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DNMTi/HDACi combined epigenetic targeted treatment induces reprogramming of myeloma cells in the direction of normal plasma cells.

Bruyer A, Maes K, Herviou L, Kassambara A, Seckinger A, Cartron G, Rème T, Robert N, Requirand G, Boireau S, Müller-Tidow C, Veyrune JL, Vincent L, Bouhya S, Goldschmidt H, Vanderkerken K, Hose D, Klein B, De Bruyne E, Moreaux J.

Br J Cancer. 2018 Mar 2. doi: 10.1038/s41416-018-0025-x. [Epub ahead of print]


Volunteers in Ethiopia's women's development army are more deprived and distressed than their neighbors: cross-sectional survey data from rural Ethiopia.

Maes K, Closser S, Tesfaye Y, Gilbert Y, Abesha R.

BMC Public Health. 2018 Feb 14;18(1):258. doi: 10.1186/s12889-018-5159-5.


Pharmaceutical interventions on prescribed medicines in community pharmacies: focus on patient-reported problems.

Maes KA, Hersberger KE, Lampert ML.

Int J Clin Pharm. 2018 Feb 5. doi: 10.1007/s11096-018-0595-y. [Epub ahead of print]


ENDOR-Induced EPR of Disordered Systems: Application to X-Irradiated Alanine.

Kusakovskij J, Maes K, Callens F, Vrielinck H.

J Phys Chem A. 2018 Feb 15;122(6):1756-1763. doi: 10.1021/acs.jpca.7b11804. Epub 2018 Feb 6.


Loss of RASSF4 expression in multiple myeloma promotes RAS-driven malignant progression.

De Smedt E, Maes K, Verhulst S, Liu H, Kassambara A, Maes A, Robert N, Heirman C, Cakana A, Hose D, Breckpot K, van Grunsven LA, De Veirman K, Menu E, Vanderkerken K, Moreaux J, De Bruyne E.

Cancer Res. 2017 Dec 19. pii: canres.1544.2017. doi: 10.1158/0008-5472.CAN-17-1544. [Epub ahead of print]


The therapeutic potential of cell cycle targeting in multiple myeloma.

Maes A, Menu E, Veirman K, Maes K, Vand Erkerken K, De Bruyne E.

Oncotarget. 2017 Jun 28;8(52):90501-90520. doi: 10.18632/oncotarget.18765. eCollection 2017 Oct 27. Review.


Documentation of pharmaceutical care: Validation of an intervention oriented classification system.

Maes KA, Studer H, Berger J, Hersberger KE, Lampert ML.

J Eval Clin Pract. 2017 Dec;23(6):1425-1432. doi: 10.1111/jep.12817. Epub 2017 Sep 29.


Robot-assisted brachytherapy of the bladder with long distance support using video conferencing.

Mascarenhas F, Maes K, Marques F, Formoso R, Antunes T.

J Contemp Brachytherapy. 2017 Aug;9(4):375-382. doi: 10.5114/jcb.2017.69548. Epub 2017 Aug 30.


Extracellular S100A9 Protein in Bone Marrow Supports Multiple Myeloma Survival by Stimulating Angiogenesis and Cytokine Secretion.

De Veirman K, De Beule N, Maes K, Menu E, De Bruyne E, De Raeve H, Fostier K, Moreaux J, Kassambara A, Hose D, Heusschen R, Eriksson H, Vanderkerken K, Van Valckenborgh E.

Cancer Immunol Res. 2017 Oct;5(10):839-846. doi: 10.1158/2326-6066.CIR-17-0192. Epub 2017 Sep 13.


Experimental African trypanosome infection suppresses the development of multiple myeloma in mice by inducing intrinsic apoptosis of malignant plasma cells.

De Beule N, Menu E, Bertrand MJM, Favreau M, De Bruyne E, Maes K, De Veirman K, Radwanska M, Samali A, Magez S, Vanderkerken K, De Trez C.

