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Items: 1 to 50 of 58

1.

A novel cell-type deconvolution algorithm reveals substantial contamination by immune cells in saliva, buccal and cervix.

Zheng SC, Webster AP, Dong D, Feber A, Graham DG, Sullivan R, Jevons S, Lovat LB, Beck S, Widschwendter M, Teschendorff AE.

Epigenomics. 2018 Apr 25. doi: 10.2217/epi-2018-0037. [Epub ahead of print]

2.

Immunohistochemical assessment of Survivin and Bcl3 expression as potential biomarkers for NF-κB activation in the Barrett metaplasia-dysplasia-adenocarcinoma sequence.

Puccio I, Khan S, Butt A, Graham D, Sehgal V, Patel D, Novelli M, Lovat LB, Rodriguez-Justo M, Hamoudi RA.

Int J Exp Pathol. 2018 Feb;99(1):10-14. doi: 10.1111/iep.12260. Epub 2018 Feb 23.

PMID:
29473241
3.

Systematic assessment with I-SCAN magnification endoscopy and acetic acid improves dysplasia detection in patients with Barrett's esophagus.

Lipman G, Bisschops R, Sehgal V, Ortiz-Fernández-Sordo J, Sweis R, Esteban JM, Hamoudi R, Banks MR, Ragunath K, Lovat LB, Haidry RJ.

Endoscopy. 2017 Dec;49(12):1219-1228. doi: 10.1055/s-0043-113441. Epub 2017 Jul 21.

PMID:
28732392
4.

Risk stratification of Barrett's oesophagus using a non-endoscopic sampling method coupled with a biomarker panel: a cohort study.

Ross-Innes CS, Chettouh H, Achilleos A, Galeano-Dalmau N, Debiram-Beecham I, MacRae S, Fessas P, Walker E, Varghese S, Evan T, Lao-Sirieix PS, O'Donovan M, Malhotra S, Novelli M, Disep B, Kaye PV, Lovat LB, Haidry R, Griffin M, Ragunath K, Bhandari P, Haycock A, Morris D, Attwood S, Dhar A, Rees C, Rutter MD, Ostler R, Aigret B, Sasieni PD, Fitzgerald RC; BEST2 study group.

Lancet Gastroenterol Hepatol. 2017 Jan;2(1):23-31. doi: 10.1016/S2468-1253(16)30118-2. Epub 2016 Nov 11. Erratum in: Lancet Gastroenterol Hepatol. 2017 Jul;2(7):e4.

PMID:
28404010
5.

Upregulation of mucin glycoprotein MUC1 in the progression to esophageal adenocarcinoma and therapeutic potential with a targeted photoactive antibody-drug conjugate.

Adil Butt M, Pye H, Haidry RJ, Oukrif D, Khan SU, Puccio I, Gandy M, Reinert HW, Bloom E, Rashid M, Yahioglu G, Deonarain MP, Hamoudi R, Rodriguez-Justo M, Novelli MR, Lovat LB.

Oncotarget. 2017 Apr 11;8(15):25080-25096. doi: 10.18632/oncotarget.15340.

6.

Monitoring the premalignant potential of Barrett's oesophagus'.

Graham D, Lipman G, Sehgal V, Lovat LB.

Frontline Gastroenterol. 2016 Oct;7(4):316-322. Epub 2016 May 5. Review.

7.

A HER2 selective theranostic agent for surgical resection guidance and photodynamic therapy.

Pye H, Butt MA, Reinert HW, Maruani A, Nunes JP, Marklew JS, Qurashi M, Funnell L, May A, Stamati I, Hamoudi R, Baker JR, Smith ME, Caddick S, Deonarain MP, Yahioglu G, Chudasama V, Lovat LB.

Photochem Photobiol Sci. 2016 Oct 5;15(10):1227-1238. Epub 2016 Aug 9.

PMID:
27501936
8.

Genetic Complexity of Crohn's Disease in Two Large Ashkenazi Jewish Families.

