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Items: 32

1.

Prostate cancers that 'Wnt' respond to abiraterone.

Linch M, Attard G.

Ann Oncol. 2018 Feb 1;29(2):290-292. doi: 10.1093/annonc/mdx785. No abstract available.

PMID:
29240904
2.

Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters.

Linch M, Goh G, Hiley C, Shanmugabavan Y, McGranahan N, Rowan A, Wong YNS, King H, Furness A, Freeman A, Linares J, Akarca A, Herrero J, Rosenthal R, Harder N, Schmidt G, Wilson GA, Birkbak NJ, Mitter R, Dentro S, Cathcart P, Arya M, Johnston E, Scott R, Hung M, Emberton M, Attard G, Szallasi Z, Punwani S, Quezada SA, Marafioti T, Gerlinger M, Ahmed HU, Swanton C.

Ann Oncol. 2017 Oct 1;28(10):2472-2480. doi: 10.1093/annonc/mdx355.

PMID:
28961847
3.

Response Rate to Chemotherapy After Immune Checkpoint Inhibition in Metastatic Urothelial Cancer.

Szabados B, van Dijk N, Tang YZ, van der Heijden MS, Wimalasingham A, Gomez de Liano A, Chowdhury S, Hughes S, Rudman S, Linch M, Powles T.

Eur Urol. 2018 Feb;73(2):149-152. doi: 10.1016/j.eururo.2017.08.022. Epub 2017 Sep 13.

PMID:
28917596
4.

Evolving adoptive cellular therapies in urological malignancies.

Wong YNS, Joshi K, Pule M, Peggs KS, Swanton C, Quezada SA, Linch M.

Lancet Oncol. 2017 Jun;18(6):e341-e353. doi: 10.1016/S1470-2045(17)30327-3. Review.

PMID:
28593860
5.

aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization.

Soriano EV, Ivanova ME, Fletcher G, Riou P, Knowles PP, Barnouin K, Purkiss A, Kostelecky B, Saiu P, Linch M, Elbediwy A, Kjær S, O'Reilly N, Snijders AP, Parker PJ, Thompson BJ, McDonald NQ.

Dev Cell. 2016 Aug 22;38(4):384-98. doi: 10.1016/j.devcel.2016.07.018.

6.

First line palliative chemotherapy in elderly patients with advanced soft tissue sarcoma.

Yousaf N, Harris S, Martin-Liberal J, Stanway S, Linch M, Ifijen M, Al Muderis O, Khabra K, Fisher C, Noujaim J, Judson I, Benson C.

Clin Sarcoma Res. 2015 Mar 24;5:10. doi: 10.1186/s13569-015-0026-y. eCollection 2015.

7.

Targeting protein kinase C in sarcoma.

Martin-Liberal J, Cameron AJ, Claus J, Judson IR, Parker PJ, Linch M.

Biochim Biophys Acta. 2014 Dec;1846(2):547-59. doi: 10.1016/j.bbcan.2014.10.002. Epub 2014 Oct 16. Review.

PMID:
25453364
8.

PDT with a glucose-conjugated chlorin for GIST--letter.

Linch M, Hayes AJ.

Mol Cancer Ther. 2014 Nov;13(11):2763. doi: 10.1158/1535-7163.MCT-14-0390. Epub 2014 Oct 8. No abstract available.

9.

A serum mesothelin level is a prognostic indicator for patients with malignant mesothelioma in routine clinical practice.

Linch M, Gennatas S, Kazikin S, Iqbal J, Gunapala R, Priest K, Severn J, Norton A, Ayite B, Bhosle J, O'Brien M, Popat S.

BMC Cancer. 2014 Sep 17;14:674. doi: 10.1186/1471-2407-14-674.

10.

Control of MT1-MMP transport by atypical PKC during breast-cancer progression.

Rossé C, Lodillinsky C, Fuhrmann L, Nourieh M, Monteiro P, Irondelle M, Lagoutte E, Vacher S, Waharte F, Paul-Gilloteaux P, Romao M, Sengmanivong L, Linch M, van Lint J, Raposo G, Vincent-Salomon A, Bièche I, Parker PJ, Chavrier P.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):E1872-9. doi: 10.1073/pnas.1400749111. Epub 2014 Apr 21.

11.

Nonsurgical oncological management of cancer pain.

Gough N, Miah AB, Linch M.

Curr Opin Support Palliat Care. 2014 Jun;8(2):102-11. doi: 10.1097/SPC.0000000000000043. Review.

PMID:
24675403
12.

Systemic treatment of soft-tissue sarcoma-gold standard and novel therapies.

Linch M, Miah AB, Thway K, Judson IR, Benson C.

Nat Rev Clin Oncol. 2014 Apr;11(4):187-202. doi: 10.1038/nrclinonc.2014.26. Epub 2014 Mar 18. Review.

PMID:
24642677
13.

Functional implications of assigned, assumed and assembled PKC structures.

Linch M, Riou P, Claus J, Cameron AJ, de Naurois J, Larijani B, Ng T, McDonald NQ, Parker PJ.

Biochem Soc Trans. 2014 Feb;42(1):35-41. doi: 10.1042/BST20130192.

PMID:
24450624
14.

Fistulation as a complication of intra-abdominal soft-tissue sarcomas; a case series.

Wang B, Thomas R, Moskovic E, Benson C, Linch M.

J Radiol Case Rep. 2013 Jun 1;7(6):15-21. doi: 10.3941/jrcr.v7i6.1436. eCollection 2013 Jun.

15.

Regorafenib treatment for advanced, refractory gastrointestinal stromal tumor: a report of the UK managed access program.