Oncotarget. 2017 May 24;8(32):52016-52025. doi: 10.18632/oncotarget.18152. eCollection 2017 Aug 8.


Per Diems in Polio Eradication: Perspectives From Community Health Workers and Officials.

Closser S, Rosenthal A, Justice J, Maes K, Sultan M, Banerji S, Amaha HB, Gopinath R, Omidian P, Nyirazinyoye L.

Am J Public Health. 2017 Sep;107(9):1470-1476. doi: 10.2105/AJPH.2017.303886. Epub 2017 Jul 20.


Leptin receptor antagonism of iNKT cell function: a novel strategy to combat multiple myeloma.

Favreau M, Menu E, Gaublomme D, Vanderkerken K, Faict S, Maes K, De Bruyne E, Govindarajan S, Drennan M, Van Calenbergh S, Leleu X, Zabeau L, Tavernier J, Venken K, Elewaut D.

Leukemia. 2017 Dec;31(12):2678-2685. doi: 10.1038/leu.2017.146. Epub 2017 May 11.


Both mucosal-associated invariant and natural killer T-cell deficiency in multiple myeloma can be countered by PD-1 inhibition.

Favreau M, Venken K, Faict S, Maes K, De Veirman K, De Bruyne E, Leleu X, Boon L, Elewaut D, Vanderkerken K, Menu E.

Haematologica. 2017 Jul;102(7):e266-e270. doi: 10.3324/haematol.2017.163758. Epub 2017 Apr 6. No abstract available.


Documentation of pharmaceutical care: development of an intervention oriented classification system.

Maes KA, Bruch S, Hersberger KE, Lampert ML.

Int J Clin Pharm. 2017 Apr;39(2):354-363. doi: 10.1007/s11096-017-0442-6. Epub 2017 Mar 2.


High levels of PFOS in eggs of three bird species in the neighbourhood of a fluoro-chemical plant.

Lopez-Antia A, Dauwe T, Meyer J, Maes K, Bervoets L, Eens M.

Ecotoxicol Environ Saf. 2017 May;139:165-171. doi: 10.1016/j.ecoenv.2017.01.040.


Zonisamide attenuates lactacystin-induced parkinsonism in mice without affecting system xc<sup/>.

Bentea E, Van Liefferinge J, Verbruggen L, Martens K, Kobayashi S, Deneyer L, Demuyser T, Albertini G, Maes K, Sato H, Smolders I, Lewerenz J, Massie A.

Exp Neurol. 2017 Apr;290:15-28. doi: 10.1016/j.expneurol.2016.12.009. Epub 2016 Dec 24.


Tumour-associated macrophage-mediated survival of myeloma cells through STAT3 activation.

De Beule N, De Veirman K, Maes K, De Bruyne E, Menu E, Breckpot K, De Raeve H, Van Rampelbergh R, Van Ginderachter JA, Schots R, Van Valckenborgh E, Vanderkerken K.

J Pathol. 2017 Mar;241(4):534-546. doi: 10.1002/path.4860. Epub 2017 Jan 30.


Cachexia in cancer: what is in the definition?

Vanhoutte G, van de Wiel M, Wouters K, Sels M, Bartolomeeussen L, De Keersmaecker S, Verschueren C, De Vroey V, De Wilde A, Smits E, Cheung KJ, De Clerck L, Aerts P, Baert D, Vandoninck C, Kindt S, Schelfhaut S, Vankerkhoven M, Troch A, Ceulemans L, Vandenbergh H, Leys S, Rondou T, Dewitte E, Maes K, Pauwels P, De Winter B, Van Gaal L, Ysebaert D, Peeters M.

BMJ Open Gastroenterol. 2016 Oct 18;3(1):e000097. eCollection 2016.


Extracellular vesicle cross-talk in the bone marrow microenvironment: implications in multiple myeloma.

Wang J, Faict S, Maes K, De Bruyne E, Van Valckenborgh E, Schots R, Vanderkerken K, Menu E.

