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Items: 1 to 50 of 80

1.

Constant hepatic ATP concentrations during prolonged fasting and absence of effects of Cerbomed Nemos® on parasympathetic tone and hepatic energy metabolism.

Gancheva S, Bierwagen A, Markgraf DF, Bönhof GJ, Murphy KG, Hatziagelaki E, Lundbom J, Ziegler D, Roden M.

Mol Metab. 2018 Jan;7:71-79. doi: 10.1016/j.molmet.2017.10.002. Epub 2017 Oct 25.

2.

Physical activity, cardiorespiratory fitness, and metabolic outcomes in monozygotic twin pairs discordant for body mass index.

Berntzen B, Jukarainen S, Kataja M, Hakkarainen A, Lundbom J, Lundbom N, Tammelin T, Simonen R, Piirilä P, Rissanen A, Kaprio J, Paavonen EJ, Pietiläinen KH.

Scand J Med Sci Sports. 2018 Mar;28(3):1048-1055. doi: 10.1111/sms.12975. Epub 2017 Sep 21.

PMID:
28833625
3.

Adipose tissue and liver.

Lundbom J.

J Appl Physiol (1985). 2018 Jan 1;124(1):162-167. doi: 10.1152/japplphysiol.00399.2017. Epub 2017 Jul 6.

PMID:
28684589
4.

Metabolism of sex steroids is influenced by acquired adiposity-A study of young adult male monozygotic twin pairs.

Vihma V, Naukkarinen J, Turpeinen U, Hämäläinen E, Kaprio J, Rissanen A, Heinonen S, Hakkarainen A, Lundbom J, Lundbom N, Mikkola TS, Tikkanen MJ, Pietiläinen KH.

J Steroid Biochem Mol Biol. 2017 Sep;172:98-105. doi: 10.1016/j.jsbmb.2017.06.007. Epub 2017 Jun 13.

PMID:
28619249
5.

Upregulation of Early and Downregulation of Terminal Pathway Complement Genes in Subcutaneous Adipose Tissue and Adipocytes in Acquired Obesity.

Kaye S, Lokki AI, Hanttu A, Nissilä E, Heinonen S, Hakkarainen A, Lundbom J, Lundbom N, Saarinen L, Tynninen O, Muniandy M, Rissanen A, Kaprio J, Meri S, Pietiläinen KH.

Front Immunol. 2017 May 16;8:545. doi: 10.3389/fimmu.2017.00545. eCollection 2017.

6.

Gene expression profile of subcutaneous adipose tissue in BMI-discordant monozygotic twin pairs unravels molecular and clinical changes associated with sub-types of obesity.

Muniandy M, Heinonen S, Yki-Järvinen H, Hakkarainen A, Lundbom J, Lundbom N, Kaprio J, Rissanen A, Ollikainen M, Pietiläinen KH.

Int J Obes (Lond). 2017 Aug;41(8):1176-1184. doi: 10.1038/ijo.2017.95. Epub 2017 Apr 25.

PMID:
28439093
7.

Cardiorespiratory Fitness and Adiposity as Determinants of Metabolic Health-Pooled Analysis of Two Twin Cohorts.

Jukarainen S, Holst R, Dalgård C, Piirilä P, Lundbom J, Hakkarainen A, Lundbom N, Rissanen A, Kaprio J, Kyvik KO, Sørensen TIA, Pietiläinen KH.

J Clin Endocrinol Metab. 2017 May 1;102(5):1520-1528. doi: 10.1210/jc.2016-3435.

PMID:
28324016
8.

Personal model-assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD.

Mardinoglu A, Bjornson E, Zhang C, Klevstig M, Söderlund S, Ståhlman M, Adiels M, Hakkarainen A, Lundbom N, Kilicarslan M, Hallström BM, Lundbom J, Vergès B, Barrett PH, Watts GF, Serlie MJ, Nielsen J, Uhlén M, Smith U, Marschall HU, Taskinen MR, Boren J.

