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Items: 1 to 50 of 475

1.

Correction to: Imipenem-Relebactam and Meropenem-Vaborbactam: Two Novel Carbapenem-β-Lactamase Inhibitor Combinations.

Zhanel GG, Lawrence CK, Adam H, Schweizer F, Zelenitsky S, Zhanel M, Lagacé-Wiens PRS, Walkty A, Denisuik A, Golden A, Gin AS, Hoban DJ, Lynch JP 3rd, Karlowsky JA.

Drugs. 2018 May 10. doi: 10.1007/s40265-018-0910-x. [Epub ahead of print]

PMID:
29748749
2.

PGD2/DP2 receptor activation promotes severe viral bronchiolitis by suppressing IFN-λ production.

Werder RB, Lynch JP, Simpson JC, Zhang V, Hodge NH, Poh M, Forbes-Blom E, Kulis C, Smythe ML, Upham JW, Spann K, Everard ML, Phipps S.

Sci Transl Med. 2018 May 9;10(440). pii: eaao0052. doi: 10.1126/scitranslmed.aao0052.

PMID:
29743346
3.

Author Correction: A mechanistic framework for auxin dependent Arabidopsis root hair elongation to low external phosphate.

Bhosale R, Giri J, Pandey BK, Giehl RFH, Hartmann A, Traini R, Truskina J, Leftley N, Hanlon M, Swarup K, Rashed A, Voß U, Alonso J, Stepanova A, Yun J, Ljung K, Brown KM, Lynch JP, Dolan L, Vernoux T, Bishopp A, Wells D, von Wirén N, Bennett MJ, Swarup R.

Nat Commun. 2018 May 2;9(1):1818. doi: 10.1038/s41467-018-04281-x.

4.

A mechanistic framework for auxin dependent Arabidopsis root hair elongation to low external phosphate.

Bhosale R, Giri J, Pandey BK, Giehl RFH, Hartmann A, Traini R, Truskina J, Leftley N, Hanlon M, Swarup K, Rashed A, Voß U, Alonso J, Stepanova A, Yun J, Ljung K, Brown KM, Lynch JP, Dolan L, Vernoux T, Bishopp A, Wells D, von Wirén N, Bennett MJ, Swarup R.

Nat Commun. 2018 Apr 12;9(1):1409. doi: 10.1038/s41467-018-03851-3. Erratum in: Nat Commun. 2018 May 2;9(1):1818.

5.

Large Crown Root Number Improves Topsoil Foraging and Phosphorus Acquisition.

Sun B, Gao Y, Lynch JP.

Plant Physiol. 2018 May;177(1):90-104. doi: 10.1104/pp.18.00234. Epub 2018 Apr 4.

6.

Fungal Infections Complicating Lung Transplantation.

Clark NM, Weigt SS, Fishbein MC, Kubak B, Belperio JA, Lynch JP 3rd.

Semin Respir Crit Care Med. 2018 Apr;39(2):227-254. doi: 10.1055/s-0037-1617443. Epub 2018 Mar 26.

PMID:
29579774
7.

Chronic Lung Allograft Dysfunction: Evolving Concepts and Therapies.

DerHovanessian A, Wallace WD, Lynch JP 3rd, Belperio JA, Weigt SS.

Semin Respir Crit Care Med. 2018 Apr;39(2):155-171. doi: 10.1055/s-0037-1618567. Epub 2018 Mar 26.

PMID:
29579768
8.

Reduced root cortical burden improves growth and grain yield under low phosphorus availability in maize.

Galindo-Castañeda T, Brown KM, Lynch JP.

Plant Cell Environ. 2018 Mar 25. doi: 10.1111/pce.13197. [Epub ahead of print]

PMID:
29574982
9.

Pulmonary Allograft Versus Host Disease.

Dai DW, Garber B, Weigt SS, Worswick S, Kubak BM, Lynch JP 3rd, Shino MY, DerHovanessian A, Saggar R, Ross DJ, Sayah DM.

Transplant Direct. 2017 Nov 20;3(12):e333. doi: 10.1097/TXD.0000000000000749. eCollection 2017 Dec. No abstract available.

10.

Rightsizing Root Phenotypes for Drought resistance.

Lynch JP.

J Exp Bot. 2018 Feb 17. doi: 10.1093/jxb/ery048. [Epub ahead of print]

PMID:
29471525
11.

Buffered delivery of phosphate to Arabidopsis alters responses to low phosphate.

Hanlon MT, Ray S, Saengwilai P, Luthe D, Lynch JP, Brown KM.

