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Pan-Trk Immunohistochemistry Identifies NTRK rearrangements in Pediatric Mesenchymal Tumors.

Rudzinski ER, Lockwood CM, Stohr BA, Vargas SO, Sheridan R, Black JO, Rajaram V, Laetsch TW, Davis JL.

Am J Surg Pathol. 2018 Apr 20. doi: 10.1097/PAS.0000000000001062. [Epub ahead of print]


Microsatellite instability in prostate cancer by PCR or next-generation sequencing.

Hempelmann JA, Lockwood CM, Konnick EQ, Schweizer MT, Antonarakis ES, Lotan TL, Montgomery B, Nelson PS, Klemfuss N, Salipante SJ, Pritchard CC.

J Immunother Cancer. 2018 Apr 17;6(1):29. doi: 10.1186/s40425-018-0341-y.


Biomarkers associated with low, moderate, and high vastus lateralis muscle hypertrophy following 12 weeks of resistance training.

Mobley CB, Haun CT, Roberson PA, Mumford PW, Kephart WC, Romero MA, Osburn SC, Vann CG, Young KC, Beck DT, Martin JS, Lockwood CM, Roberts MD.

PLoS One. 2018 Apr 5;13(4):e0195203. doi: 10.1371/journal.pone.0195203. eCollection 2018.


Circulating Tumor DNA Analysis in Patients With Cancer: American Society of Clinical Oncology and College of American Pathologists Joint Review.

Merker JD, Oxnard GR, Compton C, Diehn M, Hurley P, Lazar AJ, Lindeman N, Lockwood CM, Rai AJ, Schilsky RL, Tsimberidou AM, Vasalos P, Billman BL, Oliver TK, Bruinooge SS, Hayes DF, Turner NC.

J Clin Oncol. 2018 Mar 5:JCO2017768671. doi: 10.1200/JCO.2017.76.8671. [Epub ahead of print]


Circulating Tumor DNA Analysis in Patients With Cancer: American Society of Clinical Oncology and College of American Pathologists Joint Review.

Merker JD, Oxnard GR, Compton C, Diehn M, Hurley P, Lazar AJ, Lindeman N, Lockwood CM, Rai AJ, Schilsky RL, Tsimberidou AM, Vasalos P, Billman BL, Oliver TK, Bruinooge SS, Hayes DF, Turner NC.

Arch Pathol Lab Med. 2018 Mar 5. doi: 10.5858/arpa.2018-0901-SA. [Epub ahead of print]


Acute and chronic resistance training downregulates select LINE-1 retrotransposon activity markers in human skeletal muscle.

Romero MA, Mobley CB, Mumford PW, Roberson PA, Haun CT, Kephart WC, Healy JC, Beck DT, Young KC, Martin JS, Lockwood CM, Roberts MD.

Am J Physiol Cell Physiol. 2018 Mar 1;314(3):C379-C388. doi: 10.1152/ajpcell.00192.2017. Epub 2017 Dec 20.


Genomic heterogeneity of ALK fusion breakpoints in non-small-cell lung cancer.

Rosenbaum JN, Bloom R, Forys JT, Hiken J, Armstrong JR, Branson J, McNulty S, Velu PD, Pepin K, Abel H, Cottrell CE, Pfeifer JD, Kulkarni S, Govindan R, Konnick EQ, Lockwood CM, Duncavage EJ.

Mod Pathol. 2018 May;31(5):791-808. doi: 10.1038/modpathol.2017.181. Epub 2018 Jan 12.


Effects of Whey, Soy or Leucine Supplementation with 12 Weeks of Resistance Training on Strength, Body Composition, and Skeletal Muscle and Adipose Tissue Histological Attributes in College-Aged Males.

Mobley CB, Haun CT, Roberson PA, Mumford PW, Romero MA, Kephart WC, Anderson RG, Vann CG, Osburn SC, Pledge CD, Martin JS, Young KC, Goodlett MD, Pascoe DD, Lockwood CM, Roberts MD.

Nutrients. 2017 Sep 4;9(9). pii: E972. doi: 10.3390/nu9090972.


