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Dose intensification of TRAIL-inducing ONC201 inhibits metastasis and promotes intratumoral NK cell recruitment.

Wagner J, Kline CL, Zhou L, Campbell KS, MacFarlane AW, Olszanski AJ, Cai KQ, Hensley HH, Ross EA, Ralff MD, Zloza A, Chesson CB, Newman JH, Kaufman H, Bertino JR, Stein MN, El-Deiry W.

J Clin Invest. 2018 Mar 13. pii: 96711. doi: 10.1172/JCI96711. [Epub ahead of print]


Defining a framework for medical teachers' competencies to teach ethnic and cultural diversity: Results of a European Delphi study.

Hordijk R, Hendrickx K, Lanting K, MacFarlane A, Muntinga M, Suurmond J.

Med Teach. 2018 Feb 28:1-7. doi: 10.1080/0142159X.2018.1439160. [Epub ahead of print]


Using Participatory Learning & Action (PLA) research techniques for inter-stakeholder dialogue in primary healthcare: an analysis of stakeholders' experiences.

de Brún T, O'Reilly-de Brún M, Van Weel-Baumgarten E, Burns N, Dowrick C, Lionis C, O'Donnell C, Mair FS, Papadakaki M, Saridaki A, Spiegel W, Van Weel C, Van den Muijsenbergh M, MacFarlane A.

Res Involv Engagem. 2017 Dec 6;3:28. doi: 10.1186/s40900-017-0077-8. eCollection 2017.


Sex, drugs and self-control: why chemsex is fast becoming a public health concern.

Macfarlane A.

J Fam Plann Reprod Health Care. 2016 Oct;42(4):291-294. doi: 10.1136/jfprhc-2016-101576. No abstract available.


Application of 3D tumoroid systems to define immune and cytotoxic therapeutic responses based on tumoroid and tissue slice culture molecular signatures.

Finnberg NK, Gokare P, Lev A, Grivennikov SI, MacFarlane AW 4th, Campbell KS, Winters RM, Kaputa K, Farma JM, Abbas AE, Grasso L, Nicolaides NC, El-Deiry WS.

Oncotarget. 2017 Aug 5;8(40):66747-66757. doi: 10.18632/oncotarget.19965. eCollection 2017 Sep 15.


Image Gallery: Annular elastolytic giant cell granuloma responding to hydroxychloroquine therapy.

Arzpayma P, Macfarlane A.

Br J Dermatol. 2017 Sep;177(3):e74. doi: 10.1111/bjd.15792. No abstract available.


The anti-SLAMF7 antibody elotuzumab mediates NK cell activation through both CD16-dependent and -independent mechanisms.

Pazina T, James AM, MacFarlane AW 4th, Bezman NA, Henning KA, Bee C, Graziano RF, Robbins MD, Cohen AD, Campbell KS.

Oncoimmunology. 2017 Jun 16;6(9):e1339853. doi: 10.1080/2162402X.2017.1339853. eCollection 2017.


Material practices for meaningful engagement: An analysis of participatory learning and action research techniques for data generation and analysis in a health research partnership.

O'Reilly-de Brún M, de Brún T, O'Donnell CA, Papadakaki M, Saridaki A, Lionis C, Burns N, Dowrick C, Gravenhorst K, Spiegel W, Van Weel C, Van Weel-Baumgarten E, Van den Muijsenbergh M, MacFarlane A.

Health Expect. 2018 Feb;21(1):159-170. doi: 10.1111/hex.12598. Epub 2017 Aug 25.


Supporting the use of theory in cross-country health services research: a participatory qualitative approach using Normalisation Process Theory as an example.

O'Donnell CA, Mair FS, Dowrick C, Brún MO, Brún T, Burns N, Lionis C, Saridaki A, Papadakaki M, Muijsenbergh MVD, Weel-Baumgarten EV, Gravenhorst K, Cooper L, Princz C, Teunissen E, Mareeuw FVDD, Vlahadi M, Spiegel W, MacFarlane A.

BMJ Open. 2017 Aug 21;7(8):e014289. doi: 10.1136/bmjopen-2016-014289.


NK cell dysfunction in chronic lymphocytic leukemia is associated with loss of the mature cells expressing inhibitory killer cell Ig-like receptors.

MacFarlane AW 4th, Jillab M, Smith MR, Alpaugh RK, Cole ME, Litwin S, Millenson MM, Al-Saleem T, Cohen AD, Campbell KS.

Oncoimmunology. 2017 May 19;6(7):e1330235. doi: 10.1080/2162402X.2017.1330235. eCollection 2017.


Developing international open science collaborations: Funder reflections on the Open Science Prize.

Kittrie E, Atienza AA, Kiley R, Carr D, MacFarlane A, Pai V, Couch J, Bajkowski J, Bonner JF, Mietchen D, Bourne PE.

