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Items: 1 to 50 of 279

1.

Early-Life Stress Does Not Aggravate Spatial Memory or the Process of Hippocampal Neurogenesis in Adult and Middle-Aged APP/PS1 Mice.

Hoeijmakers L, Amelianchik A, Verhaag F, Kotah J, Lucassen PJ, Korosi A.

Front Aging Neurosci. 2018 Mar 7;10:61. doi: 10.3389/fnagi.2018.00061. eCollection 2018.

2.

Targeting glucocorticoid receptors prevents the effects of early life stress on amyloid pathology and cognitive performance in APP/PS1 mice.

Lesuis SL, Weggen S, Baches S, Lucassen PJ, Krugers HJ.

Transl Psychiatry. 2018 Mar 1;8(1):53. doi: 10.1038/s41398-018-0101-2.

3.

Development of a health assessment instrument for people with intellectual disabilities: a Delphi study.

Bakker-van Gijssel EJ, Lucassen PLBJ, Olde Hartman TC, Assendelft WJJ, van Schrojenstein Lantman-de Valk HMJ.

Fam Pract. 2018 Feb 17. doi: 10.1093/fampra/cmy004. [Epub ahead of print]

PMID:
29471438
4.

Stress and Corticosteroids Aggravate Morphological Changes in the Dentate Gyrus after Early-Life Experimental Febrile Seizures in Mice.

van Campen JS, Hessel EVS, Bohmbach K, Rizzi G, Lucassen PJ, Lakshmi Turimella S, Umeoka EHL, Meerhoff GF, Braun KPJ, de Graan PNE, Joëls M.

Front Endocrinol (Lausanne). 2018 Jan 26;9:3. doi: 10.3389/fendo.2018.00003. eCollection 2018.

5.

Facilitators and barriers in the diagnostic process of vulvovaginal complaints (vulvodynia) in general practice: a qualitative study.

Leusink P, Teunissen D, Lucassen PL, Laan ET, Lagro-Janssen AL.

Eur J Gen Pract. 2018 Dec;24(1):92-98. doi: 10.1080/13814788.2017.1420774.

6.

A cross-sectional examination of psychological distress, positive mental health and their predictors in medical students in their clinical clerkships.

van Dijk I, Lucassen PLBJ, van Weel C, Speckens AEM.

BMC Med Educ. 2017 Nov 17;17(1):219. doi: 10.1186/s12909-017-1035-8.

7.

The age-related slow increase in amyloid pathology in APP.V717I mice activates microglia, but does not alter hippocampal neurogenesis.

Hoeijmakers L, Meerhoff GF, de Vries JW, Ruigrok SR, van Dam AM, van Leuven F, Korosi A, Lucassen PJ.

Neurobiol Aging. 2018 Jan;61:112-123. doi: 10.1016/j.neurobiolaging.2017.09.013. Epub 2017 Sep 22.

PMID:
29059594
8.

Pain characteristics of older persons with medically unexplained symptoms, older persons with medically explained symptoms and older persons with depression.

Hanssen DJC, Lucassen PLBJ, Naarding P, de Waal MWM, Oude Voshaar RC.

Aging Ment Health. 2017 Oct 11:1-8. doi: 10.1080/13607863.2017.1387762. [Epub ahead of print]

PMID:
29019415
9.

Neuropsychiatric symptoms and psychotropic drug use in patients with dementia in general practices.

Borsje P, Lucassen PLBJ, Wetzels RB, Pot AM, Koopmans RTCM.

Fam Pract. 2018 Jan 16;35(1):22-28. doi: 10.1093/fampra/cmx061.

PMID:
28985387
10.

Ghrelin and hypothalamic NPY/AgRP expression in mice are affected by chronic early-life stress exposure in a sex-specific manner.

Yam KY, Ruigrok SR, Ziko I, De Luca SN, Lucassen PJ, Spencer SJ, Korosi A.

Psychoneuroendocrinology. 2017 Dec;86:73-77. doi: 10.1016/j.psyneuen.2017.09.006. Epub 2017 Sep 7.

