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Items: 44


Coenzyme A-mediated degradation of pyruvate dehydrogenase kinase 4 promotes cardiac metabolic flexibility after high-fat feeding in mice.

Schafer C, Young ZT, Makarewich CA, Elnwasany A, Kinter CS, Kinter M, Szweda LI.

J Biol Chem. 2018 Mar 14. pii: jbc.RA117.000268. doi: 10.1074/jbc.RA117.000268. [Epub ahead of print]


Digital Ischemia After Application of Self-Adherent Elastic Wrap Dressing: A Case Series.

Makarewich CA, Lang P, Hutchinson DT.

Pediatrics. 2018 Jan;141(1). pii: e20163067. doi: 10.1542/peds.2016-3067. Epub 2017 Dec 7.


Findings Associated With Knee Pathology on MRI in Patients Without Osteoarthritis.

Wylie JD, Makarewich CA, Working ZM, Jacobson L, Schmidt RL, Crim JR, Burks RT.

J Am Acad Orthop Surg. 2017 Nov;25(11):780-786. doi: 10.5435/JAAOS-D-16-00797.


MED12 regulates a transcriptional network of calcium-handling genes in the heart.

Baskin KK, Makarewich CA, DeLeon SM, Ye W, Chen B, Beetz N, Schrewe H, Bassel-Duby R, Olson EN.

JCI Insight. 2017 Jul 20;2(14). pii: 91920. doi: 10.1172/jci.insight.91920. [Epub ahead of print]


Mining for Micropeptides.

Makarewich CA, Olson EN.

Trends Cell Biol. 2017 Sep;27(9):685-696. doi: 10.1016/j.tcb.2017.04.006. Epub 2017 May 18. Review.


Caveolae-localized L-type Ca2+ channels do not contribute to function or hypertrophic signalling in the mouse heart.

Correll RN, Makarewich CA, Zhang H, Zhang C, Sargent MA, York AJ, Berretta RM, Chen X, Houser SR, Molkentin JD.

Cardiovasc Res. 2017 Jun 1;113(7):749-759. doi: 10.1093/cvr/cvx046.


Widespread control of calcium signaling by a family of SERCA-inhibiting micropeptides.

Anderson DM, Makarewich CA, Anderson KM, Shelton JM, Bezprozvannaya S, Bassel-Duby R, Olson EN.

Sci Signal. 2016 Dec 6;9(457):ra119.


Tendon Transfers for Combined Peripheral Nerve Injuries.

Makarewich CA, Hutchinson DT.

Hand Clin. 2016 Aug;32(3):377-87. doi: 10.1016/j.hcl.2016.03.008. Epub 2016 May 2. Review.


The Medial Stitch in Transosseous-Equivalent Rotator Cuff Repair: Vertical or Horizontal Mattress?

Montanez A, Makarewich CA, Burks RT, Henninger HB.

Am J Sports Med. 2016 Sep;44(9):2225-30. doi: 10.1177/0363546516648680. Epub 2016 Jun 8.


A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy.

Davis J, Davis LC, Correll RN, Makarewich CA, Schwanekamp JA, Moussavi-Harami F, Wang D, York AJ, Wu H, Houser SR, Seidman CE, Seidman JG, Regnier M, Metzger JM, Wu JC, Molkentin JD.

Cell. 2016 May 19;165(5):1147-1159. doi: 10.1016/j.cell.2016.04.002. Epub 2016 Apr 21.


A peptide encoded by a transcript annotated as long noncoding RNA enhances SERCA activity in muscle.

Nelson BR, Makarewich CA, Anderson DM, Winders BR, Troupes CD, Wu F, Reese AL, McAnally JR, Chen X, Kavalali ET, Cannon SC, Houser SR, Bassel-Duby R, Olson EN.

Science. 2016 Jan 15;351(6270):271-5. doi: 10.1126/science.aad4076.


A mouse model for adult cardiac-specific gene deletion with CRISPR/Cas9.

Carroll KJ, Makarewich CA, McAnally J, Anderson DM, Zentilin L, Liu N, Giacca M, Bassel-Duby R, Olson EN.

Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):338-43. doi: 10.1073/pnas.1523918113. Epub 2015 Dec 30.


STIM1 elevation in the heart results in aberrant Ca²⁺ handling and cardiomyopathy.

Correll RN, Goonasekera SA, van Berlo JH, Burr AR, Accornero F, Zhang H, Makarewich CA, York AJ, Sargent MA, Chen X, Houser SR, Molkentin JD.

