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Items: 1 to 50 of 191

1.

Linear array of multi-substrate tracts for simultaneous assessment of cell adhesion, migration, and differentiation.

Moreno-Rodriguez RA, Krug EL, Reyes L, Markwald RR.

Biotechniques. 2017 Dec 1;63(6):267-274. doi: 10.2144/000114619.

2.

Transforming growth factor β1 (TGFβ1) regulates CD44V6 expression and activity through extracellular signal-regulated kinase (ERK)-induced EGR1 in pulmonary fibrogenic fibroblasts.

Ghatak S, Markwald RR, Hascall VC, Dowling W, Lottes RG, Baatz JE, Beeson G, Beeson CC, Perrella MA, Thannickal VJ, Misra S.

J Biol Chem. 2017 Jun 23;292(25):10465-10489. doi: 10.1074/jbc.M116.752451. Epub 2017 Apr 7.

PMID:
28389562
3.

Transforming growth factor β1 (TGFβ1)-induced CD44V6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis.

Ghatak S, Hascall VC, Markwald RR, Feghali-Bostwick C, Artlett CM, Gooz M, Bogatkevich GS, Atanelishvili I, Silver RM, Wood J, Thannickal VJ, Misra S.

J Biol Chem. 2017 Jun 23;292(25):10490-10519. doi: 10.1074/jbc.M116.752469. Epub 2017 Apr 7.

PMID:
28389561
4.

MVP-Associated Filamin A Mutations Affect FlnA-PTPN12 (PTP-PEST) Interactions.

Duval D, Labbé P, Bureau L, Le Tourneau T, Norris RA, Markwald RR, Levine R, Schott JJ, Mérot J.

J Cardiovasc Dev Dis. 2015 Sep 8;2(3):233-247.

5.

Morning Circadian Misalignment during Short Sleep Duration Impacts Insulin Sensitivity.

Eckel RH, Depner CM, Perreault L, Markwald RR, Smith MR, McHill AW, Higgins J, Melanson EL, Wright KP Jr.

Curr Biol. 2015 Nov 16;25(22):3004-10. doi: 10.1016/j.cub.2015.10.011. Epub 2015 Nov 5.

6.

Mitral valve disease--morphology and mechanisms.

Levine RA, Hagége AA, Judge DP, Padala M, Dal-Bianco JP, Aikawa E, Beaudoin J, Bischoff J, Bouatia-Naji N, Bruneval P, Butcher JT, Carpentier A, Chaput M, Chester AH, Clusel C, Delling FN, Dietz HC, Dina C, Durst R, Fernandez-Friera L, Handschumacher MD, Jensen MO, Jeunemaitre XP, Le Marec H, Le Tourneau T, Markwald RR, Mérot J, Messas E, Milan DP, Neri T, Norris RA, Peal D, Perrocheau M, Probst V, Pucéat M, Rosenthal N, Solis J, Schott JJ, Schwammenthal E, Slaugenhaupt SA, Song JK, Yacoub MH; Leducq Mitral Transatlantic Network.

Nat Rev Cardiol. 2015 Dec;12(12):689-710. doi: 10.1038/nrcardio.2015.161. Epub 2015 Oct 20. Review.

7.

Increased Infiltration of Extra-Cardiac Cells in Myxomatous Valve Disease.

Sauls K, Toomer K, Williams K, Johnson AJ, Markwald RR, Hajdu Z, Norris RA.

J Cardiovasc Dev Dis. 2015 Sep;2(3):200-213. Epub 2015 Jul 24.

8.

Roles of Proteoglycans and Glycosaminoglycans in Wound Healing and Fibrosis.

Ghatak S, Maytin EV, Mack JA, Hascall VC, Atanelishvili I, Moreno Rodriguez R, Markwald RR, Misra S.

Int J Cell Biol. 2015;2015:834893. doi: 10.1155/2015/834893. Epub 2015 Sep 10. Review.

9.

Utilization of Glycosaminoglycans/Proteoglycans as Carriers for Targeted Therapy Delivery.

Misra S, Hascall VC, Atanelishvili I, Moreno Rodriguez R, Markwald RR, Ghatak S.

Int J Cell Biol. 2015;2015:537560. doi: 10.1155/2015/537560. Epub 2015 Sep 10. Review.

