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Items: 1 to 50 of 428

1.

Mutations in ERGIC1 cause Arthrogryposis multiplex congenita, neuropathic type.

Reinstein E, Drasinover V, Lotan R, Gal-Tanamy M, Bolocan Nachman I, Eyal E, Jaber L, Magal N, Shohat M.

Clin Genet. 2018 Jan;93(1):160-163. doi: 10.1111/cge.13018. Epub 2017 Jul 26.

PMID:
28317099
2.

Non-alcoholic fatty liver disease is not associated with a lower health perception.

Mlynarsky L, Schlesinger D, Lotan R, Webb M, Halpern Z, Santo E, Shibolet O, Zelber-Sagi S.

World J Gastroenterol. 2016 May 7;22(17):4362-72. doi: 10.3748/wjg.v22.i17.4362.

3.

Patients with chronic non-specific low back pain who reported reduction in pain and improvement in function also demonstrated an improvement in gait pattern.

Barzilay Y, Segal G, Lotan R, Regev G, Beer Y, Lonner BS, Mor A, Elbaz A.

Eur Spine J. 2016 Sep;25(9):2761-6. doi: 10.1007/s00586-015-4004-0. Epub 2015 May 16.

PMID:
25981205
4.

Coffee consumption and nonalcoholic fatty liver onset: a prospective study in the general population.

Zelber-Sagi S, Salomone F, Webb M, Lotan R, Yeshua H, Halpern Z, Santo E, Oren R, Shibolet O.

Transl Res. 2015 Mar;165(3):428-36. doi: 10.1016/j.trsl.2014.10.008. Epub 2014 Oct 17.

PMID:
25468486
5.

Non-high-density lipoprotein cholesterol independently predicts new onset of non-alcoholic fatty liver disease.

Zelber-Sagi S, Salomone F, Yeshua H, Lotan R, Webb M, Halpern Z, Santo E, Oren R, Shibolet O.

Liver Int. 2014 Jul;34(6):e128-35. doi: 10.1111/liv.12318. Epub 2013 Oct 14.

PMID:
24118857
6.

Non-alcoholic fatty liver disease independently predicts prediabetes during a 7-year prospective follow-up.

Zelber-Sagi S, Lotan R, Shibolet O, Webb M, Buch A, Nitzan-Kaluski D, Halpern Z, Santo E, Oren R.

Liver Int. 2013 Oct;33(9):1406-12. doi: 10.1111/liv.12200. Epub 2013 May 8.

PMID:
23656177
7.

G-protein coupled receptor family C, group 5, member A (GPRC5A) expression is decreased in the adjacent field and normal bronchial epithelia of patients with chronic obstructive pulmonary disease and non-small-cell lung cancer.

Fujimoto J, Kadara H, Garcia MM, Kabbout M, Behrens C, Liu DD, Lee JJ, Solis LM, Kim ES, Kalhor N, Moran C, Sharafkhaneh A, Lotan R, Wistuba II.

J Thorac Oncol. 2012 Dec;7(12):1747-54. doi: 10.1097/JTO.0b013e31826bb1ff.

8.

Genetic variants in the PI3K/PTEN/AKT/mTOR pathway predict head and neck cancer patient second primary tumor/recurrence risk and response to retinoid chemoprevention.

Hildebrandt MA, Lippman SM, Etzel CJ, Kim E, Lee JJ, Khuri FR, Spitz MR, Lotan R, Hong WK, Wu X.

Clin Cancer Res. 2012 Jul 1;18(13):3705-13. doi: 10.1158/1078-0432.CCR-11-3271. Epub 2012 May 10.

9.

Predictors for incidence and remission of NAFLD in the general population during a seven-year prospective follow-up.

Zelber-Sagi S, Lotan R, Shlomai A, Webb M, Harrari G, Buch A, Nitzan Kaluski D, Halpern Z, Oren R.

J Hepatol. 2012 May;56(5):1145-51. doi: 10.1016/j.jhep.2011.12.011. Epub 2012 Jan 13.

PMID:
22245895
10.

Enhancement of lung tumorigenesis in a Gprc5a Knockout mouse by chronic extrinsic airway inflammation.

Barta P, Van Pelt C, Men T, Dickey BF, Lotan R, Moghaddam SJ.

Mol Cancer. 2012 Jan 12;11:4. doi: 10.1186/1476-4598-11-4.

11.

Mechanistic contribution of ubiquitous 15-lipoxygenase-1 expression loss in cancer cells to terminal cell differentiation evasion.

Moussalli MJ, Wu Y, Zuo X, Yang XL, Wistuba II, Raso MG, Morris JS, Bowser JL, Minna JD, Lotan R, Shureiqi I.

Cancer Prev Res (Phila). 2011 Dec;4(12):1961-72. doi: 10.1158/1940-6207.CAPR-10-0280. Epub 2011 Aug 31.

