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An OX40/OX40L interaction directs successful immunity to hepatitis B virus.

Publicover J, Gaggar A, Jespersen JM, Halac U, Johnson AJ, Goodsell A, Avanesyan L, Nishimura SL, Holdorf M, Mansfield KG, Judge JB, Koshti A, Croft M, Wakil AE, Rosenthal P, Pai E, Cooper S, Baron JL.

Sci Transl Med. 2018 Mar 21;10(433). pii: eaah5766. doi: 10.1126/scitranslmed.aah5766.


Dermaseptins as potential antirabies compounds.

Mechlia MB, Belaid A, Castel G, Jallet C, Mansfield KL, Fooks AR, Hani K, Tordo N.

Vaccine. 2018 Feb 10. pii: S0264-410X(18)30127-0. doi: 10.1016/j.vaccine.2018.01.066. [Epub ahead of print]


Trimethoprim use for urinary tract infection and risk of adverse outcomes in older patients: cohort study.

Crellin E, Mansfield KE, Leyrat C, Nitsch D, Douglas IJ, Root A, Williamson E, Smeeth L, Tomlinson LA.

BMJ. 2018 Feb 9;360:k341. doi: 10.1136/bmj.k341.


Acute kidney injury and infections in patients taking antihypertensive drugs: a self-controlled case series analysis.

Mansfield KE, Douglas IJ, Nitsch D, Thomas SL, Smeeth L, Tomlinson LA.

Clin Epidemiol. 2018 Jan 30;10:187-202. doi: 10.2147/CLEP.S146757. eCollection 2018.


'Involve Me and I Learn': Development of an Assessment Program for Research and Critical Analysis.

Mullan JR, Mansfield KJ, Weston KM, Rich W, Burns P, Brown C, McLennan PL.

J Med Educ Curric Dev. 2017 Feb 24;4:2382120517692539. doi: 10.1177/2382120517692539. eCollection 2017 Jan-Dec. Review.


Genomic Circuitry Underlying Immunological Response to Pediatric Acute Respiratory Infection.

Henrickson SE, Manne S, Dolfi DV, Mansfield KD, Parkhouse K, Mistry RD, Alpern ER, Hensley SE, Sullivan KE, Coffin SE, Wherry EJ.

Cell Rep. 2018 Jan 9;22(2):411-426. doi: 10.1016/j.celrep.2017.12.043.


Mannitol treatment is not effective in therapy of rabies virus infection in mice.

Dufkova L, Sirmarova J, Salat J, Honig V, Palus M, Ruzek D, Fooks AR, Mansfield KL, Tordo N, Jochmans D, Neyts J, Martina B, Koraka P, Osterhaus ADME; ASKLEPIOS consortium.

Vaccine. 2017 Dec 20. pii: S0264-410X(17)31781-4. doi: 10.1016/j.vaccine.2017.12.028. [Epub ahead of print]


First satellite tracks of South Atlantic sea turtle 'lost years': seasonal variation in trans-equatorial movement.

Mansfield KL, Mendilaharsu ML, Putman NF, Dei Marcovaldi MAG, Sacco AE, Lopez G, Pires T, Swimmer Y.

Proc Biol Sci. 2017 Dec 6;284(1868). pii: 20171730. doi: 10.1098/rspb.2017.1730.


Foraging and recruitment hotspot dynamics for the largest Atlantic loggerhead turtle rookery.

Ceriani SA, Weishampel JF, Ehrhart LM, Mansfield KL, Wunder MB.

Sci Rep. 2017 Dec 4;7(1):16894. doi: 10.1038/s41598-017-17206-3.


Transcription factor NF-κB is modulated by symbiotic status in a sea anemone model of cnidarian bleaching.

Mansfield KM, Carter NM, Nguyen L, Cleves PA, Alshanbayeva A, Williams LM, Crowder C, Penvose AR, Finnerty JR, Weis VM, Siggers TW, Gilmore TD.

Sci Rep. 2017 Nov 22;7(1):16025. doi: 10.1038/s41598-017-16168-w.


Biochemical monitoring after initiation of aldosterone antagonist therapy in users of renin-angiotensin system blockers: a UK primary care cohort study.

