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Items: 1 to 50 of 101

1.

Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6.

Hoepken HH, Gispert S, Morales B, Wingerter O, Del Turco D, Mülsch A, Nussbaum RL, Müller K, Dröse S, Brandt U, Deller T, Wirth B, Kudin AP, Kunz WS, Auburger G.

Neurobiol Dis. 2007 Feb;25(2):401-11. Epub 2006 Nov 30.

PMID:
17141510
2.

Nebivolol inhibits superoxide formation by NADPH oxidase and endothelial dysfunction in angiotensin II-treated rats.

Oelze M, Daiber A, Brandes RP, Hortmann M, Wenzel P, Hink U, Schulz E, Mollnau H, von Sandersleben A, Kleschyov AL, Mülsch A, Li H, Förstermann U, Münzel T.

Hypertension. 2006 Oct;48(4):677-84. Epub 2006 Aug 28.

3.

Mechanisms underlying dysfunction of carotid arteries in genetically hyperlipidemic rabbits.

August M, Wingerter O, Oelze M, Wenzel P, Kleschyov AL, Daiber A, Mülsch A, Münzel T, Tsilimingas N.

Nitric Oxide. 2006 Nov;15(3):241-51. Epub 2006 Apr 4.

PMID:
16597505
4.

Biochemistry and pharmacology of novel anthranilic acid derivatives activating heme-oxidized soluble guanylyl cyclase.

Schindler U, Strobel H, Schönafinger K, Linz W, Löhn M, Martorana PA, Rütten H, Schindler PW, Busch AE, Sohn M, Töpfer A, Pistorius A, Jannek C, Mülsch A.

Mol Pharmacol. 2006 Apr;69(4):1260-8. Epub 2005 Dec 6.

5.

Hydralazine is a powerful inhibitor of peroxynitrite formation as a possible explanation for its beneficial effects on prognosis in patients with congestive heart failure.

Daiber A, Oelze M, Coldewey M, Kaiser K, Huth C, Schildknecht S, Bachschmid M, Nazirisadeh Y, Ullrich V, Mülsch A, Münzel T, Tsilimingas N.

Biochem Biophys Res Commun. 2005 Dec 30;338(4):1865-74. Epub 2005 Nov 11.

PMID:
16289107
6.

Nitric oxide down-regulates the expression of the catalytic NADPH oxidase subunit Nox1 in rat renal mesangial cells.

Plesková M, Beck KF, Behrens MH, Huwiler A, Fichtlscherer B, Wingerter O, Brandes RP, Mülsch A, Pfeilschifter J.

FASEB J. 2006 Jan;20(1):139-41. Epub 2005 Oct 27.

PMID:
16254042
7.

The oxidative stress concept of nitrate tolerance and the antioxidant properties of hydralazine.

Daiber A, Mülsch A, Hink U, Mollnau H, Warnholtz A, Oelze M, Münzel T.

Am J Cardiol. 2005 Oct 10;96(7B):25i-36i. Epub 2005 Aug 8. Review.

PMID:
16226933
8.

Explaining the phenomenon of nitrate tolerance.

Münzel T, Daiber A, Mülsch A.

Circ Res. 2005 Sep 30;97(7):618-28. Review.

9.

Differential effects of diabetes on the expression of the gp91phox homologues nox1 and nox4.

Wendt MC, Daiber A, Kleschyov AL, Mülsch A, Sydow K, Schulz E, Chen K, Keaney JF Jr, Lassègue B, Walter U, Griendling KK, Münzel T.

Free Radic Biol Med. 2005 Aug 1;39(3):381-91. Epub 2005 Apr 7.

PMID:
15993337
10.

Heterozygous deficiency of manganese superoxide dismutase in mice (Mn-SOD+/-): a novel approach to assess the role of oxidative stress for the development of nitrate tolerance.

Daiber A, Oelze M, Sulyok S, Coldewey M, Schulz E, Treiber N, Hink U, Mülsch A, Scharffetter-Kochanek K, Münzel T.

Mol Pharmacol. 2005 Sep;68(3):579-88. Epub 2005 Jun 2.

11.

Human-antigen R (HuR) expression in hypertension: downregulation of the mRNA stabilizing protein HuR in genetic hypertension.

Klöss S, Rodenbach D, Bordel R, Mülsch A.

Hypertension. 2005 Jun;45(6):1200-6. Epub 2005 May 9.

12.

Vascular consequences of endothelial nitric oxide synthase uncoupling for the activity and expression of the soluble guanylyl cyclase and the cGMP-dependent protein kinase.

Münzel T, Daiber A, Ullrich V, Mülsch A.

Arterioscler Thromb Vasc Biol. 2005 Aug;25(8):1551-7. Epub 2005 May 5. Review.

13.

Oxidative stress and mitochondrial aldehyde dehydrogenase activity: a comparison of pentaerythritol tetranitrate with other organic nitrates.

