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Items: 1 to 50 of 124

1.

Concurrent Inhibition of Neurosphere and Monolayer Cells of Pediatric Glioblastoma by Aurora A Inhibitor MLN8237 Predicted Survival Extension in PDOX models.

Li XN, Kogiso M, Qi L, Braun FK, Injac SG, Zhang L, Du Y, Zhang H, Lin FY, Zhao S, Lindsay H, Su JM, Baxter PA, Adesina AM, Liao D, Qian MG, Berg SL, Muscal J.

Clin Cancer Res. 2018 Feb 20. pii: clincanres.2256.2017. doi: 10.1158/1078-0432.CCR-17-2256. [Epub ahead of print]

PMID:
29463553
2.

Large-scale image-based profiling of single-cell phenotypes in arrayed CRISPR-Cas9 gene perturbation screens.

de Groot R, Lüthi J, Lindsay H, Holtackers R, Pelkmans L.

Mol Syst Biol. 2018 Jan 23;14(1):e8064. doi: 10.15252/msb.20178064.

3.

Work efficiency improvement of >90% after implementation of an annual inpatient blood products administration consent form.

Lindsay H, Bhar S, Bonifant C, Sartain S, Whittle SB, Lee-Kim Y, Shah MD.

BMJ Open Qual. 2018 Jan 9;7(1):e000164. doi: 10.1136/bmjoq-2017-000164. eCollection 2018.

4.

Pili annulati in a case of Rothmund-Thomson syndrome with a novel frameshift mutation in RECQL4.

Bhoyrul B, Lindsay H, Robinson R, Stahlschmidt J, Palmer T, Edward S, Clark SM.

J Eur Acad Dermatol Venereol. 2017 Dec 10. doi: 10.1111/jdv.14742. [Epub ahead of print] No abstract available.

PMID:
29224249
5.

Xenotransplantation of pediatric low grade gliomas confirms the enrichment of BRAF V600E mutation and preservation of CDKN2A deletion in a novel orthotopic xenograft mouse model of progressive pleomorphic xanthoastrocytoma.

Kogiso M, Qi L, Lindsay H, Huang Y, Zhao X, Liu Z, Braun FK, Du Y, Zhang H, Bae G, Zhao S, Injac SG, Sobieski M, Brunell D, Mehta V, Tran D, Murray J, Baxter PA, Yuan XJ, Su JM, Adesina A, Perlaky L, Chintagumpala M, Parsons DW, Lau CC, Stephan CC, Lu X, Li XN.

Oncotarget. 2017 Sep 8;8(50):87455-87471. doi: 10.18632/oncotarget.20713. eCollection 2017 Oct 20.

6.

Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency.

Hurst CD, Alder O, Platt FM, Droop A, Stead LF, Burns JE, Burghel GJ, Jain S, Klimczak LJ, Lindsay H, Roulson JA, Taylor CF, Thygesen H, Cameron AJ, Ridley AJ, Mott HR, Gordenin DA, Knowles MA.

Cancer Cell. 2017 Nov 13;32(5):701-715.e7. doi: 10.1016/j.ccell.2017.08.005.

PMID:
29136510
7.

Novel histone deacetylase inhibitor N25 exerts anti-tumor effects and induces autophagy in human glioma cells by inhibiting HDAC3.

Sun XY, Qu Y, Ni AR, Wang GX, Huang WB, Chen ZP, Lv ZF, Zhang S, Lindsay H, Zhao S, Li XN, Feng BH.

Oncotarget. 2017 Sep 8;8(43):75232-75242. doi: 10.18632/oncotarget.20744. eCollection 2017 Sep 26.

8.

Highly efficient DNA-free gene disruption in the agricultural pest Ceratitis capitata by CRISPR-Cas9 ribonucleoprotein complexes.

Meccariello A, Monti SM, Romanelli A, Colonna R, Primo P, Inghilterra MG, Del Corsano G, Ramaglia A, Iazzetti G, Chiarore A, Patti F, Heinze SD, Salvemini M, Lindsay H, Chiavacci E, Burger A, Robinson MD, Mosimann C, Bopp D, Saccone G.

