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Items: 1 to 50 of 1260

1.

High-Nuclearity Heterometallic tert-Butylethynide Clusters Assembled with tert-Butylphosphonate.

Xie YP, Duan GX, Jin JL, Bao LP, Lu X, Mak TCW.

Chemistry. 2018 Feb 22. doi: 10.1002/chem.201705906. [Epub ahead of print]

PMID:
29473225
2.

A COMPLEX ROLE FOR LIPOCALIN 2 IN BONE METABOLISM: GLOBAL ABLATION IN MICE INDUCES OSTEOPENIA CAUSED BY AN ALTERED ENERGY METABOLISM.

Capulli M, Ponzetti M, Maurizi A, Gemini-Piperni S, Berger T, Mak TW, Teti A, Rucci N.

J Bone Miner Res. 2018 Feb 14. doi: 10.1002/jbmr.3406. [Epub ahead of print]

PMID:
29444358
3.

Fragment-Based Screening of a Natural Product Library against 62 Potential Malaria Drug Targets Employing Native Mass Spectrometry.

Vu H, Pedro L, Mak T, McCormick B, Rowley J, Liu M, Di Capua A, Williams-Noonan B, Pham NB, Pouwer RH, Nguyen B, Andrews KT, Skinner-Adams T, Kim J, Hol WGJ, Hui R, Crowther GJ, Van Voorhis WC, Quinn RJ.

ACS Infect Dis. 2018 Feb 13. doi: 10.1021/acsinfecdis.7b00197. [Epub ahead of print]

PMID:
29436819
4.

Polo-like kinase 4 inhibition produces polyploidy and apoptotic death of lung cancers.

Kawakami M, Mustachio LM, Zheng L, Chen Y, Rodriguez-Canales J, Mino B, Kurie JM, Roszik J, Villalobos PA, Thu KL, Silvester J, Cescon DW, Wistuba II, Mak TW, Liu X, Dmitrovsky E.

Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1913-1918. doi: 10.1073/pnas.1719760115. Epub 2018 Feb 6.

PMID:
29434041
5.

Disruption of the anaphase-promoting complex confers resistance to TTK inhibitors in triple-negative breast cancer.

Thu KL, Silvester J, Elliott MJ, Ba-Alawi W, Duncan MH, Elia AC, Mer AS, Smirnov P, Safikhani Z, Haibe-Kains B, Mak TW, Cescon DW.

Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1570-E1577. doi: 10.1073/pnas.1719577115. Epub 2018 Jan 29.

PMID:
29378962
6.

Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes.

Song E, Ramos SV, Huang X, Liu Y, Botta A, Sung HK, Turnbull PC, Wheeler MB, Berger T, Wilson DJ, Perry CGR, Mak TW, Sweeney G.

Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1576-1581. doi: 10.1073/pnas.1720570115. Epub 2018 Jan 29.

PMID:
29378951
7.

iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling.

Qing X, Chinenov Y, Redecha P, Madaio M, Roelofs JJ, Farber G, Issuree PD, Donlin L, McIlwain DR, Mak TW, Blobel CP, Salmon JE.

J Clin Invest. 2018 Jan 25. pii: 97650. doi: 10.1172/JCI97650. [Epub ahead of print]

8.

Author Correction: Gene isoforms as expression-based biomarkers predictive of drug response in vitro.

Safikhani Z, Smirnov P, Thu KL, Silvester J, El-Hachem N, Quevedo R, Lupien M, Mak TW, Cescon D, Haibe-Kains B.

Nat Commun. 2018 Jan 9;9(1):166. doi: 10.1038/s41467-017-02136-5.

9.

Atomically Precise Site-Specific Tailoring and Directional Assembly of Superatomic Silver Nanoclusters.

Wang ZY, Wang MQ, Li YL, Luo P, Jia TT, Huang RW, Zang SQ, Mak TCW.

J Am Chem Soc. 2018 Jan 24;140(3):1069-1076. doi: 10.1021/jacs.7b11338. Epub 2018 Jan 10.

PMID:
29297682
10.

Cardiac-specific ablation of the E3 ubiquitin ligase Mdm2 leads to oxidative stress, broad mitochondrial deficiency and early death.

Hauck L, Stanley-Hasnain S, Fung A, Grothe D, Rao V, Mak TW, Billia F.

