Mol Biol. 2012 Oct;132(1-2):186-93. doi: 10.1016/j.jsbmb.2012.05.004. Epub 2012 May 24.

11.

The organochlorine o,p'-DDT plays a role in coactivator-mediated MAPK crosstalk in MCF-7 breast cancer cells.

Bratton MR, Frigo DE, Segar HC, Nephew KP, McLachlan JA, Wiese TE, Burow ME.

Environ Health Perspect. 2012 Sep;120(9):1291-6. doi: 10.1289/ehp.1104296. Epub 2012 May 18.

12.

Gαo potentiates estrogen receptor α activity via the ERK signaling pathway.

Bratton MR, Antoon JW, Duong BN, Frigo DE, Tilghman S, Collins-Burow BM, Elliott S, Tang Y, Melnik LI, Lai L, Alam J, Beckman BS, Hill SM, Rowan BG, McLachlan JA, Burow ME.

J Endocrinol. 2012 Jul;214(1):45-54. doi: 10.1530/JOE-12-0097. Epub 2012 May 4.

13.

Endocrine disruptor regulation of microRNA expression in breast carcinoma cells.

Tilghman SL, Bratton MR, Segar HC, Martin EC, Rhodes LV, Li M, McLachlan JA, Wiese TE, Nephew KP, Burow ME.

PLoS One. 2012;7(3):e32754. doi: 10.1371/journal.pone.0032754. Epub 2012 Mar 5.

14.

Environmental signaling and reproduction: a comparative biological and chemical perspective.

McLachlan JA, Tilghman SL, Burow ME, Bratton MR.

Mol Cell Endocrinol. 2012 May 6;354(1-2):60-2. doi: 10.1016/j.mce.2011.11.028. Epub 2011 Dec 8. Review.

15.

Estrogenic and antiestrogenic activities of phytoalexins from red kidney bean (Phaseolus vulgaris L.).

Boué SM, Burow ME, Wiese TE, Shih BY, Elliott S, Carter-Wientjes CH, McLachlan JA, Bhatnagar D.

J Agric Food Chem. 2011 Jan 12;59(1):112-20. doi: 10.1021/jf102255u. Epub 2010 Dec 6.

PMID:
21133423
16.

Effects of 7-O substitutions on estrogenic and anti-estrogenic activities of daidzein analogues in MCF-7 breast cancer cells.

Jiang Q, Payton-Stewart F, Elliott S, Driver J, Rhodes LV, Zhang Q, Zheng S, Bhatnagar D, Boue SM, Collins-Burow BM, Sridhar J, Stevens C, McLachlan JA, Wiese TE, Burow ME, Wang G.

J Med Chem. 2010 Aug 26;53(16):6153-63. doi: 10.1021/jm100610w.

17.

Regulation of ERalpha-mediated transcription of Bcl-2 by PI3K-AKT crosstalk: implications for breast cancer cell survival.

Bratton MR, Duong BN, Elliott S, Weldon CB, Beckman BS, McLachlan JA, Burow ME.

Int J Oncol. 2010 Sep;37(3):541-50.

18.

Glyceollin I enantiomers distinctly regulate ER-mediated gene expression.

Payton-Stewart F, Khupse RS, Boué SM, Elliott S, Zimmermann MC, Skripnikova EV, Ashe H, Tilghman SL, Beckman BS, Cleveland TE, McLachlan JA, Bhatnagar D, Wiese TE, Erhardt P, Burow ME.

Steroids. 2010 Dec;75(12):870-8. doi: 10.1016/j.steroids.2010.05.007. Epub 2010 May 21.

PMID:
20493896
19.

Environmental hormones: Multiple pathways for response may lead to multiple disease outcomes.

Tilghman SL, Nierth-Simpson EN, Wallace R, Burow ME, McLachlan JA.

Steroids. 2010 Aug-Sep;75(8-9):520-3. doi: 10.1016/j.steroids.2010.05.004. Epub 2010 May 11. Review.

PMID:
20466011
20.

Glyceollin I, a novel antiestrogenic phytoalexin isolated from activated soy.