J Exp Bot. 2018 Jan 3. doi: 10.1093/jxb/erx454. [Epub ahead of print]

PMID:
29304231
12.

Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion.

Lynch JP, Werder RB, Loh Z, Sikder MAA, Curren B, Zhang V, Rogers MJ, Lane K, Simpson J, Mazzone SB, Spann K, Hayball J, Diener K, Everard ML, Blyth CC, Forstner C, Dennis PG, Murtaza N, Morrison M, Ó Cuív P, Zhang P, Haque A, Hill GR, Sly PD, Upham JW, Phipps S.

J Exp Med. 2018 Feb 5;215(2):537-557. doi: 10.1084/jem.20170298. Epub 2017 Dec 22.

PMID:
29273643
13.

GUCY2C maintains intestinal LGR5+ stem cells by opposing ER stress.

Kraft CL, Rappaport JA, Snook AE, Pattison AM, Lynch JP, Waldman SA.

Oncotarget. 2017 Oct 26;8(61):102923-102933. doi: 10.18632/oncotarget.22084. eCollection 2017 Nov 28.

14.

Gene Expression Profiling of Bronchoalveolar Lavage Cells During Aspergillus Colonization of the Lung Allograft.

Weigt SS, Wang X, Palchevskiy V, Patel N, Derhovanessian A, Shino MY, Sayah DM, Lynch JP 3rd, Saggar R, Ross DJ, Kubak BM, Ardehali A, Palmer S, Husain S, Belperio JA.

Transplantation. 2018 Jun;102(6):986-993. doi: 10.1097/TP.0000000000002058.

PMID:
29256975
15.

Imipenem-Relebactam and Meropenem-Vaborbactam: Two Novel Carbapenem-β-Lactamase Inhibitor Combinations.

Zhanel GG, Lawrence CK, Adam H, Schweizer F, Zelenitsky S, Zhanel M, Lagacé-Wiens PRS, Walkty A, Denisuik A, Golden A, Gin AS, Hoban DJ, Lynch JP 3rd, Karlowsky JA.

Drugs. 2018 Jan;78(1):65-98. doi: 10.1007/s40265-017-0851-9. Review. Erratum in: Drugs. 2018 May 10;:.

PMID:
29230684
16.

Critical Role of Plasmacytoid Dendritic Cells in Regulating Gene Expression and Innate Immune Responses to Human Rhinovirus-16.

Xi Y, Troy NM, Anderson D, Pena OM, Lynch JP, Phipps S, Bosco A, Upham JW.

Front Immunol. 2017 Oct 25;8:1351. doi: 10.3389/fimmu.2017.01351. eCollection 2017.

17.

Reduction in Root Secondary Growth as a Strategy for Phosphorus Acquisition.

Strock CF, Morrow de la Riva L, Lynch JP.

Plant Physiol. 2018 Jan;176(1):691-703. doi: 10.1104/pp.17.01583. Epub 2017 Nov 8.

18.

Pulmonary Hypertension Complicating Connective Tissue Disease.

Volkmann ER, Chung A, Saggar R, Belperio JA, Lynch JP 3rd.

Semin Respir Crit Care Med. 2017 Oct;38(5):619-635. doi: 10.1055/s-0037-1606203. Epub 2017 Oct 15. No abstract available.

PMID:
29032565
19.

Chronic IL-33 expression predisposes to virus-induced asthma exacerbations by increasing type 2 inflammation and dampening antiviral immunity.

Werder RB, Zhang V, Lynch JP, Snape N, Upham JW, Spann K, Phipps S.

J Allergy Clin Immunol. 2018 May;141(5):1607-1619.e9. doi: 10.1016/j.jaci.2017.07.051. Epub 2017 Sep 22.

PMID:
28947081
20.

Gene Expression Profiling of Bronchoalveolar Lavage Cells Preceding a Clinical Diagnosis of Chronic Lung Allograft Dysfunction.

Weigt SS, Wang X, Palchevskiy V, Patel N, Derhovanessian A, Shino MY, Sayah DM, Gregson AL, Lynch JP 3rd, Saggar R, Ross DJ, Ardehali A, Elashoff D, Belperio JA.

Ann Am Thorac Soc. 2017 Sep;14(Supplement_3):S252. doi: 10.1513/AnnalsATS.201608-618MG. No abstract available.

PMID:
28945470
21.

Shaping 3D Root System Architecture.