Sci Rep. 2017 Aug 30;7(1):10061. doi: 10.1038/s41598-017-10347-5.

9.

A unique enhancer boundary complex on the mouse ribosomal RNA genes persists after loss of Rrn3 or UBF and the inactivation of RNA polymerase I transcription.

Herdman C, Mars JC, Stefanovsky VY, Tremblay MG, Sabourin-Felix M, Lindsay H, Robinson MD, Moss T.

PLoS Genet. 2017 Jul 17;13(7):e1006899. doi: 10.1371/journal.pgen.1006899. eCollection 2017 Jul.

10.

Cip29 is phosphorylated following activation of the DNA damage response in Xenopus egg extracts.

Holden J, Taylor EM, Lindsay HD.

PLoS One. 2017 Jul 17;12(7):e0181131. doi: 10.1371/journal.pone.0181131. eCollection 2017.

11.

Molecular basis for PrimPol recruitment to replication forks by RPA.

Guilliam TA, Brissett NC, Ehlinger A, Keen BA, Kolesar P, Taylor EM, Bailey LJ, Lindsay HD, Chazin WJ, Doherty AJ.

Nat Commun. 2017 May 23;8:15222. doi: 10.1038/ncomms15222.

12.

Neuroprotection during aortic surgery.

Lindsay H, Srinivas C, Djaiani G.

Best Pract Res Clin Anaesthesiol. 2016 Sep;30(3):283-303. doi: 10.1016/j.bpa.2016.05.002. Epub 2016 May 14. Review.

PMID:
27650340
13.

c-Fos over-expression promotes radioresistance and predicts poor prognosis in malignant glioma.

Liu ZG, Jiang G, Tang J, Wang H, Feng G, Chen F, Tu Z, Liu G, Zhao Y, Peng MJ, He ZW, Chen XY, Lindsay H, Xia YF, Li XN.

Oncotarget. 2016 Oct 4;7(40):65946-65956. doi: 10.18632/oncotarget.11779.

14.

Providing HIV results via SMS one day after testing: more popular than rapid point-of-care tests.

Davies SC, Koh A, Lindsay HE, Fulton RB, Fernando SL.

Int J STD AIDS. 2017 Jun;28(7):702-707. doi: 10.1177/0956462416665028. Epub 2016 Aug 18.

PMID:
27538723
15.

CrispRVariants charts the mutation spectrum of genome engineering experiments.

Lindsay H, Burger A, Biyong B, Felker A, Hess C, Zaugg J, Chiavacci E, Anders C, Jinek M, Mosimann C, Robinson MD.

Nat Biotechnol. 2016 Jul 12;34(7):701-2. doi: 10.1038/nbt.3628. No abstract available.

PMID:
27404876
16.

Cefepime-Induced Neurotoxicity Despite Dose Adjustment for Renal Disease: A Brief Report and Review of the Literature.

Lindsay H, Gruner S, Brackett J.

J Pediatric Infect Dis Soc. 2017 Jun 1;6(2):199-201. doi: 10.1093/jpids/piw022.

PMID:
27147713
17.

Breath alcohol of anesthesiologists using alcohol hand gel and the "five moments for hand hygiene" in routine practice.

Lindsay HA, Hannam JA, Bradfield CN, Mitchell SJ.

Can J Anaesth. 2016 Aug;63(8):938-44. doi: 10.1007/s12630-016-0666-2. Epub 2016 May 3.

PMID:
27142004
18.

Maximizing mutagenesis with solubilized CRISPR-Cas9 ribonucleoprotein complexes.

Burger A, Lindsay H, Felker A, Hess C, Anders C, Chiavacci E, Zaugg J, Weber LM, Catena R, Jinek M, Robinson MD, Mosimann C.

Development. 2016 Jun 1;143(11):2025-37. doi: 10.1242/dev.134809. Epub 2016 Apr 29.

