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Metastatic Breast Cancer Collateral Damage Project (MBCCD): Scale development and preliminary results of the Survey of Health, Impact, Needs, and Experiences (SHINE).

Williamson TJ, Love SM, Clague DeHart JN, Jorge-Miller A, Eshraghi L, Cooper Ortner H, Stanton AL.

Breast Cancer Res Treat. 2018 May 16. doi: 10.1007/s10549-018-4823-x. [Epub ahead of print]


Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology.

Horsburgh K, Wardlaw JM, van Agtmael T, Allan SM, Ashford MLJ, Bath PM, Brown R, Berwick J, Cader MZ, Carare RO, Davis JB, Duncombe J, Farr TD, Fowler JH, Goense J, Granata A, Hall CN, Hainsworth AH, Harvey A, Hawkes CA, Joutel A, Kalaria RN, Kehoe PG, Lawrence CB, Lockhart A, Love S, Macleod MR, Macrae IM, Markus HS, McCabe C, McColl BW, Meakin PJ, Miller A, Nedergaard M, O'Sullivan M, Quinn TJ, Rajani R, Saksida LM, Smith C, Smith KJ, Touyz RM, Trueman RC, Wang T, Williams A, Williams SCR, Work LM.

Clin Sci (Lond). 2018 Apr 30;132(8):851-868. doi: 10.1042/CS20171620. Print 2018 Apr 30. Review.


The effect of size and polymer architecture of doxorubicin-poly(ethylene) glycol conjugate nanocarriers on breast duct retention, potency and toxicity.

Gu Z, Gao D, Al-Zubaydi F, Li S, Singh Y, Rivera K, Holloway J, Szekely Z, Love S, Sinko PJ.

Eur J Pharm Sci. 2018 Apr 24;121:118-125. doi: 10.1016/j.ejps.2018.04.033. [Epub ahead of print]


A diagnostic cohort study on the accuracy of 18-fluorodeoxyglucose (18FDG) positron emission tomography (PET)-CT for evaluation of malignancy in anterior mediastinal lesions: the DECiMaL study.

Proli C, De Sousa P, Jordan S, Anikin V, Devaraj A, Love SM, Shackcloth M, Kostoulas N, Papagiannopoulos K, Haqzad Y, Loubani M, Sellitri F, Granato F, Bush A, Marchbank A, Iyer S, Scarci M, Lim E; UK Thoracic Surgery Research Collaborative.

BMJ Open. 2018 Feb 6;8(2):e019471. doi: 10.1136/bmjopen-2017-019471.


Long-term administration of tacrolimus and everolimus prevents high cholesterol-high fructose-induced steatosis in C57BL/6J mice by inhibiting de-novo lipogenesis.

Love S, Mudasir MA, Bhardwaj SC, Singh G, Tasduq SA.

Oncotarget. 2017 Feb 8;8(69):113403-113417. doi: 10.18632/oncotarget.15194. eCollection 2017 Dec 26.


Challenges in implementing model-based phase I designs in a grant-funded clinical trials unit.

Frangou E, Holmes J, Love S, McGregor N, Hawkins M.

Trials. 2017 Dec 28;18(1):620. doi: 10.1186/s13063-017-2389-2.


Low pO2 Contributes to Potential Error in Oxygen Saturation Calculations Using a Point-of-Care Assay.

Gunsolus IL, Love SA, Kohl LP, Schmidt M, Apple FS.

Am J Clin Pathol. 2017 Dec 20;149(1):82-86. doi: 10.1093/ajcp/aqx152.


VEGFR1 and VEGFR2 in Alzheimer's Disease.

Harris R, Miners JS, Allen S, Love S.

J Alzheimers Dis. 2018;61(2):741-752. doi: 10.3233/JAD-170745.


A case of chronic asymptomatic central pontine myelinolysis with histological evidence of remyelination.

Haynes HR, Gallagher PJ, Cordaro A, Likeman M, Love S.

Forensic Sci Med Pathol. 2018 Mar;14(1):106-108. doi: 10.1007/s12024-017-9933-y. Epub 2017 Nov 25.


Reply to letter by Trupp et al.

Apple FS, Saenger AK, Gunsolus IL, Love SA, Jaffe AS.

Clin Biochem. 2018 Feb;52:174. doi: 10.1016/j.clinbiochem.2017.11.012. Epub 2017 Nov 21. No abstract available.


Distribution of the branched-chain α-ketoacid dehydrogenase complex E1α subunit and glutamate dehydrogenase in the human brain and their role in neuro-metabolism.

