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Items: 1 to 50 of 129

1.

Antibodies that lIgAte our intestinal microbes.

Macpherson AJ, Yilmaz B.

Sci Immunol. 2018 May 4;3(23). pii: eaat4037. doi: 10.1126/sciimmunol.aat4037. Review.

PMID:
29728426
2.

Defective immuno- and thymoproteasome assembly causes severe immunodeficiency.

Treise I, Huber EM, Klein-Rodewald T, Heinemeyer W, Grassmann SA, Basler M, Adler T, Rathkolb B, Helming L, Andres C, Klaften M, Landbrecht C, Wieland T, Strom TM, McCoy KD, Macpherson AJ, Wolf E, Groettrup M, Ollert M, Neff F, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Groll M, Busch DH.

Sci Rep. 2018 Apr 13;8(1):5975. doi: 10.1038/s41598-018-24199-0.

3.

The immunological functions of the Appendix: An example of redundancy?

Girard-Madoux MJH, Gomez de Agüero M, Ganal-Vonarburg SC, Mooser C, Belz GT, Macpherson AJ, Vivier E.

Semin Immunol. 2018 Apr;36:31-44. doi: 10.1016/j.smim.2018.02.005. Epub 2018 Mar 2. Review.

PMID:
29503124
4.

IgA Function in Relation to the Intestinal Microbiota.

Macpherson AJ, Yilmaz B, Limenitakis JP, Ganal-Vonarburg SC.

Annu Rev Immunol. 2018 Apr 26;36:359-381. doi: 10.1146/annurev-immunol-042617-053238. Epub 2018 Jan 26.

PMID:
29400985
5.

A Gut Microbial Mimic that Hijacks Diabetogenic Autoreactivity to Suppress Colitis.

Hebbandi Nanjundappa R, Ronchi F, Wang J, Clemente-Casares X, Yamanouchi J, Sokke Umeshappa C, Yang Y, Blanco J, Bassolas-Molina H, Salas A, Khan H, Slattery RM, Wyss M, Mooser C, Macpherson AJ, Sycuro LK, Serra P, McKay DM, McCoy KD, Santamaria P.

Cell. 2017 Oct 19;171(3):655-667.e17. doi: 10.1016/j.cell.2017.09.022.

PMID:
29053971
6.

High-Quality Whole-Genome Sequences of the Oligo-Mouse-Microbiota Bacterial Community.

Garzetti D, Brugiroux S, Bunk B, Pukall R, McCoy KD, Macpherson AJ, Stecher B.

Genome Announc. 2017 Oct 19;5(42). pii: e00758-17. doi: 10.1128/genomeA.00758-17.

7.

The ESRP1-GPR137 axis contributes to intestinal pathogenesis.

Mager LF, Koelzer VH, Stuber R, Thoo L, Keller I, Koeck I, Langenegger M, Simillion C, Pfister SP, Faderl M, Genitsch V, Tcymbarevich I, Juillerat P, Li X, Xia Y, Karamitopoulou E, Lyck R, Zlobec I, Hapfelmeier S, Bruggmann R, McCoy KD, Macpherson AJ, Müller C, Beutler B, Krebs P.

Elife. 2017 Oct 4;6. pii: e28366. doi: 10.7554/eLife.28366.

8.

The Stimulation of Macrophages with TLR Ligands Supports Increased IL-19 Expression in Inflammatory Bowel Disease Patients and in Colitis Models.

Steinert A, Linas I, Kaya B, Ibrahim M, Schlitzer A, Hruz P, Radulovic K, Terracciano L, Macpherson AJ, Niess JH.

J Immunol. 2017 Oct 1;199(7):2570-2584. doi: 10.4049/jimmunol.1700350. Epub 2017 Sep 1.

PMID:
28864472
9.

Marginal abatement cost curve for nitrogen oxides incorporating controls, renewable electricity, energy efficiency, and fuel switching.

Loughlin DH, Macpherson AJ, Kaufman KR, Keaveny BN.

J Air Waste Manag Assoc. 2017 Oct;67(10):1115-1125. doi: 10.1080/10962247.2017.1342715.

PMID:
28613998
10.

How nutrition and the maternal microbiota shape the neonatal immune system.

Macpherson AJ, de Agüero MG, Ganal-Vonarburg SC.

Nat Rev Immunol. 2017 Aug;17(8):508-517. doi: 10.1038/nri.2017.58. Epub 2017 Jun 12. Review.

PMID:
28604736
11.
12.

Polyphenic trait promotes liver cancer in a model of epigenetic instability in mice.

Cassano M, Offner S, Planet E, Piersigilli A, Jang SM, Henry H, Geuking MB, Mooser C, McCoy KD, Macpherson AJ, Trono D.

