Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 281

1.

Tauroursodeoxycholic acid binds to the G-protein site on light activated rhodopsin.

Lobysheva E, Taylor CM, Marshall GR, Kisselev OG.

Exp Eye Res. 2018 Feb 16;170:51-57. doi: 10.1016/j.exer.2018.02.015. [Epub ahead of print]

2.

The testicular transcriptome associated with spermatogonia differentiation initiated by gonadotrophin stimulation in the juvenile rhesus monkey (Macaca mulatta).

Ramaswamy S, Walker WH, Aliberti P, Sethi R, Marshall GR, Smith A, Nourashrafeddin S, Belgorosky A, Chandran UR, Hedger MP, Plant TM.

Hum Reprod. 2017 Oct 1;32(10):2088-2100. doi: 10.1093/humrep/dex270.

PMID:
28938749
3.

Limiting Assumptions in the Design of Peptidomimetics.

Marshall GR, Ballante F.

Drug Dev Res. 2017 Sep;78(6):245-267. doi: 10.1002/ddr.21406. Epub 2017 Sep 6.

PMID:
28875546
4.

Combinations of isoform-targeted histone deacetylase inhibitors and bryostatin analogues display remarkable potency to activate latent HIV without global T-cell activation.

Albert BJ, Niu A, Ramani R, Marshall GR, Wender PA, Williams RM, Ratner L, Barnes AB, Kyei GB.

Sci Rep. 2017 Aug 7;7(1):7456. doi: 10.1038/s41598-017-07814-4.

5.

Structural insights of SmKDAC8 inhibitors: Targeting Schistosoma epigenetics through a combined structure-based 3D QSAR, in vitro and synthesis strategy.

Ballante F, Reddy DR, Zhou NJ, Marshall GR.

Bioorg Med Chem. 2017 Apr 1;25(7):2105-2132. doi: 10.1016/j.bmc.2017.02.020. Epub 2017 Feb 13.

PMID:
28259528
6.

Design and synthesis of benzodiazepine analogs as isoform-selective human lysine deacetylase inhibitors.

Reddy DR, Ballante F, Zhou NJ, Marshall GR.

Eur J Med Chem. 2017 Feb 15;127:531-553. doi: 10.1016/j.ejmech.2016.12.032. Epub 2016 Dec 18.

PMID:
28109947
7.

Esterase mutation is a mechanism of resistance to antimalarial compounds.

Istvan ES, Mallari JP, Corey VC, Dharia NV, Marshall GR, Winzeler EA, Goldberg DE.

Nat Commun. 2017 Jan 20;8:14240. doi: 10.1038/ncomms14240.

8.

Empathy and affect: what can empathied bodies do?

Marshall GR, Hooker C.

Med Humanit. 2016 Jun;42(2):128-34. doi: 10.1136/medhum-2015-010818. Epub 2016 Feb 8.

PMID:
26856355
9.

An Automated Strategy for Binding-Pose Selection and Docking Assessment in Structure-Based Drug Design.

Ballante F, Marshall GR.

J Chem Inf Model. 2016 Jan 25;56(1):54-72. doi: 10.1021/acs.jcim.5b00603. Epub 2016 Jan 6.

PMID:
26682916
10.

Design and Synthesis of Simplified Largazole Analogues as Isoform-Selective Human Lysine Deacetylase Inhibitors.

Reddy DN, Ballante F, Chuang T, Pirolli A, Marrocco B, Marshall GR.

J Med Chem. 2016 Feb 25;59(4):1613-33. doi: 10.1021/acs.jmedchem.5b01632. Epub 2016 Jan 7.

PMID:
26681404
11.

Targeting Lysine Deacetylases (KDACs) in Parasites.

Wang Q, Rosa BA, Nare B, Powell K, Valente S, Rotili D, Mai A, Marshall GR, Mitreva M.

PLoS Negl Trop Dis. 2015 Sep 24;9(9):e0004026. doi: 10.1371/journal.pntd.0004026. eCollection 2015.

12.