Levine AP, Pontikos N, Schiff ER, Jostins L, Speed D; NIDDK Inflammatory Bowel Disease Genetics Consortium, Lovat LB, Barrett JC, Grasberger H, Plagnol V, Segal AW.

Gastroenterology. 2016 Oct;151(4):698-709. doi: 10.1053/j.gastro.2016.06.040. Epub 2016 Jul 1.

9.

Reply to Kristo et al.

Haidry RJ, Lipman G, Banks MR, Butt MA, Sehgal V, Graham D, Dunn JM, Gupta A, Sweis R, Miah H, Morris D, Smart HL, Bhandari P, Willert R, Fullarton G, Morris J, Di Pietro M, Gordon C, Penman I, Barr H, Patel P, Boger P, Kapoor N, Mahon B, Hoare J, Narayanasamy R, O'Toole D, Cheong E, Direkze NC, Ang Y, Veitch A, Dhar A, Nyalender D, Ragunath K, Leahy A, Fullard M, Rodriguez-Justo M, Novelli M, Lovat LB.

Endoscopy. 2016 Jan;48(1):93. doi: 10.1055/s-0035-1569618. Epub 2015 Dec 28. No abstract available.

PMID:
26710283
10.

Development of Photodynamic Antimicrobial Chemotherapy (PACT) for Clostridium difficile.

De Sordi L, Butt MA, Pye H, Kohoutova D, Mosse CA, Yahioglu G, Stamati I, Deonarain M, Battah S, Ready D, Allan E, Mullany P, Lovat LB.

PLoS One. 2015 Aug 27;10(8):e0135039. doi: 10.1371/journal.pone.0135039. eCollection 2015.

11.

Comparing outcome of radiofrequency ablation in Barrett's with high grade dysplasia and intramucosal carcinoma: a prospective multicenter UK registry.

Haidry RJ, Lipman G, Banks MR, Butt MA, Sehgal V, Graham D, Dunn JM, Gupta A, Sweis R, Miah H, Morris D, Smart HL, Bhandari P, Willert R, Fullarton G, Morris J, Di Pietro M, Gordon C, Penman I, Barr H, Patel P, Boger P, Kapoor N, Mahon B, Hoare J, Narayanasamy R, O'Toole D, Cheong E, Direkze NC, Ang Y, Veitch A, Dhar A, Nyalender D, Ragunath K, Leahy A, Fullard M, Rodriguez-Justo M, Novelli M, Lovat LB.

Endoscopy. 2015 Nov;47(11):980-7. doi: 10.1055/s-0034-1392414. Epub 2015 Jun 30.

PMID:
26126159
12.

Mass Spectrometric Analysis of Exhaled Breath for the Identification of Volatile Organic Compound Biomarkers in Esophageal and Gastric Adenocarcinoma.

Kumar S, Huang J, Abbassi-Ghadi N, Mackenzie HA, Veselkov KA, Hoare JM, Lovat LB, Španěl P, Smith D, Hanna GB.

Ann Surg. 2015 Dec;262(6):981-90. doi: 10.1097/SLA.0000000000001101.

PMID:
25575255
13.

Improvement over time in outcomes for patients undergoing endoscopic therapy for Barrett's oesophagus-related neoplasia: 6-year experience from the first 500 patients treated in the UK patient registry.

Haidry RJ, Butt MA, Dunn JM, Gupta A, Lipman G, Smart HL, Bhandari P, Smith L, Willert R, Fullarton G, Di Pietro M, Gordon C, Penman I, Barr H, Patel P, Kapoor N, Hoare J, Narayanasamy R, Ang Y, Veitch A, Ragunath K, Novelli M, Lovat LB; UK RFA Registry.

Gut. 2015 Aug;64(8):1192-9. doi: 10.1136/gutjnl-2014-308501. Epub 2014 Dec 24.

14.

Squamous cell carcinoma after radiofrequency ablation for Barrett's dysplasia.