Targeted Next-Generation Sequencing of Acute Leukemia.

Konnick E, Lockwood CM, Wu D.

Methods Mol Biol. 2017;1633:163-184. doi: 10.1007/978-1-4939-7142-8_11.


Infantile NTRK-associated Mesenchymal Tumors.

Davis JL, Lockwood CM, Albert CM, Tsuchiya K, Hawkins DS, Rudzinski ER.

Pediatr Dev Pathol. 2018 Jan-Feb;21(1):68-78. doi: 10.1177/1093526617712639. Epub 2017 Jul 6.


Whey protein-derived exosomes increase protein synthesis and hypertrophy in C2-C12 myotubes.

Mobley CB, Mumford PW, McCarthy JJ, Miller ME, Young KC, Martin JS, Beck DT, Lockwood CM, Roberts MD.

J Dairy Sci. 2017 Jan;100(1):48-64. doi: 10.3168/jds.2016-11341. Epub 2016 Oct 27.


Variability in, variability out: best practice recommendations to standardize pre-analytical variables in the detection of circulating and tissue microRNAs.

Khan J, Lieberman JA, Lockwood CM.

Clin Chem Lab Med. 2017 May 1;55(5):608-621. doi: 10.1515/cclm-2016-0471. Review.


Effects of Hydrolyzed Whey versus Other Whey Protein Supplements on the Physiological Response to 8 Weeks of Resistance Exercise in College-Aged Males.

Lockwood CM, Roberts MD, Dalbo VJ, Smith-Ryan AE, Kendall KL, Moon JR, Stout JR.

J Am Coll Nutr. 2017 Jan;36(1):16-27. doi: 10.1080/07315724.2016.1140094. Epub 2016 Oct 6.


Unexpected Challenges in Noninvasive Prenatal Testing.

Lockwood CM.

Clin Chem. 2015 Dec;61(12):1551-2. No abstract available.


Western diet-induced hepatic steatosis and alterations in the liver transcriptome in adult Brown-Norway rats.

Roberts MD, Mobley CB, Toedebush RG, Heese AJ, Zhu C, Krieger AE, Cruthirds CL, Lockwood CM, Hofheins JC, Wiedmeyer CE, Leidy HJ, Booth FW, Rector RS.

BMC Gastroenterol. 2015 Oct 30;15:151. doi: 10.1186/s12876-015-0382-3.


Effects of oral phosphatidic acid feeding with or without whey protein on muscle protein synthesis and anabolic signaling in rodent skeletal muscle.

Mobley CB, Hornberger TA, Fox CD, Healy JC, Ferguson BS, Lowery RP, McNally RM, Lockwood CM, Stout JR, Kavazis AN, Wilson JM, Roberts MD.

J Int Soc Sports Nutr. 2015 Aug 16;12:32. doi: 10.1186/s12970-015-0094-7. eCollection 2015.


T-cell clonality assessment by next-generation sequencing improves detection sensitivity in mycosis fungoides.

Sufficool KE, Lockwood CM, Abel HJ, Hagemann IS, Schumacher JA, Kelley TW, Duncavage EJ.

J Am Acad Dermatol. 2015 Aug;73(2):228-36.e2. doi: 10.1016/j.jaad.2015.04.030. Epub 2015 Jun 3.


Effects of protein type and composition on postprandial markers of skeletal muscle anabolism, adipose tissue lipolysis, and hypothalamic gene expression.

Mobley CB, Fox CD, Ferguson BS, Pascoe CA, Healy JC, McAdam JS, Lockwood CM, Roberts MD.

J Int Soc Sports Nutr. 2015 Mar 13;12:14. doi: 10.1186/s12970-015-0076-9. eCollection 2015.


A 5-month-old boy with delay in growth and development and decreased muscle tone.

Hucthagowder V, Shinawi M, Lockwood CM.

Clin Chem. 2015 Jan;61(1):50-4. doi: 10.1373/clinchem.2014.228486. No abstract available.


Clinical next-generation sequencing in patients with non-small cell lung cancer.