PLoS Biol. 2017 Aug 1;15(8):e2002617. doi: 10.1371/journal.pbio.2002617. eCollection 2017 Aug.


Correction: Assessing the facilitators and barriers of interdisciplinary team working in primary care using normalisation process theory: An integrative review.

O'Reilly P, Lee SH, O'Sullivan M, Cullen W, Kennedy C, MacFarlane A.

PLoS One. 2017 Jul 24;12(7):e0181893. doi: 10.1371/journal.pone.0181893. eCollection 2017.


Déjà vu for U.S. nuclear waste.

Macfarlane A, Ewing R.

Science. 2017 Jun 30;356(6345):1313. doi: 10.1126/science.aao1711. No abstract available.


Comparison of enhanced liver fibrosis test with procollagen-3 N-terminal peptide (P3NP) as a marker for liver fibrosis.

Arzpayma P, Callander J, Macfarlane A.

Br J Dermatol. 2017 Jun;176(6):1439-1440. doi: 10.1111/bjd.15590. No abstract available.


How do late terminations of pregnancy affect comparisons of stillbirth rates in Europe? Analyses of aggregated routine data from the Euro-Peristat Project.

Blondel B, Cuttini M, Hindori-Mohangoo AD, Gissler M, Loghi M, Prunet C, Heino A, Smith L, van der Pal-de Bruin K, Macfarlane A, Zeitlin J; Euro-Peristat Scientific Committee.

BJOG. 2018 Jan;125(2):226-234. doi: 10.1111/1471-0528.14767. Epub 2017 Jul 17.


Assessing the facilitators and barriers of interdisciplinary team working in primary care using normalisation process theory: An integrative review.

O'Reilly P, Lee SH, O'Sullivan M, Cullen W, Kennedy C, MacFarlane A.

PLoS One. 2017 May 18;12(5):e0177026. doi: 10.1371/journal.pone.0177026. eCollection 2017. Review. Erratum in: PLoS One. 2017 Jul 24;12 (7):e0181893.


Intergenerational impact of paternal lifetime exposures to both folic acid deficiency and supplementation on reproductive outcomes and imprinted gene methylation.

Ly L, Chan D, Aarabi M, Landry M, Behan NA, MacFarlane AJ, Trasler J.

Mol Hum Reprod. 2017 Jul 1;23(7):461-477. doi: 10.1093/molehr/gax029.


Fascia iliaca block for hip replacement - adjuvants and ethics. A reply.

Kearns R, Macfarlane A, Kinsella J, Anderson K.

Anaesthesia. 2017 May;72(5):660-661. doi: 10.1111/anae.13881. No abstract available.


B-vitamin and choline supplementation increases neuroplasticity and recovery after stroke.

Jadavji NM, Emmerson JT, MacFarlane AJ, Willmore WG, Smith PD.

Neurobiol Dis. 2017 Jul;103:89-100. doi: 10.1016/j.nbd.2017.04.001. Epub 2017 Apr 7.


Exploring barriers to primary care for migrants in Greece in times of austerity: Perspectives of service providers.

Papadakaki M, Lionis C, Saridaki A, Dowrick C, de Brún T, O'Reilly-de Brún M, O'Donnell CA, Burns N, van Weel-Baumgarten E, van den Muijsenbergh M, Spiegel W, MacFarlane A.

Eur J Gen Pract. 2017 Dec;23(1):128-134. doi: 10.1080/13814788.2017.1307336.


Total folate and unmetabolized folic acid in the breast milk of a cross-section of Canadian women.

Page R, Robichaud A, Arbuckle TE, Fraser WD, MacFarlane AJ.

Am J Clin Nutr. 2017 May;105(5):1101-1109. doi: 10.3945/ajcn.116.137968. Epub 2017 Mar 15.


Implementing guidelines and training initiatives to improve cross-cultural communication in primary care consultations: a qualitative participatory European study.

Teunissen E, Gravenhorst K, Dowrick C, Van Weel-Baumgarten E, Van den Driessen Mareeuw F, de Brún T, Burns N, Lionis C, Mair FS, O'Donnell C, O'Reilly-de Brún M, Papadakaki M, Saridaki A, Spiegel W, Van Weel C, Van den Muijsenbergh M, MacFarlane A.

Int J Equity Health. 2017 Feb 10;16(1):32. doi: 10.1186/s12939-017-0525-y.


Fascia iliaca block for primary hip arthroplasty - a reply.

Kearns R, Macfarlane A, Kinsella J, Anderson K.

Anaesthesia. 2017 Mar;72(3):409-410. doi: 10.1111/anae.13825. No abstract available.


The economic costs of intrapartum care in Tower Hamlets: A comparison between the cost of birth in a freestanding midwifery unit and hospital for women at low risk of obstetric complications.

