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Items: 32

1.

Development and Validation of a Gene Signature for Patients with Head and Neck Carcinomas Treated by Postoperative Radio(chemo)therapy.

Schmidt S, Linge A, Zwanenburg A, Leger S, Lohaus F, Krenn C, Appold S, Gudziol V, Nowak A, von Neubeck C, Tinhofer I, Budach V, Sak A, Stuschke M, Balermpas P, Rödel C, Bunea H, Grosu AL, Abdollahi A, Debus J, Ganswindt U, Belka C, Pigorsch S, Combs SE, Mönnich D, Zips D, Baretton GB, Buchholz F, Baumann M, Krause M, Löck S; DKTK-ROG.

Clin Cancer Res. 2018 Jan 3. doi: 10.1158/1078-0432.CCR-17-2345. [Epub ahead of print]

PMID:
29298797
2.

Comparison of detection methods for HPV status as a prognostic marker for loco-regional control after radiochemotherapy in patients with HNSCC.

Linge A, Schötz U, Löck S, Lohaus F, von Neubeck C, Gudziol V, Nowak A, Tinhofer I, Budach V, Sak A, Stuschke M, Balermpas P, Rödel C, Bunea H, Grosu AL, Abdollahi A, Debus J, Ganswindt U, Lauber K, Pigorsch S, Combs SE, Mönnich D, Zips D, Baretton GB, Buchholz F, Krause M, Belka C, Baumann M; DKTK-ROG.

Radiother Oncol. 2017 Dec 30. pii: S0167-8140(17)32762-7. doi: 10.1016/j.radonc.2017.12.007. [Epub ahead of print]

PMID:
29295747
3.

Heat shock protein 70 and tumor-infiltrating NK cells as prognostic indicators for patients with squamous cell carcinoma of the head and neck after radiochemotherapy: A multicentre retrospective study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG).

Stangl S, Tontcheva N, Sievert W, Shevtsov M, Niu M, Schmid TE, Pigorsch S, Combs SE, Haller B, Balermpas P, Rödel F, Rödel C, Fokas E, Krause M, Linge A, Lohaus F, Baumann M, Tinhofer I, Budach V, Stuschke M, Grosu AL, Abdollahi A, Debus J, Belka C, Maihöfer C, Mönnich D, Zips D, Multhoff G.

Int J Cancer. 2017 Dec 13. doi: 10.1002/ijc.31213. [Epub ahead of print]

PMID:
29235112
4.

SDF-1/CXCR4 expression is an independent negative prognostic biomarker in patients with head and neck cancer after primary radiochemotherapy.

De-Colle C, Menegakis A, Mönnich D, Welz S, Boeke S, Sipos B, Fend F, Mauz PS, Tinhofer I, Budach V, Abu Jawad J, Stuschke M, Balermpas P, Rödel C, Grosu AL, Abdollahi A, Debus J, Belka C, Ganswindt U, Pigorsch S, Combs SE, Lohaus F, Linge A, Krause M, Baumann M, Zips D; DKTK-ROG.

Radiother Oncol. 2018 Jan;126(1):125-131. doi: 10.1016/j.radonc.2017.10.008. Epub 2017 Oct 20.

PMID:
29061496
5.

A comparative study of machine learning methods for time-to-event survival data for radiomics risk modelling.

Leger S, Zwanenburg A, Pilz K, Lohaus F, Linge A, Zöphel K, Kotzerke J, Schreiber A, Tinhofer I, Budach V, Sak A, Stuschke M, Balermpas P, Rödel C, Ganswindt U, Belka C, Pigorsch S, Combs SE, Mönnich D, Zips D, Krause M, Baumann M, Troost EGC, Löck S, Richter C.

Sci Rep. 2017 Oct 16;7(1):13206. doi: 10.1038/s41598-017-13448-3.

6.

EGFR-amplification plus gene expression profiling predicts response to combined radiotherapy with EGFR-inhibition: A preclinical trial in 10 HNSCC-tumour-xenograft models.

Koi L, Löck S, Linge A, Thurow C, Hering S, Baumann M, Krause M, Gurtner K.

Radiother Oncol. 2017 Sep;124(3):496-503. doi: 10.1016/j.radonc.2017.07.009. Epub 2017 Aug 11.