PMID:
28917185
11.

Improving GP communication in consultations on medically unexplained symptoms: a qualitative interview study with patients in primary care.

Houwen J, Lucassen PL, Stappers HW, Assendelft WJ, van Dulmen S, Olde Hartman TC.

Br J Gen Pract. 2017 Oct;67(663):e716-e723. doi: 10.3399/bjgp17X692537. Epub 2017 Aug 28.

PMID:
28847774
12.

Age-dependent, lasting effects of methylphenidate on the GABAergic system of ADHD patients.

Solleveld MM, Schrantee A, Puts NAJ, Reneman L, Lucassen PJ.

Neuroimage Clin. 2017 Jun 2;15:812-818. doi: 10.1016/j.nicl.2017.06.003. eCollection 2017.

13.

[Approaching psychological problems like a general practitioner].

Lucassen PLBJ, Postma S, Olde Hartman TC, van Ravesteijn H, Linssen MJ, Wolf J, Gerritsen DL.

Ned Tijdschr Geneeskd. 2017;161(0):D1474. Dutch.

PMID:
28659209
14.

Behavioural activation by mental health nurses for late-life depression in primary care: a randomized controlled trial.

Janssen N, Huibers MJH, Lucassen P, Voshaar RO, van Marwijk H, Bosmans J, Pijnappels M, Spijker J, Hendriks GJ.

BMC Psychiatry. 2017 Jun 26;17(1):230. doi: 10.1186/s12888-017-1388-x.

15.

Chronic early life stress induced by limited bedding and nesting (LBN) material in rodents: critical considerations of methodology, outcomes and translational potential.

Walker CD, Bath KG, Joels M, Korosi A, Larauche M, Lucassen PJ, Morris MJ, Raineki C, Roth TL, Sullivan RM, Taché Y, Baram TZ.

Stress. 2017 Sep;20(5):421-448. doi: 10.1080/10253890.2017.1343296. Epub 2017 Jul 12.

PMID:
28617197
16.

Early postnatal handling reduces hippocampal amyloid plaque formation and enhances cognitive performance in APPswe/PS1dE9 mice at middle age.

Lesuis SL, van Hoek BACE, Lucassen PJ, Krugers HJ.

Neurobiol Learn Mem. 2017 Oct;144:27-35. doi: 10.1016/j.nlm.2017.05.016. Epub 2017 Jun 1.

PMID:
28579367
17.

Early-life stress diminishes the increase in neurogenesis after exercise in adult female mice.

Abbink MR, Naninck EFG, Lucassen PJ, Korosi A.

Hippocampus. 2017 Aug;27(8):839-844. doi: 10.1002/hipo.22745. Epub 2017 Jun 6.

PMID:
28558121
18.

Health assessment instruments for people with intellectual disabilities-A systematic review.

Bakker-van Gijssel EJ, Lucassen PLBJ, Olde Hartman TC, van Son L, Assendelft WJJ, van Schrojenstein Lantman-de Valk HMJ.

Res Dev Disabil. 2017 May;64:12-24. doi: 10.1016/j.ridd.2017.03.002. Epub 2017 Mar 16. Review.

PMID:
28327382
19.

Transcription factor oscillations in neural stem cells: Implications for accurate control of gene expression.

Bielefeld P, Schouten M, Lucassen PJ, Fitzsimons CP.

Neurogenesis (Austin). 2017 Feb 10;4(1):e1262934. doi: 10.1080/23262133.2016.1262934. eCollection 2017. Review.

20.

Repeated dexamphetamine treatment alters the dopaminergic system and increases the phMRI response to methylphenidate.

Schrantee A, Tremoleda JL, Wylezinska-Arridge M, Bouet V, Hesseling P, Meerhoff GF, de Bruin KM, Koeleman J, Freret T, Boulouard M, Desfosses E, Galineau L, Gozzi A, Dauphin F, Gsell W, Booij J, Lucassen PJ, Reneman L.