Hagemann IS, Devarakonda S, Lockwood CM, Spencer DH, Guebert K, Bredemeyer AJ, Al-Kateb H, Nguyen TT, Duncavage EJ, Cottrell CE, Kulkarni S, Nagarajan R, Seibert K, Baggstrom M, Waqar SN, Pfeifer JD, Morgensztern D, Govindan R.

Cancer. 2015 Feb 15;121(4):631-9. doi: 10.1002/cncr.29089. Epub 2014 Oct 24.


Newborn screening by whole-genome sequencing: ready for prime time?

Fleischer JA, Lockwood CM.

Clin Chem. 2014 Sep;60(9):1243-4. doi: 10.1373/clinchem.2014.226076. Epub 2014 Aug 28. No abstract available.


Oral adenosine-5'-triphosphate (ATP) administration increases blood flow following exercise in animals and humans.

Jäger R, Roberts MD, Lowery RP, Joy JM, Cruthirds CL, Lockwood CM, Rathmacher JA, Purpura M, Wilson JM.

J Int Soc Sports Nutr. 2014 Jun 13;11:28. doi: 10.1186/1550-2783-11-28. eCollection 2014.


Herbal adaptogens combined with protein fractions from bovine colostrum and hen egg yolk reduce liver TNF-α expression and protein carbonylation in Western diet feeding in rats.

Mobley CB, Toedebusch RG, Lockwood CM, Heese AJ, Zhu C, Krieger AE, Cruthirds CL, Hofheins JC, Company JM, Wiedmeyer CE, Kim DY, Booth FW, Roberts MD.

Nutr Metab (Lond). 2014 Apr 23;11:19. doi: 10.1186/1743-7075-11-19. eCollection 2014.


Detection of gene rearrangements in targeted clinical next-generation sequencing.

Abel HJ, Al-Kateb H, Cottrell CE, Bredemeyer AJ, Pritchard CC, Grossmann AH, Wallander ML, Pfeifer JD, Lockwood CM, Duncavage EJ.

J Mol Diagn. 2014 Jul;16(4):405-17. doi: 10.1016/j.jmoldx.2014.03.006. Epub 2014 May 9.


Development of an immunoassay for the kidney-specific protein myo-inositol oxygenase, a potential biomarker of acute kidney injury.

Gaut JP, Crimmins DL, Ohlendorf MF, Lockwood CM, Griest TA, Brada NA, Hoshi M, Sato B, Hotchkiss RS, Jain S, Ladenson JH.

Clin Chem. 2014 May;60(5):747-57. doi: 10.1373/clinchem.2013.212993. Epub 2014 Jan 31.


Comparing serum responses to acute feedings of an extensively hydrolyzed whey protein concentrate versus a native whey protein concentrate in rats: a metabolomics approach.

Roberts MD, Cruthirds CL, Lockwood CM, Pappan K, Childs TE, Company JM, Brown JD, Toedebusch RG, Booth FW.

Appl Physiol Nutr Metab. 2014 Feb;39(2):158-67. doi: 10.1139/apnm-2013-0148. Epub 2013 Jul 30.



Lockwood CM.

Clin Chem. 2014 Feb;60(2):305-6. doi: 10.1373/clinchem.2013.210864. No abstract available.


Diagnostic utility of targeted next-generation sequencing in problematic cases.

Sehn JK, Hagemann IS, Pfeifer JD, Cottrell CE, Lockwood CM.

Am J Surg Pathol. 2014 Apr;38(4):534-41. doi: 10.1097/PAS.0000000000000161.


Design of targeted, capture-based, next generation sequencing tests for precision cancer therapy.

Hagemann IS, Cottrell CE, Lockwood CM.

Cancer Genet. 2013 Dec;206(12):420-31. doi: 10.1016/j.cancergen.2013.11.003. Epub 2013 Nov 22. Review.


Premenopausal amenorrhea: what's in a number?

Nerenz RD, Jungheim ES, Lockwood CM.