PLoS One. 2017 Dec 21;12(12):e0189861. doi: 10.1371/journal.pone.0189861. eCollection 2017.

11.

Loss of 5-hydroxymethylcytosine is a frequent event in Peripheral T cell lymphomas.

Lemonnier F, Poullot E, Dupuy A, Couronné L, Martin N, Scourzic L, Fataccioli V, Bruneau J, Cairns RA, Mak TW, Bernard OA, de Leval L, Gaulard P.

Haematologica. 2017 Dec 14. pii: haematol.2017.167973. doi: 10.3324/haematol.2017.167973. [Epub ahead of print] No abstract available.

12.

Lipocalin-2 in Fructose-Induced Fatty Liver Disease.

Lambertz J, Berger T, Mak TW, van Helden J, Weiskirchen R.

Front Physiol. 2017 Nov 28;8:964. doi: 10.3389/fphys.2017.00964. eCollection 2017.

13.

2-oxo-PCE: ketamine analogue on the streets.

Chong YK, Tang MH, Chan CL, Li YK, Ching CK, Mak TW.

Hong Kong Med J. 2017 Dec;23(6):665-6. doi: 10.12809/hkmj177089. No abstract available.

PMID:
29226843
14.

Fundamental movement skills and balance of children with Down syndrome.

Capio CM, Mak TCT, Tse MA, Masters RSW.

J Intellect Disabil Res. 2018 Mar;62(3):225-236. doi: 10.1111/jir.12458. Epub 2017 Dec 5.

PMID:
29205624
15.

Pillars Article: Requirement for the Transcription Factor LSIRF/IRF4 for Mature B and T Lymphocyte Function. Science. 1997. 275: 540-543.

Mittrücker HW, Matsuyama T, Grossman A, Kündig TM, Potter J, Shahinian A, Wakeham A, Patterson B, Ohashi PS, Mak TW.

J Immunol. 2017 Dec 1;199(11):3717-3720. No abstract available.

PMID:
29158347
16.

Tumor Necrosis Factor-Mediated Survival of CD169+ Cells Promotes Immune Activation during Vesicular Stomatitis Virus Infection.

Shinde PV, Xu HC, Maney SK, Kloetgen A, Namineni S, Zhuang Y, Honke N, Shaabani N, Bellora N, Doerrenberg M, Trilling M, Pozdeev VI, van Rooijen N, Scheu S, Pfeffer K, Crocker PR, Tanaka M, Duggimpudi S, Knolle P, Heikenwalder M, Ruland J, Mak TW, Brenner D, Pandyra AA, Hoell JI, Borkhardt A, Häussinger D, Lang KS, Lang PA.

J Virol. 2018 Jan 17;92(3). pii: e01637-17. doi: 10.1128/JVI.01637-17. Print 2018 Feb 1.

17.

Glycogen Synthase Kinase-3 Modulates Cbl-b and Constrains T Cell Activation.

Tran CW, Saibil SD, Le Bihan T, Hamilton SR, Lang KS, You H, Lin AE, Garza KM, Elford AR, Tai K, Parsons ME, Wigmore K, Vainberg MG, Penninger JM, Woodgett JR, Mak TW, Ohashi PS.

J Immunol. 2017 Dec 15;199(12):4056-4065. doi: 10.4049/jimmunol.1600396. Epub 2017 Nov 6.

PMID:
29109121
18.

Temperature-Mediated Template Release: Facile Growth of Copper(I) Mixed Ethynediide/Isopropylethynide Nanoclusters.

Zhang LL, Mak TCW.

Angew Chem Int Ed Engl. 2017 Dec 18;56(51):16228-16232. doi: 10.1002/anie.201708760. Epub 2017 Nov 22.

PMID:
29105930
19.

Gene isoforms as expression-based biomarkers predictive of drug response in vitro.

Safikhani Z, Smirnov P, Thu KL, Silvester J, El-Hachem N, Quevedo R, Lupien M, Mak TW, Cescon D, Haibe-Kains B.

Nat Commun. 2017 Oct 24;8(1):1126. doi: 10.1038/s41467-017-01153-8. Erratum in: Nat Commun. 2018 Jan 9;9(1):166.

20.

DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory Bowel Diseases Differentiate Disease Subtypes and Associate With Outcome.

Howell KJ, Kraiczy J, Nayak KM, Gasparetto M, Ross A, Lee C, Mak TN, Koo BK, Kumar N, Lawley T, Sinha A, Rosenstiel P, Heuschkel R, Stegle O, Zilbauer M.