Sinnott SJ, Mansfield KE, Schmidt M, Bhaskaran K, Smeeth L, Nitsch D, Tomlinson LA.

BMJ Open. 2017 Nov 16;7(11):e018153. doi: 10.1136/bmjopen-2017-018153.


Re-evaluating the effect of Favipiravir treatment on rabies virus infection.

Banyard AC, Mansfield KL, Wu G, Selden D, Thorne L, Birch C, Koraka P, Osterhaus ADME, Fooks AR.

Vaccine. 2017 Nov 10. pii: S0264-410X(17)31541-4. doi: 10.1016/j.vaccine.2017.10.109. [Epub ahead of print]


A conserved Toll-like receptor-to-NF-κB signaling pathway in the endangered coral Orbicella faveolata.

Williams LM, Fuess LE, Brennan JJ, Mansfield KM, Salas-Rodriguez E, Welsh J, Awtry J, Banic S, Chacko C, Chezian A, Dowers D, Estrada F, Hsieh YH, Kang J, Li W, Malchiodi Z, Malinowski J, Matuszak S, McTigue T 4th, Mueller D, Nguyen B, Nguyen M, Nguyen P, Nguyen S, Njoku N, Patel K, Pellegrini W, Pliakas T, Qadir D, Ryan E, Schiffer A, Thiel A, Yunes SA, Spilios KE, Pinzón C JH, Mydlarz LD, Gilmore TD.

Dev Comp Immunol. 2018 Feb;79:128-136. doi: 10.1016/j.dci.2017.10.016. Epub 2017 Oct 26.


Cytokine release syndrome associated with chimeric-antigen receptor T-cell therapy: clinicopathological insights.

Obstfeld AE, Frey NV, Mansfield K, Lacey SF, June CH, Porter DL, Melenhorst JJ, Wasik MA.

Blood. 2017 Dec 7;130(23):2569-2572. doi: 10.1182/blood-2017-08-802413. Epub 2017 Oct 26. No abstract available.


An integrative review of the methodology and findings regarding dietary adherence in end stage kidney disease.

Lambert K, Mullan J, Mansfield K.

BMC Nephrol. 2017 Oct 23;18(1):318. doi: 10.1186/s12882-017-0734-z.


Should We Recommend Renal Diet-Related Apps to Our Patients? An Evaluation of the Quality and Health Literacy Demand of Renal Diet-Related Mobile Applications.

Lambert K, Mullan J, Mansfield K, Owen P.

J Ren Nutr. 2017 Nov;27(6):430-438. doi: 10.1053/j.jrn.2017.06.007.


Seventeen-Year Nationwide Trends in Antihypertensive Drug Use in Denmark.

Sundbøll J, Adelborg K, Mansfield KE, Tomlinson LA, Schmidt M.

Am J Cardiol. 2017 Dec 15;120(12):2193-2200. doi: 10.1016/j.amjcard.2017.08.042. Epub 2017 Sep 15.


Mood Disorders and Risk of Herpes Zoster in Two Population-Based Case-Control Studies in Denmark and the United Kingdom.

Schmidt SAJ, Langan SM, Pedersen HS, Schønheyder HC, Thomas SL, Smeeth L, Mansfield KE, Sørensen HT, Forbes HJ, Vestergaard M.

Am J Epidemiol. 2017 Oct 19. doi: 10.1093/aje/kwx338. [Epub ahead of print]


Modulating hemispheric lateralization by brain stimulation yields gain in mental and physical activity.

Zich C, Harty S, Kranczioch C, Mansfield KL, Sella F, Debener S, Cohen Kadosh R.

Sci Rep. 2017 Oct 18;7(1):13430. doi: 10.1038/s41598-017-13795-1.


The role of vaccination in risk mitigation and control of Newcastle disease in poultry.

Mayers J, Mansfield KL, Brown IH.

Vaccine. 2017 Oct 20;35(44):5974-5980. doi: 10.1016/j.vaccine.2017.09.008. Epub 2017 Sep 23. Review.


A natural ligand for the orphan receptor GPR15 modulates lymphocyte recruitment to epithelia.