High-resolution crystal structures of protein helices reconciled with three-centered hydrogen bonds and multipole electrostatics.

Kuster DJ, Liu C, Fang Z, Ponder JW, Marshall GR.

PLoS One. 2015 Apr 20;10(4):e0123146. doi: 10.1371/journal.pone.0123146. eCollection 2015.

13.

Helix stability of oligoglycine, oligoalanine, and oligo-β-alanine dodecamers reflected by hydrogen-bond persistence.

Liu C, Ponder JW, Marshall GR.

Proteins. 2014 Nov;82(11):3043-61. doi: 10.1002/prot.24665. Epub 2014 Sep 20.

14.

Donor management parameters and organ yield: single center results.

Marshall GR, Mangus RS, Powelson JA, Fridell JA, Kubal CA, Tector AJ.

J Surg Res. 2014 Sep;191(1):208-13. doi: 10.1016/j.jss.2014.02.054. Epub 2014 Mar 3.

PMID:
24953985
15.

Fluorescence- and magnetic-activated cell sorting strategies to isolate and enrich human spermatogonial stem cells.

Valli H, Sukhwani M, Dovey SL, Peters KA, Donohue J, Castro CA, Chu T, Marshall GR, Orwig KE.

Fertil Steril. 2014 Aug;102(2):566-580.e7. doi: 10.1016/j.fertnstert.2014.04.036. Epub 2014 Jun 2.

16.

Spermatogonial SOHLH1 nucleocytoplasmic shuttling associates with initiation of spermatogenesis in the rhesus monkey (Macaca mulatta).

Ramaswamy S, Razack BS, Roslund RM, Suzuki H, Marshall GR, Rajkovic A, Plant TM.

Mol Hum Reprod. 2014 Apr;20(4):350-7. doi: 10.1093/molehr/gat093. Epub 2013 Dec 9.

17.

Mild to moderate pulmonary hypertension in liver transplantation.

Mangus RS, Kinsella SB, Marshall GR, Fridell JA, Wilkes KR, Tector AJ.

J Surg Res. 2013 Oct;184(2):1150-6. doi: 10.1016/j.jss.2013.04.040. Epub 2013 May 10.

PMID:
23870833
18.

Limiting assumptions in molecular modeling: electrostatics.

Marshall GR.

J Comput Aided Mol Des. 2013 Feb;27(2):107-14. doi: 10.1007/s10822-013-9634-x. Epub 2013 Jan 26.

19.

Molecular dynamics of β-hairpin models of epigenetic recognition motifs.

Zheng X, Wu C, Ponder JW, Marshall GR.

J Am Chem Soc. 2012 Sep 26;134(38):15970-8. Epub 2012 Sep 17.

20.

Comprehensive model of wild-type and mutant HIV-1 reverse transciptases.

Ballante F, Musmuca I, Marshall GR, Ragno R.

J Comput Aided Mol Des. 2012 Aug;26(8):907-19. doi: 10.1007/s10822-012-9586-6. Epub 2012 Jul 26.

PMID:
22833004
21.

Histone deacetylase inhibitors: structure-based modeling and isoform-selectivity prediction.

Silvestri L, Ballante F, Mai A, Marshall GR, Ragno R.

J Chem Inf Model. 2012 Aug 27;52(8):2215-35. doi: 10.1021/ci300160y. Epub 2012 Jul 19.

PMID:
22762501
22.

Inhibition of bacterial virulence: drug-like molecules targeting the Salmonella enterica PhoP response regulator.

Tang YT, Gao R, Havranek JJ, Groisman EA, Stock AM, Marshall GR.

Chem Biol Drug Des. 2012 Jun;79(6):1007-17. doi: 10.1111/j.1747-0285.2012.01362.x. Epub 2012 Mar 21.

23.

Sertoli cell differentiation in rhesus monkey (Macaca mulatta) is an early event in puberty and precedes attainment of the adult complement of undifferentiated spermatogonia.

Simorangkir DR, Ramaswamy S, Marshall GR, Roslund R, Plant TM.

