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Items: 1 to 50 of 61

1.

Biological and mechanical interplay at the Macro- and Microscales Modulates the Cell-Niche Fate.

Sarig U, Sarig H, Gora A, Krishnamoorthi MK, Au-Yeung GCT, de-Berardinis E, Chaw SY, Mhaisalkar P, Bogireddi H, Ramakrishna S, Boey FYC, Venkatraman SS, Machluf M.

Sci Rep. 2018 Mar 2;8(1):3937. doi: 10.1038/s41598-018-21860-6.

2.

Therapy-Educated Mesenchymal Stem Cells Enrich for Tumor-Initiating Cells.

Timaner M, Letko-Khait N, Kotsofruk R, Benguigui M, Beyar-Katz O, Rachman-Tzemah C, Raviv Z, Bronshtein T, Machluf M, Shaked Y.

Cancer Res. 2018 Mar 1;78(5):1253-1265. doi: 10.1158/0008-5472.CAN-17-1547. Epub 2018 Jan 4.

3.

Delivery of the gene encoding the tumor suppressor Sef into prostate tumors by therapeutic-ultrasound inhibits both tumor angiogenesis and growth.

Mishel S, Shneyer B, Korsensky L, Goldshmidt-Tran O, Haber T, Machluf M, Ron D.

Sci Rep. 2017 Nov 8;7(1):15060. doi: 10.1038/s41598-017-12408-1.

4.

Restoring the biophysical properties of decellularized patches through recellularization.

Chi Ting Au-Yeung G, Sarig U, Sarig H, Bogireddi H, Bronshtein T, Baruch L, Spizzichino A, Bortman J, Freddy BYC, Machluf M, Venkatraman SS.

Biomater Sci. 2017 May 30;5(6):1183-1194. doi: 10.1039/c7bm00208d.

PMID:
28513656
5.

Ultrasound-Mediated Mesenchymal Stem Cells Transfection as a Targeted Cancer Therapy Platform.

Haber T, Baruch L, Machluf M.

Sci Rep. 2017 Feb 7;7:42046. doi: 10.1038/srep42046.

6.

Biohybrid cardiac ECM-based hydrogels improve long term cardiac function post myocardial infarction.

Efraim Y, Sarig H, Cohen Anavy N, Sarig U, de Berardinis E, Chaw SY, Krishnamoorthi M, Kalifa J, Bogireddi H, Duc TV, Kofidis T, Baruch L, Boey FYC, Venkatraman SS, Machluf M.

Acta Biomater. 2017 Mar 1;50:220-233. doi: 10.1016/j.actbio.2016.12.015. Epub 2016 Dec 9.

PMID:
27956366
7.

Dynamic Autologous Reendothelialization of Small-Caliber Arterial Extracellular Matrix: A Preclinical Large Animal Study.

Dahan N, Sarig U, Bronshtein T, Baruch L, Karram T, Hoffman A, Machluf M.

Tissue Eng Part A. 2017 Jan;23(1-2):69-79. doi: 10.1089/ten.TEA.2016.0126. Epub 2016 Dec 20.

8.

Natural myocardial ECM patch drives cardiac progenitor based restoration even after scarring.

Sarig U, Sarig H, de-Berardinis E, Chaw SY, Nguyen EB, Ramanujam VS, Thang VD, Al-Haddawi M, Liao S, Seliktar D, Kofidis T, Boey FY, Venkatraman SS, Machluf M.

Acta Biomater. 2016 Oct 15;44:209-20. doi: 10.1016/j.actbio.2016.08.031. Epub 2016 Aug 18.

9.

Innovative encapsulation platform based on pancreatic extracellular matrix achieve substantial insulin delivery.

Chaimov D, Baruch L, Krishtul S, Meivar-Levy I, Ferber S, Machluf M.

J Control Release. 2017 Jul 10;257:91-101. doi: 10.1016/j.jconrel.2016.07.045. Epub 2016 Jul 28.

PMID:
27476611
10.

Nanoghosts as a Novel Natural Nonviral Gene Delivery Platform Safely Targeting Multiple Cancers.

Kaneti L, Bronshtein T, Malkah Dayan N, Kovregina I, Letko Khait N, Lupu-Haber Y, Fliman M, Schoen BW, Kaneti G, Machluf M.

Nano Lett. 2016 Mar 9;16(3):1574-82. doi: 10.1021/acs.nanolett.5b04237. Epub 2016 Feb 24.

PMID:
26901695
11.

PLGA-Listeriolysin O microspheres: Opening the gate for cytosolic delivery of cancer antigens.