Morris EC, Griffiths M, Golebiowska A, Mairhofer S, Burr-Hersey J, Goh T, von Wangenheim D, Atkinson B, Sturrock CJ, Lynch JP, Vissenberg K, Ritz K, Wells DM, Mooney SJ, Bennett MJ.

Curr Biol. 2017 Sep 11;27(17):R919-R930. doi: 10.1016/j.cub.2017.06.043. Review.

PMID:
28898665
22.

Cardiac Involvement in Sarcoidosis: Evolving Concepts in Diagnosis and Treatment.

Sayah DM, Bradfield JS, Moriarty JM, Belperio JA, Lynch JP 3rd.

Semin Respir Crit Care Med. 2017 Aug;38(4):477-498. doi: 10.1055/s-0037-1602381. Epub 2017 Jul 27. No abstract available.

PMID:
28750462
23.

Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity.

Yan KS, Gevaert O, Zheng GXY, Anchang B, Probert CS, Larkin KA, Davies PS, Cheng ZF, Kaddis JS, Han A, Roelf K, Calderon RI, Cynn E, Hu X, Mandleywala K, Wilhelmy J, Grimes SM, Corney DC, Boutet SC, Terry JM, Belgrader P, Ziraldo SB, Mikkelsen TS, Wang F, von Furstenberg RJ, Smith NR, Chandrakesan P, May R, Chrissy MAS, Jain R, Cartwright CA, Niland JC, Hong YK, Carrington J, Breault DT, Epstein J, Houchen CW, Lynch JP, Martin MG, Plevritis SK, Curtis C, Ji HP, Li L, Henning SJ, Wong MH, Kuo CJ.

Cell Stem Cell. 2017 Jul 6;21(1):78-90.e6. doi: 10.1016/j.stem.2017.06.014.

PMID:
28686870
24.

The prognostic importance of CXCR3 chemokine during organizing pneumonia on the risk of chronic lung allograft dysfunction after lung transplantation.

Shino MY, Weigt SS, Li N, Palchevskiy V, Derhovanessian A, Saggar R, Sayah DM, Huynh RH, Gregson AL, Fishbein MC, Ardehali A, Ross DJ, Lynch JP 3rd, Elashoff RM, Belperio JA.

PLoS One. 2017 Jul 7;12(7):e0180281. doi: 10.1371/journal.pone.0180281. eCollection 2017.

25.

Root Cortical Senescence Improves Growth under Suboptimal Availability of N, P, and K.

Schneider HM, Postma JA, Wojciechowski T, Kuppe C, Lynch JP.

Plant Physiol. 2017 Aug;174(4):2333-2347. doi: 10.1104/pp.17.00648. Epub 2017 Jun 30.

26.

Morphological Plant Modeling: Unleashing Geometric and Topological Potential within the Plant Sciences.

Bucksch A, Atta-Boateng A, Azihou AF, Battogtokh D, Baumgartner A, Binder BM, Braybrook SA, Chang C, Coneva V, DeWitt TJ, Fletcher AG, Gehan MA, Diaz-Martinez DH, Hong L, Iyer-Pascuzzi AS, Klein LL, Leiboff S, Li M, Lynch JP, Maizel A, Maloof JN, Markelz RJC, Martinez CC, Miller LA, Mio W, Palubicki W, Poorter H, Pradal C, Price CA, Puttonen E, Reese JB, Rellán-Álvarez R, Spalding EP, Sparks EE, Topp CN, Williams JH, Chitwood DH.

Front Plant Sci. 2017 Jun 9;8:900. doi: 10.3389/fpls.2017.00900. eCollection 2017. Review.

27.

OpenSimRoot: widening the scope and application of root architectural models.

Postma JA, Kuppe C, Owen MR, Mellor N, Griffiths M, Bennett MJ, Lynch JP, Watt M.

New Phytol. 2017 Aug;215(3):1274-1286. doi: 10.1111/nph.14641. Epub 2017 Jun 27.

28.

Modeling Esophagitis Using Human Three-Dimensional Organotypic Culture System.

Laczkó D, Wang F, Johnson FB, Jhala N, Rosztóczy A, Ginsberg GG, Falk GW, Rustgi AK, Lynch JP.

Am J Pathol. 2017 Aug;187(8):1787-1799. doi: 10.1016/j.ajpath.2017.04.013. Epub 2017 Jun 13.

PMID:
28627413
29.

Emergence of Antimicrobial Resistance among Pseudomonas aeruginosa: Implications for Therapy.

Lynch JP 3rd, Zhanel GG, Clark NM.