Schroeder L, Patel N, Keeler M, Rocca-Ihenacho L, Macfarlane AJ.

Midwifery. 2017 Feb;45:28-35. doi: 10.1016/j.midw.2016.11.006. Epub 2016 Nov 21.


Options for basing Dietary Reference Intakes (DRIs) on chronic disease endpoints: report from a joint US-/Canadian-sponsored working group.

Yetley EA, MacFarlane AJ, Greene-Finestone LS, Garza C, Ard JD, Atkinson SA, Bier DM, Carriquiry AL, Harlan WR, Hattis D, King JC, Krewski D, O'Connor DL, Prentice RL, Rodricks JV, Wells GA.

Am J Clin Nutr. 2017 Jan;105(1):249S-285S. doi: 10.3945/ajcn.116.139097. Epub 2016 Dec 7. Review.


Cardiovascular perturbations in high-intensity exercise. Can you exercise too hard?

Cartledge JE, James T, Macfarlane A.

J Physiol. 2016 Dec 1;594(23):6813-6814. doi: 10.1113/JP273019. No abstract available.


Authors' reply re: Wide differences in mode of delivery within Europe: risk-stratified analyses of aggregated routine data from the Euro-Peristat study.

Macfarlane AJ, Blondel B, Mohangoo AD, Cuttini M, Nijhuis J, Novak Z, Ólafsdóttir HS, Zeitlin J; Euro-Peristat Scientific Committee.

BJOG. 2016 Dec;123(13):2231. doi: 10.1111/1471-0528.14140. No abstract available.


Do primary care professionals agree about progress with implementation of primary care teams: results from a cross sectional study.

Tierney E, O'Sullivan M, Hickey L, Hannigan A, May C, Cullen W, Kennedy N, Kineen L, MacFarlane A.

BMC Fam Pract. 2016 Nov 22;17(1):163.


Consent for anaesthesia-sleepwalking into trouble.

Basler MH, Macfarlane AJ, McKinlay S.

BMJ. 2016 Nov 21;355:i6189. doi: 10.1136/bmj.i6189. No abstract available.


The elephant in the room: using nutritional biomarker cutoffs to assess status.

MacFarlane AJ.

Am J Clin Nutr. 2016 Dec;104(6):1493-1494. Epub 2016 Nov 16. No abstract available.


Murine MTHFD1-synthetase deficiency, a model for the human MTHFD1 R653Q polymorphism, decreases growth of colorectal tumors.

Lévesque N, Christensen KE, Van Der Kraak L, Best AF, Deng L, Caldwell D, MacFarlane AJ, Beauchemin N, Rozen R.

Mol Carcinog. 2017 Mar;56(3):1030-1040. doi: 10.1002/mc.22568. Epub 2016 Nov 1.


A randomised, controlled, double blind, non-inferiority trial of ultrasound-guided fascia iliaca block vs. spinal morphine for analgesia after primary hip arthroplasty.

Kearns R, Macfarlane A, Grant A, Puxty K, Harrison P, Shaw M, Anderson K, Kinsella J.

Anaesthesia. 2016 Dec;71(12):1431-1440. doi: 10.1111/anae.13620. Epub 2016 Oct 7.


Prospective controlled cohort study of Troponin I levels in patients undergoing elective spine surgery for degenerative conditions: Prone versus supine position.

Macfarlane AI, Rudd D, Knight E, Marshman LA, Guazzo EP, Anderson DS.

J Clin Neurosci. 2017 Jan;35:62-66. doi: 10.1016/j.jocn.2016.09.008. Epub 2016 Oct 1.


Participatory methods for research prioritization in primary care: an analysis of the World Café approach in Ireland and the USA.

MacFarlane A, Galvin R, O'Sullivan M, McInerney C, Meagher E, Burke D, LeMaster JW.

Fam Pract. 2017 Jun 1;34(3):278-284. doi: 10.1093/fampra/cmw104.


Estimating the Relative Sociolinguistic Salience of Segmental Variables in a Dialect Boundary Zone.

Llamas C, Watt D, MacFarlane AE.

Front Psychol. 2016 Aug 15;7:1163. doi: 10.3389/fpsyg.2016.01163. eCollection 2016.


Effect of regional versus local anaesthesia on outcome after arteriovenous fistula creation: a randomised controlled trial.

Aitken E, Jackson A, Kearns R, Steven M, Kinsella J, Clancy M, Macfarlane A.

Lancet. 2016 Sep 10;388(10049):1067-1074. doi: 10.1016/S0140-6736(16)30948-5. Epub 2016 Aug 1.


Learning from doing: the case for combining normalisation process theory and participatory learning and action research methodology for primary healthcare implementation research.

de Brún T, O'Reilly-de Brún M, O'Donnell CA, MacFarlane A.