Suply T, Hannedouche S, Carte N, Li J, Grosshans B, Schaefer M, Raad L, Beck V, Vidal S, Hiou-Feige A, Beluch N, Barbieri S, Wirsching J, Lageyre N, Hillger F, Debon C, Dawson J, Smith P, Lannoy V, Detheux M, Bitsch F, Falchetto R, Bouwmeester T, Porter J, Baumgarten B, Mansfield K, Carballido JM, Seuwen K, Bassilana F.

Sci Signal. 2017 Sep 12;10(496). pii: eaal0180. doi: 10.1126/scisignal.aal0180.


Emerging Tick-Borne Viruses in the Twenty-First Century.

Mansfield KL, Jizhou L, Phipps LP, Johnson N.

Front Cell Infect Microbiol. 2017 Jul 11;7:298. doi: 10.3389/fcimb.2017.00298. eCollection 2017. Review.


A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma.

O'Rourke DM, Nasrallah MP, Desai A, Melenhorst JJ, Mansfield K, Morrissette JJD, Martinez-Lage M, Brem S, Maloney E, Shen A, Isaacs R, Mohan S, Plesa G, Lacey SF, Navenot JM, Zheng Z, Levine BL, Okada H, June CH, Brogdon JL, Maus MV.

Sci Transl Med. 2017 Jul 19;9(399). pii: eaaa0984. doi: 10.1126/scitranslmed.aaa0984.


N6-methyladenosine is required for the hypoxic stabilization of specific mRNAs.

Fry NJ, Law BA, Ilkayeva OR, Holley CL, Mansfield KD.

RNA. 2017 Sep;23(9):1444-1455. doi: 10.1261/rna.061044.117. Epub 2017 Jun 13.


The P2X7 receptor is not essential for development of imiquimod-induced psoriasis-like inflammation in mice.

Geraghty NJ, Mansfield KJ, Fuller SJ, Watson D, Sluyter R.

Purinergic Signal. 2017 Dec;13(4):405-415. doi: 10.1007/s11302-017-9569-0. Epub 2017 Jun 8.


Discovery and Optimization of HKT288, a Cadherin-6-Targeting ADC for the Treatment of Ovarian and Renal Cancers.

Bialucha CU, Collins SD, Li X, Saxena P, Zhang X, Dürr C, Lafont B, Prieur P, Shim Y, Mosher R, Lee D, Ostrom L, Hu T, Bilic S, Rajlic IL, Capka V, Jiang W, Wagner JP, Elliott G, Veloso A, Piel JC, Flaherty MM, Mansfield KG, Meseck EK, Rubic-Schneider T, London AS, Tschantz WR, Kurz M, Nguyen D, Bourret A, Meyer MJ, Faris JE, Janatpour MJ, Chan VW, Yoder NC, Catcott KC, McShea MA, Sun X, Gao H, Williams J, Hofmann F, Engelman JA, Ettenberg SA, Sellers WR, Lees E.

Cancer Discov. 2017 Sep;7(9):1030-1045. doi: 10.1158/2159-8290.CD-16-1414. Epub 2017 May 19.


Tick-Pathogen Interactions and Vector Competence: Identification of Molecular Drivers for Tick-Borne Diseases.

de la Fuente J, Antunes S, Bonnet S, Cabezas-Cruz A, Domingos AG, Estrada-Peña A, Johnson N, Kocan KM, Mansfield KL, Nijhof AM, Papa A, Rudenko N, Villar M, Alberdi P, Torina A, Ayllón N, Vancova M, Golovchenko M, Grubhoffer L, Caracappa S, Fooks AR, Gortazar C, Rego ROM.

Front Cell Infect Microbiol. 2017 Apr 7;7:114. doi: 10.3389/fcimb.2017.00114. eCollection 2017. Review.


Prevalence, incidence, indication, and choice of antidepressants in patients with and without chronic kidney disease: a matched cohort study in UK Clinical Practice Research Datalink.

Iwagami M, Tomlinson LA, Mansfield KE, McDonald HI, Smeeth L, Nitsch D.

Pharmacoepidemiol Drug Saf. 2017 Jul;26(7):792-801. doi: 10.1002/pds.4212. Epub 2017 Apr 11.


Hypoxia and Hypoglycemia synergistically regulate mRNA stability.