Clin Chem. 2014 Jan;60(1):29-33; discussion 33-4. doi: 10.1373/clinchem.2013.202499. No abstract available.


Effects of oral adenosine-5'-triphosphate supplementation on athletic performance, skeletal muscle hypertrophy and recovery in resistance-trained men.

Wilson JM, Joy JM, Lowery RP, Roberts MD, Lockwood CM, Manninen AH, Fuller JC, De Souza EO, Baier SM, Wilson SM, Rathmacher JA.

Nutr Metab (Lond). 2013 Sep 22;10(1):57. doi: 10.1186/1743-7075-10-57.


Clinical genomicist workstation.

Sharma MK, Phillips J, Agarwal S, Wiggins WS, Shrivastava S, Koul SB, Bhattacharjee M, Houchins CD, Kalakota RR, George B, Meyer RR, Spencer DH, Lockwood CM, Nguyen TT, Duncavage EJ, Al-Kateb H, Cottrell CE, Godala S, Lokineni R, Sawant SM, Chatti V, Surampudi S, Sunkishala RR, Darbha R, Macharla S, Milbrandt JD, Virgin HW, Mitra RD, Head RD, Kulkarni S, Bredemeyer A, Pfeifer JD, Seibert K, Nagarajan R.

AMIA Jt Summits Transl Sci Proc. 2013 Mar 18;2013:156-7. eCollection 2013.


Validation of a next-generation sequencing assay for clinical molecular oncology.

Cottrell CE, Al-Kateb H, Bredemeyer AJ, Duncavage EJ, Spencer DH, Abel HJ, Lockwood CM, Hagemann IS, O'Guin SM, Burcea LC, Sawyer CS, Oschwald DM, Stratman JL, Sher DA, Johnson MR, Brown JT, Cliften PF, George B, McIntosh LD, Shrivastava S, Nguyen TT, Payton JE, Watson MA, Crosby SD, Head RD, Mitra RD, Nagarajan R, Kulkarni S, Seibert K, Virgin HW 4th, Milbrandt J, Pfeifer JD.

J Mol Diagn. 2014 Jan;16(1):89-105. doi: 10.1016/j.jmoldx.2013.10.002. Epub 2013 Nov 6.


Clinical utility of miRNAs in diagnosis and prognosis.

Tsongalis GJ, Lockwood CM.

Clin Biochem. 2013 Jul;46(10-11):839. doi: 10.1016/j.clinbiochem.2013.05.062. No abstract available.


Circulating miR-122 as a potential biomarker of liver disease.

Laterza OF, Scott MG, Garrett-Engele PW, Korenblat KM, Lockwood CM.

Biomark Med. 2013 Apr;7(2):205-10. doi: 10.2217/bmm.12.107.


Pre-analytical variables in miRNA analysis.

Becker N, Lockwood CM.

Clin Biochem. 2013 Jul;46(10-11):861-8. doi: 10.1016/j.clinbiochem.2013.02.015. Epub 2013 Mar 4. Review.


Expression of the Na+/K+-transporting ATPase gamma subunit FXYD2 in renal tumors.

Gaut JP, Crimmins DL, Lockwood CM, McQuillan JJ, Ladenson JH.

Mod Pathol. 2013 May;26(5):716-24. doi: 10.1038/modpathol.2012.202. Epub 2012 Nov 30.


Detection of FLT3 internal tandem duplication in targeted, short-read-length, next-generation sequencing data.

Spencer DH, Abel HJ, Lockwood CM, Payton JE, Szankasi P, Kelley TW, Kulkarni S, Pfeifer JD, Duncavage EJ.

J Mol Diagn. 2013 Jan;15(1):81-93. doi: 10.1016/j.jmoldx.2012.08.001. Epub 2012 Nov 14.


Direct-to-consumer cardiac screening tests: user beware.

Lockwood CM.

Clin Chem. 2012 Jun;58(6):1068-9. No abstract available.


Circulating microRNA miR-323-3p as a biomarker of ectopic pregnancy.

Zhao Z, Zhao Q, Warrick J, Lockwood CM, Woodworth A, Moley KH, Gronowski AM.

