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Anthropogenic Impacts on Mortality and Population Viability of the Monarch Butterfly.

Malcolm SB.

Annu Rev Entomol. 2018 Jan 7;63:277-302. doi: 10.1146/annurev-ento-020117-043241. Epub 2017 Oct 4.


Fab-dsFv: A bispecific antibody format with extended serum half-life through albumin binding.

Davé E, Adams R, Zaccheo O, Carrington B, Compson JE, Dugdale S, Airey M, Malcolm S, Hailu H, Wild G, Turner A, Heads J, Sarkar K, Ventom A, Marshall D, Jairaj M, Kopotsha T, Christodoulou L, Zamacona M, Lawson AD, Heywood S, Humphreys DP.

MAbs. 2016 Oct;8(7):1319-1335. Epub 2016 Aug 17.


Developing resources to facilitate culturally-sensitive service planning and delivery - doing research inclusively with people with learning disabilities.

Unwin G, Larkin M, Rose J, Kroese BS, Malcolm S.

Res Involv Engagem. 2016 May 18;2:17. doi: 10.1186/s40900-016-0031-1. eCollection 2016.


Whole USH2A Gene Sequencing Identifies Several New Deep Intronic Mutations.

Liquori A, Vaché C, Baux D, Blanchet C, Hamel C, Malcolm S, Koenig M, Claustres M, Roux AF.

Hum Mutat. 2016 Feb;37(2):184-93. doi: 10.1002/humu.22926. Epub 2015 Nov 23.


CDP7657, an anti-CD40L antibody lacking an Fc domain, inhibits CD40L-dependent immune responses without thrombotic complications: an in vivo study.

Shock A, Burkly L, Wakefield I, Peters C, Garber E, Ferrant J, Taylor FR, Su L, Hsu YM, Hutto D, Amirkhosravi A, Meyer T, Francis J, Malcolm S, Robinson M, Brown D, Shaw S, Foulkes R, Lawson A, Harari O, Bourne T, Maloney A, Weir N.

Arthritis Res Ther. 2015 Sep 3;17:234. doi: 10.1186/s13075-015-0757-4.


Nutritional Knowledge and Practices, Lifestyle Characteristics and Anthropometric Status of Turks and Caicos Islands Elementary School Children.

Maitland TE, Malcolm S, Handfield S.

West Indian Med J. 2015 Jan;64(1):29-36. doi: 10.7727/wimj.2015.111. Epub 2015 Apr 28.


Knowledge, attitudes and practices regarding cervical cancer and screening among Haitian health care workers.

Zahedi L, Sizemore E, Malcolm S, Grossniklaus E, Nwosu O.

Int J Environ Res Public Health. 2014 Nov 10;11(11):11541-52. doi: 10.3390/ijerph111111541.


Coastal Zone Ecosystem Services: from science to values and decision making; a case study.

Luisetti T, Turner RK, Jickells T, Andrews J, Elliott M, Schaafsma M, Beaumont N, Malcolm S, Burdon D, Adams C, Watts W.

Sci Total Environ. 2014 Sep 15;493:682-93. doi: 10.1016/j.scitotenv.2014.05.099. Epub 2014 Jul 1.


Enrichment of LOVD-USHbases with 152 USH2A genotypes defines an extensive mutational spectrum and highlights missense hotspots.

Baux D, Blanchet C, Hamel C, Meunier I, Larrieu L, Faugère V, Vaché C, Castorina P, Puech B, Bonneau D, Malcolm S, Claustres M, Roux AF.

Hum Mutat. 2014 Oct;35(10):1179-86. doi: 10.1002/humu.22608. Epub 2014 Jul 15.


Comparative safety and tolerability of duloxetine vs. pregabalin vs. duloxetine plus gabapentin in patients with diabetic peripheral neuropathic pain.

Irving G, Tanenberg RJ, Raskin J, Risser RC, Malcolm S.

Int J Clin Pract. 2014 Sep;68(9):1130-40. doi: 10.1111/ijcp.12452. Epub 2014 May 18.