Semin Respir Crit Care Med. 2017 Jun;38(3):326-345. doi: 10.1055/s-0037-1602583. Epub 2017 Jun 4.

PMID:
28578556
30.

Infections Due to Acinetobacter baumannii in the ICU: Treatment Options.

Lynch JP 3rd, Zhanel GG, Clark NM.

Semin Respir Crit Care Med. 2017 Jun;38(3):311-325. doi: 10.1055/s-0037-1599225. Epub 2017 Jun 4.

PMID:
28578555
31.

Crops In Silico: Generating Virtual Crops Using an Integrative and Multi-scale Modeling Platform.

Marshall-Colon A, Long SP, Allen DK, Allen G, Beard DA, Benes B, von Caemmerer S, Christensen AJ, Cox DJ, Hart JC, Hirst PM, Kannan K, Katz DS, Lynch JP, Millar AJ, Panneerselvam B, Price ND, Prusinkiewicz P, Raila D, Shekar RG, Shrivastava S, Shukla D, Srinivasan V, Stitt M, Turk MJ, Voit EO, Wang Y, Yin X, Zhu XG.

Front Plant Sci. 2017 May 15;8:786. doi: 10.3389/fpls.2017.00786. eCollection 2017.

32.

The Absence of Interferon-β Promotor Stimulator-1 (IPS-1) Predisposes to Bronchiolitis and Asthma-like Pathology in Response to Pneumoviral Infection in Mice.

Simpson J, Lynch JP, Loh Z, Zhang V, Werder RB, Spann K, Phipps S.

Sci Rep. 2017 May 24;7(1):2353. doi: 10.1038/s41598-017-02564-9.

33.

Aspirin prevents NF-κB activation and CDX2 expression stimulated by acid and bile salts in oesophageal squamous cells of patients with Barrett's oesophagus.

Huo X, Zhang X, Yu C, Cheng E, Zhang Q, Dunbar KB, Pham TH, Lynch JP, Wang DH, Bresalier RS, Spechler SJ, Souza RF.

Gut. 2018 Apr;67(4):606-615. doi: 10.1136/gutjnl-2016-313584. Epub 2017 Apr 25.

34.

Mutual reinforcement between telomere capping and canonical Wnt signalling in the intestinal stem cell niche.

Yang TB, Chen Q, Deng JT, Jagannathan G, Tobias JW, Schultz DC, Wang S, Lengner CJ, Rustgi AK, Lynch JP, Johnson FB.

Nat Commun. 2017 Mar 17;8:14766. doi: 10.1038/ncomms14766.

35.

The Influence of the Microbiome on Early-Life Severe Viral Lower Respiratory Infections and Asthma-Food for Thought?

Lynch JP, Sikder MA, Curren BF, Werder RB, Simpson J, Cuív PÓ, Dennis PG, Everard ML, Phipps S.

Front Immunol. 2017 Feb 16;8:156. doi: 10.3389/fimmu.2017.00156. eCollection 2017. Review.

36.

Root cortical senescence decreases root respiration, nutrient content and radial water and nutrient transport in barley.

Schneider HM, Wojciechowski T, Postma JA, Brown KM, Lücke A, Zeisler V, Schreiber L, Lynch JP.

Plant Cell Environ. 2017 Aug;40(8):1392-1408. doi: 10.1111/pce.12933. Epub 2017 Apr 12.

PMID:
28164319
37.

Gene Expression Profiling of Bronchoalveolar Lavage Cells Preceding a Clinical Diagnosis of Chronic Lung Allograft Dysfunction.

Weigt SS, Wang X, Palchevskiy V, Gregson AL, Patel N, DerHovanessian A, Shino MY, Sayah DM, Birjandi S, Lynch JP 3rd, Saggar R, Ardehali A, Ross DJ, Palmer SM, Elashoff D, Belperio JA.

PLoS One. 2017 Jan 19;12(1):e0169894. doi: 10.1371/journal.pone.0169894. eCollection 2017.

38.

Solithromycin: A Novel Fluoroketolide for the Treatment of Community-Acquired Bacterial Pneumonia.

Zhanel GG, Hartel E, Adam H, Zelenitsky S, Zhanel MA, Golden A, Schweizer F, Gorityala B, Lagacé-Wiens PR, Walkty AJ, Gin AS, Hoban DJ, Lynch JP 3rd, Karlowsky JA.

Drugs. 2016 Dec;76(18):1737-1757. Review.

PMID:
27909995
39.

Th2/Th17 reciprocal regulation: twists and turns in the complexity of asthma phenotypes.

Lynch JP, Ferreira MA, Phipps S.