J Mol Cell Cardiol. 2015 Oct;87:38-47. doi: 10.1016/j.yjmcc.2015.07.032. Epub 2015 Aug 1.


Comparative effects of urocortins and stresscopin on cardiac myocyte contractility.

Makarewich CA, Troupes CD, Schumacher SM, Gross P, Koch WJ, Crandall DL, Houser SR.

J Mol Cell Cardiol. 2015 Sep;86:179-86. doi: 10.1016/j.yjmcc.2015.07.023. Epub 2015 Jul 29.


Autologous c-Kit+ Mesenchymal Stem Cell Injections Provide Superior Therapeutic Benefit as Compared to c-Kit+ Cardiac-Derived Stem Cells in a Feline Model of Isoproterenol-Induced Cardiomyopathy.

Taghavi S, Sharp TE 3rd, Duran JM, Makarewich CA, Berretta RM, Starosta T, Kubo H, Barbe M, Houser SR.

Clin Transl Sci. 2015 Oct;8(5):425-31. doi: 10.1111/cts.12251. Epub 2015 Feb 11.


A micropeptide encoded by a putative long noncoding RNA regulates muscle performance.

Anderson DM, Anderson KM, Chang CL, Makarewich CA, Nelson BR, McAnally JR, Kasaragod P, Shelton JM, Liou J, Bassel-Duby R, Olson EN.

Cell. 2015 Feb 12;160(4):595-606. doi: 10.1016/j.cell.2015.01.009. Epub 2015 Jan 29.


Platelet endothelial cell adhesion molecule-1 mediates endothelial-cardiomyocyte communication and regulates cardiac function.

McCormick ME, Collins C, Makarewich CA, Chen Z, Rojas M, Willis MS, Houser SR, Tzima E.

J Am Heart Assoc. 2015 Jan 19;4(1):e001210. doi: 10.1161/JAHA.114.001210.


Severe neurologic manifestations of fat embolism syndrome in a polytrauma patient.

Makarewich CA, Dwyer KW, Cantu RV.

Am J Orthop (Belle Mead NJ). 2015 Jan;44(1):E25-8.


GRK5-mediated exacerbation of pathological cardiac hypertrophy involves facilitation of nuclear NFAT activity.

Hullmann JE, Grisanti LA, Makarewich CA, Gao E, Gold JI, Chuprun JK, Tilley DG, Houser SR, Koch WJ.

Circ Res. 2014 Dec 5;115(12):976-85. doi: 10.1161/CIRCRESAHA.116.304475. Epub 2014 Oct 20.


β-adrenergic receptor-mediated cardiac contractility is inhibited via vasopressin type 1A-receptor-dependent signaling.

Tilley DG, Zhu W, Myers VD, Barr LA, Gao E, Li X, Song J, Carter RL, Makarewich CA, Yu D, Troupes CD, Grisanti LA, Coleman RC, Koch WJ, Houser SR, Cheung JY, Feldman AM.

Circulation. 2014 Nov 11;130(20):1800-11. doi: 10.1161/CIRCULATIONAHA.114.010434. Epub 2014 Sep 9.


Transient receptor potential channels contribute to pathological structural and functional remodeling after myocardial infarction.

Makarewich CA, Zhang H, Davis J, Correll RN, Trappanese DM, Hoffman NE, Troupes CD, Berretta RM, Kubo H, Madesh M, Chen X, Gao E, Molkentin JD, Houser SR.

Circ Res. 2014 Aug 29;115(6):567-580. doi: 10.1161/CIRCRESAHA.115.303831. Epub 2014 Jul 21.


Imatinib activates pathological hypertrophy by altering myocyte calcium regulation.

Barr LA, Makarewich CA, Berretta RM, Gao H, Troupes CD, Woitek F, Recchia F, Kubo H, Force T, Houser SR.

Clin Transl Sci. 2014 Oct;7(5):360-7. doi: 10.1111/cts.12173. Epub 2014 Jun 16.


The gut hormone ghrelin partially reverses energy substrate metabolic alterations in the failing heart.

Mitacchione G, Powers JC, Grifoni G, Woitek F, Lam A, Ly L, Settanni F, Makarewich CA, McCormick R, Trovato L, Houser SR, Granata R, Recchia FA.