Experience of targeted Usher exome sequencing as a clinical test.

Besnard T, García-García G, Baux D, Vaché C, Faugère V, Larrieu L, Léonard S, Millan JM, Malcolm S, Claustres M, Roux AF.

Mol Genet Genomic Med. 2014 Jan;2(1):30-43. doi: 10.1002/mgg3.25. Epub 2013 Jul 10.


A randomized, double-blind, placebo-controlled trial of duloxetine for the treatment of pain in patients with multiple sclerosis.

Vollmer TL, Robinson MJ, Risser RC, Malcolm SK.

Pain Pract. 2014 Nov;14(8):732-44. doi: 10.1111/papr.12127. Epub 2013 Oct 24.


The lack of influence of food and local alcoholic brew on the blood level of Mectizan(®) (ivermectin).

Homeida MM, Malcolm SB, ElTayeb AZ, Eversole RR, Elassad AS, Geary TG, Ali MM, Mackenzie CD.

Acta Trop. 2013 Aug;127(2):97-100. doi: 10.1016/j.actatropica.2013.03.019. Epub 2013 Apr 11.


The contribution of GPR98 and DFNB31 genes to a Spanish Usher syndrome type 2 cohort.

García-García G, Besnard T, Baux D, Vaché C, Aller E, Malcolm S, Claustres M, Millan JM, Roux AF.

Mol Vis. 2013;19:367-73. Epub 2013 Feb 13.


Ecodevelopmental and intrapersonal moderators of a family based preventive intervention for Hispanic youth: a latent profile analysis.

Prado G, Huang S, Cordova D, Malcolm S, Estrada Y, Cano N, Maldonado-Molina M, Bacio G, Rosen A, Pantin H, Brown CH.

Prev Sci. 2013 Jun;14(3):290-9. doi: 10.1007/s11121-012-0326-x.


A humanised mouse model of cytokine release: comparison of CD3-specific antibody fragments.

Malcolm SL, Smith EL, Bourne T, Shaw S.

J Immunol Methods. 2012 Oct 31;384(1-2):33-42. doi: 10.1016/j.jim.2012.07.001. Epub 2012 Jul 11.


Predicting condom use attitudes, norms, and control beliefs in Hispanic problem behavior youth: the effects of family functioning and parent-adolescent communication about sex on condom use.

Malcolm S, Huang S, Cordova D, Freitas D, Arzon M, Jimenez GL, Pantin H, Prado G.

Health Educ Behav. 2013 Aug;40(4):384-91. doi: 10.1177/1090198112440010. Epub 2012 May 4.


Non-USH2A mutations in USH2 patients.

Besnard T, Vaché C, Baux D, Larrieu L, Abadie C, Blanchet C, Odent S, Blanchet P, Calvas P, Hamel C, Dollfus H, Lina-Granade G, Lespinasse J, David A, Isidor B, Morin G, Malcolm S, Tuffery-Giraud S, Claustres M, Roux AF.

Hum Mutat. 2012 Mar;33(3):504-10. doi: 10.1002/humu.22004. Epub 2012 Jan 6.


Usher syndrome type 2 caused by activation of an USH2A pseudoexon: implications for diagnosis and therapy.

Vaché C, Besnard T, le Berre P, García-García G, Baux D, Larrieu L, Abadie C, Blanchet C, Bolz HJ, Millan J, Hamel C, Malcolm S, Claustres M, Roux AF.

Hum Mutat. 2012 Jan;33(1):104-8. doi: 10.1002/humu.21634. Epub 2011 Nov 16.


Effects of a family intervention in reducing HIV risk behaviors among high-risk Hispanic adolescents: a randomized controlled trial.

Prado G, Pantin H, Huang S, Cordova D, Tapia MI, Velazquez MR, Calfee M, Malcolm S, Arzon M, Villamar J, Jimenez GL, Cano N, Brown CH, Estrada Y.