Daiber A, Oelze M, Coldewey M, Bachschmid M, Wenzel P, Sydow K, Wendt M, Kleschyov AL, Stalleicken D, Ullrich V, Mülsch A, Münzel T.

Mol Pharmacol. 2004 Dec;66(6):1372-82. Epub 2004 Aug 26.

14.
15.

Central role of mitochondrial aldehyde dehydrogenase and reactive oxygen species in nitroglycerin tolerance and cross-tolerance.

Sydow K, Daiber A, Oelze M, Chen Z, August M, Wendt M, Ullrich V, Mülsch A, Schulz E, Keaney JF Jr, Stamler JS, Münzel T.

J Clin Invest. 2004 Feb;113(3):482-9.

16.

Physiology and pathophysiology of vascular signaling controlled by guanosine 3',5'-cyclic monophosphate-dependent protein kinase [corrected].

Münzel T, Feil R, Mülsch A, Lohmann SM, Hofmann F, Walter U.

Circulation. 2003 Nov 4;108(18):2172-83. Review. No abstract available. Erratum in: Circulation. 2003 Dec 23;108(25):3165.

17.

Amlodipine activates the endothelial nitric oxide synthase by altering phosphorylation on Ser1177 and Thr495.

Lenasi H, Kohlstedt K, Fichtlscherer B, Mülsch A, Busse R, Fleming I.

Cardiovasc Res. 2003 Oct 1;59(4):844-53.

PMID:
14553824
18.

Does nitric oxide mediate the vasodilator activity of nitroglycerin?

Kleschyov AL, Oelze M, Daiber A, Huang Y, Mollnau H, Schulz E, Sydow K, Fichtlscherer B, Mülsch A, Münzel T.

Circ Res. 2003 Oct 31;93(9):e104-12. Epub 2003 Oct 9.

19.

Post-transcriptional regulation of soluble guanylyl cyclase expression in rat aorta.

Kloss S, Furneaux H, Mülsch A.

J Biol Chem. 2003 Jan 24;278(4):2377-83. Epub 2002 Nov 18.

20.

Mechanisms underlying nitroglycerin-induced superoxide production in platelets: some insight, more questions.

Münzel T, Mülsch A, Kleschyov A.

Circulation. 2002 Jul 9;106(2):170-2. No abstract available.

21.

The effect of peroxynitrite on the catalytic activity of soluble guanylyl cyclase.

Weber M, Lauer N, Mülsch A, Kojda G.

Free Radic Biol Med. 2001 Dec 1;31(11):1360-7.

PMID:
11728807
22.

Effects of in vivo nitroglycerin treatment on activity and expression of the guanylyl cyclase and cGMP-dependent protein kinase and their downstream target vasodilator-stimulated phosphoprotein in aorta.

Mülsch A, Oelze M, Klöss S, Mollnau H, Töpfer A, Smolenski A, Walter U, Stasch JP, Warnholtz A, Hink U, Meinertz T, Münzel T.

Circulation. 2001 May 1;103(17):2188-94.

23.

MR imaging of nitrosyl-iron complexes: experimental study in rats.

Fichtlscherer B, Mülsch A.

Radiology. 2000 Jul;216(1):225-31.

PMID:
10887252
24.

Increased nitrovasodilator sensitivity in endothelial nitric oxide synthase knockout mice: role of soluble guanylyl cyclase.

Brandes RP, Kim D, Schmitz-Winnenthal FH, Amidi M, Gödecke A, Mülsch A, Busse R.

Hypertension. 2000 Jan;35(1 Pt 2):231-6.

25.

Aging and chronic hypertension decrease expression of rat aortic soluble guanylyl cyclase.

Klöss S, Bouloumié A, Mülsch A.

Hypertension. 2000 Jan;35(1 Pt 1):43-7.

26.

Detection of nitrosyl-iron complexes by proton-electron-double-resonance imaging.

Mülsch A, Lurie DJ, Seimenis I, Fichtlscherer B, Foster MA.

Free Radic Biol Med. 1999 Sep;27(5-6):636-46.

PMID:
10490285
27.

Role of superoxide dismutase in in vivo and in vitro nitrate tolerance.

Münzel T, Hink U, Yigit H, Macharzina R, Harrison DG, Mülsch A.

Br J Pharmacol. 1999 Jul;127(5):1224-30.

28.

Nitric oxide inhibits caspase-3 by S-nitrosation in vivo.

Rössig L, Fichtlscherer B, Breitschopf K, Haendeler J, Zeiher AM, Mülsch A, Dimmeler S.

J Biol Chem. 1999 Mar 12;274(11):6823-6.

29.

Validation of lucigenin as a chemiluminescent probe to monitor vascular superoxide as well as basal vascular nitric oxide production.

Skatchkov MP, Sperling D, Hink U, Mülsch A, Harrison DG, Sindermann I, Meinertz T, Münzel T.

Biochem Biophys Res Commun. 1999 Jan 19;254(2):319-24.