Gastroenterology. 2018 Feb;154(3):585-598. doi: 10.1053/j.gastro.2017.10.007. Epub 2017 Oct 12.

21.

Assembly of high-symmetry silver(i) alkyl-1,3-diynyl cluster complexes via core transformation.

Hau SCK, Mak TCW.

Dalton Trans. 2017 Oct 24;46(41):14098-14101. doi: 10.1039/c7dt03406g.

PMID:
29022604
22.

Adulteration of proprietary Chinese medicines and health products with undeclared drugs: experience of a tertiary toxicology laboratory in Hong Kong.

Ching CK, Chen SPL, Lee HHC, Lam YH, Ng SW, Chen ML, Tang MHY, Chan SSS, Ng CWY, Cheung JWL, Chan TYC, Lau NKC, Chong YK, Mak TWL.

Br J Clin Pharmacol. 2018 Jan;84(1):172-178. doi: 10.1111/bcp.13420. Epub 2017 Oct 4.

PMID:
28965348
23.

Silver Thiolate Nano-sized Molecular Clusters and Their Supramolecular Covalent Frameworks: An Approach Toward Pre-templated Synthesis.

Chen ZY, Tam DYS, Zhang LL, Mak TCW.

Chem Asian J. 2017 Oct 18;12(20):2763-2769. doi: 10.1002/asia.201701150. Epub 2017 Sep 26.

PMID:
28914496
24.

Bcl10 synergistically links CEACAM3 and TLR-dependent inflammatory signalling.

Sintsova A, Guo CX, Sarantis H, Mak TW, Glogauer M, Gray-Owen SD.

Cell Microbiol. 2018 Jan;20(1). doi: 10.1111/cmi.12788. Epub 2017 Oct 9.

PMID:
28886618
25.

Check point inhibitors as therapies for infectious diseases.

Cox MA, Nechanitzky R, Mak TW.

Curr Opin Immunol. 2017 Oct;48:61-67. doi: 10.1016/j.coi.2017.07.016. Epub 2017 Aug 31. Review.

PMID:
28865357
26.

A Serum Small Molecule Biosignature of Radiation Exposure from Total Body Irradiated Patients.

Laiakis EC, Pannkuk EL, Chauthe SK, Wang YW, Lian M, Mak TD, Barker CA, Astarita G, Fornace AJ Jr.

J Proteome Res. 2017 Oct 6;16(10):3805-3815. doi: 10.1021/acs.jproteome.7b00468. Epub 2017 Aug 31.

PMID:
28825479
27.

Structure-Directing Role of Phosphonate in the Synthesis of High-Nuclearity Silver(I) Sulfide-Ethynide-Thiolate Clusters.

Jin JL, Xie YP, Cui H, Duan GX, Lu X, Mak TCW.

Inorg Chem. 2017 Sep 5;56(17):10412-10417. doi: 10.1021/acs.inorgchem.7b01326. Epub 2017 Aug 15.

PMID:
28809553
28.

Inhibition of the spindle assembly checkpoint kinase Mps-1 as a novel therapeutic strategy in malignant mesothelioma.

Szymiczek A, Carbone M, Pastorino S, Napolitano A, Tanji M, Minaai M, Pagano I, Mason JM, Pass HI, Bray MR, Mak TW, Yang H.

Oncogene. 2017 Nov 16;36(46):6501-6507. doi: 10.1038/onc.2017.266. Epub 2017 Jul 31.

29.

p53 and Mdm2 act synergistically to maintain cardiac homeostasis and mediate cardiomyocyte cell cycle arrest through a network of microRNAs.

Stanley-Hasnain S, Hauck L, Grothe D, Aschar-Sobbi R, Beca S, Butany J, Backx PH, Mak TW, Billia F.

Cell Cycle. 2017;16(17):1585-1600. doi: 10.1080/15384101.2017.1346758. Epub 2017 Jul 26.

PMID:
28745540
30.

Robotic transanal surgery (RTAS) with utilization of a next-generation single-port system: a cadaveric feasibility study.

Marks J, Ng S, Mak T.

Tech Coloproctol. 2017 Jul;21(7):541-545. doi: 10.1007/s10151-017-1655-3. Epub 2017 Jul 14.

PMID:
28707106
31.