Mol Syst Biol. 2017 Mar 2;13(3):916. doi: 10.15252/msb.20167422.

9.

Liver Fat and Insulin Sensitivity Define Metabolite Profiles During a Glucose Tolerance Test in Young Adult Twins.

Rämö JT, Kaye SM, Jukarainen S, Bogl LH, Hakkarainen A, Lundbom J, Lundbom N, Rissanen A, Kaprio J, Matikainen N, Pietiläinen KH.

J Clin Endocrinol Metab. 2017 Jan 1;102(1):220-231. doi: 10.1210/jc.2015-3512.

PMID:
27809652
10.

Mitochondria-related transcriptional signature is downregulated in adipocytes in obesity: a study of young healthy MZ twins.

Heinonen S, Muniandy M, Buzkova J, Mardinoglu A, Rodríguez A, Frühbeck G, Hakkarainen A, Lundbom J, Lundbom N, Kaprio J, Rissanen A, Pietiläinen KH.

Diabetologia. 2017 Jan;60(1):169-181. Epub 2016 Oct 12.

PMID:
27734103
11.

The Influence of Injected Volume on Discomfort During Administration of Digital Block.

Ballo S, Hjelseng T, Tangen LF, Lundbom JS, Skarsvåg T, Finsen V.

J Hand Surg Asian Pac Vol. 2016 Oct;21(3):369-73. doi: 10.1142/S2424835516500363.

PMID:
27595956
12.

Deep subcutaneous adipose tissue lipid unsaturation associates with intramyocellular lipid content.

Lundbom J, Bierwagen A, Bodis K, Szendrödi J, Kaprio J, Rissanen A, Lundbom N, Roden M, Pietiläinen KH.

Metabolism. 2016 Sep;65(9):1230-7. doi: 10.1016/j.metabol.2016.05.010. Epub 2016 May 24.

PMID:
27506730
13.

The influence of Lidocaine temperature on pain during subcutaneous injection.

Lundbom JS, Tangen LF, Wågø KJ, Skarsvåg TI, Ballo S, Hjelseng T, Foss OA, Finsen V.

J Plast Surg Hand Surg. 2017 Apr;51(2):118-121. doi: 10.1080/2000656X.2016.1194281. Epub 2016 Jun 17.

PMID:
27314148
14.

Variants in Genes Controlling Oxidative Metabolism Contribute to Lower Hepatic ATP Independent of Liver Fat Content in Type 1 Diabetes.

Gancheva S, Bierwagen A, Kaul K, Herder C, Nowotny P, Kahl S, Giani G, Klueppelholz B, Knebel B, Begovatz P, Strassburger K, Al-Hasani H, Lundbom J, Szendroedi J, Roden M; German Diabetes Study (GDS) Group.

Diabetes. 2016 Jul;65(7):1849-57. doi: 10.2337/db16-0162. Epub 2016 Apr 19.

15.

Abdominal obesity and circulating metabolites: A twin study approach.

Bogl LH, Kaye SM, Rämö JT, Kangas AJ, Soininen P, Hakkarainen A, Lundbom J, Lundbom N, Ortega-Alonso A, Rissanen A, Ala-Korpela M, Kaprio J, Pietiläinen KH.

Metabolism. 2016 Mar;65(3):111-21. doi: 10.1016/j.metabol.2015.10.027. Epub 2015 Oct 31.

PMID:
26892522
16.

ApoA-II HDL Catabolism and Its Relationships With the Kinetics of ApoA-I HDL and of VLDL1, in Abdominal Obesity.

Vergès B, Adiels M, Boren J, Barrett PH, Watts GF, Chan D, Duvillard L, Söderlund S, Matikainen N, Kahri J, Lundbom N, Lundbom J, Hakkarainen A, Aho S, Simoneau-Robin I, Taskinen MR.

J Clin Endocrinol Metab. 2016 Apr;101(4):1398-406. doi: 10.1210/jc.2015-3740. Epub 2016 Feb 2.