Arch Pediatr Adolesc Med. 2012 Feb;166(2):127-33. doi: 10.1001/archpediatrics.2011.189. Epub 2011 Oct 3.


Audiological findings in 100 USH2 patients.

Abadie C, Blanchet C, Baux D, Larrieu L, Besnard T, Ravel P, Biboulet R, Hamel C, Malcolm S, Mondain M, Claustres M, Roux AF.

Clin Genet. 2012 Nov;82(5):433-8. doi: 10.1111/j.1399-0004.2011.01772.x. Epub 2011 Sep 30.


Synthesis and pharmacological characterization of bicyclic triple reuptake inhibitor 3-aryl octahydrocyclopenta[c]pyrrole analogues.

Shao L, Hewitt MC, Malcolm SC, Wang F, Ma J, Campbell UC, Spicer NA, Engel SR, Hardy LW, Jiang ZD, Schreiber R, Spear KL, Varney MA.

J Med Chem. 2011 Aug 11;54(15):5283-95. doi: 10.1021/jm101312a. Epub 2011 Jul 8.


Ownership and object history.

Friedman O, Neary KR, Defeyter MA, Malcolm SL.

New Dir Child Adolesc Dev. 2011 Summer;2011(132):79-89. doi: 10.1002/cd.298.


Primary, nonsyndromic vesicoureteric reflux and nephropathy in sibling pairs: a United Kingdom cohort for a DNA bank.

Lambert HJ, Stewart A, Gullett AM, Cordell HJ, Malcolm S, Feather SA, Goodship JA, Goodship TH, Woolf AS; UK VUR Study Group.

Clin J Am Soc Nephrol. 2011 Apr;6(4):760-6. doi: 10.2215/CJN.04580510. Epub 2011 Mar 24.


Four-year follow-up of diagnostic service in USH1 patients.

Roux AF, Faugère V, Vaché C, Baux D, Besnard T, Léonard S, Blanchet C, Hamel C, Mondain M, Gilbert-Dussardier B, Edery P, Lacombe D, Bonneau D, Holder-Espinasse M, Ambrosetti U, Journel H, David A, Lina-Granade G, Malcolm S, Claustres M.

Invest Ophthalmol Vis Sci. 2011 Jun 8;52(7):4063-71. doi: 10.1167/iovs.10-6869.


Discovery of N-methyl-1-(1-phenylcyclohexyl)ethanamine, a novel triple serotonin, norepinephrine and dopamine reuptake inhibitor.

Shao L, Hewitt MC, Wang F, Malcolm SC, Ma J, Campbell JE, Campbell UC, Engel SR, Spicer NA, Hardy LW, Schreiber R, Spear KL, Varney MA.

Bioorg Med Chem Lett. 2011 Mar 1;21(5):1434-7. doi: 10.1016/j.bmcl.2011.01.019. Epub 2011 Jan 12.


Discovery of N-methyl-1-(1-phenylcyclohexyl)methanamine, a novel triple serotonin, norepinephrine, and dopamine reuptake inhibitor.

Shao L, Hewitt MC, Wang F, Malcolm SC, Ma J, Campbell JE, Campbell UC, Engel SR, Spicer NA, Hardy LW, Schreiber R, Spear KL, Varney MA.

Bioorg Med Chem Lett. 2011 Mar 1;21(5):1438-41. doi: 10.1016/j.bmcl.2011.01.016. Epub 2011 Jan 12.


The Role of Attitudes, Family, Peer and School on Alcohol Use, Rule Breaking and Aggressive Behavior in Hispanic Delinquent Adolescents.

Cordova D, Huang S, Arzon M, Freitas D, Malcolm S, Prado G.

Open Fam Stud J. 2011;4(Suppl 1-M4):38-45.


Discovery of 1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydroquinolin-4-amine, a dual serotonin and dopamine reuptake inhibitor.

Shao L, Ma J, Wang F, Malcolm SC, Hewitt MC, Campbell UC, Spicer NA, Hardy LW, Schreiber R, Spear KL, Varney MA.