Zimmermann MC, Tilghman SL, Boué SM, Salvo VA, Elliott S, Williams KY, Skripnikova EV, Ashe H, Payton-Stewart F, Vanhoy-Rhodes L, Fonseca JP, Corbitt C, Collins-Burow BM, Howell MH, Lacey M, Shih BY, Carter-Wientjes C, Cleveland TE, McLachlan JA, Wiese TE, Beckman BS, Burow ME.

J Pharmacol Exp Ther. 2010 Jan;332(1):35-45. doi: 10.1124/jpet.109.160382. Epub 2009 Oct 1.

21.

Adult human mesenchymal stem cells enhance breast tumorigenesis and promote hormone independence.

Rhodes LV, Muir SE, Elliott S, Guillot LM, Antoon JW, Penfornis P, Tilghman SL, Salvo VA, Fonseca JP, Lacey MR, Beckman BS, McLachlan JA, Rowan BG, Pochampally R, Burow ME.

Breast Cancer Res Treat. 2010 Jun;121(2):293-300. doi: 10.1007/s10549-009-0458-2. Epub 2009 Jul 12.

22.

Why public health agencies cannot depend on good laboratory practices as a criterion for selecting data: the case of bisphenol A.

Myers JP, vom Saal FS, Akingbemi BT, Arizono K, Belcher S, Colborn T, Chahoud I, Crain DA, Farabollini F, Guillette LJ Jr, Hassold T, Ho SM, Hunt PA, Iguchi T, Jobling S, Kanno J, Laufer H, Marcus M, McLachlan JA, Nadal A, Oehlmann J, Olea N, Palanza P, Parmigiani S, Rubin BS, Schoenfelder G, Sonnenschein C, Soto AM, Talsness CE, Taylor JA, Vandenberg LN, Vandenbergh JG, Vogel S, Watson CS, Welshons WV, Zoeller RT.

Environ Health Perspect. 2009 Mar;117(3):309-15. doi: 10.1289/ehp.0800173. Epub 2008 Oct 22.

23.

Human uterine smooth muscle and leiomyoma cells differ in their rapid 17beta-estradiol signaling: implications for proliferation.

Nierth-Simpson EN, Martin MM, Chiang TC, Melnik LI, Rhodes LV, Muir SE, Burow ME, McLachlan JA.

Endocrinology. 2009 May;150(5):2436-45. doi: 10.1210/en.2008-0224. Epub 2009 Jan 29.

24.

Identification of the potent phytoestrogen glycinol in elicited soybean (Glycine max).

Boué SM, Tilghman SL, Elliott S, Zimmerman MC, Williams KY, Payton-Stewart F, Miraflor AP, Howell MH, Shih BY, Carter-Wientjes CH, Segar C, Beckman BS, Wiese TE, Cleveland TE, McLachlan JA, Burow ME.

Endocrinology. 2009 May;150(5):2446-53. doi: 10.1210/en.2008-1235. Epub 2008 Dec 30.

25.

Proteomic analysis of tumor necrosis factor-alpha resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype.

Zhou C, Nitschke AM, Xiong W, Zhang Q, Tang Y, Bloch M, Elliott S, Zhu Y, Bazzone L, Yu D, Weldon CB, Schiff R, McLachlan JA, Beckman BS, Wiese TE, Nephew KP, Shan B, Burow ME, Wang G.

Breast Cancer Res. 2008;10(6):R105. doi: 10.1186/bcr2210. Epub 2008 Dec 16.

26.

Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing.

Crain DA, Janssen SJ, Edwards TM, Heindel J, Ho SM, Hunt P, Iguchi T, Juul A, McLachlan JA, Schwartz J, Skakkebaek N, Soto AM, Swan S, Walker C, Woodruff TK, Woodruff TJ, Giudice LC, Guillette LJ Jr.

Fertil Steril. 2008 Oct;90(4):911-40. doi: 10.1016/j.fertnstert.2008.08.067. Review.

27.

Organochlorine-mediated potentiation of the general coactivator p300 through p38 mitogen-activated protein kinase.

Bratton MR, Frigo DE, Vigh-Conrad KA, Fan D, Wadsworth S, McLachlan JA, Burow ME.

