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Items: 18

1.

Inhibition of androgen receptor by decoy molecules delays progression to castration-recurrent prostate cancer.

Myung JK, Wang G, Chiu HH, Wang J, Mawji NR, Sadar MD.

PLoS One. 2017 Mar 17;12(3):e0174134. doi: 10.1371/journal.pone.0174134. eCollection 2017.

2.

Sintokamide A Is a Novel Antagonist of Androgen Receptor That Uniquely Binds Activation Function-1 in Its Amino-terminal Domain.

Banuelos CA, Tavakoli I, Tien AH, Caley DP, Mawji NR, Li Z, Wang J, Yang YC, Imamura Y, Yan L, Wen JG, Andersen RJ, Sadar MD.

J Biol Chem. 2016 Oct 14;291(42):22231-22243. Epub 2016 Aug 30.

3.

An imaging agent to detect androgen receptor and its active splice variants in prostate cancer.

Imamura Y, Tien AH, Pan J, Leung JK, Banuelos CA, Jian K, Wang J, Mawji NR, Fernandez JG, Lin KS, Andersen RJ, Sadar MD.

JCI Insight. 2016 Jul 21;1(11). pii: e87850.

4.

Targeting Androgen Receptor Activation Function-1 with EPI to Overcome Resistance Mechanisms in Castration-Resistant Prostate Cancer.

Yang YC, Banuelos CA, Mawji NR, Wang J, Kato M, Haile S, McEwan IJ, Plymate S, Sadar MD.

Clin Cancer Res. 2016 Sep 1;22(17):4466-77. doi: 10.1158/1078-0432.CCR-15-2901. Epub 2016 May 2.

5.

Cotargeting Androgen Receptor Splice Variants and mTOR Signaling Pathway for the Treatment of Castration-Resistant Prostate Cancer.

Kato M, Banuelos CA, Imamura Y, Leung JK, Caley DP, Wang J, Mawji NR, Sadar MD.

Clin Cancer Res. 2016 Jun 1;22(11):2744-54. doi: 10.1158/1078-0432.CCR-15-2119. Epub 2015 Dec 28.

6.

Characterization of niphatenones that inhibit androgen receptor N-terminal domain.

Banuelos CA, Lal A, Tien AH, Shah N, Yang YC, Mawji NR, Meimetis LG, Park J, Kunzhong J, Andersen RJ, Sadar MD.

PLoS One. 2014 Sep 30;9(9):e107991. doi: 10.1371/journal.pone.0107991. eCollection 2014.

7.

An androgen receptor N-terminal domain antagonist for treating prostate cancer.

Myung JK, Banuelos CA, Fernandez JG, Mawji NR, Wang J, Tien AH, Yang YC, Tavakoli I, Haile S, Watt K, McEwan IJ, Plymate S, Andersen RJ, Sadar MD.

J Clin Invest. 2013 Jul;123(7):2948-60. doi: 10.1172/JCI66398. Epub 2013 Jun 3.

8.

Spongian diterpenoids inhibit androgen receptor activity.

Yang YC, Meimetis LG, Tien AH, Mawji NR, Carr G, Wang J, Andersen RJ, Sadar MD.

Mol Cancer Ther. 2013 May;12(5):621-31. doi: 10.1158/1535-7163.MCT-12-0978. Epub 2013 Feb 26.

9.

Niphatenones, glycerol ethers from the sponge Niphates digitalis block androgen receptor transcriptional activity in prostate cancer cells: structure elucidation, synthesis, and biological activity.

Meimetis LG, Williams DE, Mawji NR, Banuelos CA, Lal AA, Park JJ, Tien AH, Fernandez JG, de Voogd NJ, Sadar MD, Andersen RJ.

J Med Chem. 2012 Jan 12;55(1):503-14. doi: 10.1021/jm2014056. Epub 2011 Dec 28.

PMID:
22148427
10.

Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor.

Andersen RJ, Mawji NR, Wang J, Wang G, Haile S, Myung JK, Watt K, Tam T, Yang YC, BaƱuelos CA, Williams DE, McEwan IJ, Wang Y, Sadar MD.

Cancer Cell. 2010 Jun 15;17(6):535-46. doi: 10.1016/j.ccr.2010.04.027.

11.

Sintokamides A to E, chlorinated peptides from the sponge Dysidea sp. that inhibit transactivation of the N-terminus of the androgen receptor in prostate cancer cells.

Sadar MD, Williams DE, Mawji NR, Patrick BO, Wikanta T, Chasanah E, Irianto HE, Soest RV, Andersen RJ.

Org Lett. 2008 Nov 6;10(21):4947-50. doi: 10.1021/ol802021w. Epub 2008 Oct 4.

PMID:
18834139
12.

Androgen receptor decoy molecules block the growth of prostate cancer.

Quayle SN, Mawji NR, Wang J, Sadar MD.

Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1331-6. Epub 2007 Jan 16.

13.

An orthotopic metastatic prostate cancer model in SCID mice via grafting of a transplantable human prostate tumor line.

Wang Y, Xue H, Cutz JC, Bayani J, Mawji NR, Chen WG, Goetz LJ, Hayward SW, Sadar MD, Gilks CB, Gout PW, Squire JA, Cunha GR, Wang YZ.

Lab Invest. 2005 Nov;85(11):1392-404.

14.

Osteoblast-derived factors induce androgen-independent proliferation and expression of prostate-specific antigen in human prostate cancer cells.

Blaszczyk N, Masri BA, Mawji NR, Ueda T, McAlinden G, Duncan CP, Bruchovsky N, Schweikert HU, Schnabel D, Jones EC, Sadar MD.

Clin Cancer Res. 2004 Mar 1;10(5):1860-9.

15.

Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells.

Ueda T, Mawji NR, Bruchovsky N, Sadar MD.

J Biol Chem. 2002 Oct 11;277(41):38087-94. Epub 2002 Aug 5.

16.

Differential transactivation by the androgen receptor in prostate cancer cells.

Snoek R, Bruchovsky N, Kasper S, Matusik RJ, Gleave M, Sato N, Mawji NR, Rennie PS.

Prostate. 1998 Sep 1;36(4):256-63.

PMID:
9719026
17.

Relationship between variant forms of estrogen receptor RNA and an apoptosis-related RNA, TRPM-2, with survival in patients with breast cancer.

Rennie PS, Mawji NR, Coldman AJ, Godolphin W, Jones EC, Vielkind JR, Bruchovsky N.

Cancer. 1993 Dec 15;72(12):3648-54.

18.

Tc1(Hin): a form of the transposable element Tc1 in Caenorhabditis elegans.

Rose AM, Harris LJ, Mawji NR, Morris WJ.

Can J Biochem Cell Biol. 1985 Jul;63(7):752-6.

PMID:
2994862

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