Carraway KR, Johnson EM, Kauffmann TC, Fry NJ, Mansfield KD.

RNA Biol. 2017 Jul 3;14(7):938-951. doi: 10.1080/15476286.2017.1311456. Epub 2017 Mar 31.


The effect of angiotensin receptor neprilysin inhibitor, sacubitril/valsartan, on central nervous system amyloid-β concentrations and clearance in the cynomolgus monkey.

Schoenfeld HA, West T, Verghese PB, Holubasch M, Shenoy N, Kagan D, Buono C, Zhou W, DeCristofaro M, Douville J, Goodrich GG, Mansfield K, Saravanan C, Cumin F, Webb RL, Bateman RJ.

Toxicol Appl Pharmacol. 2017 May 15;323:53-65. doi: 10.1016/j.taap.2017.03.014. Epub 2017 Mar 15.


Japanese encephalitis virus infection, diagnosis and control in domestic animals.

Mansfield KL, Hernández-Triana LM, Banyard AC, Fooks AR, Johnson N.

Vet Microbiol. 2017 Mar;201:85-92. doi: 10.1016/j.vetmic.2017.01.014. Epub 2017 Jan 15. Review.


Serum creatinine elevation after renin-angiotensin system blockade and long term cardiorenal risks: cohort study.

Schmidt M, Mansfield KE, Bhaskaran K, Nitsch D, Sørensen HT, Smeeth L, Tomlinson LA.

BMJ. 2017 Mar 9;356:j791. doi: 10.1136/bmj.j791.


Expression and localization of pannexin-1 and CALHM1 in porcine bladder and their involvement in modulating ATP release.

Sana-Ur-Rehman H, Markus I, Moore KH, Mansfield KJ, Liu L.

Am J Physiol Regul Integr Comp Physiol. 2017 May 1;312(5):R763-R772. doi: 10.1152/ajpregu.00039.2016. Epub 2017 Mar 2.


Evaluation of the quality and health literacy demand of online renal diet information.

Lambert K, Mullan J, Mansfield K, Koukomous A, Mesiti L.

J Hum Nutr Diet. 2017 Oct;30(5):634-645. doi: 10.1111/jhn.12466. Epub 2017 Feb 16.


Tick-borne pathogens induce differential expression of genes promoting cell survival and host resistance in Ixodes ricinus cells.

Mansfield KL, Cook C, Ellis RJ, Bell-Sakyi L, Johnson N, Alberdi P, de la Fuente J, Fooks AR.

Parasit Vectors. 2017 Feb 15;10(1):81. doi: 10.1186/s13071-017-2011-1.


Validity of estimated prevalence of decreased kidney function and renal replacement therapy from primary care electronic health records compared with national survey and registry data in the United Kingdom.

Iwagami M, Tomlinson LA, Mansfield KE, Casula A, Caskey FJ, Aitken G, Fraser SDS, Roderick PJ, Nitsch D.

Nephrol Dial Transplant. 2017 Apr 1;32(suppl_2):ii142-ii150. doi: 10.1093/ndt/gfw318.


From the Cover: Drug-Induced Taste Disorders in Clinical Practice and Preclinical Safety Evaluation.

Wang T, Glendinning J, Grushka M, Hummel T, Mansfield K.

Toxicol Sci. 2017 Apr 1;156(2):315-324. doi: 10.1093/toxsci/kfw263. Review.


Adherence to guidelines for creatinine and potassium monitoring and discontinuation following renin-angiotensin system blockade: a UK general practice-based cohort study.

Schmidt M, Mansfield KE, Bhaskaran K, Nitsch D, Sørensen HT, Smeeth L, Tomlinson LA.

BMJ Open. 2017 Jan 9;7(1):e012818. doi: 10.1136/bmjopen-2016-012818. Erratum in: BMJ Open. 2017 Sep 18;7(9):e012818corr1.


Trehalose Glycopolymer Enhances Both Solution Stability and Pharmacokinetics of a Therapeutic Protein.

Liu Y, Lee J, Mansfield KM, Ko JH, Sallam S, Wesdemiotis C, Maynard HD.