10.

Effects of caffeine on the human circadian clock in vivo and in vitro.

Burke TM, Markwald RR, McHill AW, Chinoy ED, Snider JA, Bessman SC, Jung CM, O'Neill JS, Wright KP Jr.

Sci Transl Med. 2015 Sep 16;7(305):305ra146. doi: 10.1126/scitranslmed.aac5125.

11.

Genetic association analyses highlight biological pathways underlying mitral valve prolapse.

Dina C, Bouatia-Naji N, Tucker N, Delling FN, Toomer K, Durst R, Perrocheau M, Fernandez-Friera L, Solis J; PROMESA investigators, Le Tourneau T, Chen MH, Probst V, Bosse Y, Pibarot P, Zelenika D, Lathrop M, Hercberg S, Roussel R, Benjamin EJ, Bonnet F, Lo SH, Dolmatova E, Simonet F, Lecointe S, Kyndt F, Redon R, Le Marec H, Froguel P, Ellinor PT, Vasan RS, Bruneval P, Markwald RR, Norris RA, Milan DJ, Slaugenhaupt SA, Levine RA, Schott JJ, Hagege AA; MVP-France, Jeunemaitre X; Leducq Transatlantic MITRAL Network.

Nat Genet. 2015 Oct;47(10):1206-11. doi: 10.1038/ng.3383. Epub 2015 Aug 24.

12.

Performance of a Portable Sleep Monitoring Device in Individuals with High Versus Low Sleep Efficiency.

Markwald RR, Bessman SC, Reini SA, Drummond SP.

J Clin Sleep Med. 2016 Jan;12(1):95-103. doi: 10.5664/jcsm.5404.

13.

Mutations in DCHS1 cause mitral valve prolapse.

Durst R, Sauls K, Peal DS, deVlaming A, Toomer K, Leyne M, Salani M, Talkowski ME, Brand H, Perrocheau M, Simpson C, Jett C, Stone MR, Charles F, Chiang C, Lynch SN, Bouatia-Naji N, Delling FN, Freed LA, Tribouilloy C, Le Tourneau T, LeMarec H, Fernandez-Friera L, Solis J, Trujillano D, Ossowski S, Estivill X, Dina C, Bruneval P, Chester A, Schott JJ, Irvine KD, Mao Y, Wessels A, Motiwala T, Puceat M, Tsukasaki Y, Menick DR, Kasiganesan H, Nie X, Broome AM, Williams K, Johnson A, Markwald RR, Jeunemaitre X, Hagege A, Levine RA, Milan DJ, Norris RA, Slaugenhaupt SA.

Nature. 2015 Sep 3;525(7567):109-13. doi: 10.1038/nature14670. Epub 2015 Aug 10.

14.

Interactions between Hyaluronan and Its Receptors (CD44, RHAMM) Regulate the Activities of Inflammation and Cancer.

Misra S, Hascall VC, Markwald RR, Ghatak S.

Front Immunol. 2015 May 6;6:201. doi: 10.3389/fimmu.2015.00201. eCollection 2015. Review.

15.

Isothiocyanate analogs targeting CD44 receptor as an effective strategy against colon cancer.

Misra S, Ghatak S, Vyas A, O'Brien P, Markwald RR, Khetmalas M, Hascall VC, McCarthy JB, Karamanos NK, Tammi MI, Tammi RH, Prestwitch GD, Padhye S.

Med Chem Res. 2014 Aug 1;23(8):3836-3851.

16.

Study of droplet formation process during drop-on-demand inkjetting of living cell-laden bioink.

Xu C, Zhang M, Huang Y, Ogale A, Fu J, Markwald RR.

Langmuir. 2014 Aug 5;30(30):9130-8. doi: 10.1021/la501430x. Epub 2014 Jul 21.

PMID:
25005170
17.

Engineering alginate as bioink for bioprinting.

Jia J, Richards DJ, Pollard S, Tan Y, Rodriguez J, Visconti RP, Trusk TC, Yost MJ, Yao H, Markwald RR, Mei Y.

Acta Biomater. 2014 Oct;10(10):4323-31. doi: 10.1016/j.actbio.2014.06.034. Epub 2014 Jul 1.

18.