Hull J, Usmari Moraes M, Brookes E, Love S, Conway ME.

Neurochem Int. 2018 Jan;112:49-58. doi: 10.1016/j.neuint.2017.10.014. Epub 2017 Nov 9.


Measuring informed consent capacity in an Alzheimer's disease clinical trial.

Guarino PD, Vertrees JE, Asthana S, Sano M, Llorente MD, Pallaki M, Love S, Schellenberg GD, Dysken MW.

Alzheimers Dement (N Y). 2016 Sep 20;2(4):258-266. doi: 10.1016/j.trci.2016.09.001. eCollection 2016 Nov.


Overexpression of Kinesin Superfamily Motor Proteins in Alzheimer's Disease.

Hares K, Miners JS, Cook AJ, Rice C, Scolding N, Love S, Wilkins A.

J Alzheimers Dis. 2017;60(4):1511-1524. doi: 10.3233/JAD-170094.


Progress toward standardized diagnosis of vascular cognitive impairment: Guidelines from the Vascular Impairment of Cognition Classification Consensus Study.

Skrobot OA, Black SE, Chen C, DeCarli C, Erkinjuntti T, Ford GA, Kalaria RN, O'Brien J, Pantoni L, Pasquier F, Roman GC, Wallin A, Sachdev P, Skoog I; VICCCS group, Ben-Shlomo Y, Passmore AP, Love S, Kehoe PG.

Alzheimers Dement. 2018 Mar;14(3):280-292. doi: 10.1016/j.jalz.2017.09.007. Epub 2017 Oct 19.


Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha.

Olmez I, Love S, Xiao A, Manigat L, Randolph P, McKenna BD, Neal BP, Boroda S, Li M, Brenneman B, Abounader R, Floyd D, Lee J, Nakano I, Godlewski J, Bronisz A, Sulman EP, Mayo M, Gioeli D, Weber M, Harris TE, Purow B.

Neuro Oncol. 2018 Jan 22;20(2):192-202. doi: 10.1093/neuonc/nox119.


Downregulated apoptosis and autophagy after anti-Aβ immunotherapy in Alzheimer's disease.

Paquet C, Nicoll JA, Love S, Mouton-Liger F, Holmes C, Hugon J, Boche D.

Brain Pathol. 2017 Oct 13. doi: 10.1111/bpa.12567. [Epub ahead of print]


Sex-specific 99th percentiles derived from the AACC Universal Sample Bank for the Roche Gen 5 cTnT assay: Comorbidities and statistical methods influence derivation of reference limits.

Gunsolus IL, Jaffe AS, Sexter A, Schulz K, Ler R, Lindgren B, Saenger AK, Love SA, Apple FS.

Clin Biochem. 2017 Dec;50(18):1073-1077. doi: 10.1016/j.clinbiochem.2017.09.009. Epub 2017 Sep 13.


Transcriptional profiling identifies differential expression of long non-coding RNAs in Jo-1 associated and inclusion body myositis.

Hamann PD, Roux BT, Heward JA, Love S, McHugh NJ, Jones SW, Lindsay MA.

Sci Rep. 2017 Aug 14;7(1):8024. doi: 10.1038/s41598-017-08603-9.


Cerebral Aβ40 and systemic hypertension.

Tayler HM, Palmer JC, Thomas TL, Kehoe PG, Paton JF, Love S.

J Cereb Blood Flow Metab. 2017 Jan 1:271678X17724930. doi: 10.1177/0271678X17724930. [Epub ahead of print]


First-line selective internal radiotherapy plus chemotherapy versus chemotherapy alone in patients with liver metastases from colorectal cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Global): a combined analysis of three multicentre, randomised, phase 3 trials.

Wasan HS, Gibbs P, Sharma NK, Taieb J, Heinemann V, Ricke J, Peeters M, Findlay M, Weaver A, Mills J, Wilson C, Adams R, Francis A, Moschandreas J, Virdee PS, Dutton P, Love S, Gebski V, Gray A; FOXFIRE trial investigators; SIRFLOX trial investigators; FOXFIRE-Global trial investigators, van Hazel G, Sharma RA.

Lancet Oncol. 2017 Sep;18(9):1159-1171. doi: 10.1016/S1470-2045(17)30457-6. Epub 2017 Aug 3.


Familiarity and Voice Representation: From Acoustic-Based Representation to Voice Averages.

Fontaine M, Love SA, Latinus M.