Clin Chem. 2012 May;58(5):896-905. doi: 10.1373/clinchem.2011.179283. Epub 2012 Mar 6.


Mechanical scale and load cell underwater weighing: a comparison of simultaneous measurements and the reliability of methods.

Moon JR, Stout JR, Walter AA, Smith AE, Stock MS, Herda TJ, Sherk VD, Young KC, Lockwood CM, Kendall KL, Fukuda DH, Graef JL, Cramer JT, Beck TW, Esposito EN.

J Strength Cond Res. 2011 Mar;25(3):652-61. doi: 10.1519/JSC.0b013e3181e99c2d.


ETRAP (efficient trapping and purification) of target protein polyclonal antibodies from GST-protein immune sera.

Crimmins DL, Brada NA, Lockwood CM, Griest TA, Waldemer RJ, Cervinski MA, Ohlendorf MF, McQuillan JJ, Ladenson JH.

Biotechnol Appl Biochem. 2010 Dec;57(4):127-38. doi: 10.1042/BA20100279.


Physiological effects of caffeine, epigallocatechin-3-gallate, and exercise in overweight and obese women.

Smith AE, Lockwood CM, Moon JR, Kendall KL, Fukuda DH, Tobkin SE, Cramer JT, Stout JR.

Appl Physiol Nutr Metab. 2010 Oct;35(5):607-16. doi: 10.1139/H10-056.


Validation of lamellar body counts using three hematology analyzers.

Lockwood CM, Crompton JC, Riley JK, Landeros K, Dietzen DJ, Grenache DG, Gronowski AM.

Am J Clin Pathol. 2010 Sep;134(3):420-8. doi: 10.1309/AJCPWEUIM2CWUOV8.


Reproducibility and validity of bioimpedance spectroscopy for tracking changes in total body water: implications for repeated measurements.

Moon JR, Stout JR, Smith AE, Tobkin SE, Lockwood CM, Kendall KL, Graef JL, Fukuda DH, Costa PB, Stock MS, Young KC, Tucker PS, Kim E, Herda TJ, Walter AA, Ferguson SL, Sherk VD, Cramer JT.

Br J Nutr. 2010 Nov;104(9):1384-94. doi: 10.1017/S0007114510002254. Epub 2010 Jul 12.


Effect of protein/essential amino acids and resistance training on skeletal muscle hypertrophy: A case for whey protein.

Hulmi JJ, Lockwood CM, Stout JR.

Nutr Metab (Lond). 2010 Jun 17;7:51. doi: 10.1186/1743-7075-7-51.


Mediation analyses: applications in nutrition research and reading the literature.

Lockwood CM, DeFrancesco CA, Elliot DL, Beresford SA, Toobert DJ.

J Am Diet Assoc. 2010 May;110(5):753-62. doi: 10.1016/j.jada.2010.02.005.


The effects of age on skeletal muscle and the phosphocreatine energy system: can creatine supplementation help older adults.

Dalbo VJ, Roberts MD, Lockwood CM, Tucker PS, Kreider RB, Kerksick CM.

Dyn Med. 2009 Dec 24;8:6. doi: 10.1186/1476-5918-8-6.


Low-calorie energy drink improves physiological response to exercise in previously sedentary men: a placebo-controlled efficacy and safety study.

Lockwood CM, Moon JR, Smith AE, Tobkin SE, Kendall KL, Graef JL, Cramer JT, Stout JR.

J Strength Cond Res. 2010 Aug;24(8):2227-38. doi: 10.1519/JSC.0b013e3181aeb0cf. Erratum in: J Strength Cond Res. 2010 Sep;24(9):2574-5.


Validity of electromyographic fatigue threshold as a noninvasive method for tracking changes in ventilatory threshold in college-aged men.

Kendall KL, Smith AE, Graef JL, Walter AA, Moon JR, Lockwood CM, Beck TW, Cramer JT, Stout JR.

J Strength Cond Res. 2010 Jan;24(1):109-13. doi: 10.1519/JSC.0b013e31819b79bc.


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