12.

Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.

Zhao M, Sano D, Pickering CR, Jasser SA, Henderson YC, Clayman GL, Sturgis EM, Ow TJ, Lotan R, Carey TE, Sacks PG, Grandis JR, Sidransky D, Heldin NE, Myers JN.

Clin Cancer Res. 2011 Dec 1;17(23):7248-64. doi: 10.1158/1078-0432.CCR-11-0690. Epub 2011 Aug 25.

13.

Global assessment of genetic variation influencing response to retinoid chemoprevention in head and neck cancer patients.

Lee JJ, Wu X, Hildebrandt MA, Yang H, Khuri FR, Kim E, Gu J, Ye Y, Lotan R, Spitz MR, Hong WK.

Cancer Prev Res (Phila). 2011 Feb;4(2):185-93. doi: 10.1158/1940-6207.CAPR-10-0125.

14.

A five-gene and corresponding protein signature for stage-I lung adenocarcinoma prognosis.

Kadara H, Behrens C, Yuan P, Solis L, Liu D, Gu X, Minna JD, Lee JJ, Kim E, Hong WK, Wistuba II, Lotan R.

Clin Cancer Res. 2011 Mar 15;17(6):1490-501. doi: 10.1158/1078-0432.CCR-10-2703. Epub 2010 Dec 16.

15.

Gprc5a deletion enhances the transformed phenotype in normal and malignant lung epithelial cells by eliciting persistent Stat3 signaling induced by autocrine leukemia inhibitory factor.

Chen Y, Deng J, Fujimoto J, Kadara H, Men T, Lotan D, Lotan R.

Cancer Res. 2010 Nov 1;70(21):8917-26. doi: 10.1158/0008-5472.CAN-10-0518. Epub 2010 Oct 19.

16.

MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer.

Zhang X, Yang H, Lee JJ, Kim E, Lippman SM, Khuri FR, Spitz MR, Lotan R, Hong WK, Wu X.

Carcinogenesis. 2010 Dec;31(12):2118-23. doi: 10.1093/carcin/bgq177. Epub 2010 Sep 5.

17.

Slow-release human recombinant bone morphogenetic protein-2 embedded within electrospun scaffolds for regeneration of bone defect: in vitro and in vivo evaluation.

Srouji S, Ben-David D, Lotan R, Livne E, Avrahami R, Zussman E.

Tissue Eng Part A. 2011 Feb;17(3-4):269-77. doi: 10.1089/ten.TEA.2010.0250. Epub 2010 Nov 4.

PMID:
20799887
18.

Comparative functional genomics analysis of NNK tobacco-carcinogen induced lung adenocarcinoma development in Gprc5a-knockout mice.

Fujimoto J, Kadara H, Men T, van Pelt C, Lotan D, Lotan R.

PLoS One. 2010 Jul 29;5(7):e11847. doi: 10.1371/journal.pone.0011847.

19.

Validation of a novel statistical model for assessing the synergy of combined-agent cancer chemoprevention.

Fujimoto J, Kong M, Lee JJ, Hong WK, Lotan R.

Cancer Prev Res (Phila). 2010 Aug;3(8):917-28. doi: 10.1158/1940-6207.CAPR-10-0129. Epub 2010 Jul 27.

20.

Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma.

Wang J, Lippman SM, Lee JJ, Yang H, Khuri FR, Kim E, Lin J, Chang DW, Lotan R, Hong WK, Wu X.

Carcinogenesis. 2010 Oct;31(10):1755-61. doi: 10.1093/carcin/bgq138. Epub 2010 Jul 12.

21.

Clinical features of conjoined lumbosacral nerve roots versus lumbar intervertebral disc herniations.

Lotan R, Al-Rashdi A, Yee A, Finkelstein J.

Eur Spine J. 2010 Jul;19(7):1094-8. doi: 10.1007/s00586-010-1329-6. Epub 2010 Feb 21.

22.
23.

Mortality in the randomized, controlled lung intergroup trial of isotretinoin.

Lee JJ, Feng L, Reshef DS, Sabichi AL, Williams B, Rinsurongkawong W, Wistuba II, Lotan R, Lippman SM.

Cancer Prev Res (Phila). 2010 Jun;3(6):738-44. doi: 10.1158/1940-6207.CAPR-09-0124. Epub 2010 May 25.

24.

Diabetes mellitus as a risk factor for the development of lumbar spinal stenosis.

Anekstein Y, Smorgick Y, Lotan R, Agar G, Shalmon E, Floman Y, Mirovsky Y.

Isr Med Assoc J. 2010 Jan;12(1):16-20.

25.

The innate osteogenic potential of the maxillary sinus (Schneiderian) membrane: an ectopic tissue transplant model simulating sinus lifting.