Front Psychol. 2017 Jul 14;8:1180. doi: 10.3389/fpsyg.2017.01180. eCollection 2017.


Type 1 and 2 Myocardial Infarction and Myocardial Injury: Clinical Transition to High-Sensitivity Cardiac Troponin I.

Sandoval Y, Smith SW, Sexter A, Thordsen SE, Bruen CA, Carlson MD, Dodd KW, Driver BE, Hu Y, Jacoby K, Johnson BK, Love SA, Moore JC, Schulz K, Scott NL, Apple FS.

Am J Med. 2017 Dec;130(12):1431-1439.e4. doi: 10.1016/j.amjmed.2017.05.049. Epub 2017 Jul 21.


Effect of APOE Genotype on Synaptic Proteins in Earlier Adult Life.

Sinclair LI, Love S.

J Alzheimers Dis. 2017;59(3):1123-1137. doi: 10.3233/JAD-170316.


Diagnostic Performance of High Sensitivity Compared with Contemporary Cardiac Troponin I for the Diagnosis of Acute Myocardial Infarction.

Sandoval Y, Smith SW, Thordsen SE, Bruen CA, Carlson MD, Dodd KW, Driver BE, Jacoby K, Johnson BK, Love SA, Moore JC, Sexter A, Schulz K, Scott NL, Nicholson J, Apple FS.

Clin Chem. 2017 Oct;63(10):1594-1604. doi: 10.1373/clinchem.2017.272930. Epub 2017 Jul 12.


Small vessel disease, neurovascular regulation and cognitive impairment: post-mortem studies reveal a complex relationship, still poorly understood.

Love S, Miners JS.

Clin Sci (Lond). 2017 Jun 30;131(14):1579-1589. doi: 10.1042/CS20170148. Print 2017 Jul 15. Review.


Embracing model-based designs for dose-finding trials.

Love SB, Brown S, Weir CJ, Harbron C, Yap C, Gaschler-Markefski B, Matcham J, Caffrey L, McKevitt C, Clive S, Craddock C, Spicer J, Cornelius V.

Br J Cancer. 2017 Jul 25;117(3):332-339. doi: 10.1038/bjc.2017.186. Epub 2017 Jun 29. Review.


What is the role of stereotactic ablative radiotherapy in the management of surgically resectable and operable stage I non-small cell lung cancer?

Love SM, Hardman G, Mashar R, Shah RD.

J Thorac Dis. 2017 May;9(5):E483-E486. doi: 10.21037/jtd.2017.03.57. No abstract available.


Multisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG).

Kovacs GG, Xie SX, Lee EB, Robinson JL, Caswell C, Irwin DJ, Toledo JB, Johnson VE, Smith DH, Alafuzoff I, Attems J, Bencze J, Bieniek KF, Bigio EH, Bodi I, Budka H, Dickson DW, Dugger BN, Duyckaerts C, Ferrer I, Forrest SL, Gelpi E, Gentleman SM, Giaccone G, Grinberg LT, Halliday GM, Hatanpaa KJ, Hof PR, Hofer M, Hortobágyi T, Ironside JW, King A, Kofler J, Kövari E, Kril JJ, Love S, Mackenzie IR, Mao Q, Matej R, McLean C, Munoz DG, Murray ME, Neltner J, Nelson PT, Ritchie D, Rodriguez RD, Rohan Z, Rozemuller A, Sakai K, Schultz C, Seilhean D, Smith V, Tacik P, Takahashi H, Takao M, Rudolf Thal D, Weis S, Wharton SB, White CL 3rd, Woulfe JM, Yamada M, Trojanowski JQ.

J Neuropathol Exp Neurol. 2017 Jul 1;76(7):605-619. doi: 10.1093/jnen/nlx041.


Trigeminal Nerve Root Demyelination Not Seen in Six Horses Diagnosed with Trigeminal-Mediated Headshaking.

Roberts VL, Fews D, McNamara JM, Love S.

Front Vet Sci. 2017 May 15;4:72. doi: 10.3389/fvets.2017.00072. eCollection 2017.


Left Brain Asymmetry of the Planum Temporale in a Nonhominid Primate: Redefining the Origin of Brain Specialization for Language.

Marie D, Roth M, Lacoste R, Nazarian B, Bertello A, Anton JL, Hopkins WD, Margiotoudi K, Love SA, Meguerditchian A.

Cereb Cortex. 2018 May 1;28(5):1808-1815. doi: 10.1093/cercor/bhx096.