Carcinogenesis. 2009 Jan;30(1):106-13. doi: 10.1093/carcin/bgn213. Epub 2008 Sep 12.

28.

Detecting ligands and dissecting nuclear receptor-signaling pathways using recombinant strains of the yeast Saccharomyces cerevisiae.

Fox JE, Burow ME, McLachlan JA, Miller CA 3rd.

Nat Protoc. 2008;3(4):637-45. doi: 10.1038/nprot.2008.33.

PMID:
18388946
29.

Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure.

vom Saal FS, Akingbemi BT, Belcher SM, Birnbaum LS, Crain DA, Eriksen M, Farabollini F, Guillette LJ Jr, Hauser R, Heindel JJ, Ho SM, Hunt PA, Iguchi T, Jobling S, Kanno J, Keri RA, Knudsen KE, Laufer H, LeBlanc GA, Marcus M, McLachlan JA, Myers JP, Nadal A, Newbold RR, Olea N, Prins GS, Richter CA, Rubin BS, Sonnenschein C, Soto AM, Talsness CE, Vandenbergh JG, Vandenberg LN, Walser-Kuntz DR, Watson CS, Welshons WV, Wetherill Y, Zoeller RT.

Reprod Toxicol. 2007 Aug-Sep;24(2):131-8. Epub 2007 Jul 27. No abstract available.

30.

In vitro molecular mechanisms of bisphenol A action.

Wetherill YB, Akingbemi BT, Kanno J, McLachlan JA, Nadal A, Sonnenschein C, Watson CS, Zoeller RT, Belcher SM.

Reprod Toxicol. 2007 Aug-Sep;24(2):178-98. Epub 2007 May 29. Review.

PMID:
17628395
31.

Pesticides reduce symbiotic efficiency of nitrogen-fixing rhizobia and host plants.

Fox JE, Gulledge J, Engelhaupt E, Burow ME, McLachlan JA.

Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10282-7. Epub 2007 Jun 4.

32.

Antiestrogenic glyceollins suppress human breast and ovarian carcinoma tumorigenesis.

Salvo VA, Boué SM, Fonseca JP, Elliott S, Corbitt C, Collins-Burow BM, Curiel TJ, Srivastav SK, Shih BY, Carter-Wientjes C, Wood CE, Erhardt PW, Beckman BS, McLachlan JA, Cleveland TE, Burow ME.

Clin Cancer Res. 2006 Dec 1;12(23):7159-64.

33.

AKT regulation of estrogen receptor beta transcriptional activity in breast cancer.

Duong BN, Elliott S, Frigo DE, Melnik LI, Vanhoy L, Tomchuck S, Lebeau HP, David O, Beckman BS, Alam J, Bratton MR, McLachlan JA, Burow ME.

Cancer Res. 2006 Sep 1;66(17):8373-81.

34.

Commentary: prenatal exposure to diethylstilbestrol (DES): a continuing story.

McLachlan JA.

Int J Epidemiol. 2006 Aug;35(4):868-70. Epub 2006 Jul 17. No abstract available.

PMID:
16847027
35.

Epigenetics, evolution, endocrine disruption, health, and disease.

Crews D, McLachlan JA.

Endocrinology. 2006 Jun;147(6 Suppl):S4-10. Epub 2006 May 11. Review.

PMID:
16690812
36.

Endocrine disrupters and female reproductive health.

McLachlan JA, Simpson E, Martin M.

Best Pract Res Clin Endocrinol Metab. 2006 Mar;20(1):63-75. Review.

PMID:
16522520
37.

p38 mitogen-activated protein kinase stimulates estrogen-mediated transcription and proliferation through the phosphorylation and potentiation of the p160 coactivator glucocorticoid receptor-interacting protein 1.

Frigo DE, Basu A, Nierth-Simpson EN, Weldon CB, Dugan CM, Elliott S, Collins-Burow BM, Salvo VA, Zhu Y, Melnik LI, Lopez GN, Kushner PJ, Curiel TJ, Rowan BG, McLachlan JA, Burow ME.

Mol Endocrinol. 2006 May;20(5):971-83. Epub 2006 Jan 12.