Srouji S, Ben-David D, Lotan R, Riminucci M, Livne E, Bianco P.

Int J Oral Maxillofac Surg. 2010 Aug;39(8):793-801. doi: 10.1016/j.ijom.2010.03.009. Epub 2010 Apr 22.

PMID:
20417057
26.

Knockout of the tumor suppressor gene Gprc5a in mice leads to NF-kappaB activation in airway epithelium and promotes lung inflammation and tumorigenesis.

Deng J, Fujimoto J, Ye XF, Men TY, Van Pelt CS, Chen YL, Lin XF, Kadara H, Tao Q, Lotan D, Lotan R.

Cancer Prev Res (Phila). 2010 Apr;3(4):424-37. doi: 10.1158/1940-6207.CAPR-10-0032. Epub 2010 Mar 30.

27.

Differential inhibition of protein translation machinery by curcumin in normal, immortalized, and malignant oral epithelial cells.

Chakravarti N, Kadara H, Yoon DJ, Shay JW, Myers JN, Lotan D, Sonenberg N, Lotan R.

Cancer Prev Res (Phila). 2010 Mar;3(3):331-8. doi: 10.1158/1940-6207.CAPR-09-0076. Epub 2010 Feb 9.

28.

Biological activity of celecoxib in the bronchial epithelium of current and former smokers.

Kim ES, Hong WK, Lee JJ, Mao L, Morice RC, Liu DD, Jimenez CA, Eapen GA, Lotan R, Tang X, Newman RA, Wistuba II, Kurie JM.

Cancer Prev Res (Phila). 2010 Feb;3(2):148-59. doi: 10.1158/1940-6207.CAPR-09-0233. Epub 2010 Jan 26.

29.

Expression of interleukin-1 receptor-associated kinase-1 in non-small cell lung carcinoma and preneoplastic lesions.

Behrens C, Feng L, Kadara H, Kim HJ, Lee JJ, Mehran R, Hong WK, Lotan R, Wistuba II.

Clin Cancer Res. 2010 Jan 1;16(1):34-44. doi: 10.1158/1078-0432.CCR-09-0650. Epub 2009 Dec 22.

30.

Galectin-3 increases gastric cancer cell motility by up-regulating fascin-1 expression.

Kim SJ, Choi IJ, Cheong TC, Lee SJ, Lotan R, Park SH, Chun KH.

Gastroenterology. 2010 Mar;138(3):1035-45.e1-2. doi: 10.1053/j.gastro.2009.09.061. Epub 2009 Oct 8.

PMID:
19818782
31.

Curcumin inhibits COPD-like airway inflammation and lung cancer progression in mice.

Moghaddam SJ, Barta P, Mirabolfathinejad SG, Ammar-Aouchiche Z, Garza NT, Vo TT, Newman RA, Aggarwal BB, Evans CM, Tuvim MJ, Lotan R, Dickey BF.

Carcinogenesis. 2009 Nov;30(11):1949-56. doi: 10.1093/carcin/bgp229. Epub 2009 Sep 30.

32.

Identification of gene signatures and molecular markers for human lung cancer prognosis using an in vitro lung carcinogenesis system.

Kadara H, Lacroix L, Behrens C, Solis L, Gu X, Lee JJ, Tahara E, Lotan D, Hong WK, Wistuba II, Lotan R.

Cancer Prev Res (Phila). 2009 Aug;2(8):702-11. doi: 10.1158/1940-6207.CAPR-09-0084. Epub 2009 Jul 28.

33.

Novel susceptibility loci for second primary tumors/recurrence in head and neck cancer patients: large-scale evaluation of genetic variants.

Wu X, Spitz MR, Lee JJ, Lippman SM, Ye Y, Yang H, Khuri FR, Kim E, Gu J, Lotan R, Hong WK.

Cancer Prev Res (Phila). 2009 Jul;2(7):617-24. doi: 10.1158/1940-6207.CAPR-09-0025.

34.

Expression of the receptor tyrosine kinase EphA2 is increased in smokers and predicts poor survival in non-small cell lung cancer.

Brannan JM, Dong W, Prudkin L, Behrens C, Lotan R, Bekele BN, Wistuba I, Johnson FM.

Clin Cancer Res. 2009 Jul 1;15(13):4423-30. doi: 10.1158/1078-0432.CCR-09-0473. Epub 2009 Jun 16.

35.

Activation of protein kinase C by phorbol 12-myristate 13-acetate suppresses the growth of lung cancer cells through KLF6 induction.

Tahara E, Kadara H, Lacroix L, Lotan D, Lotan R.

Cancer Biol Ther. 2009 May;8(9):801-7. Epub 2009 May 17.

PMID:
19333010
36.

Mechanisms underlying the induction of the putative human tumor suppressor GPRC5A by retinoic acid.