Heroin-related Deaths from the Hennepin County Medical Examiner's Office from 2004 Through 2015.

Love SA, Lelinski J, Kloss J, Middleton O, Apple FS.

J Forensic Sci. 2018 Jan;63(1):191-194. doi: 10.1111/1556-4029.13511. Epub 2017 Apr 19.


Protocol for Combined Analysis of FOXFIRE, SIRFLOX, and FOXFIRE-Global Randomized Phase III Trials of Chemotherapy +/- Selective Internal Radiation Therapy as First-Line Treatment for Patients With Metastatic Colorectal Cancer.

Virdee PS, Moschandreas J, Gebski V, Love SB, Francis EA, Wasan HS, van Hazel G, Gibbs P, Sharma RA.

JMIR Res Protoc. 2017 Mar 28;6(3):e43. doi: 10.2196/resprot.7201.


Single High-Sensitivity Cardiac Troponin I to Rule Out Acute Myocardial Infarction.

Sandoval Y, Smith SW, Love SA, Sexter A, Schulz K, Apple FS.

Am J Med. 2017 Sep;130(9):1076-1083.e1. doi: 10.1016/j.amjmed.2017.02.032. Epub 2017 Mar 24.


Endothelin-converting enzymes degrade α-synuclein and are reduced in dementia with Lewy bodies.

Miners JS, Love S.

J Neurochem. 2017 Apr;141(2):275-286. doi: 10.1111/jnc.13974. Epub 2017 Mar 29.


Is it time for SABR to overtake surgery as the treatment of choice for stage I non-small cell lung cancer?

Love SM, Hardman G, Mashar R, Shah RD.

Ann Transl Med. 2016 Dec;4(24):535. doi: 10.21037/atm.2016.11.69. No abstract available.


An intra-amygdala circuit specifically regulates social fear learning.

Twining RC, Vantrease JE, Love S, Padival M, Rosenkranz JA.

Nat Neurosci. 2017 Mar;20(3):459-469. doi: 10.1038/nn.4481. Epub 2017 Jan 23.


Reply: Atherosclerosis and vascular cognitive impairment neuropathological guideline.

Skrobot OA, Attems J, Esiri M, Hortobágyi T, Ironside JW, Kalaria RN, King A, Lammie GA, Mann D, Neal J, Ben-Shlomo Y, Kehoe PG, Love S.

Brain. 2017 Feb;140(2):e13. doi: 10.1093/brain/aww305. Epub 2016 Dec 21. No abstract available.


Comparison of 2 models for gene-environment interactions: an example of simulated gene-medication interactions on systolic blood pressure in family-based data.

Fernández-Rhodes L, Hodonsky CJ, Graff M, Love SM, Howard AG, Seyerle AA, Avery CL, Chittoor G, Franceschini N, Voruganti VS, Young K, O'Connell JR, North KE, Justice AE.

BMC Proc. 2016 Oct 18;10(Suppl 7):371-377. eCollection 2016.


Genome-wide association of trajectories of systolic blood pressure change.

Justice AE, Howard AG, Chittoor G, Fernandez-Rhodes L, Graff M, Voruganti VS, Diao G, Love SM, Franceschini N, O'Connell JR, Avery CL, Young KL, North KE.

BMC Proc. 2016 Oct 18;10(Suppl 7):321-327. doi: 10.1186/s12919-016-0050-9. eCollection 2016.


The Vascular Impairment of Cognition Classification Consensus Study.

Skrobot OA, O'Brien J, Black S, Chen C, DeCarli C, Erkinjuntti T, Ford GA, Kalaria RN, Pantoni L, Pasquier F, Roman GC, Wallin A, Sachdev P, Skoog I; VICCCS group, Ben-Shlomo Y, Passmore AP, Love S, Kehoe PG.

Alzheimers Dement. 2017 Jun;13(6):624-633. doi: 10.1016/j.jalz.2016.10.007. Epub 2016 Dec 10.


A DNA methylation biomarker of alcohol consumption.