3D printing facilitated scaffold-free tissue unit fabrication.

Tan Y, Richards DJ, Trusk TC, Visconti RP, Yost MJ, Kindy MS, Drake CJ, Argraves WS, Markwald RR, Mei Y.

Biofabrication. 2014 Jun;6(2):024111. doi: 10.1088/1758-5082/6/2/024111. Epub 2014 Apr 10.

19.

Periostin induces intracellular cross-talk between kinases and hyaluronan in atrioventricular valvulogenesis.

Ghatak S, Misra S, Norris RA, Moreno-Rodriguez RA, Hoffman S, Levine RA, Hascall VC, Markwald RR.

J Biol Chem. 2014 Mar 21;289(12):8545-61. doi: 10.1074/jbc.M113.539882. Epub 2014 Jan 27.

20.

Overexpression of c-Met and CD44v6 receptors contributes to autocrine TGF-β1 signaling in interstitial lung disease.

Ghatak S, Bogatkevich GS, Atnelishvili I, Akter T, Feghali-Bostwick C, Hoffman S, Fresco VM, Fuchs JC, Visconti RP, Markwald RR, Padhye SB, Silver RM, Hascall VC, Misra S.

J Biol Chem. 2014 Mar 14;289(11):7856-72. doi: 10.1074/jbc.M113.505065. Epub 2013 Dec 9.

21.

Novel di-tertiary-butyl phenylhydrazones as dual cyclooxygenase-2/5-lipoxygenase inhibitors: synthesis, COX/LOX inhibition, molecular modeling, and insights into their cytotoxicities.

Ghatak S, Vyas A, Misra S, O'Brien P, Zambre A, Fresco VM, Markwald RR, Swamy KV, Afrasiabi Z, Choudhury A, Khetmalas M, Padhye S.

Bioorg Med Chem Lett. 2014 Jan 1;24(1):317-24. doi: 10.1016/j.bmcl.2013.11.015. Epub 2013 Nov 17.

PMID:
24295787
22.

Valvular dystrophy associated filamin A mutations reveal a new role of its first repeats in small-GTPase regulation.

Duval D, Lardeux A, Le Tourneau T, Norris RA, Markwald RR, Sauzeau V, Probst V, Le Marec H, Levine R, Schott JJ, Merot J.

Biochim Biophys Acta. 2014 Feb;1843(2):234-44. doi: 10.1016/j.bbamcr.2013.10.022. Epub 2013 Nov 4.

23.

Combination of light and melatonin time cues for phase advancing the human circadian clock.

Burke TM, Markwald RR, Chinoy ED, Snider JA, Bessman SC, Jung CM, Wright KP Jr.

Sleep. 2013 Nov 1;36(11):1617-24. doi: 10.5665/sleep.3110.

24.

Cellularized microcarriers as adhesive building blocks for fabrication of tubular tissue constructs.

Twal WO, Klatt SC, Harikrishnan K, Gerges E, Cooley MA, Trusk TC, Zhou B, Gabr MG, Shazly T, Lessner SM, Markwald RR, Argraves WS.

Ann Biomed Eng. 2014 Jul;42(7):1470-81. doi: 10.1007/s10439-013-0883-6. Epub 2013 Aug 14.

25.

miR-21 represses Pdcd4 during cardiac valvulogenesis.

Kolpa HJ, Peal DS, Lynch SN, Giokas AC, Ghatak S, Misra S, Norris RA, Macrae CA, Markwald RR, Ellinor P, Bischoff J, Milan DJ.

Development. 2013 May;140(10):2172-80. doi: 10.1242/dev.084475. Epub 2013 Apr 11.

26.

Impact of insufficient sleep on total daily energy expenditure, food intake, and weight gain.

Markwald RR, Melanson EL, Smith MR, Higgins J, Perreault L, Eckel RH, Wright KP Jr.

Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5695-700. doi: 10.1073/pnas.1216951110. Epub 2013 Mar 11.

27.

Mesenchymal stem cell-cardiomyocyte interactions under defined contact modes on laser-patterned biochips.

Ma Z, Yang H, Liu H, Xu M, Runyan RB, Eisenberg CA, Markwald RR, Borg TK, Gao BZ.

PLoS One. 2013;8(2):e56554. doi: 10.1371/journal.pone.0056554. Epub 2013 Feb 13.