Oncotarget. 2016 Jun 21;7(25):38927-38945. doi: 10.18632/oncotarget.7792. Review.


The Transfer of Object Learning after Training with Multiple Exemplars.

Baeck A, Maes K, Meel CV, Op de Beeck HP.

Front Psychol. 2016 Sep 21;7:1386. eCollection 2016.


Influence of weaning methods on the diaphragm after mechanical ventilation in a rat model.

Bruells CS, Breuer T, Maes K, Bergs I, Bleilevens C, Marx G, Weis J, Gayan-Ramirez G, Rossaint R.

BMC Pulm Med. 2016 Aug 24;16(1):127. doi: 10.1186/s12890-016-0285-2.


The insulin-like growth factor system in multiple myeloma: diagnostic and therapeutic potential.

Bieghs L, Johnsen HE, Maes K, Menu E, Van Valckenborgh E, Overgaard MT, Nyegaard M, Conover CA, Vanderkerken K, De Bruyne E.

Oncotarget. 2016 Jul 26;7(30):48732-48752. doi: 10.18632/oncotarget.8982. Review.


Induction of miR-146a by multiple myeloma cells in mesenchymal stromal cells stimulates their pro-tumoral activity.

De Veirman K, Wang J, Xu S, Leleu X, Himpe E, Maes K, De Bruyne E, Van Valckenborgh E, Vanderkerken K, Menu E, Van Riet I.

Cancer Lett. 2016 Jul 10;377(1):17-24. doi: 10.1016/j.canlet.2016.04.024. Epub 2016 Apr 19.


The effects of smoking on whisker movements: A quantitative measure of exploratory behaviour in rodents.

Grant RA, Cielen N, Maes K, Heulens N, Galli GL, Janssens W, Gayan-Ramirez G, Degens H.

Behav Processes. 2016 Jul;128:17-23. doi: 10.1016/j.beproc.2016.03.021. Epub 2016 Apr 1.


Vitamin D deficiency impairs skeletal muscle function in a smoking mouse model.

Cielen N, Heulens N, Maes K, Carmeliet G, Mathieu C, Janssens W, Gayan-Ramirez G.

J Endocrinol. 2016 May;229(2):97-108. doi: 10.1530/JOE-15-0491. Epub 2016 Feb 23.


The Global Context of Vaccine Refusal: Insights from a Systematic Comparative Ethnography of the Global Polio Eradication Initiative.

Closser S, Rosenthal A, Maes K, Justice J, Cox K, Omidian PA, Mohammed IZ, Dukku AM, Koon AD, Nyirazinyoye L.

Med Anthropol Q. 2016 Sep;30(3):321-41. doi: 10.1111/maq.12254. Epub 2016 Jan 27.


Inhibiting the anaphase promoting complex/cyclosome induces a metaphase arrest and cell death in multiple myeloma cells.

Lub S, Maes A, Maes K, De Veirman K, De Bruyne E, Menu E, Fostier K, Kassambara A, Moreaux J, Hose D, Leleu X, King RW, Vanderkerken K, Van Valckenborgh E.

Oncotarget. 2016 Jan 26;7(4):4062-76. doi: 10.18632/oncotarget.6768.


Novel strategies to target the ubiquitin proteasome system in multiple myeloma.

Lub S, Maes K, Menu E, De Bruyne E, Vanderkerken K, Van Valckenborgh E.

Oncotarget. 2016 Feb 9;7(6):6521-37. doi: 10.18632/oncotarget.6658. Review.


Miniaturized ultra-high performance liquid chromatography coupled to electrochemical detection: Investigation of system performance for neurochemical analysis.

Van Schoors J, Maes K, Van Wanseele Y, Broeckhoven K, Van Eeckhaut A.

J Chromatogr A. 2016 Jan 4;1427:69-78. doi: 10.1016/j.chroma.2015.11.076. Epub 2015 Dec 2.


The bone marrow microenvironment enhances multiple myeloma progression by exosome-mediated activation of myeloid-derived suppressor cells.