Reproduction. 2012 Apr;143(4):513-22. doi: 10.1530/REP-11-0411. Epub 2012 Jan 9.

24.

Limiting assumptions in structure-based design: binding entropy.

Marshall GR.

J Comput Aided Mol Des. 2012 Jan;26(1):3-8. doi: 10.1007/s10822-011-9494-1. Epub 2012 Jan 3. Review.

25.

Difference between restoring and predicting 3D structures of the loops in G-protein-coupled receptors by molecular modeling.

Nikiforovich GV, Taylor CM, Marshall GR, Baranski TJ.

Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):E341; author reply E342. doi: 10.1073/pnas.1107702108. Epub 2011 Jul 1. No abstract available.

26.

Drug-like leads for steric discrimination between substrate and inhibitors of human acetylcholinesterase.

Wildman SA, Zheng X, Sept D, Auletta JT, Rosenberry TL, Marshall GR.

Chem Biol Drug Des. 2011 Oct;78(4):495-504. doi: 10.1111/j.1747-0285.2011.01157.x. Epub 2011 Aug 22.

27.

Virtual screening for lead discovery.

Tang YT, Marshall GR.

Methods Mol Biol. 2011;716:1-22. doi: 10.1007/978-1-61779-012-6_1.

PMID:
21318897
28.

Simplified modeling approach suggests structural mechanisms for constitutive activation of the C5a receptor.

Nikiforovich GV, Marshall GR, Baranski TJ.

Proteins. 2011 Mar;79(3):787-802. doi: 10.1002/prot.22918. Epub 2010 Nov 30.

29.

PHOENIX: a scoring function for affinity prediction derived using high-resolution crystal structures and calorimetry measurements.

Tang YT, Marshall GR.

J Chem Inf Model. 2011 Feb 28;51(2):214-28. doi: 10.1021/ci100257s. Epub 2011 Jan 7.

30.

SKATE: a docking program that decouples systematic sampling from scoring.

Feng JA, Marshall GR.

J Comput Chem. 2010 Nov 15;31(14):2540-54. doi: 10.1002/jcc.21545.

PMID:
20740553
31.

Electron paramagnetic resonance studies of functionally active, nitroxide spin-labeled peptide analogues of the C-terminus of a G-protein alpha subunit.

Van Eps N, Anderson LL, Kisselev OG, Baranski TJ, Hubbell WL, Marshall GR.

Biochemistry. 2010 Aug 17;49(32):6877-86. doi: 10.1021/bi100846c.

32.

Using ligand-based virtual screening to allosterically stabilize the activated state of a GPCR.

Taylor CM, Rockweiler NB, Liu C, Rikimaru L, Tunemalm AK, Kisselev OG, Marshall GR.

Chem Biol Drug Des. 2010 Mar;75(3):325-32. doi: 10.1111/j.1747-0285.2009.00944.x. Epub 2010 Jan 19.

33.

Synthesis of the phenylpyridal scaffold as a helical peptide mimetic.

Bourne GT, Kuster DJ, Marshall GR.

Chemistry. 2010 Jul 26;16(28):8439-45. doi: 10.1002/chem.201000315.

34.

Targeting the dimerization of epidermal growth factor receptors with small-molecule inhibitors.

Yang RY, Yang KS, Pike LJ, Marshall GR.

Chem Biol Drug Des. 2010 Jul;76(1):1-9. doi: 10.1111/j.1747-0285.2010.00986.x. Epub 2010 May 4.

35.

A second look at mini-protein stability: analysis of FSD-1 using circular dichroism, differential scanning calorimetry, and simulations.

Feng JA, Kao J, Marshall GR.

Biophys J. 2009 Nov 18;97(10):2803-10. doi: 10.1016/j.bpj.2009.08.046.

36.

Modeling the possible conformations of the extracellular loops in G-protein-coupled receptors.

Nikiforovich GV, Taylor CM, Marshall GR, Baranski TJ.