Zeki SS, Haidry R, Justo-Rodriguez M, Lovat LB, Wright NA, McDonald SA.

World J Gastroenterol. 2014 Apr 21;20(15):4453-6. doi: 10.3748/wjg.v20.i15.4453.

15.

Gastro-esophageal reflux disease symptoms and demographic factors as a pre-screening tool for Barrett's esophagus.

Liu X, Wong A, Kadri SR, Corovic A, O'Donovan M, Lao-Sirieix P, Lovat LB, Burnham RW, Fitzgerald RC.

PLoS One. 2014 Apr 15;9(4):e94163. doi: 10.1371/journal.pone.0094163. eCollection 2014.

16.

Radiofrequency ablation for early oesophageal squamous neoplasia: outcomes form United Kingdom registry.

Haidry RJ, Butt MA, Dunn J, Banks M, Gupta A, Smart H, Bhandari P, Smith LA, Willert R, Fullarton G, John M, Di Pietro M, Penman I, Novelli M, Lovat LB.

World J Gastroenterol. 2013 Sep 28;19(36):6011-9. doi: 10.3748/wjg.v19.i36.6011.

17.

Clonal selection and persistence in dysplastic Barrett's esophagus and intramucosal cancers after failed radiofrequency ablation.

Zeki SS, Haidry R, Graham TA, Rodriguez-Justo M, Novelli M, Hoare J, Dunn J, Wright NA, Lovat LB, McDonald SA.

Am J Gastroenterol. 2013 Oct;108(10):1584-92. doi: 10.1038/ajg.2013.238. Epub 2013 Aug 13.

PMID:
23939625
18.

Radiofrequency ablation and endoscopic mucosal resection for dysplastic barrett's esophagus and early esophageal adenocarcinoma: outcomes of the UK National Halo RFA Registry.

Haidry RJ, Dunn JM, Butt MA, Burnell MG, Gupta A, Green S, Miah H, Smart HL, Bhandari P, Smith LA, Willert R, Fullarton G, Morris J, Di Pietro M, Gordon C, Penman I, Barr H, Patel P, Boger P, Kapoor N, Mahon B, Hoare J, Narayanasamy R, O'Toole D, Cheong E, Direkze NC, Ang Y, Novelli M, Banks MR, Lovat LB.

Gastroenterology. 2013 Jul;145(1):87-95. doi: 10.1053/j.gastro.2013.03.045. Epub 2013 Mar 28.

PMID:
23542069
19.

Population-based study reveals new risk-stratification biomarker panel for Barrett's esophagus.

Bird-Lieberman EL, Dunn JM, Coleman HG, Lao-Sirieix P, Oukrif D, Moore CE, Varghese S, Johnston BT, Arthur K, McManus DT, Novelli MR, O'Donovan M, Cardwell CR, Lovat LB, Murray LJ, Fitzgerald RC.

Gastroenterology. 2012 Oct;143(4):927-35.e3. doi: 10.1053/j.gastro.2012.06.041. Epub 2012 Jul 3.

PMID:
22771507
20.

Characterization of the timing and prevalence of receptor tyrosine kinase expression changes in oesophageal carcinogenesis.

Paterson AL, O'Donovan M, Provenzano E, Murray LJ, Coleman HG, Johnson BT, McManus DT, Novelli M, Lovat LB, Fitzgerald RC.

J Pathol. 2013 May;230(1):118-28. doi: 10.1002/path.4044. Epub 2013 Mar 22.

PMID:
22733579
21.

A randomised controlled trial of ALA vs. Photofrin photodynamic therapy for high-grade dysplasia arising in Barrett's oesophagus.

Dunn JM, Mackenzie GD, Banks MR, Mosse CA, Haidry R, Green S, Thorpe S, Rodriguez-Justo M, Winstanley A, Novelli MR, Bown SG, Lovat LB.