PLoS One. 2017 Feb 27;12(2):e0172776. doi: 10.1371/journal.pone.0172776. eCollection 2017.

21.

Early life adversity: Lasting consequences for emotional learning.

Krugers HJ, Arp JM, Xiong H, Kanatsou S, Lesuis SL, Korosi A, Joels M, Lucassen PJ.

Neurobiol Stress. 2016 Nov 27;6:14-21. doi: 10.1016/j.ynstr.2016.11.005. eCollection 2017 Feb. Review.

22.

"Medically unexplained" symptoms and symptom disorders in primary care: prognosis-based recognition and classification.

Rosendal M, Olde Hartman TC, Aamland A, van der Horst H, Lucassen P, Budtz-Lilly A, Burton C.

BMC Fam Pract. 2017 Feb 7;18(1):18. doi: 10.1186/s12875-017-0592-6.

23.

Negotiating explanations: doctor-patient communication with patients with medically unexplained symptoms-a qualitative analysis.

den Boeft M, Huisman D, Morton L, Lucassen P, van der Wouden JC, Westerman MJ, van der Horst HE, Burton CD.

Fam Pract. 2017 Feb;34(1):107-113. doi: 10.1093/fampra/cmw113. Epub 2016 Nov 20.

PMID:
28122926
24.

Medically unexplained symptoms: the person, the symptoms and the dialogue.

Houwen J, Lucassen PLBJ, Stappers HW, Assendelft PJJ, van Dulmen S, Olde Hartman TC.

Fam Pract. 2017 Apr 1;34(2):245-251. doi: 10.1093/fampra/cmw132.

PMID:
28122842
25.

Effects of Mindfulness-Based Stress Reduction on the Mental Health of Clinical Clerkship Students: A Cluster-Randomized Controlled Trial.

van Dijk I, Lucassen PLBJ, Akkermans RP, van Engelen BGM, van Weel C, Speckens AEM.

Acad Med. 2017 Jul;92(7):1012-1021. doi: 10.1097/ACM.0000000000001546.

PMID:
28121650
26.

Exposure to chronic early-life stress lastingly alters the adipose tissue, the leptin system and changes the vulnerability to western-style diet later in life in mice.

Yam KY, Naninck EFG, Abbink MR, la Fleur SE, Schipper L, van den Beukel JC, Grefhorst A, Oosting A, van der Beek EM, Lucassen PJ, Korosi A.

Psychoneuroendocrinology. 2017 Mar;77:186-195. doi: 10.1016/j.psyneuen.2016.12.012. Epub 2016 Dec 23.

PMID:
28088658
27.

Early-life stress lastingly alters the neuroinflammatory response to amyloid pathology in an Alzheimer's disease mouse model.

Hoeijmakers L, Ruigrok SR, Amelianchik A, Ivan D, van Dam AM, Lucassen PJ, Korosi A.

Brain Behav Immun. 2017 Jul;63:160-175. doi: 10.1016/j.bbi.2016.12.023. Epub 2016 Dec 25.

PMID:
28027926
28.

GPs' opinions of health assessment instruments for people with intellectual disabilities: a qualitative study.

Bakker-van Gijssel EJ, Olde Hartman TC, Lucassen PL, van den Driessen Mareeuw F, Dees MK, Assendelft WJ, van Schrojenstein Lantman-de Valk HM.

Br J Gen Pract. 2017 Jan;67(654):e41-e48. doi: 10.3399/bjgp16X688585. Epub 2016 Dec 19.

29.

Context as a drug: some consequences of placebo research for primary care.

Lucassen P, Olesen F.

Scand J Prim Health Care. 2016 Dec;34(4):428-433. Epub 2016 Nov 20. Review.

30.

Why patients self-refer to the Emergency Department: A qualitative interview study.

Kraaijvanger N, Rijpsma D, Willink L, Lucassen P, van Leeuwen H, Edwards M.