Circ Heart Fail. 2014 Jul;7(4):643-51. doi: 10.1161/CIRCHEARTFAILURE.114.001167. Epub 2014 May 22.


Sorafenib cardiotoxicity increases mortality after myocardial infarction.

Duran JM, Makarewich CA, Trappanese D, Gross P, Husain S, Dunn J, Lal H, Sharp TE, Starosta T, Vagnozzi RJ, Berretta RM, Barbe M, Yu D, Gao E, Kubo H, Force T, Houser SR.

Circ Res. 2014 May 23;114(11):1700-1712. doi: 10.1161/CIRCRESAHA.114.303200. Epub 2014 Apr 9.


β-Adrenergic receptor-mediated transactivation of epidermal growth factor receptor decreases cardiomyocyte apoptosis through differential subcellular activation of ERK1/2 and Akt.

Grisanti LA, Talarico JA, Carter RL, Yu JE, Repas AA, Radcliffe SW, Tang HA, Makarewich CA, Houser SR, Tilley DG.

J Mol Cell Cardiol. 2014 Jul;72:39-51. doi: 10.1016/j.yjmcc.2014.02.009. Epub 2014 Feb 22.


Bone-derived stem cells repair the heart after myocardial infarction through transdifferentiation and paracrine signaling mechanisms.

Duran JM, Makarewich CA, Sharp TE, Starosta T, Zhu F, Hoffman NE, Chiba Y, Madesh M, Berretta RM, Kubo H, Houser SR.

Circ Res. 2013 Aug 16;113(5):539-52. doi: 10.1161/CIRCRESAHA.113.301202. Epub 2013 Jun 25.


T-type Ca²⁺ channels regulate the exit of cardiac myocytes from the cell cycle after birth.

Wang F, Gao H, Kubo H, Fan X, Zhang H, Berretta R, Chen X, Sharp T, Starosta T, Makarewich C, Li Y, Molkentin JD, Houser SR.

J Mol Cell Cardiol. 2013 Sep;62:122-30. doi: 10.1016/j.yjmcc.2013.05.016. Epub 2013 Jun 4.


Volume overload induces differential spatiotemporal regulation of myocardial soluble guanylyl cyclase in eccentric hypertrophy and heart failure.

Liu Y, Dillon AR, Tillson M, Makarewich C, Nguyen V, Dell'Italia L, Sabri AK, Rizzo V, Tsai EJ.

J Mol Cell Cardiol. 2013 Jul;60:72-83. doi: 10.1016/j.yjmcc.2013.03.019. Epub 2013 Apr 6.


Cardiotoxic and cardioprotective features of chronic β-adrenergic signaling.

Zhang X, Szeto C, Gao E, Tang M, Jin J, Fu Q, Makarewich C, Ai X, Li Y, Tang A, Wang J, Gao H, Wang F, Ge XJ, Kunapuli SP, Zhou L, Zeng C, Xiang KY, Chen X.

Circ Res. 2013 Feb 1;112(3):498-509. doi: 10.1161/CIRCRESAHA.112.273896. Epub 2012 Oct 25.


A characterization and targeting of the infarct border zone in a swine model of myocardial infarction.

Duran JM, Taghavi S, Berretta RM, Makarewich CA, Sharp Iii T, Starosta T, Udeshi F, George JC, Kubo H, Houser SR.

Clin Transl Sci. 2012 Oct;5(5):416-21. doi: 10.1111/j.1752-8062.2012.00432.x. Epub 2012 Jun 26.


Ca(2+) influx through L-type Ca(2+) channels and transient receptor potential channels activates pathological hypertrophy signaling.

Gao H, Wang F, Wang W, Makarewich CA, Zhang H, Kubo H, Berretta RM, Barr LA, Molkentin JD, Houser SR.

J Mol Cell Cardiol. 2012 Nov;53(5):657-67. doi: 10.1016/j.yjmcc.2012.08.005. Epub 2012 Aug 21.


Limitation of individual folding resources in the ER leads to outcomes distinct from the unfolded protein response.

Eletto D, Maganty A, Eletto D, Dersh D, Makarewich C, Biswas C, Paton JC, Paton AW, Doroudgar S, Glembotski CC, Argon Y.

J Cell Sci. 2012 Oct 15;125(Pt 20):4865-75. doi: 10.1242/jcs.108928. Epub 2012 Aug 1.


Deletion of muscle GRP94 impairs both muscle and body growth by inhibiting local IGF production.