Ye X, Tao Q, Wang Y, Cheng Y, Lotan R.

Cancer Biol Ther. 2009 May;8(10):951-62. Epub 2009 May 20.

PMID:
19279407
37.

Algorithmic guided screening of drug combinations of arbitrary size for activity against cancer cells.

Zinner RG, Barrett BL, Popova E, Damien P, Volgin AY, Gelovani JG, Lotan R, Tran HT, Pisano C, Mills GB, Mao L, Hong WK, Lippman SM, Miller JH.

Mol Cancer Ther. 2009 Mar;8(3):521-32. doi: 10.1158/1535-7163.MCT-08-0937. Epub 2009 Mar 10.

38.

Antitumor effect of retinoic acid receptor-beta2 associated with suppression of cyclooxygenase-2.

Song S, Guan B, Men T, Hoque A, Lotan R, Xu XC.

Cancer Prev Res (Phila). 2009 Mar;2(3):274-80. doi: 10.1158/1940-6207.CAPR-08-0180. Epub 2009 Mar 3.

39.

High-dose fenretinide in oral leukoplakia.

William WN Jr, Lee JJ, Lippman SM, Martin JW, Chakravarti N, Tran HT, Sabichi AL, Kim ES, Feng L, Lotan R, Papadimitrakopoulou VA.

Cancer Prev Res (Phila). 2009 Jan;2(1):22-6. doi: 10.1158/1940-6207.CAPR-08-0100.

40.

Cancer chemoprevention and mitochondria: targeting apoptosis in transformed cells via the disruption of mitochondrial bioenergetics/redox state.

Hail N Jr, Lotan R.

Mol Nutr Food Res. 2009 Jan;53(1):49-67. doi: 10.1002/mnfr.200700527. Review.

PMID:
19051186
41.

Immunohistochemical expression of basic fibroblast growth factor and fibroblast growth factor receptors 1 and 2 in the pathogenesis of lung cancer.

Behrens C, Lin HY, Lee JJ, Raso MG, Hong WK, Wistuba II, Lotan R.

Clin Cancer Res. 2008 Oct 1;14(19):6014-22. doi: 10.1158/1078-0432.CCR-08-0167.

42.

Transcription in the nucleus and mRNA decay in the cytoplasm are coupled processes.

Goler-Baron V, Selitrennik M, Barkai O, Haimovich G, Lotan R, Choder M.

Genes Dev. 2008 Aug 1;22(15):2022-7. doi: 10.1101/gad.473608.

43.

Lumbar stenosis and systemic diseases: is there any relevance?

Lotan R, Oron A, Anekstein Y, Shalmon E, Mirovsky Y.

J Spinal Disord Tech. 2008 Jun;21(4):247-51. doi: 10.1097/BSD.0b013e31813707af.

PMID:
18525484
44.

Involvement of Rac in fenretinide-induced apoptosis.

Kadara H, Tahara E, Kim HJ, Lotan D, Myers J, Lotan R.

Cancer Res. 2008 Jun 1;68(11):4416-23. doi: 10.1158/0008-5472.CAN-08-0031.

45.

Potential misinterpretation of data on differential gene expression in normal and malignant cells in vitro.

Ye X, Lotan R.

Brief Funct Genomic Proteomic. 2008 Jul;7(4):322-6. doi: 10.1093/bfgp/eln021. Epub 2008 May 8.

PMID:
18467351
46.

Prevention of bladder cancer recurrence by retinoic acid-ketoconazole: a promising strategy?

Lotan Y, Lotan R.

Cancer Biol Ther. 2008 Jan;7(1):101-2. Epub 2008 Feb 21. No abstract available.

PMID:
18347420
48.

Identification of the retinoic acid-inducible Gprc5a as a new lung tumor suppressor gene.

Tao Q, Fujimoto J, Men T, Ye X, Deng J, Lacroix L, Clifford JL, Mao L, Van Pelt CS, Lee JJ, Lotan D, Lotan R.

J Natl Cancer Inst. 2007 Nov 21;99(22):1668-82. Epub 2007 Nov 13.

PMID:
18000218
49.

Proliferative changes in the bronchial epithelium of former smokers treated with retinoids.

Hittelman WN, Liu DD, Kurie JM, Lotan R, Lee JS, Khuri F, Ibarguen H, Morice RC, Walsh G, Roth JA, Minna J, Ro JY, Broxson A, Hong WK, Lee JJ.

J Natl Cancer Inst. 2007 Nov 7;99(21):1603-12. Epub 2007 Oct 30.

50.

The Rpb7p subunit of yeast RNA polymerase II plays roles in the two major cytoplasmic mRNA decay mechanisms.

Lotan R, Goler-Baron V, Duek L, Haimovich G, Choder M.

J Cell Biol. 2007 Sep 24;178(7):1133-43. Epub 2007 Sep 17.

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