Bioorg Med Chem Lett. 2011 Jan 1;21(1):520-3. doi: 10.1016/j.bmcl.2010.10.086. Epub 2010 Oct 28.


Synthesis and pharmacological evaluation of 4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalenyl amines as triple reuptake inhibitors.

Shao L, Wang F, Malcolm SC, Ma J, Hewitt MC, Campbell UC, Bush LR, Spicer NA, Engel SR, Saraswat LD, Hardy LW, Koch P, Schreiber R, Spear KL, Varney MA.

Bioorg Med Chem. 2011 Jan 1;19(1):663-76. doi: 10.1016/j.bmc.2010.10.034. Epub 2010 Oct 21.


The long-term effects of childhood maltreatment experiences on subsequent illicit drug use and drug-related problems in young adulthood.

Huang S, Trapido E, Fleming L, Arheart K, Crandall L, French M, Malcolm S, Prado G.

Addict Behav. 2011 Jan-Feb;36(1-2):95-102. doi: 10.1016/j.addbeh.2010.09.001. Epub 2010 Sep 25.


Higher-order complexity through R-group effects in self-assembled tripeptide monolayers.

Rampulla DM, Oncel N, Malcolm SA, Bernasek SL.

Langmuir. 2010 Nov 2;26(21):16287-90. doi: 10.1021/la101413e.


Nasal epithelial cells are a reliable source to study splicing variants in Usher syndrome.

Vaché C, Besnard T, Blanchet C, Baux D, Larrieu L, Faugère V, Mondain M, Hamel C, Malcolm S, Claustres M, Roux AF.

Hum Mutat. 2010 Jun;31(6):734-41. doi: 10.1002/humu.21255.


Whole-genome linkage and association scan in primary, nonsyndromic vesicoureteric reflux.

Cordell HJ, Darlay R, Charoen P, Stewart A, Gullett AM, Lambert HJ, Malcolm S, Feather SA, Goodship TH, Woolf AS, Kenda RB, Goodship JA; UK VUR Study Group.

J Am Soc Nephrol. 2010 Jan;21(1):113-23. doi: 10.1681/ASN.2009060624. Epub 2009 Dec 3.


UMD-USHbases: a comprehensive set of databases to record and analyse pathogenic mutations and unclassified variants in seven Usher syndrome causing genes.

Baux D, Faugère V, Larrieu L, Le Guédard-Méreuze S, Hamroun D, Béroud C, Malcolm S, Claustres M, Roux AF.

Hum Mutat. 2008 Aug;29(8):E76-87. doi: 10.1002/humu.20780.


In vitro and in vivo evaluation of O-alkyl derivatives of tramadol.

Shao L, Hewitt M, Jerussi TP, Wu F, Malcolm S, Grover P, Fang K, Koch P, Senanayake C, Bhongle N, Ribe S, Bakale R, Currie M.

Bioorg Med Chem Lett. 2008 Mar 1;18(5):1674-80. doi: 10.1016/j.bmcl.2008.01.051. Epub 2008 Jan 18.


Effects of atomoxetine on attention-deficit/hyperactivity disorder in clinical pediatric treatment settings: a naturalistic study.

Bakken RJ, Paczkowski M, Kramer HP, Axelson AA, Williams DW, Malcolm SK, Sumner CR, Kelsey DK.

Curr Med Res Opin. 2008 Feb;24(2):449-60. doi: 10.1185/030079908X253627 .


Mutational analyses of UPIIIA, SHH, EFNB2 and HNF1beta in persistent cloaca and associated kidney malformations.

Jenkins D, Bitner-Glindzicz M, Thomasson L, Malcolm S, Warne SA, Feather SA, Flanagan SE, Ellard S, Bingham C, Santos L, Henkemeyer M, Zinn A, Baker LA, Wilcox DT, Woolf AS.

J Pediatr Urol. 2007 Feb;3(1):2-9.


Molecular and in silico analyses of the full-length isoform of usherin identify new pathogenic alleles in Usher type II patients.