Bioconjug Chem. 2017 Mar 15;28(3):836-845. doi: 10.1021/acs.bioconjchem.6b00659. Epub 2017 Jan 3.


Prescription of renin-angiotensin system blockers and risk of acute kidney injury: a population-based cohort study.

Mansfield KE, Nitsch D, Smeeth L, Bhaskaran K, Tomlinson LA.

BMJ Open. 2016 Dec 21;6(12):e012690. doi: 10.1136/bmjopen-2016-012690.


Rabies pre-exposure prophylaxis elicits long-lasting immunity in humans.

Mansfield KL, Andrews N, Goharriz H, Goddard T, McElhinney LM, Brown KE, Fooks AR.

Vaccine. 2016 Nov 21;34(48):5959-5967. doi: 10.1016/j.vaccine.2016.09.058. Epub 2016 Oct 27.


Partner Bereavement and Risk of Herpes Zoster: Results from Two Population-Based Case-Control Studies in Denmark and the United Kingdom.

Schmidt SA, Vestergaard M, Pedersen HS, Schønheyder HC, Thomas SL, Smeeth L, Mansfield KE, Sørensen HT, Forbes HJ, Langan SM.

Clin Infect Dis. 2017 Mar 1;64(5):572-579. doi: 10.1093/cid/ciw840.


Passive drift or active swimming in marine organisms?

Putman NF, Lumpkin R, Sacco AE, Mansfield KL.

Proc Biol Sci. 2016 Dec 14;283(1844). pii: 20161689.


Dynamics of Hydrogel-Assisted Giant Unilamellar Vesicle Formation from Unsaturated Lipid Systems.

Peruzzi J, Gutierrez MG, Mansfield K, Malmstadt N.

Langmuir. 2016 Dec 6;32(48):12702-12709. Epub 2016 Nov 14.


Comparative effectiveness of fourth-line anti-hypertensive agents in resistant hypertension: A systematic review and meta-analysis.

Sinnott SJ, Tomlinson LA, Root AA, Mathur R, Mansfield KE, Smeeth L, Douglas IJ.

Eur J Prev Cardiol. 2017 Feb;24(3):228-238. doi: 10.1177/2047487316675194. Epub 2016 Nov 19. Review.


Compound Property Optimization in Drug Discovery Using Quantitative Surface Sampling Micro Liquid Chromatography with Tandem Mass Spectrometry.

Chen X, Hatsis P, Judge J, Argikar UA, Ren X, Sarber J, Mansfield K, Liang G, Amaral A, Catoire A, Bentley A, Ramos L, Moench P, Hintermann S, Carcache D, Glick J, Flarakos J.

Anal Chem. 2016 Dec 6;88(23):11813-11820. Epub 2016 Nov 16.


Biomarkers reveal sea turtles remained in oiled areas following the Deepwater Horizon oil spill.

Vander Zanden HB, Bolten AB, Tucker AD, Hart KM, Lamont MM, Fujisaki I, Reich KJ, Addison DS, Mansfield KL, Phillips KF, Pajuelo M, Bjorndal KA.

Ecol Appl. 2016 Oct;26(7):2145-2155. doi: 10.1002/eap.1366. Epub 2016 Sep 23.


Identifying patients with chronic widespread pain in primary care.

Mansfield KE, Sim J, Croft P, Jordan KP.

Pain. 2017 Jan;158(1):110-119.


Supporting rabies control in India.

Mansfield KL, Banyard AC, Fooks AR, Franka R, Isloor S, Rahman A.

Vet Rec. 2016 Sep 24;179(12):296-7. doi: 10.1136/vr.i4687.


Antiviral Nucleotide Incorporation by Recombinant Human Mitochondrial RNA Polymerase Is Predictive of Increased In Vivo Mitochondrial Toxicity Risk.

Fenaux M, Lin X, Yokokawa F, Sweeney Z, Saunders O, Xie L, Lim SP, Uteng M, Uehara K, Warne R, Gang W, Jones C, Yendluri S, Gu H, Mansfield K, Boisclair J, Heimbach T, Catoire A, Bracken K, Weaver M, Moser H, Zhong W.

Antimicrob Agents Chemother. 2016 Nov 21;60(12):7077-7085. Print 2016 Dec.

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