Hepatology. 2017 Jul;66(1):235-251. doi: 10.1002/hep.29182. Epub 2017 May 18.

13.

Genome-guided design of a defined mouse microbiota that confers colonization resistance against Salmonella enterica serovar Typhimurium.

Brugiroux S, Beutler M, Pfann C, Garzetti D, Ruscheweyh HJ, Ring D, Diehl M, Herp S, Lötscher Y, Hussain S, Bunk B, Pukall R, Huson DH, Münch PC, McHardy AC, McCoy KD, Macpherson AJ, Loy A, Clavel T, Berry D, Stecher B.

Nat Microbiol. 2016 Nov 21;2:16215. doi: 10.1038/nmicrobiol.2016.215.

PMID:
27869789
14.

The Liver at the Nexus of Host-Microbial Interactions.

Macpherson AJ, Heikenwalder M, Ganal-Vonarburg SC.

Cell Host Microbe. 2016 Nov 9;20(5):561-571. doi: 10.1016/j.chom.2016.10.016. Review.

15.

Complete Genome Sequences of 12 Species of Stable Defined Moderately Diverse Mouse Microbiota 2.

Uchimura Y, Wyss M, Brugiroux S, Limenitakis JP, Stecher B, McCoy KD, Macpherson AJ.

Genome Announc. 2016 Sep 15;4(5). pii: e00951-16. doi: 10.1128/genomeA.00951-16.

16.

Analysis of bacterial-surface-specific antibodies in body fluids using bacterial flow cytometry.

Moor K, Fadlallah J, Toska A, Sterlin D, Balmer ML, Macpherson AJ, Gorochov G, Larsen M, Slack E.

Nat Protoc. 2016 Aug;11(8):1531-53. doi: 10.1038/nprot.2016.091. Epub 2016 Jul 28.

PMID:
27466712
17.

Our Mothers' Antibodies as Guardians of our Commensals.

Ganal-Vonarburg SC, Macpherson AJ.

Trends Mol Med. 2016 Sep;22(9):739-741. doi: 10.1016/j.molmed.2016.06.010. Epub 2016 Jul 19.

PMID:
27396513
18.

Memory CD8(+) T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function.

Balmer ML, Ma EH, Bantug GR, Grählert J, Pfister S, Glatter T, Jauch A, Dimeloe S, Slack E, Dehio P, Krzyzaniak MA, King CG, Burgener AV, Fischer M, Develioglu L, Belle R, Recher M, Bonilla WV, Macpherson AJ, Hapfelmeier S, Jones RG, Hess C.

Immunity. 2016 Jun 21;44(6):1312-24. doi: 10.1016/j.immuni.2016.03.016. Epub 2016 May 17.

19.

The maternal microbiota drives early postnatal innate immune development.

Gomez de Agüero M, Ganal-Vonarburg SC, Fuhrer T, Rupp S, Uchimura Y, Li H, Steinert A, Heikenwalder M, Hapfelmeier S, Sauer U, McCoy KD, Macpherson AJ.

Science. 2016 Mar 18;351(6279):1296-302. doi: 10.1126/science.aad2571.

20.

The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation.

Zaiss MM, Rapin A, Lebon L, Dubey LK, Mosconi I, Sarter K, Piersigilli A, Menin L, Walker AW, Rougemont J, Paerewijck O, Geldhof P, McCoy KD, Macpherson AJ, Croese J, Giacomin PR, Loukas A, Junt T, Marsland BJ, Harris NL.

Immunity. 2015 Nov 17;43(5):998-1010. doi: 10.1016/j.immuni.2015.09.012. Epub 2015 Oct 27.

21.

The outer mucus layer hosts a distinct intestinal microbial niche.

Li H, Limenitakis JP, Fuhrer T, Geuking MB, Lawson MA, Wyss M, Brugiroux S, Keller I, Macpherson JA, Rupp S, Stolp B, Stein JV, Stecher B, Sauer U, McCoy KD, Macpherson AJ.

Nat Commun. 2015 Sep 22;6:8292. doi: 10.1038/ncomms9292.

22.

Independence Day for IgA.

Macpherson AJ, McCoy KD.

Immunity. 2015 Sep 15;43(3):416-8. doi: 10.1016/j.immuni.2015.08.024.

23.

CD4 T cells are required for both development and maintenance of disease in a new mouse model of reversible colitis.

Brasseit J, Althaus-Steiner E, Faderl M, Dickgreber N, Saurer L, Genitsch V, Dolowschiak T, Li H, Finke D, Hardt WD, McCoy KD, Macpherson AJ, Corazza N, Noti M, Mueller C.