PMID:
26835543
17.

Biomarkers and prediction of myocardial triglyceride content in non-diabetic men.

Granér M, Gustavsson S, Nyman K, Siren R, Pentikäinen MO, Lundbom J, Hakkarainen A, Lauerma K, Lundbom N, Borén J, Nieminen MS, Taskinen MR.

Nutr Metab Cardiovasc Dis. 2016 Feb;26(2):134-40. doi: 10.1016/j.numecd.2015.11.002. Epub 2015 Dec 12.

PMID:
26803593
18.

Weight Loss Is Associated With Increased NAD(+)/SIRT1 Expression But Reduced PARP Activity in White Adipose Tissue.

Rappou E, Jukarainen S, Rinnankoski-Tuikka R, Kaye S, Heinonen S, Hakkarainen A, Lundbom J, Lundbom N, Saunavaara V, Rissanen A, Virtanen KA, Pirinen E, Pietiläinen KH.

J Clin Endocrinol Metab. 2016 Mar;101(3):1263-73. doi: 10.1210/jc.2015-3054. Epub 2016 Jan 13.

PMID:
26760174
19.

The importance of needle gauge for pain during injection of lidocaine.

Wågø KJ, Skarsvåg TI, Lundbom JS, Tangen LF, Ballo S, Hjelseng T, Finsen V.

J Plast Surg Hand Surg. 2016;50(2):115-8. doi: 10.3109/2000656X.2015.1111223. Epub 2015 Nov 23.

PMID:
26595751
20.

Obesity Is Associated With Low NAD(+)/SIRT Pathway Expression in Adipose Tissue of BMI-Discordant Monozygotic Twins.

Jukarainen S, Heinonen S, Rämö JT, Rinnankoski-Tuikka R, Rappou E, Tummers M, Muniandy M, Hakkarainen A, Lundbom J, Lundbom N, Kaprio J, Rissanen A, Pirinen E, Pietiläinen KH.

J Clin Endocrinol Metab. 2016 Jan;101(1):275-83. doi: 10.1210/jc.2015-3095. Epub 2015 Nov 17.

PMID:
26574954
21.

DNA methylation and gene expression patterns in adipose tissue differ significantly within young adult monozygotic BMI-discordant twin pairs.

Pietiläinen KH, Ismail K, Järvinen E, Heinonen S, Tummers M, Bollepalli S, Lyle R, Muniandy M, Moilanen E, Hakkarainen A, Lundbom J, Lundbom N, Rissanen A, Kaprio J, Ollikainen M.

Int J Obes (Lond). 2016 Apr;40(4):654-61. doi: 10.1038/ijo.2015.221. Epub 2015 Oct 26.

PMID:
26499446
22.

The influence of injection speed on pain during injection of local anaesthetic.

Tangen LF, Lundbom JS, Skarsvåg TI, Wågø KJ, Ballo S, Hjelseng T, Finsen V.

J Plast Surg Hand Surg. 2016;50(1):7-9. doi: 10.3109/2000656X.2015.1058269. Epub 2015 Sep 28.

PMID:
26414074
23.

Pancreatic triacylglycerol distribution in type 2 diabetes. Reply to Hollingsworth K. G., Al Mrabeh A., Steven S. et al [letter].

Begovatz P, Bierwagen A, Lundbom J, Roden M.

Diabetologia. 2015 Nov;58(11):2679-81. doi: 10.1007/s00125-015-3770-x. Epub 2015 Sep 23. No abstract available.

PMID:
26399402
24.

Bone marrow fat unsaturation in young adults is not affected by present or childhood obesity, but increases with age: A pilot study.

Huovinen V, Viljakainen H, Hakkarainen A, Saukkonen T, Toiviainen-Salo S, Lundbom N, Lundbom J, Mäkitie O.

Metabolism. 2015 Nov;64(11):1574-81. doi: 10.1016/j.metabol.2015.08.014. Epub 2015 Aug 28.