Proteins. 2010 Feb 1;78(2):271-85. doi: 10.1002/prot.22537.

37.

Chemogenomics with protein secondary-structure mimetics.

Marshall GR, Kuster DJ, Che Y.

Methods Mol Biol. 2009;575:123-58. doi: 10.1007/978-1-60761-274-2_5. Review.

PMID:
19727613
38.

A crowdsourcing evaluation of the NIH chemical probes.

Oprea TI, Bologa CG, Boyer S, Curpan RF, Glen RC, Hopkins AL, Lipinski CA, Marshall GR, Martin YC, Ostopovici-Halip L, Rishton G, Ursu O, Vaz RJ, Waller C, Waldmann H, Sklar LA.

Nat Chem Biol. 2009 Jul;5(7):441-7. doi: 10.1038/nchembio0709-441. Erratum in: Nat Chem Biol. 2009 Aug;5(8):600.

39.

Estrogen promotes germ cell and seminiferous tubule development in the baboon fetal testis.

Albrecht ED, Lane MV, Marshall GR, Merchenthaler I, Simorangkir DR, Pohl CR, Plant TM, Pepe GJ.

Biol Reprod. 2009 Aug;81(2):406-14. doi: 10.1095/biolreprod.108.073494. Epub 2009 Apr 29.

40.

A re-examination of proliferation and differentiation of type A spermatogonia in the adult rhesus monkey (Macaca mulatta).

Simorangkir DR, Marshall GR, Plant TM.

Hum Reprod. 2009 Jul;24(7):1596-604. doi: 10.1093/humrep/dep051. Epub 2009 Mar 12.

41.

A selective monotropic elevation of FSH, but not that of LH, amplifies the proliferation and differentiation of spermatogonia in the adult rhesus monkey (Macaca mulatta).

Simorangkir DR, Ramaswamy S, Marshall GR, Pohl CR, Plant TM.

Hum Reprod. 2009 Jul;24(7):1584-95. doi: 10.1093/humrep/dep052. Epub 2009 Mar 11.

42.

A virtual library of constrained cyclic tetrapeptides that mimics all four side-chain orientations for over half the reverse turns in the protein data bank.

Arbor S, Marshall GR.

J Comput Aided Mol Des. 2009 Feb;23(2):87-95. doi: 10.1007/s10822-008-9241-4. Epub 2008 Sep 17.

PMID:
18797997
43.

Modulating G-protein coupled receptor/G-protein signal transduction by small molecules suggested by virtual screening.

Taylor CM, Barda Y, Kisselev OG, Marshall GR.

J Med Chem. 2008 Sep 11;51(17):5297-303. doi: 10.1021/jm800326q. Epub 2008 Aug 16.

44.

Modeling molecular mechanisms of binding of the anaphylatoxin C5a to the C5a receptor.

Nikiforovich GV, Marshall GR, Baranski TJ.

Biochemistry. 2008 Mar 11;47(10):3117-30. doi: 10.1021/bi702321a. Epub 2008 Feb 15.

PMID:
18275159
45.

The biology and future prospects of antivirulence therapies.

Cegelski L, Marshall GR, Eldridge GR, Hultgren SJ.

Nat Rev Microbiol. 2008 Jan;6(1):17-27. Review. Erratum in: Nat Rev Microbiol. 2009 Nov;7(11):836.

46.

Privileged scaffolds targeting reverse-turn and helix recognition.

Che Y, Marshall GR.

Expert Opin Ther Targets. 2008 Jan;12(1):101-14. Review.

PMID:
18076374
47.

The early years--across the bench from Bruce (1963-1966).

Marshall GR.

Biopolymers. 2008;90(3):190-9.

PMID:
17941005
48.
49.
50.

Design, synthesis, and metal binding of novel Pseudo- oligopeptides containing two phosphinic acid groups.

Ye Y, Liu M, Kao JL, Marshall GR.

Biopolymers. 2008 Jan;89(1):72-85.

PMID:
17910046

Supplemental Content

Loading ...
Support Center