PMID:
28807520
7.

The PD-1/PD-L1 axis and human papilloma virus in patients with head and neck cancer after adjuvant chemoradiotherapy: A multicentre study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG).

Balermpas P, Rödel F, Krause M, Linge A, Lohaus F, Baumann M, Tinhofer I, Budach V, Sak A, Stuschke M, Gkika E, Grosu AL, Abdollahi A, Debus J, Stangl S, Ganswindt U, Belka C, Pigorsch S, Multhoff G, Combs SE, Welz S, Zips D, Lim SY, Rödel C, Fokas E; DKTK-ROG.

Int J Cancer. 2017 Aug 1;141(3):594-603. doi: 10.1002/ijc.30770. Epub 2017 May 19.

PMID:
28480996
8.

HPV status, cancer stem cell marker expression, hypoxia gene signatures and tumour volume identify good prognosis subgroups in patients with HNSCC after primary radiochemotherapy: A multicentre retrospective study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG).

Linge A, Lohaus F, Löck S, Nowak A, Gudziol V, Valentini C, von Neubeck C, Jütz M, Tinhofer I, Budach V, Sak A, Stuschke M, Balermpas P, Rödel C, Grosu AL, Abdollahi A, Debus J, Ganswindt U, Belka C, Pigorsch S, Combs SE, Mönnich D, Zips D, Buchholz F, Aust DE, Baretton GB, Thames HD, Dubrovska A, Alsner J, Overgaard J, Krause M, Baumann M; DKTK-ROG.

Radiother Oncol. 2016 Dec;121(3):364-373. doi: 10.1016/j.radonc.2016.11.008. Epub 2016 Nov 29.

PMID:
27913065
9.

Hearing Loss Progresses Faster in Patients With Growing Intracanalicular Vestibular Schwannomas.

van Linge A, Borsboom GJ, Wieringa MH, Goedegebure A.

Otol Neurotol. 2016 Oct;37(9):1442-8. doi: 10.1097/MAO.0000000000001190.

PMID:
27579837
10.

Identifying at diagnosis the vestibular schwannomas at low risk of growth in a long-term retrospective cohort.

Wolbers JG, Dallenga AH, van Linge A, Te West M, Kummer EE, Méndez Romero A, Pauw BK, Wieringa MH.

Clin Otolaryngol. 2016 Dec;41(6):788-792. doi: 10.1111/coa.12661. Epub 2016 May 11.

PMID:
27086938
11.

Targeted next-generation sequencing of locally advanced squamous cell carcinomas of the head and neck reveals druggable targets for improving adjuvant chemoradiation.

Tinhofer I, Budach V, Saki M, Konschak R, Niehr F, Jöhrens K, Weichert W, Linge A, Lohaus F, Krause M, Neumann K, Endris V, Sak A, Stuschke M, Balermpas P, Rödel C, Avlar M, Grosu AL, Abdollahi A, Debus J, Belka C, Pigorsch S, Combs SE, Mönnich D, Zips D, Baumann M; DKTK-ROG.

Eur J Cancer. 2016 Apr;57:78-86. doi: 10.1016/j.ejca.2016.01.003. Epub 2016 Feb 18.

PMID:
26896955
12.

Cancer stem cells: Radioresistance, prediction of radiotherapy outcome and specific targets for combined treatments.

Krause M, Dubrovska A, Linge A, Baumann M.

Adv Drug Deliv Rev. 2017 Jan 15;109:63-73. doi: 10.1016/j.addr.2016.02.002. Epub 2016 Feb 12. Review.

13.

Low Cancer Stem Cell Marker Expression and Low Hypoxia Identify Good Prognosis Subgroups in HPV(-) HNSCC after Postoperative Radiochemotherapy: A Multicenter Study of the DKTK-ROG.

Linge A, Löck S, Gudziol V, Nowak A, Lohaus F, von Neubeck C, Jütz M, Abdollahi A, Debus J, Tinhofer I, Budach V, Sak A, Stuschke M, Balermpas P, Rödel C, Avlar M, Grosu AL, Bayer C, Belka C, Pigorsch S, Combs SE, Welz S, Zips D, Buchholz F, Aust DE, Baretton GB, Thames HD, Dubrovska A, Alsner J, Overgaard J, Baumann M, Krause M; DKTK-ROG.