PMID:
26388537
25.

Characterization of the peak at 2.06 ppm in (31) P magnetic resonance spectroscopy of human liver: phosphoenolpyruvate or phosphatidylcholine?

Bierwagen A, Begovatz P, Nowotny P, Markgraf D, Nowotny B, Koliaki C, Giani G, Klüppelholz B, Lundbom J, Roden M.

NMR Biomed. 2015 Jul;28(7):898-905. doi: 10.1002/nbm.3323. Epub 2015 May 25.

PMID:
26010913
26.

Does adjusting the pH of lidocaine reduce pain during injection?

Skarsvåg TI, Wågø KJ, Tangen LF, Lundbom JS, Hjelseng T, Ballo S, Finsen V.

J Plast Surg Hand Surg. 2015 May 19:1-3. [Epub ahead of print]

PMID:
25991379
27.

Impaired Mitochondrial Biogenesis in Adipose Tissue in Acquired Obesity.

Heinonen S, Buzkova J, Muniandy M, Kaksonen R, Ollikainen M, Ismail K, Hakkarainen A, Lundbom J, Lundbom N, Vuolteenaho K, Moilanen E, Kaprio J, Rissanen A, Suomalainen A, Pietiläinen KH.

Diabetes. 2015 Sep;64(9):3135-45. doi: 10.2337/db14-1937. Epub 2015 May 13.

28.

Genome-wide blood DNA methylation alterations at regulatory elements and heterochromatic regions in monozygotic twins discordant for obesity and liver fat.

Ollikainen M, Ismail K, Gervin K, Kyllönen A, Hakkarainen A, Lundbom J, Järvinen EA, Harris JR, Lundbom N, Rissanen A, Lyle R, Pietiläinen KH, Kaprio J.

Clin Epigenetics. 2015 Apr 2;7:39. doi: 10.1186/s13148-015-0073-5. eCollection 2015.

29.

Ectopic fat depots and left ventricular function in nondiabetic men with nonalcoholic fatty liver disease.

Granér M, Nyman K, Siren R, Pentikäinen MO, Lundbom J, Hakkarainen A, Lauerma K, Lundbom N, Nieminen MS, Taskinen MR.

Circ Cardiovasc Imaging. 2014 Dec 30;8(1). pii: e001979. doi: 10.1161/CIRCIMAGING.114.001979. Print 2015 Jan.

30.

Measuring short-term liver metabolism non-invasively: postprandial and post-exercise ¹H and ³¹P MR spectroscopy.

Hakkarainen A, Lundbom J, Tuominen EK, Taskinen MR, Pietiläinen KH, Lundbom N.

MAGMA. 2015 Feb;28(1):57-66. doi: 10.1007/s10334-014-0450-7. Epub 2014 Jun 4.

PMID:
24895090
31.

Metabolome and fecal microbiota in monozygotic twin pairs discordant for weight: a Big Mac challenge.

Bondia-Pons I, Maukonen J, Mattila I, Rissanen A, Saarela M, Kaprio J, Hakkarainen A, Lundbom J, Lundbom N, Hyötyläinen T, Pietiläinen KH, Orešič M.

FASEB J. 2014 Sep;28(9):4169-79. doi: 10.1096/fj.14-250167. Epub 2014 May 20.

32.

Cardiac steatosis in patients with dilated cardiomyopathy.

Granér M, Pentikäinen MO, Nyman K, Siren R, Lundbom J, Hakkarainen A, Lauerma K, Lundbom N, Nieminen MS, Petzold M, Taskinen MR.

Heart. 2014 Jul;100(14):1107-12. doi: 10.1136/heartjnl-2013-304961. Epub 2014 Apr 24.

PMID:
24763492
33.

Adipocyte morphology and implications for metabolic derangements in acquired obesity.