Kollàr A, Maruzzo M, Messiou C, Cartwright E, Miah A, Martin-Liberal J, Thway K, McGrath E, Dunlop A, Khabra K, Seddon B, Dileo P, Linch M, Judson I, Benson C.

Clin Sarcoma Res. 2014 Dec 4;4:17. doi: 10.1186/2045-3329-4-17. eCollection 2014.

16.

Clinical activity and tolerability of a 14-day infusional Ifosfamide schedule in soft-tissue sarcoma.

Martin-Liberal J, Alam S, Constantinidou A, Fisher C, Khabra K, Messiou C, Olmos D, Mitchell S, Al-Muderis O, Miah A, Linch M, Jones RL, Scurr M, Judson I, Benson C.

Sarcoma. 2013;2013:868973. doi: 10.1155/2013/868973. Epub 2013 Dec 4.

17.
18.

Atypical protein kinase Cι as a human oncogene and therapeutic target.

Parker PJ, Justilien V, Riou P, Linch M, Fields AP.

Biochem Pharmacol. 2014 Mar 1;88(1):1-11. doi: 10.1016/j.bcp.2013.10.023. Epub 2013 Nov 11. Review.

19.

Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids.

Linch M, Sanz-Garcia M, Rosse C, Riou P, Peel N, Madsen CD, Sahai E, Downward J, Khwaja A, Dillon C, Roffey J, Cameron AJ, Parker PJ.

Carcinogenesis. 2014 Feb;35(2):396-406. doi: 10.1093/carcin/bgt313. Epub 2013 Sep 26.

20.

A cancer-associated mutation in atypical protein kinase Cι occurs in a substrate-specific recruitment motif.

Linch M, Sanz-Garcia M, Soriano E, Zhang Y, Riou P, Rosse C, Cameron A, Knowles P, Purkiss A, Kjaer S, McDonald NQ, Parker PJ.

Sci Signal. 2013 Sep 17;6(293):ra82. doi: 10.1126/scisignal.2004068.

PMID:
24045153
21.

Update on imatinib for gastrointestinal stromal tumors: duration of treatment.

Linch M, Claus J, Benson C.

Onco Targets Ther. 2013 Jul 30;6:1011-23. doi: 10.2147/OTT.S31260. Print 2013.

22.

Utility values for advanced soft tissue sarcoma health States from the general public in the United kingdom.

Guest JF, Sladkevicius E, Gough N, Linch M, Grimer R.

Sarcoma. 2013;2013:863056. doi: 10.1155/2013/863056. Epub 2013 Mar 17.

23.

Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes.

Kjær S, Linch M, Purkiss A, Kostelecky B, Knowles PP, Rosse C, Riou P, Soudy C, Kaye S, Patel B, Soriano E, Murray-Rust J, Barton C, Dillon C, Roffey J, Parker PJ, McDonald NQ.

Biochem J. 2013 Apr 15;451(2):329-42. doi: 10.1042/BJ20121871.

PMID:
23418854
24.

Binding of dynein intermediate chain 2 to paxillin controls focal adhesion dynamics and migration.

Rosse C, Boeckeler K, Linch M, Radtke S, Frith D, Barnouin K, Morsi AS, Hafezparast M, Howell M, Parker PJ.

J Cell Sci. 2012 Aug 15;125(Pt 16):3733-8. doi: 10.1242/jcs.089557. Epub 2012 May 2.

25.

mTORC2 targets AGC kinases through Sin1-dependent recruitment.

Cameron AJ, Linch MD, Saurin AT, Escribano C, Parker PJ.

Biochem J. 2011 Oct 15;439(2):287-97. doi: 10.1042/BJ20110678.

PMID:
21806543
26.

PKC and the control of localized signal dynamics.

Rosse C, Linch M, Kermorgant S, Cameron AJ, Boeckeler K, Parker PJ.

Nat Rev Mol Cell Biol. 2010 Feb;11(2):103-12. doi: 10.1038/nrm2847. Review.

PMID:
20094051
27.

Protein kinase C intervention: the state of play.

Roffey J, Rosse C, Linch M, Hibbert A, McDonald NQ, Parker PJ.

Curr Opin Cell Biol. 2009 Apr;21(2):268-79. doi: 10.1016/j.ceb.2009.01.019. Epub 2009 Feb 23. Review.

PMID:
19233632
28.

Experience in a UK cancer centre of weekly paclitaxel in the treatment of relapsed ovarian and primary peritoneal cancer.

Linch M, Stavridi F, Hook J, Barbachano Y, Gore M, Kaye SB.

Gynecol Oncol. 2008 Apr;109(1):27-32. doi: 10.1016/j.ygyno.2008.01.007. Epub 2008 Feb 8.

PMID:
18262259
29.

Renal tubular acidosis due to oxaliplatin.

Linch M, Cunningham D, Mingo O, Stiles A, Farquhar-Smith WP.

Ann Oncol. 2007 Apr;18(4):805-6. No abstract available.

PMID:
17389529
30.

Novel therapeutic agents in ovarian cancer.

Agarwal R, Linch M, Kaye SB.

Eur J Surg Oncol. 2006 Oct;32(8):875-86. Epub 2006 May 15. Review.

PMID:
16704916
31.

Variable use of endoscopic haemostasis in the management of bleeding peptic ulcers.

Mahadeva S, Linch M, Hull MA.

Postgrad Med J. 2002 Jun;78(920):347-51.

32.

A SHORT METHOD FOR THE PREPARATION OF ANIMAL TISSUES FOR STAINING.

Bowman PW, Linch MN.

Science. 1931 Oct 30;74(1922):440. No abstract available.

PMID:
17793909

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