28.

Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signaling.

Wu B, Zhang Z, Lui W, Chen X, Wang Y, Chamberlain AA, Moreno-Rodriguez RA, Markwald RR, O'Rourke BP, Sharp DJ, Zheng D, Lenz J, Baldwin HS, Chang CP, Zhou B.

Cell. 2012 Nov 21;151(5):1083-96. doi: 10.1016/j.cell.2012.10.023.

29.

Developmental basis for filamin-A-associated myxomatous mitral valve disease.

Sauls K, de Vlaming A, Harris BS, Williams K, Wessels A, Levine RA, Slaugenhaupt SA, Goodwin RL, Pavone LM, Merot J, Schott JJ, Le Tourneau T, Dix T, Jesinkey S, Feng Y, Walsh C, Zhou B, Baldwin S, Markwald RR, Norris RA.

Cardiovasc Res. 2012 Oct 1;96(1):109-19. doi: 10.1093/cvr/cvs238. Epub 2012 Jul 25.

30.

Scaffold-free inkjet printing of three-dimensional zigzag cellular tubes.

Xu C, Chai W, Huang Y, Markwald RR.

Biotechnol Bioeng. 2012 Dec;109(12):3152-60. doi: 10.1002/bit.24591. Epub 2012 Jul 19.

PMID:
22767299
31.

Atrioventricular valve development: new perspectives on an old theme.

de Vlaming A, Sauls K, Hajdu Z, Visconti RP, Mehesz AN, Levine RA, Slaugenhaupt SA, Hagège A, Chester AH, Markwald RR, Norris RA.

Differentiation. 2012 Jul;84(1):103-16. doi: 10.1016/j.diff.2012.04.001. Epub 2012 May 11. Review.

32.

Periostin Expression is Altered in Aortic Valves in Smad6 Mutant Mice.

Sugi Y, Kern MJ, Markwald RR, Burnside JL.

J Neonatal Biol. 2012 Jan 21;1. pii: 4692.

33.

Translational research on the mitral valve: from developmental mechanisms to new therapies.

Judge DP, Markwald RR, Hagège AA, Levine RA.

J Cardiovasc Transl Res. 2011 Dec;4(6):699-701. doi: 10.1007/s12265-011-9320-0. Epub 2011 Sep 7. No abstract available.

34.

Recruitment of bone marrow-derived valve interstitial cells is a normal homeostatic process.

Hajdu Z, Romeo SJ, Fleming PA, Markwald RR, Visconti RP, Drake CJ.

J Mol Cell Cardiol. 2011 Dec;51(6):955-65. doi: 10.1016/j.yjmcc.2011.08.006. Epub 2011 Aug 16.

35.

Megahertz streak-mode Fourier domain optical coherence tomography.

Wang R, Yun JX, Yuan X, Goodwin R, Markwald RR, Gao BZ.

J Biomed Opt. 2011 Jun;16(6):066016. doi: 10.1117/1.3593149.

36.

Scalable robotic biofabrication of tissue spheroids.

Mehesz AN, Brown J, Hajdu Z, Beaver W, da Silva JV, Visconti RP, Markwald RR, Mironov V.

Biofabrication. 2011 Jun;3(2):025002. doi: 10.1088/1758-5082/3/2/025002. Epub 2011 May 12.

37.

Combined inhibition of nitric oxide and vasodilating prostaglandins abolishes forearm vasodilatation to systemic hypoxia in healthy humans.

Markwald RR, Kirby BS, Crecelius AR, Carlson RE, Voyles WF, Dinenno FA.

J Physiol. 2011 Apr 15;589(Pt 8):1979-90. doi: 10.1113/jphysiol.2011.205013. Epub 2011 Feb 21.

38.

Organ printing: from bioprinter to organ biofabrication line.

Mironov V, Kasyanov V, Markwald RR.

Curr Opin Biotechnol. 2011 Oct;22(5):667-73. doi: 10.1016/j.copbio.2011.02.006. Epub 2011 Mar 16. Review.

PMID:
21419621
39.

Accessory atrioventricular myocardial pathways in mouse heart development: substrate for supraventricular tachycardias.