Heinonen S, Saarinen L, Naukkarinen J, Rodríguez A, Frühbeck G, Hakkarainen A, Lundbom J, Lundbom N, Vuolteenaho K, Moilanen E, Arner P, Hautaniemi S, Suomalainen A, Kaprio J, Rissanen A, Pietiläinen KH.

Int J Obes (Lond). 2014 Nov;38(11):1423-31. doi: 10.1038/ijo.2014.31. Epub 2014 Feb 19.

PMID:
24549139
34.

Electrocardiographic changes associated with insulin resistance.

Granér M, Pentikäinen MO, Siren R, Nyman K, Lundbom J, Hakkarainen A, Lauerma K, Lundbom N, Nieminen MS, Taskinen MR.

Nutr Metab Cardiovasc Dis. 2014 Mar;24(3):315-20. doi: 10.1016/j.numecd.2013.09.013. Epub 2013 Nov 1.

PMID:
24462049
35.

Cardiac steatosis and left ventricular function in men with metabolic syndrome.

Nyman K, Granér M, Pentikäinen MO, Lundbom J, Hakkarainen A, Sirén R, Nieminen MS, Taskinen MR, Lundbom N, Lauerma K.

J Cardiovasc Magn Reson. 2013 Nov 14;15:103. doi: 10.1186/1532-429X-15-103.

36.

Characterising metabolically healthy obesity in weight-discordant monozygotic twins.

Naukkarinen J, Heinonen S, Hakkarainen A, Lundbom J, Vuolteenaho K, Saarinen L, Hautaniemi S, Rodriguez A, Frühbeck G, Pajunen P, Hyötyläinen T, Orešič M, Moilanen E, Suomalainen A, Lundbom N, Kaprio J, Rissanen A, Pietiläinen KH.

Diabetologia. 2014 Jan;57(1):167-76. doi: 10.1007/s00125-013-3066-y. Epub 2013 Oct 8.

PMID:
24100782
37.

GLP-1 responses are heritable and blunted in acquired obesity with high liver fat and insulin resistance.

Matikainen N, Bogl LH, Hakkarainen A, Lundbom J, Lundbom N, Kaprio J, Rissanen A, Holst JJ, Pietiläinen KH.

Diabetes Care. 2014;37(1):242-51. doi: 10.2337/dc13-1283. Epub 2013 Aug 29.

PMID:
23990519
38.

Acquired liver fat is a key determinant of serum lipid alterations in healthy monozygotic twins.

Kaye SM, Maranghi M, Bogl LH, Kaprio J, Hakkarainen A, Lundbom J, Lundbom N, Rissanen A, Taskinen MR, Pietiläinen KH.

Obesity (Silver Spring). 2013 Sep;21(9):1815-22. doi: 10.1002/oby.20228. Epub 2013 May 21.

39.

Cardiac steatosis associates with visceral obesity in nondiabetic obese men.

Granér M, Siren R, Nyman K, Lundbom J, Hakkarainen A, Pentikäinen MO, Lauerma K, Lundbom N, Adiels M, Nieminen MS, Taskinen MR.

J Clin Endocrinol Metab. 2013 Mar;98(3):1189-97. doi: 10.1210/jc.2012-3190. Epub 2013 Feb 15.

PMID:
23418318
40.

Effect of short-term carbohydrate overfeeding and long-term weight loss on liver fat in overweight humans.

Sevastianova K, Santos A, Kotronen A, Hakkarainen A, Makkonen J, Silander K, Peltonen M, Romeo S, Lundbom J, Lundbom N, Olkkonen VM, Gylling H, Fielding BA, Rissanen A, Yki-Järvinen H.

Am J Clin Nutr. 2012 Oct;96(4):727-34. Epub 2012 Sep 5.

PMID:
22952180
41.

CB(1) blockade-induced weight loss over 48 weeks decreases liver fat in proportion to weight loss in humans.

Bergholm R, Sevastianova K, Santos A, Kotronen A, Urjansson M, Hakkarainen A, Lundbom J, Tiikkainen M, Rissanen A, Lundbom N, Yki-Järvinen H.