The xenoestrogens biphenol-A and nonylphenol differentially regulate metalloprotease-mediated shedding of EGFR ligands.

Urriola-Muñoz P, Li X, Maretzky T, McIlwain DR, Mak TW, Reyes JG, Blobel CP, Moreno RD.

J Cell Physiol. 2018 Mar;233(3):2247-2256. doi: 10.1002/jcp.26097. Epub 2017 Aug 25.

PMID:
28703301
32.

Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function.

Lee YH, Martin-Orozco N, Zheng P, Li J, Zhang P, Tan H, Park HJ, Jeong M, Chang SH, Kim BS, Xiong W, Zang W, Guo L, Liu Y, Dong ZJ, Overwijk WW, Hwu P, Yi Q, Kwak L, Yang Z, Mak TW, Li W, Radvanyi LG, Ni L, Liu D, Dong C.

Cell Res. 2017 Aug;27(8):1034-1045. doi: 10.1038/cr.2017.90. Epub 2017 Jul 7.

PMID:
28685773
33.

Lipocalin-2 induces NLRP3 inflammasome activation via HMGB1 induced TLR4 signaling in heart tissue of mice under pressure overload challenge.

Song E, Jahng JW, Chong LP, Sung HK, Han M, Luo C, Wu D, Boo S, Hinz B, Cooper MA, Robertson AA, Berger T, Mak TW, George I, Schulze PC, Wang Y, Xu A, Sweeney G.

Am J Transl Res. 2017 Jun 15;9(6):2723-2735. eCollection 2017.

35.

Hypersensitive dual-function luminescence switching of a silver-chalcogenolate cluster-based metal-organic framework.

Huang RW, Wei YS, Dong XY, Wu XH, Du CX, Zang SQ, Mak TCW.

Nat Chem. 2017 Jul;9(7):689-697. doi: 10.1038/nchem.2718. Epub 2017 Feb 13.

PMID:
28644463
36.

Glutathione Primes T Cell Metabolism for Inflammation.

Mak TW, Grusdat M, Duncan GS, Dostert C, Nonnenmacher Y, Cox M, Binsfeld C, Hao Z, Brüstle A, Itsumi M, Jäger C, Chen Y, Pinkenburg O, Camara B, Ollert M, Bindslev-Jensen C, Vasiliou V, Gorrini C, Lang PA, Lohoff M, Harris IS, Hiller K, Brenner D.

Immunity. 2017 Jun 20;46(6):1089-1090. doi: 10.1016/j.immuni.2017.06.009. No abstract available.

PMID:
28636957
37.

A cross-clade H5N1 influenza A virus neutralizing monoclonal antibody binds to a novel epitope within the vestigial esterase domain of hemagglutinin.

Paul SS, Mok CK, Mak TM, Ng OW, Aboagye JO, Wohlbold TJ, Krammer F, Tan YJ.

Antiviral Res. 2017 Aug;144:299-310. doi: 10.1016/j.antiviral.2017.06.012. Epub 2017 Jun 19.

PMID:
28633988
38.

A Sensitive Method for Detecting Zika Virus Antigen in Patients' Whole-Blood Specimens as an Alternative Diagnostic Approach.

Lum FM, Lin C, Susova OY, Teo TH, Fong SW, Mak TM, Lee LK, Chong CY, Lye DCB, Lin RTP, Merits A, Leo YS, Ng LFP.

J Infect Dis. 2017 Jul 15;216(2):182-190. doi: 10.1093/infdis/jix276.

PMID:
28586426
39.

2-HG Inhibits Necroptosis by Stimulating DNMT1-Dependent Hypermethylation of the RIP3 Promoter.

Yang Z, Jiang B, Wang Y, Ni H, Zhang J, Xia J, Shi M, Hung LM, Ruan J, Mak TW, Li Q, Han J.

Cell Rep. 2017 May 30;19(9):1846-1857. doi: 10.1016/j.celrep.2017.05.012.

40.

Angioimmunoblastic T-cell lymphoma: more than a disease of T follicular helper cells.

Lemonnier F, Mak TW.

J Pathol. 2017 Aug;242(4):387-390. doi: 10.1002/path.4920. Epub 2017 Jun 29.

PMID:
28543514
41.

Polygenic scores via penalized regression on summary statistics.

Mak TSH, Porsch RM, Choi SW, Zhou X, Sham PC.