Liu C, Marioni RE, Hedman ÅK, Pfeiffer L, Tsai PC, Reynolds LM, Just AC, Duan Q, Boer CG, Tanaka T, Elks CE, Aslibekyan S, Brody JA, Kühnel B, Herder C, Almli LM, Zhi D, Wang Y, Huan T, Yao C, Mendelson MM, Joehanes R, Liang L, Love SA, Guan W, Shah S, McRae AF, Kretschmer A, Prokisch H, Strauch K, Peters A, Visscher PM, Wray NR, Guo X, Wiggins KL, Smith AK, Binder EB, Ressler KJ, Irvin MR, Absher DM, Hernandez D, Ferrucci L, Bandinelli S, Lohman K, Ding J, Trevisi L, Gustafsson S, Sandling JH, Stolk L, Uitterlinden AG, Yet I, Castillo-Fernandez JE, Spector TD, Schwartz JD, Vokonas P, Lind L, Li Y, Fornage M, Arnett DK, Wareham NJ, Sotoodehnia N, Ong KK, van Meurs JBJ, Conneely KN, Baccarelli AA, Deary IJ, Bell JT, North KE, Liu Y, Waldenberger M, London SJ, Ingelsson E, Levy D.

Mol Psychiatry. 2018 Feb;23(2):422-433. doi: 10.1038/mp.2016.192. Epub 2016 Nov 15.


Searching for a BNP standard: Glycosylated proBNP as a common calibrator enables improved comparability of commercial BNP immunoassays.

Semenov AG, Tamm NN, Apple FS, Schulz KM, Love SA, Ler R, Feygina EE, Katrukha AG.

Clin Biochem. 2017 Mar;50(4-5):181-185. doi: 10.1016/j.clinbiochem.2016.11.003. Epub 2016 Nov 5.


Discordance between ICD-Coded Myocardial Infarction and Diagnosis according to the Universal Definition of Myocardial Infarction.

Díaz-Garzón J, Sandoval Y, Smith SW, Love S, Schulz K, Thordsen SE, Johnson BK, Driver B, Jacoby K, Carlson MD, Dodd KW, Moore J, Scott NL, Bruen CA, Hatch R, Apple FS.

Clin Chem. 2017 Jan;63(1):415-419. doi: 10.1373/clinchem.2016.263764. Epub 2016 Nov 3.


Rapid Rule-Out of Acute Myocardial Injury Using a Single High-Sensitivity Cardiac Troponin I Measurement.

Sandoval Y, Smith SW, Shah AS, Anand A, Chapman AR, Love SA, Schulz K, Cao J, Mills NL, Apple FS.

Clin Chem. 2017 Jan;63(1):369-376. doi: 10.1373/clinchem.2016.264523. Epub 2016 Nov 3.


Extended post-mortem delay times should not be viewed as a deterrent to the scientific investigation of human brain tissue: a study from the Brains for Dementia Research Network Neuropathology Study Group, UK.

Robinson AC, Palmer L, Love S, Hamard M, Esiri M, Ansorge O, Lett D, Attems J, Morris C, Troakes C, Selvackadunco S, King A, Al-Sarraj S, Mann DM.

Acta Neuropathol. 2016 Nov;132(5):753-755. Epub 2016 Sep 15. No abstract available.


RADVAN: a randomised phase 2 trial of WBRT plus vandetanib for melanoma brain metastases - results and lessons learnt.

Gupta A, Roberts C, Tysoe F, Goff M, Nobes J, Lester J, Marshall E, Corner C, Wolstenholme V, Kelly C, Wise A, Collins L, Love S, Woodward M, Salisbury A, Middleton MR.

Br J Cancer. 2016 Nov 8;115(10):1193-1200. doi: 10.1038/bjc.2016.318. Epub 2016 Oct 6.


A practical guide for the identification of major sulcogyral structures of the human cortex.

Destrieux C, Terrier LM, Andersson F, Love SA, Cottier JP, Duvernoy H, Velut S, Janot K, Zemmoura I.

Brain Struct Funct. 2017 May;222(4):2001-2015. doi: 10.1007/s00429-016-1320-z. Epub 2016 Oct 5.


Resistance of Haemonchus sp. to monepantel and reduced efficacy of a derquantel / abamectin combination confirmed in sheep in NSW, Australia.

Sales N, Love S.

Vet Parasitol. 2016 Sep 15;228:193-196. doi: 10.1016/j.vetpar.2016.08.016. Epub 2016 Aug 23.


Adjuvant capecitabine plus bevacizumab versus capecitabine alone in patients with colorectal cancer (QUASAR 2): an open-label, randomised phase 3 trial.

Kerr RS, Love S, Segelov E, Johnstone E, Falcon B, Hewett P, Weaver A, Church D, Scudder C, Pearson S, Julier P, Pezzella F, Tomlinson I, Domingo E, Kerr DJ.

Lancet Oncol. 2016 Nov;17(11):1543-1557. doi: 10.1016/S1470-2045(16)30172-3. Epub 2016 Sep 19.


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