Int J Obes (Lond). 2013 May;37(5):699-703. doi: 10.1038/ijo.2012.116. Epub 2012 Jul 17.

PMID:
22828945
42.

Deep subcutaneous adipose tissue is more saturated than superficial subcutaneous adipose tissue.

Lundbom J, Hakkarainen A, Lundbom N, Taskinen MR.

Int J Obes (Lond). 2013 Apr;37(4):620-2. doi: 10.1038/ijo.2012.72. Epub 2012 May 29.

PMID:
22641063
43.

Body electrical loss analysis (BELA) in the assessment of visceral fat: a demonstration.

Blomqvist KH, Lundbom J, Lundbom N, Sepponen RE.

Biomed Eng Online. 2011 Nov 10;10:98. doi: 10.1186/1475-925X-10-98.

44.

Dual metabolic defects are required to produce hypertriglyceridemia in obese subjects.

Taskinen MR, Adiels M, Westerbacka J, Söderlund S, Kahri J, Lundbom N, Lundbom J, Hakkarainen A, Olofsson SO, Orho-Melander M, Borén J.

Arterioscler Thromb Vasc Biol. 2011 Sep;31(9):2144-50. doi: 10.1161/ATVBAHA.111.224808. Epub 2011 Jul 21.

45.

Genetic variation in PNPLA3 (adiponutrin) confers sensitivity to weight loss-induced decrease in liver fat in humans.

Sevastianova K, Kotronen A, Gastaldelli A, Perttilä J, Hakkarainen A, Lundbom J, Suojanen L, Orho-Melander M, Lundbom N, Ferrannini E, Rissanen A, Olkkonen VM, Yki-Järvinen H.

Am J Clin Nutr. 2011 Jul;94(1):104-11. doi: 10.3945/ajcn.111.012369. Epub 2011 Apr 27.

PMID:
21525193
46.

Long-TE 1H MRS suggests that liver fat is more saturated than subcutaneous and visceral fat.

Lundbom J, Hakkarainen A, Söderlund S, Westerbacka J, Lundbom N, Taskinen MR.

NMR Biomed. 2011 Apr;24(3):238-45. doi: 10.1002/nbm.1580. Epub 2010 Sep 6.

PMID:
20821410
47.

Nonalcoholic fatty liver disease: detection of elevated nicotinamide adenine dinucleotide phosphate with in vivo 3.0-T 31P MR spectroscopy with proton decoupling.

Sevastianova K, Hakkarainen A, Kotronen A, Cornér A, Arkkila P, Arola J, Westerbacka J, Bergholm R, Lundbom J, Lundbom N, Yki-Järvinen H.

Radiology. 2010 Aug;256(2):466-73. doi: 10.1148/radiol.10091351.

PMID:
20656836
48.

Characterizing human adipose tissue lipids by long echo time 1H-MRS in vivo at 1.5 Tesla: validation by gas chromatography.

Lundbom J, Hakkarainen A, Fielding B, Söderlund S, Westerbacka J, Taskinen MR, Lundbom N.

NMR Biomed. 2010 Jun;23(5):466-72. doi: 10.1002/nbm.1483.

PMID:
20099371
49.

PRESS echo time behavior of triglyceride resonances at 1.5T: detecting omega-3 fatty acids in adipose tissue in vivo.

Lundbom J, Heikkinen S, Fielding B, Hakkarainen A, Taskinen MR, Lundbom N.

J Magn Reson. 2009 Nov;201(1):39-47. doi: 10.1016/j.jmr.2009.07.026. Epub 2009 Aug 3.

PMID:
19699126
50.

Recovery following treatment of descending thoracic aortic disease. A comparison between endovascular repair and open surgery.

Aasland J, Lundbom J, Eide TO, Odegård A, Aadahl P, Romundstad PR, Myhre HO.

Int Angiol. 2005 Sep;24(3):231-7.

PMID:
16158031

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