Gilert A, Baruch L, Bronshtein T, Machluf M.

Biomed Microdevices. 2016 Apr;18(2):23. doi: 10.1007/s10544-016-0050-6.

PMID:
26888439
12.

The effect of AZD2171- or sTRAIL/Apo2L-loaded polylactic-co-glycolic acid microspheres on a subcutaneous glioblastoma model.

Shivinsky A, Bronshtein T, Haber T, Machluf M.

Biomed Microdevices. 2015 Aug;17(4):69. doi: 10.1007/s10544-015-9969-2.

PMID:
26044202
13.

Blocking IL1β Pathway Following Paclitaxel Chemotherapy Slightly Inhibits Primary Tumor Growth but Promotes Spontaneous Metastasis.

Voloshin T, Alishekevitz D, Kaneti L, Miller V, Isakov E, Kaplanov I, Voronov E, Fremder E, Benhar M, Machluf M, Apte RN, Shaked Y.

Mol Cancer Ther. 2015 Jun;14(6):1385-94. doi: 10.1158/1535-7163.MCT-14-0969. Epub 2015 Apr 17.

14.

Printing cell-laden gelatin constructs by free-form fabrication and enzymatic protein crosslinking.

Irvine SA, Agrawal A, Lee BH, Chua HY, Low KY, Lau BC, Machluf M, Venkatraman S.

Biomed Microdevices. 2015 Feb;17(1):16. doi: 10.1007/s10544-014-9915-8.

15.

Pushing the envelope in tissue engineering: ex vivo production of thick vascularized cardiac extracellular matrix constructs.

Sarig U, Nguyen EB, Wang Y, Ting S, Bronshtein T, Sarig H, Dahan N, Gvirtz M, Reuveny S, Oh SK, Scheper T, Boey YC, Venkatraman SS, Machluf M.

Tissue Eng Part A. 2015 May;21(9-10):1507-19. doi: 10.1089/ten.TEA.2014.0477. Epub 2015 Mar 19.

16.

Characterization of a bioactive fiber scaffold with entrapped HUVECs in coaxial electrospun core-shell fiber.

Ang HY, Irvine SA, Avrahami R, Sarig U, Bronshtein T, Zussman E, Boey FY, Machluf M, Venkatraman SS.

Biomatter. 2014;4:e28238. doi: 10.4161/biom.28238. Epub 2014 Feb 19.

17.

Insight concerning the mechanism of therapeutic ultrasound facilitating gene delivery: increasing cell membrane permeability or interfering with intracellular pathways?

Duvshani-Eshet M, Haber T, Machluf M.

Hum Gene Ther. 2014 Feb;25(2):156-64. doi: 10.1089/hum.2013.140. Epub 2014 Jan 7.

18.

Functionalized PLGA-doped zirconium oxide ceramics for bone tissue regeneration.

Lupu-Haber Y, Pinkas O, Boehm S, Scheper T, Kasper C, Machluf M.

Biomed Microdevices. 2013 Dec;15(6):1055-66. doi: 10.1007/s10544-013-9797-1.

PMID:
23893013
19.

Reconstructed stem cell nanoghosts: a natural tumor targeting platform.

Toledano Furman NE, Lupu-Haber Y, Bronshtein T, Kaneti L, Letko N, Weinstein E, Baruch L, Machluf M.

Nano Lett. 2013 Jul 10;13(7):3248-55. doi: 10.1021/nl401376w. Epub 2013 Jun 24.

PMID:
23786263
20.

Collagen-cellulose composite thin films that mimic soft-tissue and allow stem-cell orientation.

Steele TW, Huang CL, Nguyen E, Sarig U, Kumar S, Widjaja E, Loo JS, Machluf M, Boey F, Vukadinovic Z, Hilfiker A, Venkatraman SS.

J Mater Sci Mater Med. 2013 Aug;24(8):2013-27. doi: 10.1007/s10856-013-4940-3. Epub 2013 May 14.

PMID:
23670603
21.

A mathematical model for analyzing the elasticity, viscosity, and failure of soft tissue: comparison of native and decellularized porcine cardiac extracellular matrix for tissue engineering.

Bronshtein T, Au-Yeung GC, Sarig U, Nguyen EB, Mhaisalkar PS, Boey FY, Venkatraman SS, Machluf M.

Tissue Eng Part C Methods. 2013 Aug;19(8):620-30. doi: 10.1089/ten.TEC.2012.0387. Epub 2013 Apr 5.

22.