Genet Epidemiol. 2017 Sep;41(6):469-480. doi: 10.1002/gepi.22050. Epub 2017 May 8.

PMID:
28480976
42.

Fire and water: Tumor cell adaptation to metabolic conditions.

Cairns RA, Mak TW.

Exp Cell Res. 2017 Jul 15;356(2):204-208. doi: 10.1016/j.yexcr.2017.04.029. Epub 2017 Apr 27. Review.

PMID:
28457987
43.

Role of phosphatase and tensin homolog in hypoxic pulmonary vasoconstriction.

Krauszman A, Mak TW, Szaszi K, Kuebler WM.

Cardiovasc Res. 2017 Jul 1;113(8):869-878. doi: 10.1093/cvr/cvx076.

PMID:
28430879
44.

Glutathione Primes T Cell Metabolism for Inflammation.

Mak TW, Grusdat M, Duncan GS, Dostert C, Nonnenmacher Y, Cox M, Binsfeld C, Hao Z, Brüstle A, Itsumi M, Jäger C, Chen Y, Pinkenburg O, Camara B, Ollert M, Bindslev-Jensen C, Vasiliou V, Gorrini C, Lang PA, Lohoff M, Harris IS, Hiller K, Brenner D.

Immunity. 2017 Apr 18;46(4):675-689. doi: 10.1016/j.immuni.2017.03.019. Erratum in: Immunity. 2017 Jun 20;46(6):1089-1090.

PMID:
28423341
45.

IDH1 Mutation Promotes Tumorigenesis by Inhibiting JNK Activation and Apoptosis Induced by Serum Starvation.

Jiang B, Zhang J, Xia J, Zhao W, Wu Y, Shi M, Luo L, Zhou H, Chen A, Ma H, Zhao Q, Suleman M, Lin F, Zhou L, Wang J, Zhang Y, He Y, Li X, Hung LM, Mak TW, Li Q.

Cell Rep. 2017 Apr 11;19(2):389-400. doi: 10.1016/j.celrep.2017.03.053.

46.

Altered mitochondrial and peroxisomal integrity in lipocalin-2-deficient mice with hepatic steatosis.

Asimakopoulou A, Fülöp A, Borkham-Kamphorst E, de Leur EV, Gassler N, Berger T, Beine B, Meyer HE, Mak TW, Hopf C, Henkel C, Weiskirchen R.

Biochim Biophys Acta. 2017 Sep;1863(9):2093-2110. doi: 10.1016/j.bbadis.2017.04.006. Epub 2017 Apr 7.

PMID:
28396286
47.

Supraventricular tachycardia and acute confusion following ingestion of e-cigarette fluid containing AB-FUBINACA and ADB-FUBINACA: a case report with quantitative analysis of serum drug concentrations.

Lam RPK, Tang MHY, Leung SC, Chong YK, Tsui MSH, Mak TWL.

Clin Toxicol (Phila). 2017 Aug;55(7):662-667. doi: 10.1080/15563650.2017.1307385. Epub 2017 Apr 10.

PMID:
28393558
48.

Rapid Identification of Pathogenic Variants in Two Cases of Charcot-Marie-Tooth Disease by Gene-Panel Sequencing.

Ho CC, Tai SM, Lee EC, Mak TS, Liu TK, Tang VW, Poon WT.

Int J Mol Sci. 2017 Apr 5;18(4). pii: E770. doi: 10.3390/ijms18040770.

49.

Data on IL-10R neutralization-induced chronic colitis in Lipocalin 2 deficient mice on BALB/c background.

Singh V, Yeoh BS, Nilsen-Hamilton M, Berger T, Mak TW, Vijay-Kumar M.

Data Brief. 2017 Mar 8;11:588-592. doi: 10.1016/j.dib.2017.03.002. eCollection 2017 Apr.

50.

MOB1-YAP1/TAZ-NKX2.1 axis controls bronchioalveolar cell differentiation, adhesion and tumour formation.

Otsubo K, Goto H, Nishio M, Kawamura K, Yanagi S, Nishie W, Sasaki T, Maehama T, Nishina H, Mimori K, Nakano T, Shimizu H, Mak TW, Nakao K, Nakanishi Y, Suzuki A.

Oncogene. 2017 Jul 20;36(29):4201-4211. doi: 10.1038/onc.2017.58. Epub 2017 Mar 27.

PMID:
28346423

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