Barton ER, Park S, James JK, Makarewich CA, Philippou A, Eletto D, Lei H, Brisson B, Ostrovsky O, Li Z, Argon Y.

FASEB J. 2012 Sep;26(9):3691-702. doi: 10.1096/fj.11-203026. Epub 2012 May 30.


Validation of transcatheter left ventricular electromechanical mapping for assessment of cardiac function and targeted transendocardial injection in a porcine ischemia-reperfusion model.

Taghavi S, Duran JM, Berretta RM, Makarewich CA, Udeshi F, Sharp TE, Kubo H, Houser SR, George JC.

Am J Transl Res. 2012;4(2):240-6. Epub 2012 Apr 18.


A caveolae-targeted L-type Ca²+ channel antagonist inhibits hypertrophic signaling without reducing cardiac contractility.

Makarewich CA, Correll RN, Gao H, Zhang H, Yang B, Berretta RM, Rizzo V, Molkentin JD, Houser SR.

Circ Res. 2012 Mar 2;110(5):669-74. doi: 10.1161/CIRCRESAHA.111.264028. Epub 2012 Feb 2.


Hyperphosphorylation of the cardiac ryanodine receptor at serine 2808 is not involved in cardiac dysfunction after myocardial infarction.

Zhang H, Makarewich CA, Kubo H, Wang W, Duran JM, Li Y, Berretta RM, Koch WJ, Chen X, Gao E, Valdivia HH, Houser SR.

Circ Res. 2012 Mar 16;110(6):831-40. doi: 10.1161/CIRCRESAHA.111.255158. Epub 2012 Feb 2.


Charles Bonnet syndrome-induced psychosis? Visual hallucinations with paranoid delusions in a visually-impaired man.

Makarewich C, West DA.

J Neuropsychiatry Clin Neurosci. 2011 Fall;23(4):E6. doi: 10.1176/jnp.23.4.jnpe6. No abstract available. Erratum in: J Neuropsychiatry Clin Neurosci. 2012 Dec 1;24(1):118.


Glucose regulated protein 94 is required for muscle differentiation through its control of the autocrine production of insulin-like growth factors.

Ostrovsky O, Eletto D, Makarewich C, Barton ER, Argon Y.

Biochim Biophys Acta. 2010 Feb;1803(2):333-41. doi: 10.1016/j.bbamcr.2009.11.005. Epub 2009 Nov 13.


Isolation and characterization of microsatellite markers from the acacia-ant Crematogaster mimosae.

Rubin BE, Makarewich CA, Talaba AL, Stenzler L, Bogdanowicz SM, Lovette IJ.

Mol Ecol Resour. 2009 Jul;9(4):1212-4. doi: 10.1111/j.1755-0998.2009.02614.x. Epub 2009 Mar 4.


An essential role for ATP binding and hydrolysis in the chaperone activity of GRP94 in cells.

Ostrovsky O, Makarewich CA, Snapp EL, Argon Y.

Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11600-5. doi: 10.1073/pnas.0902626106. Epub 2009 Jun 24.


Isolation and characterization of microsatellite markers from three species of swallows in the genus Tachycineta: T. albilinea, T. bicolor and T. leucorrhoa.

Makarewich CA, Stenzler LM, Ferretti V, Winkler DW, Lovette IJ.

Mol Ecol Resour. 2009 Mar;9(2):631-5. doi: 10.1111/j.1755-0998.2008.02484.x. Epub 2009 Jan 16.


Isolation and characterization of SNP variation at 90 anonymous loci in the banded wren (Thryothorus pleurostictus).

Cramer ER, Stenzler L, Talaba AL, Makarewich CA, Vehrencamp SL, Lovette IJ.

Conserv Genet. 2008 Dec;9(6):1657-1660.


Congruent population structure inferred from dispersal behaviour and intensive genetic surveys of the threatened Florida scrub-jay (Aphelocoma coerulescens).

Coulon A, Fitzpatrick JW, Bowman R, Stith BM, Makarewich CA, Stenzler LM, Lovette IJ.

Mol Ecol. 2008 Apr;17(7):1685-701. doi: 10.1111/j.1365-294X.2008.03705.x.


The peptide-binding activity of GRP94 is regulated by calcium.

Biswas C, Ostrovsky O, Makarewich CA, Wanderling S, Gidalevitz T, Argon Y.

Biochem J. 2007 Jul 15;405(2):233-41.

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