Mucosal Immunol. 2016 May;9(3):689-701. doi: 10.1038/mi.2015.93. Epub 2015 Sep 16.

PMID:
26376366
24.

The bilateral responsiveness between intestinal microbes and IgA.

Macpherson AJ, Köller Y, McCoy KD.

Trends Immunol. 2015 Aug;36(8):460-70. doi: 10.1016/j.it.2015.06.006. Epub 2015 Jul 11. Review.

PMID:
26169256
25.

IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms.

Mager LF, Riether C, Schürch CM, Banz Y, Wasmer MH, Stuber R, Theocharides AP, Li X, Xia Y, Saito H, Nakae S, Baerlocher GM, Manz MG, McCoy KD, Macpherson AJ, Ochsenbein AF, Beutler B, Krebs P.

J Clin Invest. 2015 Jul 1;125(7):2579-91. doi: 10.1172/JCI77347. Epub 2015 May 26.

26.

Attenuated portal hypertension in germ-free mice: Function of bacterial flora on the development of mesenteric lymphatic and blood vessels.

Moghadamrad S, McCoy KD, Geuking MB, Sägesser H, Kirundi J, Macpherson AJ, De Gottardi A.

Hepatology. 2015 May;61(5):1685-95. doi: 10.1002/hep.27698. Epub 2015 Feb 24.

PMID:
25643846
27.

Penetrability of the inner mucus layer: who is out there?

Li H, Limenitakis JP, Ganal SC, Macpherson AJ.

EMBO Rep. 2015 Feb;16(2):127-9. doi: 10.15252/embr.201439943. Epub 2015 Jan 8. No abstract available.

28.

Factors associated with durable response to infliximab in Crohn's disease 5 years and beyond: a multicenter international cohort.

Juillerat P, Sokol H, Froehlich F, Yajnik V, Beaugerie L, Lucci M, Burnand B, Macpherson AJ, Cosnes J, Korzenik JR.

Inflamm Bowel Dis. 2015 Jan;21(1):60-70. doi: 10.1097/MIB.0000000000000225.

PMID:
25517594
29.

Standardised animal models of host microbial mutualism.

Macpherson AJ, McCoy KD.

Mucosal Immunol. 2015 May;8(3):476-86. doi: 10.1038/mi.2014.113. Epub 2014 Dec 10. Review.

30.

Microbiota-derived compounds drive steady-state granulopoiesis via MyD88/TICAM signaling.

Balmer ML, Schürch CM, Saito Y, Geuking MB, Li H, Cuenca M, Kovtonyuk LV, McCoy KD, Hapfelmeier S, Ochsenbein AF, Manz MG, Slack E, Macpherson AJ.

J Immunol. 2014 Nov 15;193(10):5273-83. doi: 10.4049/jimmunol.1400762. Epub 2014 Oct 10.

31.

An ambulance for retinol.

Ganal SC, MacPherson AJ.

Elife. 2014 Sep 2;3:e04246. doi: 10.7554/eLife.04246.

32.

B cells as a critical node in the microbiota-host immune system network.

Slack E, Balmer ML, Macpherson AJ.

Immunol Rev. 2014 Jul;260(1):50-66. doi: 10.1111/imr.12179. Review.

PMID:
24942681
33.

The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota.

Balmer ML, Slack E, de Gottardi A, Lawson MA, Hapfelmeier S, Miele L, Grieco A, Van Vlierberghe H, Fahrner R, Patuto N, Bernsmeier C, Ronchi F, Wyss M, Stroka D, Dickgreber N, Heim MH, McCoy KD, Macpherson AJ.

Sci Transl Med. 2014 May 21;6(237):237ra66. doi: 10.1126/scitranslmed.3008618.

34.

Segmented filamentous bacterium uses secondary and tertiary lymphoid tissues to induce gut IgA and specific T helper 17 cell responses.

Lécuyer E, Rakotobe S, Lengliné-Garnier H, Lebreton C, Picard M, Juste C, Fritzen R, Eberl G, McCoy KD, Macpherson AJ, Reynaud CA, Cerf-Bensussan N, Gaboriau-Routhiau V.

Immunity. 2014 Apr 17;40(4):608-20. doi: 10.1016/j.immuni.2014.03.009.

35.

Stratification and compartmentalisation of immunoglobulin responses to commensal intestinal microbes.

Macpherson AJ, McCoy KD.

Semin Immunol. 2013 Nov 30;25(5):358-63. doi: 10.1016/j.smim.2013.09.004. Epub 2013 Nov 12. Review.

PMID:
24238818
36.

Metabolites from intestinal microbes shape Treg.

Geuking MB, McCoy KD, Macpherson AJ.