Lasers Med Sci. 2013 May;28(3):707-15. doi: 10.1007/s10103-012-1132-1. Epub 2012 Jun 15.

PMID:
22699800
22.

Consensus statements for management of Barrett's dysplasia and early-stage esophageal adenocarcinoma, based on a Delphi process.

Bennett C, Vakil N, Bergman J, Harrison R, Odze R, Vieth M, Sanders S, Gay L, Pech O, Longcroft-Wheaton G, Romero Y, Inadomi J, Tack J, Corley DA, Manner H, Green S, Al Dulaimi D, Ali H, Allum B, Anderson M, Curtis H, Falk G, Fennerty MB, Fullarton G, Krishnadath K, Meltzer SJ, Armstrong D, Ganz R, Cengia G, Going JJ, Goldblum J, Gordon C, Grabsch H, Haigh C, Hongo M, Johnston D, Forbes-Young R, Kay E, Kaye P, Lerut T, Lovat LB, Lundell L, Mairs P, Shimoda T, Spechler S, Sontag S, Malfertheiner P, Murray I, Nanji M, Poller D, Ragunath K, Regula J, Cestari R, Shepherd N, Singh R, Stein HJ, Talley NJ, Galmiche JP, Tham TC, Watson P, Yerian L, Rugge M, Rice TW, Hart J, Gittens S, Hewin D, Hochberger J, Kahrilas P, Preston S, Sampliner R, Sharma P, Stuart R, Wang K, Waxman I, Abley C, Loft D, Penman I, Shaheen NJ, Chak A, Davies G, Dunn L, Falck-Ytter Y, Decaestecker J, Bhandari P, Ell C, Griffin SM, Attwood S, Barr H, Allen J, Ferguson MK, Moayyedi P, Jankowski JA.

Gastroenterology. 2012 Aug;143(2):336-46. doi: 10.1053/j.gastro.2012.04.032. Epub 2012 Apr 24.

23.

Molecular imaging using fluorescent lectins permits rapid endoscopic identification of dysplasia in Barrett's esophagus.

Bird-Lieberman EL, Neves AA, Lao-Sirieix P, O'Donovan M, Novelli M, Lovat LB, Eng WS, Mahal LK, Brindle KM, Fitzgerald RC.

Nat Med. 2012 Jan 15;18(2):315-21. doi: 10.1038/nm.2616.

PMID:
22245781
24.

Re-localisation of a biopsy site in endoscopic images and characterisation of its uncertainty.

Allain B, Hu M, Lovat LB, Cook RJ, Vercauteren T, Ourselin S, Hawkes DJ.

Med Image Anal. 2012 Feb;16(2):482-96. doi: 10.1016/j.media.2011.11.005. Epub 2011 Dec 2.

PMID:
22197442
25.

High resolution colonoscopy in a bowel cancer screening program improves polyp detection.

Banks MR, Haidry R, Butt MA, Whitley L, Stein J, Langmead L, Bloom SL, O'Bichere A, McCartney S, Basherdas K, Rodriguez-Justo M, Lovat LB.

World J Gastroenterol. 2011 Oct 14;17(38):4308-13. doi: 10.3748/wjg.v17.i38.4308.

26.

Comparison of nuclear texture analysis and image cytometric DNA analysis for the assessment of dysplasia in Barrett's oesophagus.

Dunn JM, Hveem T, Pretorius M, Oukrif D, Nielsen B, Albregtsen F, Lovat LB, Novelli MR, Danielsen HE.

Br J Cancer. 2011 Oct 11;105(8):1218-23. doi: 10.1038/bjc.2011.353. Epub 2011 Sep 20.

27.

Radiofrequency ablation is effective for the treatment of high-grade dysplasia in Barrett's esophagus after failed photodynamic therapy.

Dunn JM, Banks MR, Oukrif D, Mackenzie GD, Thorpe S, Rodriguez-Justo M, Winstanley A, Bown SG, Novelli MR, Lovat LB.