J Eval Clin Pract. 2017 Jun;23(3):593-598. doi: 10.1111/jep.12680. Epub 2016 Dec 15.

PMID:
27976472
31.

Reliability and validity of the Dutch version of the Consultation and Relational Empathy Measure in primary care.

van Dijk I, Scholten Meilink Lenferink N, Lucassen PL, Mercer SW, van Weel C, Olde Hartman TC, Speckens AE.

Fam Pract. 2017 Feb;34(1):119-124. doi: 10.1093/fampra/cmw116. Epub 2016 Dec 5.

PMID:
27920117
32.

The Indispensable Roles of Microglia and Astrocytes during Brain Development.

Reemst K, Noctor SC, Lucassen PJ, Hol EM.

Front Hum Neurosci. 2016 Nov 8;10:566. eCollection 2016. Review.

33.

Positive and negative early life experiences differentially modulate long term survival and amyloid protein levels in a mouse model of Alzheimer's disease.

Lesuis SL, Maurin H, Borghgraef P, Lucassen PJ, Van Leuven F, Krugers HJ.

Oncotarget. 2016 Jun 28;7(26):39118-39135. doi: 10.18632/oncotarget.9776.

34.

Early micronutrient supplementation protects against early stress-induced cognitive impairments.

Naninck EF, Oosterink JE, Yam KY, de Vries LP, Schierbeek H, van Goudoever JB, Verkaik-Schakel RN, Plantinga JA, Plosch T, Lucassen PJ, Korosi A.

FASEB J. 2017 Feb;31(2):505-518. doi: 10.1096/fj.201600834R. Epub 2016 Oct 21.

PMID:
27770020
35.

Health-Related Quality of Life in Older Persons with Medically Unexplained Symptoms.

Hanssen DJC, Lucassen PLBJ, Hilderink PH, Naarding P, Voshaar RCO.

Am J Geriatr Psychiatry. 2016 Nov;24(11):1117-1127. doi: 10.1016/j.jagp.2016.07.013. Epub 2016 Jul 20.

PMID:
27618643
36.

Big Five personality traits and medically unexplained symptoms in later life.

van Dijk SD, Hanssen D, Naarding P, Lucassen P, Comijs H, Oude Voshaar R.

Eur Psychiatry. 2016 Oct;38:23-30. doi: 10.1016/j.eurpsy.2016.05.002. Epub 2016 Sep 7.

PMID:
27611331
37.

Microglial Priming and Alzheimer's Disease: A Possible Role for (Early) Immune Challenges and Epigenetics?

Hoeijmakers L, Heinen Y, van Dam AM, Lucassen PJ, Korosi A.

Front Hum Neurosci. 2016 Aug 9;10:398. doi: 10.3389/fnhum.2016.00398. eCollection 2016. Review.

38.

Social characteristics and care needs of older persons with medically unexplained symptoms: a case-control study.

Hanssen DJ, Oude Voshaar RC, Naarding P, Rabeling-Keus IM, Olde Hartman TC, Lucassen PL.

Fam Pract. 2016 Dec;33(6):617-625. Epub 2016 Aug 18.

PMID:
27538425
39.

Illness cognitions in later life: Development and validation of the Extended Illness Cognition Questionnaire (ICQ-Plus).

van Driel D, Hanssen D, Hilderink P, Naarding P, Lucassen P, Rosmalen J, Oude Voshaar R.

Psychol Assess. 2016 Sep;28(9):1119-27. doi: 10.1037/pas0000303.

PMID:
27537006
40.

[Depression prevention in primary care is not worthwhile].

Olde Hartman TC, Lucassen PL.

Ned Tijdschr Geneeskd. 2016;160(0):D639. Review. Dutch.

PMID:
27531250
41.

Multi-omics profile of the mouse dentate gyrus after kainic acid-induced status epilepticus.

Schouten M, Bielefeld P, Fratantoni SA, Hubens CJ, Piersma SR, Pham TV, Voskuyl RA, Lucassen PJ, Jimenez CR, Fitzsimons CP.