19.

Preservation of KIT genotype in a novel pair of patient-derived orthotopic xenograft mouse models of metastatic pediatric CNS germinoma.

Lindsay H, Huang Y, Du Y, Braun FK, Teo WY, Kogiso M, Qi L, Zhang H, Zhao S, Mao H, Lin F, Baxter P, Su JM, Terashima K, Perlaky L, Chintagumpala M, Adesina A, Lau CC, Williams Parsons D, Li XN.

J Neurooncol. 2016 May;128(1):47-56. doi: 10.1007/s11060-016-2098-9. Epub 2016 Mar 8.

PMID:
26956263
20.

Correction: Mechanisms That Determine the Internal Environment of the Developing Brain: A Transcriptomic, Functional and Ultrastructural Approach.

Liddelow SA, Dziegielewska KM, Ek CJ, Habgood MD, Bauer H, Bauer HC, Lindsay H, Wakefield MJ, Strazielle N, Kratzer I, Møllgård K, Ghersi-Egea JF, Saunders NR.

PLoS One. 2016 Jan 19;11(1):e0147680. doi: 10.1371/journal.pone.0147680. eCollection 2016. No abstract available.

21.

DNA replication stress and cancer: cause or cure?

Taylor EM, Lindsay HD.

Future Oncol. 2016 Jan;12(2):221-37. doi: 10.2217/fon.15.292. Epub 2015 Nov 30. Review.

PMID:
26616915
22.

Perioperative Hemostatic Management in Ehlers-Danlos Syndrome: A Report of 2 Cases and Literature Review.

Lindsay H, Lee-Kim YJ, Srivaths LV.

J Pediatr Hematol Oncol. 2016 Mar;38(2):158-60. doi: 10.1097/MPH.0000000000000422. Review.

PMID:
26334432
23.

Influx mechanisms in the embryonic and adult rat choroid plexus: a transcriptome study.

Saunders NR, Dziegielewska KM, Møllgård K, Habgood MD, Wakefield MJ, Lindsay H, Stratzielle N, Ghersi-Egea JF, Liddelow SA.

Front Neurosci. 2015 Apr 28;9:123. doi: 10.3389/fnins.2015.00123. eCollection 2015.

24.

Cytogenetic landscape of paired neurospheres and traditional monolayer cultures in pediatric malignant brain tumors.

Zhao X, Zhao YJ, Lin Q, Yu L, Liu Z, Lindsay H, Kogiso M, Rao P, Li XN, Lu X.

Neuro Oncol. 2015 Jul;17(7):965-77. doi: 10.1093/neuonc/nou337. Epub 2014 Dec 23.

25.

Statistical methods for detecting differentially methylated loci and regions.

Robinson MD, Kahraman A, Law CW, Lindsay H, Nowicka M, Weber LM, Zhou X.

Front Genet. 2014 Sep 16;5:324. doi: 10.3389/fgene.2014.00324. eCollection 2014. Review.

26.

Injuries and helmet use related to non-motorized wheeled activities among pediatric patients.

Lindsay H, Brussoni M.

Chronic Dis Inj Can. 2014 Jul;34(2-3):74-81. English, French.

27.

Age-dependent transcriptome and proteome following transection of neonatal spinal cord of Monodelphis domestica (South American grey short-tailed opossum).

Saunders NR, Noor NM, Dziegielewska KM, Wheaton BJ, Liddelow SA, Steer DL, Ek CJ, Habgood MD, Wakefield MJ, Lindsay H, Truettner J, Miller RD, Smith AI, Dietrich WD.

PLoS One. 2014 Jun 10;9(6):e99080. doi: 10.1371/journal.pone.0099080. eCollection 2014.

28.

Robustly detecting differential expression in RNA sequencing data using observation weights.

Zhou X, Lindsay H, Robinson MD.

Nucleic Acids Res. 2014 Jun;42(11):e91. doi: 10.1093/nar/gku310. Epub 2014 Apr 20.

29.