Wang J, De Veirman K, De Beule N, Maes K, De Bruyne E, Van Valckenborgh E, Vanderkerken K, Menu E.

Oncotarget. 2015 Dec 22;6(41):43992-4004. doi: 10.18632/oncotarget.6083.


Interaction between Physical Activity and Smoking on Lung, Muscle, and Bone in Mice.

Cielen N, Maes K, Heulens N, Troosters T, Carmeliet G, Janssens W, Gayan-Ramirez GN.

Am J Respir Cell Mol Biol. 2016 May;54(5):674-82. doi: 10.1165/rcmb.2015-0181OC.


Vitamin D deficiency exacerbates COPD-like characteristics in the lungs of cigarette smoke-exposed mice.

Heulens N, Korf H, Cielen N, De Smidt E, Maes K, Gysemans C, Verbeken E, Gayan-Ramirez G, Mathieu C, Janssens W.

Respir Res. 2015 Sep 16;16:110. doi: 10.1186/s12931-015-0271-x.


Demonstrating the clinical pharmacist's activity: validation of an intervention oriented classification system.

Maes KA, Tremp RM; GSASA Working group on clinical pharmacy, Hersberger KE, Lampert ML.

Int J Clin Pharm. 2015 Dec;37(6):1162-71. doi: 10.1007/s11096-015-0179-z. Epub 2015 Aug 20.


Validation of the 6 Hz refractory seizure mouse model for intracerebroventricularly administered compounds.

Walrave L, Maes K, Coppens J, Bentea E, Van Eeckhaut A, Massie A, Van Liefferinge J, Smolders I.

Epilepsy Res. 2015 Sep;115:67-72. doi: 10.1016/j.eplepsyres.2015.06.003. Epub 2015 Jun 6.


Reassessment of the antioxidative mixture for the challenging electrochemical determination of dopamine, noradrenaline and serotonin in microdialysis samples.

Van Schoors J, Lens C, Maes K, Michotte Y, Smolders I, Van Eeckhaut A.

J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Aug 15;998-999:63-71. doi: 10.1016/j.jchromb.2015.06.010. Epub 2015 Jul 2.


The Global Context of Vaccine Refusal: Insights from a Systematic Comparative Ethnography of the Global Polio Eradication Initiative.

Closser S, Rosenthal A, Maes K, Justice J, Cox K, Omidian PA, Mohammed IZ, Dukku AM, Koon AD, Nyirazinyoye L.

Med Anthropol Q. 2015 Jun 18. doi: 10.1111/maq.12229. [Epub ahead of print]


Increased resistance to proteasome inhibitors in multiple myeloma mediated by cIAP2--implications for a combinatorial treatment.

Fristedt Duvefelt C, Lub S, Agarwal P, Arngården L, Hammarberg A, Maes K, Van Valckenborgh E, Vanderkerken K, Jernberg Wiklund H.

Oncotarget. 2015 Aug 21;6(24):20621-35.


Sevoflurane exposure prevents diaphragmatic oxidative stress during mechanical ventilation but reduces force and affects protein metabolism even during spontaneous breathing in a rat model.

Breuer T, Maes K, Rossaint R, Marx G, Scheers H, Bergs I, Bleilevens C, Gayan-Ramirez G, Bruells CS.

Anesth Analg. 2015 Jul;121(1):73-80. doi: 10.1213/ANE.0000000000000736.


An ultrasensitive nano UHPLC-ESI-MS/MS method for the quantification of three neuromedin-like peptides in microdialysates.

Maes K, Béchade G, Van Schoors J, Van Wanseele Y, Van Liefferinge J, Michotte Y, Harden SN, Chambers EE, Claereboudt J, Smolders I, Van Eeckhaut A.

Bioanalysis. 2015;7(5):605-19. doi: 10.4155/bio.14.269.


In vivo treatment with epigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma.