Endoscopy. 2011 Jul;43(7):627-30. doi: 10.1055/s-0030-1256443. Epub 2011 Jun 29.

PMID:
21717379
28.

A system for biopsy site re-targeting with uncertainty in gastroenterology and oropharyngeal examinations.

Allain B, Hu M, Lovat LB, Cook RJ, Vercauteren T, Ourselin S, Hawkes DJ.

Med Image Comput Comput Assist Interv. 2010;13(Pt 2):514-21.

PMID:
20879354
29.

Image cytometry accurately detects DNA ploidy abnormalities and predicts late relapse to high-grade dysplasia and adenocarcinoma in Barrett's oesophagus following photodynamic therapy.

Dunn JM, Mackenzie GD, Oukrif D, Mosse CA, Banks MR, Thorpe S, Sasieni P, Bown SG, Novelli MR, Rabinovitch PS, Lovat LB.

Br J Cancer. 2010 May 25;102(11):1608-17. doi: 10.1038/sj.bjc.6605688. Epub 2010 May 11.

30.

Elastic scattering spectroscopy for detection of cancer risk in Barrett's esophagus: experimental and clinical validation of error removal by orthogonal subtraction for increasing accuracy.

Zhu Y, Fearn T, Mackenzie G, Clark B, Dunn JM, Bigio IJ, Bown SG, Lovat LB.

J Biomed Opt. 2009 Jul-Aug;14(4):044022. doi: 10.1117/1.3194291.

31.

Biopsy site re-localisation based on the computation of epipolar lines from two previous endoscopic images.

Allain B, Hu M, Lovat LB, Cook R, Ourselin S, Hawkes D.

Med Image Comput Comput Assist Interv. 2009;12(Pt 1):491-8.

PMID:
20426024
32.

Optimal conditions for successful ablation of high-grade dysplasia in Barrett's oesophagus using aminolaevulinic acid photodynamic therapy.

Mackenzie GD, Dunn JM, Selvasekar CR, Mosse CA, Thorpe SM, Novelli MR, Bown SG, Lovat LB.

Lasers Med Sci. 2009 Sep;24(5):729-34. doi: 10.1007/s10103-008-0630-7. Epub 2008 Dec 5.

PMID:
19057983
33.

How light dosimetry influences the efficacy of photodynamic therapy with 5-aminolaevulinic acid for ablation of high-grade dysplasia in Barrett's esophagus.

Mackenzie GD, Jamieson NF, Novelli MR, Mosse CA, Clark BR, Thorpe SM, Bown SG, Lovat LB.

Lasers Med Sci. 2008 Apr;23(2):203-10. Epub 2007 Jul 3.

PMID:
17610005
34.

Elastic scattering spectroscopy accurately detects high grade dysplasia and cancer in Barrett's oesophagus.

Lovat LB, Johnson K, Mackenzie GD, Clark BR, Novelli MR, Davies S, O'Donovan M, Selvasekar C, Thorpe SM, Pickard D, Fitzgerald R, Fearn T, Bigio I, Bown SG.

Gut. 2006 Aug;55(8):1078-83. Epub 2006 Feb 9.

35.

Elastic scattering spectroscopy for the diagnosis of colonic lesions: initial results of a novel optical biopsy technique.

Dhar A, Johnson KS, Novelli MR, Bown SG, Bigio IJ, Lovat LB, Bloom SL.

Gastrointest Endosc. 2006 Feb;63(2):257-61.

PMID:
16427931
36.

Photodynamic therapy with m-tetrahydroxyphenyl chlorin for high-grade dysplasia and early cancer in Barrett's columnar lined esophagus.

Lovat LB, Jamieson NF, Novelli MR, Mosse CA, Selvasekar C, Mackenzie GD, Thorpe SM, Bown SG.

Gastrointest Endosc. 2005 Oct;62(4):617-23.

PMID:
16185985
37.

Gastrin-induced cyclooxygenase-2 expression in Barrett's carcinogenesis.