Cell Res. 2013 Dec;23(12):1339-40. doi: 10.1038/cr.2013.125. Epub 2013 Sep 10.

37.

Controlling for exogenous environmental variables when using data envelopment analysis for regional environmental assessments.

Macpherson AJ, Principe PP, Shao Y.

J Environ Manage. 2013 Apr 15;119:220-9. doi: 10.1016/j.jenvman.2012.12.044. Epub 2013 Mar 22.

PMID:
23500024
38.

Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity.

Markle JG, Frank DN, Mortin-Toth S, Robertson CE, Feazel LM, Rolle-Kampczyk U, von Bergen M, McCoy KD, Macpherson AJ, Danska JS.

Science. 2013 Mar 1;339(6123):1084-8. doi: 10.1126/science.1233521. Epub 2013 Jan 17.

39.

Assessing sediment yield for selected watersheds in the Laurentian Great Lakes Basin under future agricultural scenarios.

Shao Y, Lunetta RS, Macpherson AJ, Luo J, Chen G.

Environ Manage. 2013 Jan;51(1):59-69. doi: 10.1007/s00267-012-9903-9. Epub 2012 Jul 13.

PMID:
22791140
40.

Interactions between the microbiota and the immune system.

Hooper LV, Littman DR, Macpherson AJ.

Science. 2012 Jun 8;336(6086):1268-73. doi: 10.1126/science.1223490. Epub 2012 Jun 6. Review.

41.

Generation and analysis of a mouse intestinal metatranscriptome through Illumina based RNA-sequencing.

Xiong X, Frank DN, Robertson CE, Hung SS, Markle J, Canty AJ, McCoy KD, Macpherson AJ, Poussier P, Danska JS, Parkinson J.

PLoS One. 2012;7(4):e36009. doi: 10.1371/journal.pone.0036009. Epub 2012 Apr 27.

42.

Homeland security: IgA immunity at the frontiers of the body.

Macpherson AJ, Geuking MB, McCoy KD.

Trends Immunol. 2012 Apr;33(4):160-7. doi: 10.1016/j.it.2012.02.002. Epub 2012 Mar 10. Review.

PMID:
22410243
43.

Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine.

Lindner C, Wahl B, Föhse L, Suerbaum S, Macpherson AJ, Prinz I, Pabst O.

J Exp Med. 2012 Feb 13;209(2):365-77. doi: 10.1084/jem.20111980. Epub 2012 Jan 16.

44.

Innate and adaptive immunity in host-microbiota mutualism.

Macpherson AJ, Geuking MB, McCoy KD.

Front Biosci (Schol Ed). 2012 Jan 1;4:685-98. Review.

PMID:
22202085
45.

The habitat, double life, citizenship, and forgetfulness of IgA.

Macpherson AJ, Geuking MB, Slack E, Hapfelmeier S, McCoy KD.

Immunol Rev. 2012 Jan;245(1):132-46. doi: 10.1111/j.1600-065X.2011.01072.x. Review.

PMID:
22168417
46.

Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut.

Fritz JH, Rojas OL, Simard N, McCarthy DD, Hapfelmeier S, Rubino S, Robertson SJ, Larijani M, Gosselin J, Ivanov II, Martin A, Casellas R, Philpott DJ, Girardin SE, McCoy KD, Macpherson AJ, Paige CJ, Gommerman JL.

Nature. 2011 Dec 11;481(7380):199-203. doi: 10.1038/nature10698.

47.

The continuum of intestinal CD4+ T cell adaptations in host-microbial mutualism.

Geuking MB, McCoy KD, Macpherson AJ.

Gut Microbes. 2011 Nov-Dec;2(6):353-7. doi: 10.4161/gmic.18604. Epub 2011 Nov 1.

PMID:
22157235
48.

The function of secretory IgA in the context of the intestinal continuum of adaptive immune responses in host-microbial mutualism.

Geuking MB, McCoy KD, Macpherson AJ.

Semin Immunol. 2012 Feb;24(1):36-42. doi: 10.1016/j.smim.2011.11.005. Epub 2011 Dec 3. Review.

PMID:
22138187
49.

Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut.

Shulzhenko N, Morgun A, Hsiao W, Battle M, Yao M, Gavrilova O, Orandle M, Mayer L, Macpherson AJ, McCoy KD, Fraser-Liggett C, Matzinger P.

Nat Med. 2011 Nov 20;17(12):1585-93. doi: 10.1038/nm.2505.

50.

Immunoglobulin A: a bridge between innate and adaptive immunity.

Macpherson AJ, Geuking MB, McCoy KD.

Curr Opin Gastroenterol. 2011 Oct;27(6):529-33. doi: 10.1097/MOG.0b013e32834bb805. Review.

PMID:
21912248

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