BMC Health Serv Res. 2016 Aug 3;16(a):346. doi: 10.1186/s12913-016-1587-z.


Engaging migrants and other stakeholders to improve communication in cross-cultural consultation in primary care: a theoretically informed participatory study.

Lionis C, Papadakaki M, Saridaki A, Dowrick C, O'Donnell CA, Mair FS, van den Muijsenbergh M, Burns N, de Brún T, O'Reilly de Brún M, van Weel-Baumgarten E, Spiegel W, MacFarlane A.

BMJ Open. 2016 Jul 22;6(7):e010822. doi: 10.1136/bmjopen-2015-010822.


Serum and red-blood-cell folate demonstrate differential associations with BMI in pregnant women.

Shen M, Chaudhry SH, MacFarlane AJ, Gaudet L, Smith GN, Rodger M, White RR, Walker MC, Wen SW.

Public Health Nutr. 2016 Oct;19(14):2572-9. doi: 10.1017/S1368980016000756. Epub 2016 Apr 18.


Reducing the health care burden for marginalised migrants: The potential role for primary care in Europe.

O'Donnell CA, Burns N, Mair FS, Dowrick C, Clissmann C, van den Muijsenbergh M, van Weel-Baumgarten E, Lionis C, Papadakaki M, Saridaki A, de Brun T, MacFarlane A; RESTORE Team.

Health Policy. 2016 May;120(5):495-508. doi: 10.1016/j.healthpol.2016.03.012. Epub 2016 Apr 6. Review.


Correction: Cutting Edge: Role of NK Cells and Surfactant Protein D in Dendritic Cell Lymph Node Homing: Effects of Ozone Exposure.

Ge MQ, Kokalari B, Flayer CH, Killingbeck SS, Redai IG, MacFarlane AW 4th, Hwang JW, Kolupoti A, Kemeny DM, Campbell KS, Haczku A.

J Immunol. 2016 Apr 1;196(7):3212. doi: 10.4049/jimmunol.1600095. No abstract available.


Effectiveness of Subcutaneous Methotrexate in Chronic Plaque Psoriasis.

Yesudian PD, Leman J, Balasubramaniam P, Macfarlane AW, Al-Niaimi F, Griffiths CE, Burden AD, Warren RB.

J Drugs Dermatol. 2016 Mar;15(3):345-9.


Variations in Multiple Birth Rates and Impact on Perinatal Outcomes in Europe.

Heino A, Gissler M, Hindori-Mohangoo AD, Blondel B, Klungsøyr K, Verdenik I, Mierzejewska E, Velebil P, Sól Ólafsdóttir H, Macfarlane A, Zeitlin J; Euro-Peristat Scientific Committee.

PLoS One. 2016 Mar 1;11(3):e0149252. doi: 10.1371/journal.pone.0149252. eCollection 2016.


Linking databases on perinatal health: a review of the literature and current practices in Europe.

Delnord M, Szamotulska K, Hindori-Mohangoo AD, Blondel B, Macfarlane AJ, Dattani N, Barona C, Berrut S, Zile I, Wood R, Sakkeus L, Gissler M, Zeitlin J; Euro-Peristat Scientific Committee.

Eur J Public Health. 2016 Jun;26(3):422-30. doi: 10.1093/eurpub/ckv231. Epub 2016 Jan 10. Review.


Socioeconomic inequalities in stillbirth rates in Europe: measuring the gap using routine data from the Euro-Peristat Project.

Zeitlin J, Mortensen L, Prunet C, Macfarlane A, Hindori-Mohangoo AD, Gissler M, Szamotulska K, van der Pal K, Bolumar F, Andersen AM, Ólafsdóttir HS, Zhang WH, Blondel B, Alexander S; Euro-Peristat Scientific Committee.

BMC Pregnancy Childbirth. 2016 Jan 19;16:15. doi: 10.1186/s12884-016-0804-4.


Using Participatory Learning & Action research to access and engage with 'hard to reach' migrants in primary healthcare research.

O'Reilly-de Brún M, de Brún T, Okonkwo E, Bonsenge-Bokanga JS, De Almeida Silva MM, Ogbebor F, Mierzejewska A, Nnadi L, van Weel-Baumgarten E, van Weel C, van den Muijsenbergh M, MacFarlane A.

BMC Health Serv Res. 2016 Jan 20;16:25. doi: 10.1186/s12913-015-1247-8.


mTOR-Dependent and Independent Survival Signaling by PI3K in B Lymphocytes.

Kaileh M, Vazquez E, MacFarlane AW 4th, Campbell K, Kurosaki T, Siebenlist U, Sen R.

PLoS One. 2016 Jan 19;11(1):e0146955. doi: 10.1371/journal.pone.0146955. eCollection 2016.

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