Abdalla SI, Lao-Sirieix P, Novelli MR, Lovat LB, Sanderson IR, Fitzgerald RC.

Clin Cancer Res. 2004 Jul 15;10(14):4784-92.

38.

Nd:YAG laser induces long-term remission in transfusion-dependent patients with watermelon stomach.

Mathou NG, Lovat LB, Thorpe SM, Bown SG.

Lasers Med Sci. 2004;18(4):213-8. Epub 2004 Jan 15.

PMID:
15042426
39.

Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis.

Pepys MB, Herbert J, Hutchinson WL, Tennent GA, Lachmann HJ, Gallimore JR, Lovat LB, Bartfai T, Alanine A, Hertel C, Hoffmann T, Jakob-Roetne R, Norcross RD, Kemp JA, Yamamura K, Suzuki M, Taylor GW, Murray S, Thompson D, Purvis A, Kolstoe S, Wood SP, Hawkins PN.

Nature. 2002 May 16;417(6886):254-9.

PMID:
12015594
40.

Photodynamic therapy for cancer of the pancreas.

Bown SG, Rogowska AZ, Whitelaw DE, Lees WR, Lovat LB, Ripley P, Jones L, Wyld P, Gillams A, Hatfield AW.

Gut. 2002 Apr;50(4):549-57.

41.

Lasers in gastroenterology.

Lovat LB, Bown SG.

World J Gastroenterol. 2001 Jun;7(3):317-23. Review. No abstract available.

42.

Laser augmented by brachytherapy versus laser alone in the palliation of adenocarcinoma of the oesophagus and cardia: a randomised study.

Spencer GM, Thorpe SM, Blackman GM, Solano J, Tobias JS, Lovat LB, Bown SG.

Gut. 2002 Feb;50(2):224-7.

43.

Amyloid load and clinical outcome in AA amyloidosis in relation to circulating concentration of serum amyloid A protein.

Gillmore JD, Lovat LB, Persey MR, Pepys MB, Hawkins PN.

Lancet. 2001 Jul 7;358(9275):24-9.

PMID:
11454373
44.

The biology of photodynamic therapy in the gastrointestinal tract.

Bown SG, Lovat LB.

Gastrointest Endosc Clin N Am. 2000 Jul;10(3):533-50. Review.

PMID:
10899262
45.

Amyloidosis and the liver.

Gillmore JD, Lovat LB, Hawkins PN.

J Hepatol. 1999;30 Suppl 1:17-33. Review. No abstract available.

PMID:
10370897
46.

Scintigraphy with 123I-serum amyloid P component in Alzheimer disease.

Lovat LB, O'Brien AA, Armstrong SF, Madhoo S, Bulpitt CJ, Rossor MN, Pepys MB, Hawkins PN.

Alzheimer Dis Assoc Disord. 1998 Sep;12(3):208-10.

PMID:
9772025
47.

The liver in systemic amyloidosis: insights from 123I serum amyloid P component scintigraphy in 484 patients.

Lovat LB, Persey MR, Madhoo S, Pepys MB, Hawkins PN.

Gut. 1998 May;42(5):727-34.

48.

Amyloid and the gut.

Lovat LB, Pepys MB, Hawkins PN.

Dig Dis. 1997 May-Jun;15(3):155-71. Review.

PMID:
9158925
49.

Long-term survival in systemic amyloid A amyloidosis complicating Crohn's disease.

Lovat LB, Madhoo S, Pepys MB, Hawkins PN.

Gastroenterology. 1997 Apr;112(4):1362-5.

PMID:
9098022
50.

Nutritional supplementation in elderly medical in-patients: a double-blind placebo-controlled trial.

Hogarth MB, Marshall P, Lovat LB, Palmer AJ, Frost CG, Fletcher AE, Nicholl CG, Bulpitt CJ.

Age Ageing. 1996 Nov;25(6):453-7.

PMID:
9003882

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