Sci Data. 2016 Aug 16;3:160068. doi: 10.1038/sdata.2016.68.

42.

Aerobic Exercise as a Tool to Improve Hippocampal Plasticity and Function in Humans: Practical Implications for Mental Health Treatment.

Kandola A, Hendrikse J, Lucassen PJ, Yücel M.

Front Hum Neurosci. 2016 Jul 29;10:373. doi: 10.3389/fnhum.2016.00373. eCollection 2016. Review.

43.

Age-Dependent Effects of Methylphenidate on the Human Dopaminergic System in Young vs Adult Patients With Attention-Deficit/Hyperactivity Disorder: A Randomized Clinical Trial.

Schrantee A, Tamminga HG, Bouziane C, Bottelier MA, Bron EE, Mutsaerts HJ, Zwinderman AH, Groote IR, Rombouts SA, Lindauer RJ, Klein S, Niessen WJ, Opmeer BC, Boer F, Lucassen PJ, Andersen SL, Geurts HM, Reneman L.

JAMA Psychiatry. 2016 Sep 1;73(9):955-62. doi: 10.1001/jamapsychiatry.2016.1572.

44.

Prefrontal changes in the glutamate-glutamine cycle and neuronal/glial glutamate transporters in depression with and without suicide.

Zhao J, Verwer RW, van Wamelen DJ, Qi XR, Gao SF, Lucassen PJ, Swaab DF.

J Psychiatr Res. 2016 Nov;82:8-15. doi: 10.1016/j.jpsychires.2016.06.017. Epub 2016 Jun 29.

PMID:
27450072
45.

GPs' experiences with enhanced collaboration between psychiatry and general practice for children with ADHD.

Hassink-Franke LJ, Janssen MM, Oehlen G, van Deurzen PA, Buitelaar JK, Wensing M, Lucassen PL.

Eur J Gen Pract. 2016 Sep;22(3):196-202. doi: 10.1080/13814788.2016.1177506. Epub 2016 Jun 3.

PMID:
27261089
46.

How do Dutch GPs address work-related problems? A focus group study.

de Kock CA, Lucassen PL, Spinnewijn L, Knottnerus JA, Buijs PC, Steenbeek R, Lagro-Janssen AL.

Eur J Gen Pract. 2016 Sep;22(3):169-75. doi: 10.1080/13814788.2016.1177507. Epub 2016 Jun 1.

PMID:
27248862
47.

Circadian and ultradian glucocorticoid rhythmicity: Implications for the effects of glucocorticoids on neural stem cells and adult hippocampal neurogenesis.

Fitzsimons CP, Herbert J, Schouten M, Meijer OC, Lucassen PJ, Lightman S.

Front Neuroendocrinol. 2016 Apr;41:44-58. doi: 10.1016/j.yfrne.2016.05.001. Epub 2016 May 24. Review.

PMID:
27234350
48.

Recognition of patients with medically unexplained physical symptoms by family physicians: results of a focus group study.

den Boeft M, Huisman D, van der Wouden JC, Numans ME, van der Horst HE, Lucassen PL, Olde Hartman TC.

BMC Fam Pract. 2016 May 12;17:55. doi: 10.1186/s12875-016-0451-x.

49.

'Life is still worth living': a pilot exploration of self-reported resources of palliative care patients.

Warmenhoven F, Lucassen P, Vermandere M, Aertgeerts B, van Weel C, Vissers K, Prins J.

BMC Fam Pract. 2016 May 10;17:52. doi: 10.1186/s12875-016-0450-y.

50.

Brief multimodal psychosomatic therapy in patients with medically unexplained symptoms: feasibility and treatment effects.

Wortman MS, Lucassen PL, van Ravesteijn HJ, Bor H, Assendelft PJ, Lucas C, Olde Hartman TC.

Fam Pract. 2016 Aug;33(4):346-53. doi: 10.1093/fampra/cmw023. Epub 2016 Apr 13.

PMID:
27075027

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