A mathematical model predicting the coculture dynamics of endothelial and mesenchymal stem cells for tissue regeneration.

Wang Y, Bronshtein T, Sarig U, Nguyen EB, Boey FY, Venkatraman SS, Machluf M.

Tissue Eng Part A. 2013 May;19(9-10):1155-64. doi: 10.1089/ten.TEA.2012.0507. Epub 2013 Jan 16.

23.

Thick acellular heart extracellular matrix with inherent vasculature: a potential platform for myocardial tissue regeneration.

Sarig U, Au-Yeung GC, Wang Y, Bronshtein T, Dahan N, Boey FY, Venkatraman SS, Machluf M.

Tissue Eng Part A. 2012 Oct;18(19-20):2125-37. doi: 10.1089/ten.TEA.2011.0586. Epub 2012 Jul 19.

24.

Osteogenic Differentiation of adipose mesenchymal stem cells with BMP-2 embedded microspheres in a rotating bed bioreactor.

Boehm S, Lupu Y, Machluf M, Kasper C.

BMC Proc. 2011 Nov 22;5 Suppl 8:P74. doi: 10.1186/1753-6561-5-S8-P74. eCollection 2011. No abstract available.

25.

Alginate encapsulated cells secreting Fas-ligand reduce lymphoma carcinogenicity.

Goren A, Gilert A, Meyron-Holtz E, Melamed D, Machluf M.

Cancer Sci. 2012 Jan;103(1):116-24. doi: 10.1111/j.1349-7006.2011.02124.x. Epub 2011 Nov 27.

26.

Porcine small diameter arterial extracellular matrix supports endothelium formation and media remodeling forming a promising vascular engineered biograft.

Dahan N, Zarbiv G, Sarig U, Karram T, Hoffman A, Machluf M.

Tissue Eng Part A. 2012 Feb;18(3-4):411-22. doi: 10.1089/ten.TEA.2011.0173. Epub 2011 Dec 2.

PMID:
21919798
27.

Engineering cell platforms for myocardial regeneration.

Sarig U, Machluf M.

Expert Opin Biol Ther. 2011 Aug;11(8):1055-77. doi: 10.1517/14712598.2011.578574. Epub 2011 May 5. Review.

PMID:
21542780
28.

Cell derived liposomes expressing CCR5 as a new targeted drug-delivery system for HIV infected cells.

Bronshtein T, Toledano N, Danino D, Pollack S, Machluf M.

J Control Release. 2011 Apr 30;151(2):139-48. doi: 10.1016/j.jconrel.2011.02.023. Epub 2011 Feb 26.

PMID:
21362450
29.

Nano to micro delivery systems: targeting angiogenesis in brain tumors.

Gilert A, Machluf M.

J Angiogenes Res. 2010 Oct 8;2(1):20. doi: 10.1186/2040-2384-2-20.

30.

Novel local drug delivery system using thermoreversible gel in combination with polymeric microspheres or liposomes.

Arai T, Benny O, Joki T, Menon LG, Machluf M, Abe T, Carroll RS, Black PM.

Anticancer Res. 2010 Apr;30(4):1057-64.

PMID:
20530409
31.

Acellular cardiac extracellular matrix as a scaffold for tissue engineering: in vitro cell support, remodeling, and biocompatibility.

Eitan Y, Sarig U, Dahan N, Machluf M.

Tissue Eng Part C Methods. 2010 Aug;16(4):671-83. doi: 10.1089/ten.TEC.2009.0111.

PMID:
19780649
32.

Encapsulated human mesenchymal stem cells: a unique hypoimmunogenic platform for long-term cellular therapy.

Goren A, Dahan N, Goren E, Baruch L, Machluf M.

FASEB J. 2010 Jan;24(1):22-31. doi: 10.1096/fj.09-131888. Epub 2009 Sep 2.

PMID:
19726759
33.

Alginate-PLL cell encapsulation system Co-entrapping PLGA-microspheres for the continuous release of anti-inflammatory drugs.

Baruch L, Benny O, Gilert A, Ukobnik M, Ben Itzhak O, Machluf M.

Biomed Microdevices. 2009 Oct;11(5):1103-13. doi: 10.1007/s10544-009-9327-3. Epub 2009 Jun 11.

PMID:
19517239
34.

Development of ALS-like disease in SOD-1 mice deficient of B lymphocytes.

Naor S, Keren Z, Bronshtein T, Goren E, Machluf M, Melamed D.

J Neurol. 2009 Aug;256(8):1228-35. doi: 10.1007/s00415-009-5097-3. Epub 2009 Mar 12.