Co-inheritance of mild hemophilia A and heterozygosity for type 2N von Willebrand disease: a diagnostic and therapeutic challenge.

Lindsay H, Bergstrom K, Srivaths L.

Pediatr Blood Cancer. 2014 Oct;61(10):1888-90. doi: 10.1002/pbc.25054. Epub 2014 Apr 7.

PMID:
24706524
30.

Oral pyogenic granuloma in hemophilia: a report of 2 cases.

Lindsay H, Srivaths LV.

J Pediatr Hematol Oncol. 2014 Jul;36(5):e333-4. doi: 10.1097/MPH.0000000000000155.

PMID:
24663071
31.

Acute, symptomatic catheter-associated DVT with mobile, intra-cardiac thrombus in an infant with severe haemophilia A.

Lindsay H, Yates A, Yee DL.

Haemophilia. 2014 Mar;20(2):e182-4. doi: 10.1111/hae.12367. Epub 2014 Jan 24. No abstract available.

PMID:
24456104
32.

Microbiota-derived hydrogen fuels Salmonella typhimurium invasion of the gut ecosystem.

Maier L, Vyas R, Cordova CD, Lindsay H, Schmidt TS, Brugiroux S, Periaswamy B, Bauer R, Sturm A, Schreiber F, von Mering C, Robinson MD, Stecher B, Hardt WD.

Cell Host Microbe. 2013 Dec 11;14(6):641-51. doi: 10.1016/j.chom.2013.11.002.

33.

Robust diagnostic genetic testing using solution capture enrichment and a novel variant-filtering interface.

Watson CM, Crinnion LA, Morgan JE, Harrison SM, Diggle CP, Adlard J, Lindsay HA, Camm N, Charlton R, Sheridan E, Bonthron DT, Taylor GR, Carr IM.

Hum Mutat. 2014 Apr;35(4):434-41. doi: 10.1002/humu.22490.

34.

PrimPol bypasses UV photoproducts during eukaryotic chromosomal DNA replication.

Bianchi J, Rudd SG, Jozwiakowski SK, Bailey LJ, Soura V, Taylor E, Stevanovic I, Green AJ, Stracker TH, Lindsay HD, Doherty AJ.

Mol Cell. 2013 Nov 21;52(4):566-73. doi: 10.1016/j.molcel.2013.10.035.

35.

Mechanisms that determine the internal environment of the developing brain: a transcriptomic, functional and ultrastructural approach.

Liddelow SA, Dziegielewska KM, Ek CJ, Habgood MD, Bauer H, Bauer HC, Lindsay H, Wakefield MJ, Strazielle N, Kratzer I, Møllgård K, Ghersi-Egea JF, Saunders NR.

PLoS One. 2013 Jul 2;8(7):e65629. doi: 10.1371/journal.pone.0065629. Print 2013. Erratum in: PLoS One. 2016;11(1):e0147680.

36.

Depletion of Uhrf1 inhibits chromosomal DNA replication in Xenopus egg extracts.

Taylor EM, Bonsu NM, Price RJ, Lindsay HD.

Nucleic Acids Res. 2013 Sep;41(16):7725-37. doi: 10.1093/nar/gkt549. Epub 2013 Jun 20.

37.

Simultaneous colonic adenocarcinoma and medulloblastoma in a 12-year-old with biallelic deletions in PMS2.

Lindsay H, Jubran RF, Wang L, Kipp BR, May WA.

J Pediatr. 2013 Aug;163(2):601-3. doi: 10.1016/j.jpeds.2013.03.007. Epub 2013 Apr 10.

38.

Founder mutations and genotype-phenotype correlations in Meckel-Gruber syndrome and associated ciliopathies.

Szymanska K, Berry I, Logan CV, Cousins SR, Lindsay H, Jafri H, Raashid Y, Malik-Sharif S, Castle B, Ahmed M, Bennett C, Carlton R, Johnson CA.

Cilia. 2012 Oct 1;1(1):18. doi: 10.1186/2046-2530-1-18.