Maes K, De Smedt E, Kassambara A, Hose D, Seckinger A, Van Valckenborgh E, Menu E, Klein B, Vanderkerken K, Moreaux J, De Bruyne E.

Oncotarget. 2015 Feb 20;6(5):3319-34.


Effects of controlled mechanical ventilation on sepsis-induced diaphragm dysfunction in rats.

Maes K, Stamiris A, Thomas D, Cielen N, Smuder A, Powers SK, Leite FS, Hermans G, Decramer M, Hussain SN, Gayan-Ramirez G.

Crit Care Med. 2014 Dec;42(12):e772-82. doi: 10.1097/CCM.0000000000000685.


Improved sensitivity of the nano ultra-high performance liquid chromatography-tandem mass spectrometric analysis of low-concentrated neuropeptides by reducing aspecific adsorption and optimizing the injection solvent.

Maes K, Van Liefferinge J, Viaene J, Van Schoors J, Van Wanseele Y, Béchade G, Chambers EE, Morren H, Michotte Y, Vander Heyden Y, Claereboudt J, Smolders I, Van Eeckhaut A.

J Chromatogr A. 2014 Sep 19;1360:217-28. doi: 10.1016/j.chroma.2014.07.086. Epub 2014 Aug 1.


Strategies to reduce aspecific adsorption of peptides and proteins in liquid chromatography-mass spectrometry based bioanalyses: an overview.

Maes K, Smolders I, Michotte Y, Van Eeckhaut A.

J Chromatogr A. 2014 Sep 5;1358:1-13. doi: 10.1016/j.chroma.2014.06.072. Epub 2014 Jun 30. Review.


The IGF-1 receptor inhibitor picropodophyllin potentiates the anti-myeloma activity of a BH3-mimetic.

Bieghs L, Lub S, Fostier K, Maes K, Van Valckenborgh E, Menu E, Johnsen HE, Overgaard MT, Larsson O, Axelson M, Nyegaard M, Schots R, Jernberg-Wiklund H, Vanderkerken K, De Bruyne E.

Oncotarget. 2014 Nov 30;5(22):11193-208.


The role of DNA damage and repair in decitabine-mediated apoptosis in multiple myeloma.

Maes K, De Smedt E, Lemaire M, De Raeve H, Menu E, Van Valckenborgh E, McClue S, Vanderkerken K, De Bruyne E.

Oncotarget. 2014 May 30;5(10):3115-29.


Musculoskeletal disorders in chronic obstructive pulmonary disease.

Cielen N, Maes K, Gayan-Ramirez G.

Biomed Res Int. 2014;2014:965764. doi: 10.1155/2014/965764. Epub 2014 Mar 25. Review.


The impact of polio eradication on routine immunization and primary health care: a mixed-methods study.

Closser S, Cox K, Parris TM, Landis RM, Justice J, Gopinath R, Maes K, Banteyerga Amaha H, Mohammed IZ, Dukku AM, Omidian PA, Varley E, Tedoff P, Koon AD, Nyirazinyoye L, Luck MA, Pont WF, Neergheen V, Rosenthal A, Nsubuga P, Thacker N, Jooma R, Nuttall E.

J Infect Dis. 2014 Nov 1;210 Suppl 1:S504-13. doi: 10.1093/infdis/jit232. Epub 2014 Apr 1.


Listening to community health workers: how ethnographic research can inform positive relationships among community health workers, health institutions, and communities.

Maes K, Closser S, Kalofonos I.

Am J Public Health. 2014 May;104(5):e5-9. doi: 10.2105/AJPH.2014.301907. Epub 2014 Mar 13.


Sedation using propofol induces similar diaphragm dysfunction and atrophy during spontaneous breathing and mechanical ventilation in rats.

Bruells CS, Maes K, Rossaint R, Thomas D, Cielen N, Bergs I, Bleilevens C, Weis J, Gayan-Ramirez G.

Anesthesiology. 2014 Mar;120(3):665-72. doi: 10.1097/ALN.0000000000000125.


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