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Items: 13


Cleavage activates dispatched for Sonic Hedgehog ligand release.

Stewart DP, Marada S, Bodeen WJ, Truong A, Sakurada SM, Pandit T, Pruett-Miller SM, Ogden SK.

Elife. 2018 Jan 23;7. pii: e31678. doi: 10.7554/eLife.31678.


A fixation method to preserve cultured cell cytonemes facilitates mechanistic interrogation of morphogen transport.

Bodeen WJ, Marada S, Truong A, Ogden SK.

Development. 2017 Oct 1;144(19):3612-3624. doi: 10.1242/dev.152736. Epub 2017 Aug 21.


Higher-order oligomerization promotes localization of SPOP to liquid nuclear speckles.

Marzahn MR, Marada S, Lee J, Nourse A, Kenrick S, Zhao H, Ben-Nissan G, Kolaitis RM, Peters JL, Pounds S, Errington WJ, Privé GG, Taylor JP, Sharon M, Schuck P, Ogden SK, Mittag T.

EMBO J. 2016 Jun 15;35(12):1254-75. doi: 10.15252/embj.201593169. Epub 2016 May 23.


Dataset for phenotypic classification of genetic modifiers of smoothened and Hedgehog.

Marada S, Truong A, Ogden SK.

Data Brief. 2016 Mar 4;7:485-9. doi: 10.1016/j.dib.2016.02.076. eCollection 2016 Jun.


The small GTPase Rap1 is a modulator of Hedgehog signaling.

Marada S, Truong A, Ogden SK.

Dev Biol. 2016 Jan 1;409(1):84-94. doi: 10.1016/j.ydbio.2015.10.020. Epub 2015 Oct 19.


Smoothened Regulation: A Tale of Two Signals.

Arensdorf AM, Marada S, Ogden SK.

Trends Pharmacol Sci. 2016 Jan;37(1):62-72. doi: 10.1016/ Epub 2015 Sep 29. Review.


Functional Divergence in the Role of N-Linked Glycosylation in Smoothened Signaling.

Marada S, Navarro G, Truong A, Stewart DP, Arensdorf AM, Nachtergaele S, Angelats E, Opferman JT, Rohatgi R, McCormick PJ, Ogden SK.

PLoS Genet. 2015 Aug 20;11(8):e1005473. doi: 10.1371/journal.pgen.1005473. eCollection 2015 Aug.


Structural insights into the role of the Smoothened cysteine-rich domain in Hedgehog signalling.

Rana R, Carroll CE, Lee HJ, Bao J, Marada S, Grace CR, Guibao CD, Ogden SK, Zheng JJ.

Nat Commun. 2013;4:2965. doi: 10.1038/ncomms3965.


Inducible protein traps with dominant phenotypes for functional analysis of the Drosophila genome.

Singari S, Javeed N, Tardi NJ, Marada S, Carlson JC, Kirk S, Thorn JM, Edwards KA.

Genetics. 2014 Jan;196(1):91-105. doi: 10.1534/genetics.113.157529. Epub 2013 Oct 30.


The unfolded protein response selectively targets active smoothened mutants.

Marada S, Stewart DP, Bodeen WJ, Han YG, Ogden SK.

Mol Cell Biol. 2013 Jun;33(12):2375-87. doi: 10.1128/MCB.01445-12. Epub 2013 Apr 9.


An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia.

Gruber TA, Larson Gedman A, Zhang J, Koss CS, Marada S, Ta HQ, Chen SC, Su X, Ogden SK, Dang J, Wu G, Gupta V, Andersson AK, Pounds S, Shi L, Easton J, Barbato MI, Mulder HL, Manne J, Wang J, Rusch M, Ranade S, Ganti R, Parker M, Ma J, Radtke I, Ding L, Cazzaniga G, Biondi A, Kornblau SM, Ravandi F, Kantarjian H, Nimer SD, Döhner K, Döhner H, Ley TJ, Ballerini P, Shurtleff S, Tomizawa D, Adachi S, Hayashi Y, Tawa A, Shih LY, Liang DC, Rubnitz JE, Pui CH, Mardis ER, Wilson RK, Downing JR.

Cancer Cell. 2012 Nov 13;22(5):683-97. doi: 10.1016/j.ccr.2012.10.007.


Drosophila Pez acts in Hippo signaling to restrict intestinal stem cell proliferation.

Poernbacher I, Baumgartner R, Marada SK, Edwards K, Stocker H.

Curr Biol. 2012 Mar 6;22(5):389-96. doi: 10.1016/j.cub.2012.01.019. Epub 2012 Feb 2.


The extracellular loops of Smoothened play a regulatory role in control of Hedgehog pathway activation.

Carroll CE, Marada S, Stewart DP, Ouyang JX, Ogden SK.

Development. 2012 Feb;139(3):612-21. doi: 10.1242/dev.075614. Erratum in: Development. 2012 Feb;139(4):827.

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