Hahurij ND, Kolditz DP, Bökenkamp R, Markwald RR, Schalij MJ, Poelmann RE, Gittenberger-De Groot AC, Blom NA.

Pediatr Res. 2011 Jul;70(1):37-43. doi: 10.1203/PDR.0b013e3182192bfa.

PMID:
21399557
40.

Hyaluronan-CD44 interactions as potential targets for cancer therapy.

Misra S, Heldin P, Hascall VC, Karamanos NK, Skandalis SS, Markwald RR, Ghatak S.

FEBS J. 2011 May;278(9):1429-43. doi: 10.1111/j.1742-4658.2011.08071.x. Epub 2011 Mar 25. Review.

41.

Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β.

Teekakirikul P, Eminaga S, Toka O, Alcalai R, Wang L, Wakimoto H, Nayor M, Konno T, Gorham JM, Wolf CM, Kim JB, Schmitt JP, Molkentin JD, Norris RA, Tager AM, Hoffman SR, Markwald RR, Seidman CE, Seidman JG.

J Clin Invest. 2010 Oct;120(10):3520-9. doi: 10.1172/JCI42028. Epub 2010 Sep 1.

42.

Tissue spheroid fusion-based in vitro screening assays for analysis of tissue maturation.

Hajdu Z, Mironov V, Mehesz AN, Norris RA, Markwald RR, Visconti RP.

J Tissue Eng Regen Med. 2010 Dec;4(8):659-64. doi: 10.1002/term.291.

43.

Effects of the melatonin MT-1/MT-2 agonist ramelteon on daytime body temperature and sleep.

Markwald RR, Lee-Chiong TL, Burke TM, Snider JA, Wright KP Jr.

Sleep. 2010 Jun;33(6):825-31.

44.

Expression of the familial cardiac valvular dystrophy gene, filamin-A, during heart morphogenesis.

Norris RA, Moreno-Rodriguez R, Wessels A, Merot J, Bruneval P, Chester AH, Yacoub MH, Hagège A, Slaugenhaupt SA, Aikawa E, Schott JJ, Lardeux A, Harris BS, Williams LK, Richards A, Levine RA, Markwald RR.

Dev Dyn. 2010 Jul;239(7):2118-27. doi: 10.1002/dvdy.22346.

45.

Developmental basis of adult cardiovascular diseases: valvular heart diseases.

Markwald RR, Norris RA, Moreno-Rodriguez R, Levine RA.

Ann N Y Acad Sci. 2010 Feb;1188:177-83. doi: 10.1111/j.1749-6632.2009.05098.x. Review.

46.

Stromal hyaluronan interaction with epithelial CD44 variants promotes prostate cancer invasiveness by augmenting expression and function of hepatocyte growth factor and androgen receptor.

Ghatak S, Hascall VC, Markwald RR, Misra S.

J Biol Chem. 2010 Jun 25;285(26):19821-32. doi: 10.1074/jbc.M110.104273. Epub 2010 Mar 3.

47.

Towards organ printing: engineering an intra-organ branched vascular tree.

Visconti RP, Kasyanov V, Gentile C, Zhang J, Markwald RR, Mironov V.

Expert Opin Biol Ther. 2010 Mar;10(3):409-20. doi: 10.1517/14712590903563352. Review.

48.

Computational modeling of epithelial-mesenchymal transformations.

Neagu A, Mironov V, Kosztin I, Barz B, Neagu M, Moreno-Rodriguez RA, Markwald RR, Forgacs G.

Biosystems. 2010 Apr;100(1):23-30. doi: 10.1016/j.biosystems.2009.12.004. Epub 2009 Dec 31.

49.

The many facets of the matricelluar protein periostin during cardiac development, remodeling, and pathophysiology.

Norris RA, Moreno-Rodriguez R, Hoffman S, Markwald RR.

J Cell Commun Signal. 2009 Dec;3(3-4):275-86. doi: 10.1007/s12079-009-0063-5. Epub 2009 Oct 2.

50.

Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease.

Tkatchenko TV, Moreno-Rodriguez RA, Conway SJ, Molkentin JD, Markwald RR, Tkatchenko AV.

Physiol Genomics. 2009 Nov 6;39(3):160-8. doi: 10.1152/physiolgenomics.00078.2009. Epub 2009 Sep 1.

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