Ann Transl Med. 2016 Oct;4(Suppl 1):S59. No abstract available.

40.

Genome-wide association mapping and agronomic impact of cowpea root architecture.

Burridge JD, Schneider HM, Huynh BL, Roberts PA, Bucksch A, Lynch JP.

Theor Appl Genet. 2017 Feb;130(2):419-431. doi: 10.1007/s00122-016-2823-y. Epub 2016 Nov 18.

PMID:
27864597
41.

Impact of Allograft Injury Time of Onset on the Development of Chronic Lung Allograft Dysfunction After Lung Transplantation.

Shino MY, Weigt SS, Li N, Derhovanessian A, Sayah DM, Huynh RH, Saggar R, Gregson AL, Ardehali A, Ross DJ, Lynch JP 3rd, Elashoff RM, Belperio JA.

Am J Transplant. 2017 May;17(5):1294-1303. doi: 10.1111/ajt.14066. Epub 2016 Oct 31.

42.

Voriconazole increases the risk for cutaneous squamous cell carcinoma after lung transplantation.

Kolaitis NA, Duffy E, Zhang A, Lo M, Barba DT, Chen M, Soriano T, Hu J, Nabili V, Saggar R, Sayah DM, DerHovanessian A, Shino MY, Lynch JP 3rd, Kubak BM, Ardehali A, Ross DJ, Belperio JA, Elashoff D, Saggar R, Weigt SS.

Transpl Int. 2017 Jan;30(1):41-48. doi: 10.1111/tri.12865. Epub 2016 Oct 24.

43.

Graft Loss and CLAD-Onset Is Hastened by Viral Pneumonia After Lung Transplantation.

Allyn PR, Duffy EL, Humphries RM, Injean P, Weigt SS, Saggar R, Shino MY, Lynch JP 3rd, Ardehali A, Kubak B, Tseng CH, Belperio JA, Ross DJ, Gregson AL.

Transplantation. 2016 Nov;100(11):2424-2431.

44.

Emergence of antimicrobial resistance among Acinetobacter species: a global threat.

Clark NM, Zhanel GG, Lynch JP 3rd.

Curr Opin Crit Care. 2016 Oct;22(5):491-9. doi: 10.1097/MCC.0000000000000337. Review.

PMID:
27552304
45.

Herpesvirus Respiratory Infections in Immunocompromised Patients: Epidemiology, Management, and Outcomes.

Reid GE, Lynch JP 3rd, Weigt S, Sayah D, Belperio JA, Grim SA, Clark NM.

Semin Respir Crit Care Med. 2016 Aug;37(4):603-30. doi: 10.1055/s-0036-1584793. Epub 2016 Aug 3. Review.

PMID:
27486740
46.

Adenovirus: Epidemiology, Global Spread of Novel Serotypes, and Advances in Treatment and Prevention.

Lynch JP 3rd, Kajon AE.

Semin Respir Crit Care Med. 2016 Aug;37(4):586-602. doi: 10.1055/s-0036-1584923. Epub 2016 Aug 3. Review.

PMID:
27486739
47.

Intestinal Enteroids Model Guanylate Cyclase C-Dependent Secretion Induced by Heat-Stable Enterotoxins.

Pattison AM, Blomain ES, Merlino DJ, Wang F, Crissey MA, Kraft CL, Rappaport JA, Snook AE, Lynch JP, Waldman SA.

Infect Immun. 2016 Sep 19;84(10):3083-91. doi: 10.1128/IAI.00639-16. Print 2016 Oct.

48.

Impact of axial root growth angles on nitrogen acquisition in maize depends on environmental conditions.

Dathe A, Postma JA, Postma-Blaauw MB, Lynch JP.

Ann Bot. 2016 Sep;118(3):401-14. doi: 10.1093/aob/mcw112. Epub 2016 Jul 29.

49.

Association Between Germline Mutation in VSIG10L and Familial Barrett Neoplasia.

Fecteau RE, Kong J, Kresak A, Brock W, Song Y, Fujioka H, Elston R, Willis JE, Lynch JP, Markowitz SD, Guda K, Chak A.

JAMA Oncol. 2016 Oct 1;2(10):1333-1339. doi: 10.1001/jamaoncol.2016.2054.

50.

Reduced crown root number improves water acquisition under water deficit stress in maize (Zea mays L.).

Gao Y, Lynch JP.

J Exp Bot. 2016 Aug;67(15):4545-57. doi: 10.1093/jxb/erw243. Epub 2016 Jul 8.

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