Baux D, Larrieu L, Blanchet C, Hamel C, Ben Salah S, Vielle A, Gilbert-Dussardier B, Holder M, Calvas P, Philip N, Edery P, Bonneau D, Claustres M, Malcolm S, Roux AF.

Hum Mutat. 2007 Aug;28(8):781-9.


Large genomic rearrangements within the PCDH15 gene are a significant cause of USH1F syndrome.

Le Guédard S, Faugère V, Malcolm S, Claustres M, Roux AF.

Mol Vis. 2007 Jan 26;13:102-7.


Assessing the impact of nutrient enrichment in estuaries: susceptibility to eutrophication.

Painting SJ, Devlin MJ, Malcolm SJ, Parker ER, Mills DK, Mills C, Tett P, Wither A, Burt J, Jones R, Winpenny K.

Mar Pollut Bull. 2007;55(1-6):74-90. Epub 2006 Oct 9.


Mutation analyses of Uroplakin II in children with renal tract malformations.

Jenkins D, Bitner-Glindzicz M, Malcolm S, Allison J, de Bruyn R, Flanagan S, Thomas DF, Belk RA, Feather SA, Bingham C, Southgate J, Woolf AS.

Nephrol Dial Transplant. 2006 Dec;21(12):3415-21. Epub 2006 Sep 29.


Defining and detecting undesirable disturbance in the context of marine eutrophication.

Tett P, Gowen R, Mills D, Fernandes T, Gilpin L, Huxham M, Kennington K, Read P, Service M, Wilkinson M, Malcolm S.

Mar Pollut Bull. 2007;55(1-6):282-97. Epub 2006 Oct 2. Review.


Frameshift mutation in GJA12 leading to nystagmus, spastic ataxia and CNS dys-/demyelination.

Wolf NI, Cundall M, Rutland P, Rosser E, Surtees R, Benton S, Chong WK, Malcolm S, Ebinger F, Bitner-Glindzicz M, Woodward KJ.

Neurogenetics. 2007 Jan;8(1):39-44. Epub 2006 Sep 13.


Modelling potential impacts of bottom trawl fisheries on soft sediment biogeochemistry in the North Sea.

Duplisea DE, Jennings S, Malcolm SJ, Parker R, Sivyer DB.

Geochem Trans. 2001 Dec 19;2(1):112.


Survey of the frequency of USH1 gene mutations in a cohort of Usher patients shows the importance of cadherin 23 and protocadherin 15 genes and establishes a detection rate of above 90%.

Roux AF, Faugère V, Le Guédard S, Pallares-Ruiz N, Vielle A, Chambert S, Marlin S, Hamel C, Gilbert B, Malcolm S, Claustres M; French Usher Syndrome Collaboration.

J Med Genet. 2006 Sep;43(9):763-8. Epub 2006 May 5.


Heterogeneous duplications in patients with Pelizaeus-Merzbacher disease suggest a mechanism of coupled homologous and nonhomologous recombination.

Woodward KJ, Cundall M, Sperle K, Sistermans EA, Ross M, Howell G, Gribble SM, Burford DC, Carter NP, Hobson DL, Garbern JY, Kamholz J, Heng H, Hodes ME, Malcolm S, Hobson GM.

Am J Hum Genet. 2005 Dec;77(6):966-87. Epub 2005 Oct 19.


Mutation spectrum leading to an attenuated phenotype in dystrophinopathies.

Tuffery-Giraud S, Saquet C, Thorel D, Disset A, Rivier F, Malcolm S, Claustres M.

Eur J Hum Genet. 2005 Dec;13(12):1254-60.


De novo Uroplakin IIIa heterozygous mutations cause human renal adysplasia leading to severe kidney failure.

Jenkins D, Bitner-Glindzicz M, Malcolm S, Hu CC, Allison J, Winyard PJ, Gullett AM, Thomas DF, Belk RA, Feather SA, Sun TT, Woolf AS.

J Am Soc Nephrol. 2005 Jul;16(7):2141-9. Epub 2005 May 11.

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