39.

Anaphylactic reaction to etoposide phosphate.

Lindsay H, Gaynon P.

Pediatr Blood Cancer. 2012 Oct;59(4):765. doi: 10.1002/pbc.24183. Epub 2012 Apr 22. No abstract available.

PMID:
22522419
40.

Meticillin-resistant Staphylococcus aureus with a novel mecA homologue in human and bovine populations in the UK and Denmark: a descriptive study.

García-Álvarez L, Holden MT, Lindsay H, Webb CR, Brown DF, Curran MD, Walpole E, Brooks K, Pickard DJ, Teale C, Parkhill J, Bentley SD, Edwards GF, Girvan EK, Kearns AM, Pichon B, Hill RL, Larsen AR, Skov RL, Peacock SJ, Maskell DJ, Holmes MA.

Lancet Infect Dis. 2011 Aug;11(8):595-603. doi: 10.1016/S1473-3099(11)70126-8.

41.

Genetic diagnosis of familial breast cancer using clonal sequencing.

Morgan JE, Carr IM, Sheridan E, Chu CE, Hayward B, Camm N, Lindsay HA, Mattocks CJ, Markham AF, Bonthron DT, Taylor GR.

Hum Mutat. 2010 Apr;31(4):484-91. doi: 10.1002/humu.21216.

PMID:
20127978
43.

How do patients with inflammatory bowel disease want their biological therapy administered?

Allen PB, Lindsay H, Tham TC.

BMC Gastroenterol. 2010 Jan 10;10:1. doi: 10.1186/1471-230X-10-1.

44.

The Mre11/Rad50/Nbs1 complex functions in resection-based DNA end joining in Xenopus laevis.

Taylor EM, Cecillon SM, Bonis A, Chapman JR, Povirk LF, Lindsay HD.

Nucleic Acids Res. 2010 Jan;38(2):441-54. doi: 10.1093/nar/gkp905. Epub 2009 Nov 5.

45.

Estimates of the effect of natural selection on protein-coding content.

Yap VB, Lindsay H, Easteal S, Huttley G.

Mol Biol Evol. 2010 Mar;27(3):726-34. doi: 10.1093/molbev/msp232. Epub 2009 Oct 8.

46.

Pitfalls of the most commonly used models of context dependent substitution.

Lindsay H, Yap VB, Ying H, Huttley GA.

Biol Direct. 2008 Dec 16;3:52. doi: 10.1186/1745-6150-3-52. Erratum in: Biol Direct. 2009;(4). doi: 10.1186/1745-6150-4-10.

47.

The dominant cold-sensitive Out-cold mutants of Drosophila melanogaster have novel missense mutations in the voltage-gated sodium channel gene paralytic.

Lindsay HA, Baines R, ffrench-Constant R, Lilley K, Jacobs HT, O'Dell KM.

Genetics. 2008 Oct;180(2):873-84. doi: 10.1534/genetics.108.090951. Epub 2008 Aug 24.

48.

PyCogent: a toolkit for making sense from sequence.

Knight R, Maxwell P, Birmingham A, Carnes J, Caporaso JG, Easton BC, Eaton M, Hamady M, Lindsay H, Liu Z, Lozupone C, McDonald D, Robeson M, Sammut R, Smit S, Wakefield MJ, Widmann J, Wikman S, Wilson S, Ying H, Huttley GA.

Genome Biol. 2007;8(8):R171.

49.

Approach to the synthesis of cladiell-11-ene-3,6,7-triol.

Hutchison JM, Lindsay HA, Dormi SS, Jones GD, Vicic DA, McIntosh MC.

Org Lett. 2006 Aug 17;8(17):3663-5.

PMID:
16898786
50.

Direct requirement for Xmus101 in ATR-mediated phosphorylation of Claspin bound Chk1 during checkpoint signaling.

Yan S, Lindsay HD, Michael WM.

J Cell Biol. 2006 Apr 24;173(2):181-6. Epub 2006 Apr 17.

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