PMID:
19280101
35.

Local delivery of poly lactic-co-glycolic acid microspheres containing imatinib mesylate inhibits intracranial xenograft glioma growth.

Benny O, Menon LG, Ariel G, Goren E, Kim SK, Stewman C, Black PM, Carroll RS, Machluf M.

Clin Cancer Res. 2009 Feb 15;15(4):1222-31. doi: 10.1158/1078-0432.CCR-08-1316. Epub 2009 Feb 3.

36.

Effect of peptides bearing nuclear localization signals on therapeutic ultrasound mediated gene delivery.

Duvshani-Eshet M, Keren H, Oz S, Radzishevsky IS, Mor A, Machluf M.

J Gene Med. 2008 Oct;10(10):1150-9. doi: 10.1002/jgm.1235.

PMID:
18613288
37.

Indole-3-carbinol (I3C) exhibits inhibitory and preventive effects on prostate tumors in mice.

Souli E, Machluf M, Morgenstern A, Sabo E, Yannai S.

Food Chem Toxicol. 2008 Mar;46(3):863-70. Epub 2007 Oct 30.

PMID:
18063461
38.

In vivo fate and therapeutic efficacy of PF-4/CTF microspheres in an orthotopic human glioblastoma model.

Benny O, Kim SK, Gvili K, Radzishevsky IS, Mor A, Verduzco L, Menon LG, Black PM, Machluf M, Carroll RS.

FASEB J. 2008 Feb;22(2):488-99. Epub 2007 Sep 14.

PMID:
17873103
39.

Therapeutic ultrasound facilitates antiangiogenic gene delivery and inhibits prostate tumor growth.

Duvshani-Eshet M, Benny O, Morgenstern A, Machluf M.

Mol Cancer Ther. 2007 Aug;6(8):2371-82.

40.

Poly(D,L-lactide-co-glycolide acid) nanoparticles for DNA delivery: waiving preparation complexity and increasing efficiency.

Gvili K, Benny O, Danino D, Machluf M.

Biopolymers. 2007 Apr 5-15;85(5-6):379-91.

PMID:
17266128
41.
42.

The effects of albumin-coated microbubbles in DNA delivery mediated by therapeutic ultrasound.

Duvshani-Eshet M, Adam D, Machluf M.

J Control Release. 2006 May 15;112(2):156-66. Epub 2006 Feb 28.

PMID:
16632040
43.
44.

Therapeutic ultrasound optimization for gene delivery: a key factor achieving nuclear DNA localization.

Duvshani-Eshet M, Machluf M.

J Control Release. 2005 Nov 28;108(2-3):513-28. Epub 2005 Oct 20.

PMID:
16243409
45.

Therapeutic ultrasound-mediated DNA to cell and nucleus: bioeffects revealed by confocal and atomic force microscopy.

Duvshani-Eshet M, Baruch L, Kesselman E, Shimoni E, Machluf M.

Gene Ther. 2006 Jan;13(2):163-72.

PMID:
16177822
46.

PEX-producing human neural stem cells inhibit tumor growth in a mouse glioma model.

Kim SK, Cargioli TG, Machluf M, Yang W, Sun Y, Al-Hashem R, Kim SU, Black PM, Carroll RS.

Clin Cancer Res. 2005 Aug 15;11(16):5965-70.

47.

Continuous delivery of endogenous inhibitors from poly(lactic-co-glycolic acid) polymeric microspheres inhibits glioma tumor growth.

Benny O, Duvshani-Eshet M, Cargioli T, Bello L, Bikfalvi A, Carroll RS, Machluf M.

Clin Cancer Res. 2005 Jan 15;11(2 Pt 1):768-76.

48.

Cell-based delivery systems for antiangiogenic therapy.

Machluf M, Carroll RS.

Biotechnol Genet Eng Rev. 2003;20:183-95. Review. No abstract available.

PMID:
14997852
49.

Semaphorin-3F is an inhibitor of tumor angiogenesis.

Kessler O, Shraga-Heled N, Lange T, Gutmann-Raviv N, Sabo E, Baruch L, Machluf M, Neufeld G.

Cancer Res. 2004 Feb 1;64(3):1008-15.

50.

Endostatin inhibits the vascular endothelial growth factor-induced mobilization of endothelial progenitor cells.

Schuch G, Heymach JV, Nomi M, Machluf M, Force J, Atala A, Eder JP Jr, Folkman J, Soker S.

Cancer Res. 2003 Dec 1;63(23):8345-50.

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