PMID:
16410316
38.

PKC-mediated survival signaling in breast carcinoma cells: a role for MEK1-AP1 signaling.

Weldon CB, McKee A, Collins-Burow BM, Melnik LI, Scandurro AB, McLachlan JA, Burow ME, Beckman BS.

Int J Oncol. 2005 Mar;26(3):763-8.

PMID:
15703835
39.

Xenobiotic-induced TNF-alpha expression and apoptosis through the p38 MAPK signaling pathway.

Frigo DE, Vigh KA, Struckhoff AP, Elliott S, Beckman BS, Burow ME, McLachlan JA.

Toxicol Lett. 2005 Feb 15;155(2):227-38.

PMID:
15603917
40.

Developmental diethylstilbestrol exposure alters genetic pathways of uterine cytodifferentiation.

Huang WW, Yin Y, Bi Q, Chiang TC, Garner N, Vuoristo J, McLachlan JA, Ma L.

Mol Endocrinol. 2005 Mar;19(3):669-82. Epub 2004 Dec 9.

PMID:
15591538
41.

Phytoestrogen signaling and symbiotic gene activation are disrupted by endocrine-disrupting chemicals.

Fox JE, Starcevic M, Jones PE, Burow ME, McLachlan JA.

Environ Health Perspect. 2004 May;112(6):672-7.

42.

Mechanism of AP-1-mediated gene expression by select organochlorines through the p38 MAPK pathway.

Frigo DE, Tang Y, Beckman BS, Scandurro AB, Alam J, Burow ME, McLachlan JA.

Carcinogenesis. 2004 Feb;25(2):249-61. Epub 2003 Nov 6.

PMID:
14604893
43.

Neonatal diethylstilbestrol exposure induces persistent elevation of c-fos expression and hypomethylation in its exon-4 in mouse uterus.

Li S, Hansman R, Newbold R, Davis B, McLachlan JA, Barrett JC.

Mol Carcinog. 2003 Oct;38(2):78-84.

PMID:
14502647
44.

DNA hypomethylation and imbalanced expression of DNA methyltransferases (DNMT1, 3A, and 3B) in human uterine leiomyoma.

Li S, Chiang TC, Richard-Davis G, Barrett JC, Mclachlan JA.

Gynecol Oncol. 2003 Jul;90(1):123-30.

PMID:
12821352
45.

Symbiotic gene activation is interrupted by endocrine disrupting chemicals.

Fox JE, Burow ME, McLachlan JA.

ScientificWorldJournal. 2001 Nov 13;1:653-5. Review.

46.

Environmental exposure, DNA methylation, and gene regulation: lessons from diethylstilbesterol-induced cancers.

Li S, Hursting SD, Davis BJ, McLachlan JA, Barrett JC.

Ann N Y Acad Sci. 2003 Mar;983:161-9. Review.

PMID:
12724221
47.

Evaluation of the estrogenic effects of legume extracts containing phytoestrogens.

Boué SM, Wiese TE, Nehls S, Burow ME, Elliott S, Carter-Wientjes CH, Shih BY, McLachlan JA, Cleveland TE.

J Agric Food Chem. 2003 Apr 9;51(8):2193-9.

PMID:
12670155
48.

Affinity of the alligator estrogen receptor for serum pesticide contaminants.

Guillette LJ Jr, Vonier PM, McLachlan JA.

Toxicology. 2002 Dec 27;181-182:151-4.

PMID:
12505301
49.

DDT and its metabolites alter gene expression in human uterine cell lines through estrogen receptor-independent mechanisms.

Frigo DE, Burow ME, Mitchell KA, Chiang TC, McLachlan JA.

Environ Health Perspect. 2002 Dec;110(12):1239-45.

50.

Identification of mitogen-activated protein kinase kinase as a chemoresistant pathway in MCF-7 cells by using gene expression microarray.

Weldon CB, Scandurro AB, Rolfe KW, Clayton JL, Elliott S, Butler NN, Melnik LI, Alam J, McLachlan JA, Jaffe BM, Beckman BS, Burow ME.

Surgery. 2002 Aug;132(2):293-301.

PMID:
12219026

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