Clin Cancer Res. 2016 Jun 1;22(11):2639-49. doi: 10.1158/1078-0432.CCR-15-1990. Epub 2016 Jan 11.

14.

Comparative analysis of transcriptomics based hypoxia signatures in head- and neck squamous cell carcinoma.

Tawk B, Schwager C, Deffaa O, Dyckhoff G, Warta R, Linge A, Krause M, Weichert W, Baumann M, Herold-Mende C, Debus J, Abdollahi A.

Radiother Oncol. 2016 Feb;118(2):350-8. doi: 10.1016/j.radonc.2015.11.027. Epub 2015 Dec 19.

PMID:
26711490
15.

HPV and beyond-looking out for biomarkers for distinguishing the good prognosis from the bad prognosis group in locally advanced and clinically high risk HNSCC.

Lohaus F, Linge A, Baumann M.

Ann Transl Med. 2015 Oct;3(17):255. doi: 10.3978/j.issn.2305-5839.2015.09.35. No abstract available.

16.

CD8+ tumour-infiltrating lymphocytes in relation to HPV status and clinical outcome in patients with head and neck cancer after postoperative chemoradiotherapy: A multicentre study of the German cancer consortium radiation oncology group (DKTK-ROG).

Balermpas P, Rödel F, Rödel C, Krause M, Linge A, Lohaus F, Baumann M, Tinhofer I, Budach V, Gkika E, Stuschke M, Avlar M, Grosu AL, Abdollahi A, Debus J, Bayer C, Stangl S, Belka C, Pigorsch S, Multhoff G, Combs SE, Mönnich D, Zips D, Fokas E.

Int J Cancer. 2016 Jan 1;138(1):171-81. doi: 10.1002/ijc.29683. Epub 2015 Jul 30.

17.

HPV16 DNA status is a strong prognosticator of loco-regional control after postoperative radiochemotherapy of locally advanced oropharyngeal carcinoma: results from a multicentre explorative study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG).

Lohaus F, Linge A, Tinhofer I, Budach V, Gkika E, Stuschke M, Balermpas P, Rödel C, Avlar M, Grosu AL, Abdollahi A, Debus J, Bayer C, Belka C, Pigorsch S, Combs SE, Mönnich D, Zips D, von Neubeck C, Baretton GB, Löck S, Thames HD, Krause M, Baumann M; DKTK-ROG.

Radiother Oncol. 2014 Dec;113(3):317-23. doi: 10.1016/j.radonc.2014.11.011. Epub 2014 Dec 2.

18.

Identification and functional validation of RAD23B as a potential protein in human breast cancer progression.

Linge A, Maurya P, Friedrich K, Baretton GB, Kelly S, Henry M, Clynes M, Larkin A, Meleady P.

J Proteome Res. 2014 Jul 3;13(7):3212-22. doi: 10.1021/pr4012156. Epub 2014 Jun 19.

PMID:
24897598
19.

Identification of genes involved in the biology of atypical teratoid/rhabdoid tumours using Drosophila melanogaster.

Jeibmann A, Eikmeier K, Linge A, Kool M, Koos B, Schulz J, Albrecht S, Bartelheim K, Frühwald MC, Pfister SM, Paulus W, Hasselblatt M.

Nat Commun. 2014 Jun 3;5:4005. doi: 10.1038/ncomms5005.

PMID:
24892285
20.

Claudin-2 pore function requires an intramolecular disulfide bond between two conserved extracellular cysteines.

Li J, Angelow S, Linge A, Zhuo M, Yu AS.

Am J Physiol Cell Physiol. 2013 Jul 15;305(2):C190-6. doi: 10.1152/ajpcell.00074.2013. Epub 2013 May 15.

21.

What intervention is best practice for vestibular schwannomas? A systematic review of controlled studies.

Wolbers JG, Dallenga AH, Mendez Romero A, van Linge A.

BMJ Open. 2013 Feb 22;3(2). pii: e001345. doi: 10.1136/bmjopen-2012-001345. Print 2013.

22.

High-resolution genomic analysis suggests the absence of recurrent genomic alterations other than SMARCB1 aberrations in atypical teratoid/rhabdoid tumors.