PMID:
9918836
30.

Normoxic cardiopulmonary bypass reduces oxidative myocardial damage and nitric oxide during cardiac operations in the adult.

Ihnken K, Winkler A, Schlensak C, Sarai K, Neidhart G, Unkelbach U, Mülsch A, Sewell A.

J Thorac Cardiovasc Surg. 1998 Aug;116(2):327-34.

31.
32.

Characterization of NS 2028 as a specific inhibitor of soluble guanylyl cyclase.

Olesen SP, Drejer J, Axelsson O, Moldt P, Bang L, Nielsen-Kudsk JE, Busse R, Mülsch A.

Br J Pharmacol. 1998 Jan;123(2):299-309.

33.

Dinitrosyl-dithiol-iron complexes, nitric oxide (NO) carriers in vivo, as potent inhibitors of human glutathione reductase and glutathione-S-transferase.

Keese MA, Böse M, Mülsch A, Schirmer RH, Becker K.

Biochem Pharmacol. 1997 Dec 15;54(12):1307-13.

PMID:
9393673
34.

Inhibition of glutathione reductase by dinitrosyl-iron-dithiolate complex.

Boese M, Keese MA, Becker K, Busse R, Mülsch A.

J Biol Chem. 1997 Aug 29;272(35):21767-73.

35.

Regional measurements of NO formed in vivo during brain ischemia.

Olesen SP, Møller A, Mordvintcev PI, Busse R, Mülsch A.

Acta Neurol Scand. 1997 Apr;95(4):219-24.

PMID:
9150812
36.

N-alpha-tosyl-L-lysine chloromethylketone prevents expression of iNOS in vascular smooth muscle by blocking activation of NF-kappa B.

Schini-Kerth VB, Boese M, Busse R, Fisslthaler B, Mülsch A.

Arterioscler Thromb Vasc Biol. 1997 Apr;17(4):672-9.

37.
38.

In vivo nitrate tolerance is not associated with reduced bioconversion of nitroglycerin to nitric oxide.

Laursen JB, Mülsch A, Boesgaard S, Mordvintcev P, Trautner S, Gruhn N, Nielsen-Kudsk JE, Busse R, Aldershvile J.

Circulation. 1996 Nov 1;94(9):2241-7.

40.

S-nitrosation of serum albumin by dinitrosyl-iron complex.

Boese M, Mordvintcev PI, Vanin AF, Busse R, Mülsch A.

J Biol Chem. 1995 Dec 8;270(49):29244-9.

41.

Specificity of different organic nitrates to elicit NO formation in rabbit vascular tissues and organs in vivo.

Mülsch A, Bara A, Mordvintcev P, Vanin A, Busse R.

Br J Pharmacol. 1995 Nov;116(6):2743-9.

42.

In vivo spin trapping of glyceryl trinitrate-derived nitric oxide in rabbit blood vessels and organs.

Mülsch A, Mordvintcev P, Bassenge E, Jung F, Clement B, Busse R.

Circulation. 1995 Oct 1;92(7):1876-82.

44.
45.

Synthesis of 15N omega-hydroxy-L-arginine and ESR and 15N-NMR studies for the elucidation of the molecular mechanism of enzymic nitric oxide formation from L-arginine.

Clement B, Schnörwangen E, Kämpchen T, Mordvintcev P, Mülsch A.

Arch Pharm (Weinheim). 1994 Dec;327(12):793-8.

PMID:
7532937
46.

Nitric oxide promotes seizure activity in kainate-treated rats.

Mülsch A, Busse R, Mordvintcev PI, Vanin AF, Nielsen EO, Scheel-Krüger J, Olesen SP.

Neuroreport. 1994 Nov 21;5(17):2325-8.

PMID:
7533556
47.

Pyrrolidine dithiocarbamate selectively prevents the expression of the inducible nitric oxide synthase in the rat aorta.

Schini-Kerth V, Bara A, Mülsch A, Busse R.

Eur J Pharmacol. 1994 Nov 14;265(1-2):83-7.

PMID:
7533726
48.

Epr evidence of nitric oxide production by the regenerating rat liver.

Obolenskaya MYu, Vanin AF, Mordvintcev PI, Mülsch A, Decker K.

Biochem Biophys Res Commun. 1994 Jul 15;202(1):571-6. Erratum in: Biochem Biophys Res Commun 1994 Aug 30;203(1):743.

PMID:
8080556
49.

Subcellular localization and characterization of nitric oxide synthase(s) in endothelial cells: physiological implications.

Hecker M, Mülsch A, Bassenge E, Förstermann U, Busse R.

Biochem J. 1994 Apr 1;299 ( Pt 1):247-52.

50.

Subcellular localization and characterization of neuronal nitric oxide synthase.

Hecker M, Mülsch A, Busse R.

J Neurochem. 1994 Apr;62(4):1524-9.

PMID:
7510784

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