Hasselblatt M, Isken S, Linge A, Eikmeier K, Jeibmann A, Oyen F, Nagel I, Richter J, Bartelheim K, Kordes U, Schneppenheim R, Frühwald M, Siebert R, Paulus W.

Genes Chromosomes Cancer. 2013 Feb;52(2):185-90. doi: 10.1002/gcc.22018. Epub 2012 Oct 17.

PMID:
23074045
23.

Differential expression of fourteen proteins between uveal melanoma from patients who subsequently developed distant metastases versus those who did Not.

Linge A, Kennedy S, O'Flynn D, Beatty S, Moriarty P, Henry M, Clynes M, Larkin A, Meleady P.

Invest Ophthalmol Vis Sci. 2012 Jul 9;53(8):4634-43. doi: 10.1167/iovs.11-9019.

PMID:
22570344
24.

Bleomycin treatment of A549 human lung cancer cells results in association of MGr1-Ag and caveolin-1 in lipid rafts.

Linge A, Meleady P, Henry M, Clynes M, Kasper M, Barth K.

Int J Biochem Cell Biol. 2011 Jan;43(1):98-105. doi: 10.1016/j.biocel.2010.10.001. Epub 2010 Oct 19.

PMID:
20937408
25.

[The most efficient intervention for vestibular schwannoma].

Wolbers JG, Méndez Romero A, van Linge A, Dallenga AH, Nowak PJ.

Ned Tijdschr Geneeskd. 2010;154:A714. Dutch. No abstract available.

PMID:
20619057
26.

Increased P2X7R expression in atrial cardiomyocytes of caveolin-1 deficient mice.

Barth K, Pfleger C, Linge A, Sim JA, Surprenant A, Steinbronn N, Strasser RH, Kasper M.

Histochem Cell Biol. 2010 Jul;134(1):31-8. doi: 10.1007/s00418-010-0716-8. Epub 2010 Jun 19.

PMID:
20563595
27.

An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis.

van Nederveen FH, Gaal J, Favier J, Korpershoek E, Oldenburg RA, de Bruyn EM, Sleddens HF, Derkx P, Rivière J, Dannenberg H, Petri BJ, Komminoth P, Pacak K, Hop WC, Pollard PJ, Mannelli M, Bayley JP, Perren A, Niemann S, Verhofstad AA, de Bruïne AP, Maher ER, Tissier F, Méatchi T, Badoual C, Bertherat J, Amar L, Alataki D, Van Marck E, Ferrau F, François J, de Herder WW, Peeters MP, van Linge A, Lenders JW, Gimenez-Roqueplo AP, de Krijger RR, Dinjens WN.

Lancet Oncol. 2009 Aug;10(8):764-71. doi: 10.1016/S1470-2045(09)70164-0. Epub 2009 Jul 1.

28.

Characterization of the molecular interaction between caveolin-1 and the P2X receptors 4 and 7 in E10 mouse lung alveolar epithelial cells.

Barth K, Weinhold K, Guenther A, Linge A, Gereke M, Kasper M.

Int J Biochem Cell Biol. 2008;40(10):2230-9. doi: 10.1016/j.biocel.2008.03.001. Epub 2008 Mar 7.

PMID:
18407780
29.

Downregulation of caveolin-1 affects bleomycin-induced growth arrest and cellular senescence in A549 cells.

Linge A, Weinhold K, Bläsche R, Kasper M, Barth K.

Int J Biochem Cell Biol. 2007;39(10):1964-74. Epub 2007 Jun 3.

PMID:
17662641
30.

Bleomycin induces caveolin-1 and -2 expression in epithelial lung cancer A549 cells.

Linge A, Morishima N, Kasper M, Barth K.

Anticancer Res. 2007 May-Jun;27(3A):1343-51.

31.

[Illness due to work or to an overactive thyroid?].

van Linge A, van der Gulden JW, Hermus A.

Ned Tijdschr Geneeskd. 2004 Oct 30;148(44):2157-60. Dutch.

PMID:
15559405
32.

The primary vestibulocerebellar projection in the rabbit: absence of primary afferents in the flocculus.

Gerrits NM, Epema AH, van Linge A, Dalm E.

Neurosci Lett. 1989 Oct 23;105(1-2):27-33.

PMID:
2484730

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